Motif ID: CREB1.p2

Z-value: 2.509


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_2081030010.263.3e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_+_32755778 6.921 NM_021202
 TP53INP2
tumor protein p53 inducible nuclear protein 2
chr2_-_128285136 4.068 WDR33
WD repeat domain 33
chr2_-_128285214 3.726 NM_001006622
NM_001006623
NM_018383
 WDR33


WD repeat domain 33


chr13_+_48720047 3.672 NM_001193478
NM_030911
 CDADC1

cytidine and dCMP deaminase domain containing 1

chr1_+_119484529 3.642


chr7_-_19715127 3.218 NM_001002926
 TWISTNB
TWIST neighbor
chr1_+_169721260 3.124 NM_015172
 PRRC2C
proline-rich coiled-coil 2C
chr2_-_43676603 3.035 NM_001083953
NM_022065
 THADA

thyroid adenoma associated

chr5_-_172130766 2.916 NM_004417
 DUSP1
dual specificity phosphatase 1
chr2_+_192251105 2.753 NM_001031716
 OBFC2A
oligonucleotide/oligosaccharide-binding fold containing 2A
chr16_+_18986459 2.504 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr6_+_126319540 2.473 NM_138571
 HINT3
histidine triad nucleotide binding protein 3
chr5_-_133332173 2.472 NM_020199
 C5orf15
chromosome 5 open reading frame 15
chr2_-_179051471 2.434 NM_001135212
NM_181342
 FKBP7

FK506 binding protein 7

chr14_+_34521945 2.419 SRP54
signal recognition particle 54kDa
chr2_+_95432150 2.299 NM_016044
 FAHD2A
fumarylacetoacetate hydrolase domain containing 2A
chr2_+_219453487 2.289 NM_025216
 WNT10A
wingless-type MMTV integration site family, member 10A
chr17_-_35337288 2.286 NM_139280
 ORMDL3
ORM1-like 3 (S. cerevisiae)
chr16_-_3707450 2.215 NM_016292
 TRAP1
TNF receptor-associated protein 1
chr20_+_36810510 2.214 NM_024855
 ACTR5
ARP5 actin-related protein 5 homolog (yeast)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 88 entries
enrichment   p-value GO term description
3.91 7.24e-03 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
3.45 1.11e-02 GO:0031124 mRNA 3'-end processing
3.08 4.43e-04 GO:0051028 mRNA transport
3.07 3.51e-02 GO:0031123 RNA 3'-end processing
3.04 1.19e-04 GO:0006403 RNA localization
3.03 2.10e-04 GO:0050657 nucleic acid transport
3.03 2.10e-04 GO:0050658 RNA transport
3.03 2.10e-04 GO:0051236 establishment of RNA localization
2.71 1.67e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.62 8.01e-03 GO:0048193 Golgi vesicle transport
2.53 2.15e-04 GO:0000375 RNA splicing, via transesterification reactions
2.53 3.20e-04 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.53 3.20e-04 GO:0000398 nuclear mRNA splicing, via spliceosome
2.35 1.42e-05 GO:0008380 RNA splicing
2.29 2.96e-03 GO:0009261 ribonucleotide catabolic process
2.26 1.04e-04 GO:0000087 M phase of mitotic cell cycle
2.25 6.22e-03 GO:0009154 purine ribonucleotide catabolic process
2.23 3.59e-07 GO:0000279 M phase
2.23 1.03e-02 GO:0009203 ribonucleoside triphosphate catabolic process
2.23 1.03e-02 GO:0009207 purine ribonucleoside triphosphate catabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
3.07 3.44e-03 GO:0071013 catalytic step 2 spliceosome
2.79 1.50e-04 GO:0005681 spliceosomal complex
2.24 4.99e-02 GO:0000775 chromosome, centromeric region
2.09 8.09e-03 GO:0016604 nuclear body
1.92 2.48e-05 GO:0005730 nucleolus
1.84 1.96e-13 GO:0005654 nucleoplasm
1.84 6.58e-05 GO:0005694 chromosome
1.82 1.15e-03 GO:0044427 chromosomal part
1.77 7.10e-17 GO:0031981 nuclear lumen
1.75 2.23e-19 GO:0044428 nuclear part
1.70 8.06e-03 GO:0030529 ribonucleoprotein complex
1.67 2.01e-16 GO:0070013 intracellular organelle lumen
1.67 5.13e-04 GO:0044451 nucleoplasm part
1.65 1.63e-15 GO:0043233 organelle lumen
1.63 4.10e-15 GO:0031974 membrane-enclosed lumen
1.48 1.41e-07 GO:0005829 cytosol
1.41 4.97e-11 GO:0032991 macromolecular complex
1.40 6.52e-20 GO:0005634 nucleus
1.40 1.27e-19 GO:0044446 intracellular organelle part
1.39 4.93e-19 GO:0044422 organelle part

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
3.31 1.69e-02 GO:0004221 ubiquitin thiolesterase activity
2.11 5.33e-03 GO:0019787 small conjugating protein ligase activity
2.06 2.00e-02 GO:0004842 ubiquitin-protein ligase activity
2.02 2.19e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
2.00 9.30e-03 GO:0016881 acid-amino acid ligase activity
1.93 1.28e-09 GO:0003723 RNA binding
1.55 1.65e-02 GO:0017111 nucleoside-triphosphatase activity
1.54 1.35e-02 GO:0016462 pyrophosphatase activity
1.54 1.57e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.53 1.83e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
1.43 7.87e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.42 2.73e-06 GO:0000166 nucleotide binding
1.41 3.10e-03 GO:0005524 ATP binding
1.40 2.57e-04 GO:0032553 ribonucleotide binding
1.40 2.57e-04 GO:0032555 purine ribonucleotide binding
1.39 3.81e-04 GO:0017076 purine nucleotide binding
1.39 7.27e-03 GO:0032559 adenyl ribonucleotide binding
1.38 9.82e-03 GO:0030554 adenyl nucleotide binding
1.32 7.42e-06 GO:0003676 nucleic acid binding
1.23 2.76e-10 GO:0005515 protein binding