Motif ID: CTCF.p2

Z-value: 1.510


Transcription factors associated with CTCF.p2:

Gene SymbolEntrez IDGene Name
CTCF 10664 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CTCFchr16_+_661538100.361.7e-01Click!


Activity profile for motif CTCF.p2.

activity profile for motif CTCF.p2


Sorted Z-values histogram for motif CTCF.p2

Sorted Z-values for motif CTCF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CTCF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_2580296 1.727 NM_152554
C6orf195
chromosome 6 open reading frame 195
chr20_+_36663865 1.484 NM_001164431
ARHGAP40
Rho GTPase activating protein 40
chr19_-_40693176 1.451 NM_001126059
DMKN
dermokine
chr22_-_16887151 1.439 NM_001122731
NM_001136004
NM_015241
MICAL3


microtubule associated monoxygenase, calponin and LIM domain containing 3


chr5_+_157103280 1.358 NM_173491
LSM11
LSM11, U7 small nuclear RNA associated
chr2_+_69093641 1.341 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr1_+_183970093 1.280 NM_031935
HMCN1
hemicentin 1
chr17_-_31146660 1.239 NM_001032278
NM_024302
MMP28

matrix metallopeptidase 28

chr1_-_158182006 1.196 NM_001135050
NM_020789
IGSF9

immunoglobulin superfamily, member 9

chr1_-_33669190 1.190 PHC2
polyhomeotic homolog 2 (Drosophila)
chr5_-_125958503 1.176 NM_001182
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr14_+_51188289 1.161 NM_152330
FRMD6
FERM domain containing 6
chr15_-_69194854 1.143 NM_001102658
CT62
cancer/testis antigen 62
chr22_+_21742364 1.128 NM_002073
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr15_-_42274529 1.097 NM_032892
FRMD5
FERM domain containing 5
chr10_-_49534304 1.095 ARHGAP22
Rho GTPase activating protein 22
chr5_+_148501178 1.093 NM_014945
ABLIM3
actin binding LIM protein family, member 3
chr22_+_21742727 1.018 GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr2_-_86889029 1.005 NM_001145873
CD8A
CD8a molecule
chr6_+_139055244 0.945 FLJ46906
hypothetical LOC441172
chr20_-_45848684 0.941 NM_001161841
NM_198596
SULF2

sulfatase 2

chr3_+_50167424 0.916 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr22_-_21231421 0.908 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr1_-_40140126 0.895 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chr6_-_18230829 0.890 NM_198586
NHLRC1
NHL repeat containing 1
chr16_-_21919928 0.885 NM_173806
PDZD9
PDZ domain containing 9
chr20_-_42373151 0.881 NM_001080472
FITM2
fat storage-inducing transmembrane protein 2
chr17_-_75624048 0.860 NM_019020
TBC1D16
TBC1 domain family, member 16
chr10_-_92607397 0.859 HTR7
5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
chr15_+_99207555 0.842 LOC145757
hypothetical LOC145757
chr10_-_30064600 0.827 NM_003174
SVIL
supervillin
chr6_+_6670117 0.824


chr5_+_98132898 0.817 NM_001012761
RGMB
RGM domain family, member B
chr14_-_74148422 0.807 NM_000428
LTBP2
latent transforming growth factor beta binding protein 2
chr12_-_49950236 0.804 NM_001033873
NM_001031628
SMAGP

small cell adhesion glycoprotein

chr15_-_42274760 0.800 FRMD5
FERM domain containing 5
chr12_+_118590039 0.799 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr20_+_29492071 0.795 NM_153324
DEFB123
defensin, beta 123
chr16_-_23515104 0.793 NM_005003
NDUFAB1
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
chr17_-_59342319 0.785 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chr5_+_54491702 0.782 NM_001008397
GPX8
glutathione peroxidase 8 (putative)
chr1_+_32979930 0.763 NM_020888
KIAA1522
KIAA1522
chrX_+_122922058 0.750 NM_001042749
STAG2
stromal antigen 2
chr6_-_30151526 0.740 NM_170769
NM_025236
RNF39

ring finger protein 39

chr2_+_171493870 0.739 NM_015530
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr16_+_30903963 0.738 NM_001142777
NM_001142778
NM_025193
HSD3B7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr12_+_103133631 0.732 NM_001093771
TXNRD1
thioredoxin reductase 1
chr17_+_75625025 0.732 NM_017950
CCDC40
coiled-coil domain containing 40
chr2_-_85969527 0.720 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr22_+_21027538 0.717


chr19_+_52908412 0.714 NM_014601
EHD2
EH-domain containing 2
chr9_-_38059207 0.702 NM_003028
SHB
Src homology 2 domain containing adaptor protein B
chr2_+_171494026 0.700 GORASP2
golgi reassembly stacking protein 2, 55kDa
chr12_+_47494882 0.685 CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr12_+_62523648 0.675


chr14_-_106154332 0.671 LOC100126583
IGHG1
hypothetical LOC100126583
immunoglobulin heavy constant gamma 1 (G1m marker)
chr4_+_152417774 0.663 NM_183375
PRSS48
protease, serine, 48
chr22_-_20637188 0.656 PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr6_-_33028790 0.655 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr1_-_17638797 0.652 NM_018715
RCC2
regulator of chromosome condensation 2
chr11_-_44928803 0.651 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr7_-_27149750 0.636 NM_019102
HOXA5
homeobox A5
chr16_+_51646292 0.634 NM_025134
CHD9
chromodomain helicase DNA binding protein 9
chr1_+_161308318 0.632 NM_001113380
RGS4
regulator of G-protein signaling 4
chr11_-_65962836 0.628 NM_016050
NM_170738
NM_170739
MRPL11


mitochondrial ribosomal protein L11


chr2_+_182464910 0.627 SSFA2
sperm specific antigen 2
chr2_-_166518500 0.613 NM_024753
TTC21B
tetratricopeptide repeat domain 21B
chr9_-_129993615 0.612 NM_001131016
NM_001131017
NM_001131018
CIZ1


CDKN1A interacting zinc finger protein 1


chr1_+_27591738 0.607 NM_005281
GPR3
G protein-coupled receptor 3
chr1_-_37752925 0.599 NM_022756
MEAF6
MYST/Esa1-associated factor 6
chr6_+_138767151 0.587 HEBP2
heme binding protein 2
chr3_+_38010618 0.584 VILL
villin-like
chr10_-_92607650 0.575 NM_000872
NM_019859
NM_019860
HTR7


5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)


chr20_-_32924219 0.570 NM_178026
GGT7
gamma-glutamyltransferase 7
chr12_-_54869511 0.563 SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr9_-_139060416 0.563 NM_015392
NPDC1
neural proliferation, differentiation and control, 1
chr1_-_93919789 0.561 NM_003567
BCAR3
breast cancer anti-estrogen resistance 3
chr3_-_38046034 0.561 NM_006225
PLCD1
phospholipase C, delta 1
chr9_-_38059082 0.560 SHB
Src homology 2 domain containing adaptor protein B
chr4_-_140436401 0.546 NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr7_+_99919485 0.543 NM_173564
C7orf51
chromosome 7 open reading frame 51
chr7_-_19715127 0.542 NM_001002926
TWISTNB
TWIST neighbor
chr19_+_54786723 0.540 NM_020719
PRR12
proline rich 12
chr11_+_117983515 0.530 NM_001144758
NM_001144759
PHLDB1

pleckstrin homology-like domain, family B, member 1

chr15_-_37999519 0.526


chr7_+_111908143 0.524 NM_001134468
NM_182597
C7orf53

chromosome 7 open reading frame 53

chr7_-_100262971 0.521 NM_004444
EPHB4
EPH receptor B4
chr22_+_18388633 0.518 C22orf25
chromosome 22 open reading frame 25
chr2_-_132275703 0.517 NM_214461
C2orf27B
chromosome 2 open reading frame 27B
chr6_-_41781655 0.516 TFEB
transcription factor EB
chr11_+_111666133 0.513


chr10_-_15453060 0.509 NM_001010924
FAM171A1
family with sequence similarity 171, member A1
chr16_-_47201588 0.508 NM_153029
N4BP1
NEDD4 binding protein 1
chr14_+_23700261 0.506 NM_006084
IRF9
interferon regulatory factor 9
chr8_+_21980315 0.506 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr11_-_11600118 0.505 NM_198516
GALNTL4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4
chr4_-_120767777 0.503 NM_033430
PDE5A
phosphodiesterase 5A, cGMP-specific
chr6_+_35544155 0.503 NM_007104
RPL10A
ribosomal protein L10a
chr9_+_140164359 0.501 TUBBP5
tubulin, beta pseudogene 5
chr9_-_111123017 0.492 EPB41L4B
erythrocyte membrane protein band 4.1 like 4B
chr7_-_122313646 0.485 CADPS2
Ca++-dependent secretion activator 2
chr12_+_106236281 0.485 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chr3_+_49183983 0.484 NM_173546
KLHDC8B
kelch domain containing 8B
chr5_-_146813343 0.482 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr7_-_122314017 0.473 NM_001009571
NM_001167940
NM_017954
CADPS2


Ca++-dependent secretion activator 2


chr22_+_21393107 0.470 IGLJ3
immunoglobulin lambda joining 3
chr11_-_128281309 0.467 C11orf45
chromosome 11 open reading frame 45
chr17_+_21249040 0.467 NM_001194958
KCNJ18
potassium inwardly-rectifying channel, subfamily J, member 18
chr22_-_20637212 0.466 NM_014634
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr10_+_102749222 0.466 LZTS2
leucine zipper, putative tumor suppressor 2
chr6_+_35544174 0.466 RPL10A
ribosomal protein L10a
chr1_+_64012154 0.466 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr6_-_58395610 0.466 GUSBP4
glucuronidase, beta pseudogene 4
chr6_-_41855564 0.465 NM_006653
FRS3
fibroblast growth factor receptor substrate 3
chr17_-_24253821 0.463 NM_144683
DHRS13
dehydrogenase/reductase (SDR family) member 13
chr19_-_18913017 0.462 HOMER3
homer homolog 3 (Drosophila)
chr13_-_39075304 0.457 LHFP
lipoma HMGIC fusion partner
chr19_-_18913032 0.456 NM_004838
HOMER3
homer homolog 3 (Drosophila)
chr19_-_18913011 0.453 HOMER3
homer homolog 3 (Drosophila)
chr11_-_64906683 0.453 NM_001077241
NM_182556
SLC25A45

solute carrier family 25, member 45

chr6_+_25387273 0.449 LRRC16A
leucine rich repeat containing 16A
chr7_-_91347915 0.443 NM_006980
MTERF
mitochondrial transcription termination factor
chr1_+_46418786 0.442 TSPAN1
tetraspanin 1
chr8_-_91066060 0.440 NM_002485
NBN
nibrin
chr20_+_28225511 0.440 LOC283788
FRG1B
FSHD region gene 1 pseudogene
FSHD region gene 1 family, member B
chr12_+_50104859 0.434 NM_001039960
NM_004858
SLC4A8

solute carrier family 4, sodium bicarbonate cotransporter, member 8

chr22_-_29113301 0.433 NM_001017981
RNF215
ring finger protein 215
chr17_-_19290745 0.433


chr11_+_60448487 0.433 NM_017870
NM_178031
TMEM132A

transmembrane protein 132A

chr12_+_46643592 0.432 NM_001143841
NM_001143842
NM_001143843
NM_024056
TMEM106C



transmembrane protein 106C



chr13_+_30672087 0.432 NM_194318
B3GALTL
beta 1,3-galactosyltransferase-like
chr2_-_20714303 0.431 NM_022460
HS1BP3
HCLS1 binding protein 3
chr2_-_175060001 0.431 NM_001033045
NM_152529
GPR155

G protein-coupled receptor 155

chr12_-_54869568 0.431 NM_001130420
NM_003075
NM_139067
SMARCC2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2


chr6_+_127629677 0.425 NM_030963
RNF146
ring finger protein 146
chr16_-_11798507 0.422 ZC3H7A
zinc finger CCCH-type containing 7A
chr2_-_39310176 0.420 NM_001009565
CDKL4
cyclin-dependent kinase-like 4
chr6_+_25387630 0.420 NM_001173977
NM_017640
LRRC16A

leucine rich repeat containing 16A

chr20_+_31783426 0.416 NM_032819
ZNF341
zinc finger protein 341
chr10_-_101759630 0.416 NM_015221
DNMBP
dynamin binding protein
chr5_-_70621688 0.415 SMA4
glucuronidase, beta pseudogene
chr1_-_6537139 0.414 NOL9
nucleolar protein 9
chr7_+_28305464 0.413 NM_182899
CREB5
cAMP responsive element binding protein 5
chr12_-_49949999 0.412 SMAGP
small cell adhesion glycoprotein
chr7_+_75669130 0.410 NM_001110199
SRRM3
serine/arginine repetitive matrix 3
chr9_-_129537372 0.409 NM_001085347
NM_001134430
NM_001134431
NM_130459
TOR2A



torsin family 2, member A



chr9_-_132804243 0.409 NM_001145106
FIBCD1
fibrinogen C domain containing 1
chr22_+_18388602 0.408 NM_152906
C22orf25
chromosome 22 open reading frame 25
chr19_-_18912899 0.405 HOMER3
homer homolog 3 (Drosophila)
chr1_-_17638729 0.405 RCC2
regulator of chromosome condensation 2
chr1_-_6537171 0.401 NM_024654
NOL9
nucleolar protein 9
chr9_+_126655516 0.398 NM_001045476
WDR38
WD repeat domain 38
chr3_-_48573556 0.392 PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr9_+_33614214 0.390 ANXA2P2
annexin A2 pseudogene 2
chr7_-_99517128 0.385 NM_017715
NM_032924
ZNF3

zinc finger protein 3

chr1_+_9217444 0.382 NM_004285
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr6_+_3794620 0.378 NM_012135
FAM50B
family with sequence similarity 50, member B
chr13_-_112308729 0.378


chr2_-_190892730 0.377 HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr4_-_24590867 0.376 NM_173463
CCDC149
coiled-coil domain containing 149
chr8_-_91065961 0.375 NBN
nibrin
chr10_+_6284845 0.367 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr3_+_115040369 0.366 NM_017577
GRAMD1C
GRAM domain containing 1C
chr17_-_19206475 0.365 NM_015681
B9D1
B9 protein domain 1
chr19_+_45168872 0.362 NM_006503
NM_153001
PSMC4

proteasome (prosome, macropain) 26S subunit, ATPase, 4

chr14_+_104226769 0.359 NM_001031714
NM_022489
NM_032714
INF2


inverted formin, FH2 and WH2 domain containing


chr5_-_118352122 0.358 NM_173666
DTWD2
DTW domain containing 2
chr2_+_182464713 0.357 NM_001130445
NM_006751
SSFA2

sperm specific antigen 2

chr7_-_22506320 0.356 NM_001164460
NM_207342
MGC87042

STEAP family protein MGC87042

chr9_-_111122826 0.355 NM_018424
NM_019114
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chr17_-_58877276 0.353 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr17_-_69869552 0.353 NM_001080466
BTBD17
BTB (POZ) domain containing 17
chr20_-_1395463 0.352 NSFL1C
NSFL1 (p97) cofactor (p47)
chr11_+_107384617 0.349 NM_003478
CUL5
cullin 5
chr17_-_52393364 0.345 NM_004645
COIL
coilin
chr12_+_13088412 0.344 KIAA1467
KIAA1467
chr6_-_47385470 0.340 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr19_+_47480445 0.339 NM_015125
CIC
capicua homolog (Drosophila)
chr14_-_106084085 0.339 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_-_47385605 0.336 NM_014452
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr11_+_118332217 0.335 NM_006760
UPK2
uroplakin 2
chr12_-_119187871 0.335 PXN
paxillin
chr2_-_218865451 0.335 NM_022152
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr17_+_72376022 0.333 NM_144677
MGAT5B
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr20_+_42537927 0.332 NM_001039199
NM_024331
TTPAL

tocopherol (alpha) transfer protein-like

chr8_+_43067817 0.329


chr17_-_43263859 0.322 NM_145255
NM_148887
MRPL10

mitochondrial ribosomal protein L10

chr8_+_43067805 0.321 NM_032237
SGK196
protein kinase-like protein SgK196
chr6_-_47385599 0.320 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr22_+_18388656 0.319 C22orf25
chromosome 22 open reading frame 25
chr20_+_48240867 0.318 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr1_+_9217384 0.318 H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr11_+_66841885 0.318 LOC100130987
similar to hCG1815675
chr11_+_67130898 0.316 NM_001166102
NM_007103
NDUFV1

NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa

chrX_+_11686198 0.314 NM_078628
NM_078629
MSL3

male-specific lethal 3 homolog (Drosophila)

chr12_+_121803255 0.311 NM_003677
DENR
density-regulated protein
chr10_+_73241645 0.311 NM_001171935
NM_001171936
CDH23

cadherin-related 23

chr6_-_47385604 0.310 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr9_+_696744 0.309 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chr18_+_586997 0.309 NM_014410
CLUL1
clusterin-like 1 (retinal)

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 8.51e-05 GO:0005622 intracellular
1.14 2.22e-04 GO:0044424 intracellular part
1.20 3.32e-04 GO:0005737 cytoplasm
1.23 5.05e-03 GO:0044444 cytoplasmic part
1.38 8.97e-03 GO:0043228 non-membrane-bounded organelle
1.38 8.97e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.23 1.16e-02 GO:0044446 intracellular organelle part
1.42 1.21e-02 GO:0070013 intracellular organelle lumen
1.22 2.45e-02 GO:0044422 organelle part
1.39 2.89e-02 GO:0043233 organelle lumen
1.38 3.81e-02 GO:0031974 membrane-enclosed lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.02 4.55e-03 GO:0008092 cytoskeletal protein binding
1.18 2.00e-02 GO:0005515 protein binding