Motif ID: EBF1.p2

Z-value: 2.992


Transcription factors associated with EBF1.p2:

Gene SymbolEntrez IDGene Name
EBF1 1879 early B-cell factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EBF1chr5_-_1584590060.312.4e-01Click!


Activity profile for motif EBF1.p2.

activity profile for motif EBF1.p2


Sorted Z-values histogram for motif EBF1.p2

Sorted Z-values for motif EBF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EBF1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_71095733 4.587 MYO15B
myosin XVB pseudogene
chr9_-_135140450 4.461 NM_020469
ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr9_-_135140425 4.370 ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr19_-_38408449 3.722 NM_019849
SLC7A10
solute carrier family 7, (neutral amino acid transporter, y+ system) member 10
chr17_-_10042579 3.710 NM_201433
GAS7
growth arrest-specific 7
chr11_+_61276576 2.870 NM_001127392
C11orf9
chromosome 11 open reading frame 9
chr17_+_56884560 2.637 TBX4
T-box 4
chr10_-_135021502 2.467 NM_001098483
NM_198472
C10orf125

chromosome 10 open reading frame 125

chr5_+_178300799 2.299 NM_001178089
NM_001178090
NM_182594
ZNF454


zinc finger protein 454


chr3_-_129694717 2.276 NM_032638
GATA2
GATA binding protein 2
chr4_+_42094612 2.234 NM_001080505
SHISA3
shisa homolog 3 (Xenopus laevis)
chr15_-_77024375 2.229 CTSH
cathepsin H
chr2_-_238804953 2.142 LOC151174
hypothetical LOC151174
chr8_+_104582151 2.094 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr10_-_134605978 2.080 NM_173572
C10orf93
chromosome 10 open reading frame 93
chr12_+_5023345 2.066 NM_002234
KCNA5
potassium voltage-gated channel, shaker-related subfamily, member 5
chr10_+_134901397 2.031 NM_014468
VENTX
VENT homeobox homolog (Xenopus laevis)
chr11_+_122806196 1.995 LOC100128242
hypothetical LOC100128242
chr10_+_23521464 1.931 NM_178161
PTF1A
pancreas specific transcription factor, 1a
chr3_+_32255158 1.908 NM_178868
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr13_+_112671497 1.872 MCF2L
MCF.2 cell line derived transforming sequence-like
chr22_-_35875890 1.870 NM_000878
IL2RB
interleukin 2 receptor, beta
chr3_+_127743868 1.837 CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr10_+_83625049 1.821 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr11_+_69602055 1.791 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr4_-_85638410 1.781 NM_006168
NKX6-1
NK6 homeobox 1
chrX_+_151991474 1.744 NM_001170944
NM_032882
LOC100287428
PNMA6A
paraneoplastic antigen-like protein 6A related gene
paraneoplastic antigen like 6A
chr15_-_77024408 1.740 NM_004390
CTSH
cathepsin H
chr6_-_84475211 1.710 SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr2_+_24086456 1.708 NM_001080473
MFSD2B
major facilitator superfamily domain containing 2B
chr6_-_78229838 1.666 NM_000863
HTR1B
5-hydroxytryptamine (serotonin) receptor 1B
chr3_+_32255215 1.623 CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr4_-_57216816 1.579 HOPX
HOP homeobox
chr4_+_4438883 1.577 NM_001040101
NM_014392
D4S234E

DNA segment on chromosome 4 (unique) 234 expressed sequence

chr19_+_55627971 1.560 NM_004533
MYBPC2
myosin binding protein C, fast type
chr4_-_110443247 1.547 NM_032518
NM_198721
COL25A1

collagen, type XXV, alpha 1

chr19_+_52215982 1.534 NM_002517
NPAS1
neuronal PAS domain protein 1
chr1_-_92721633 1.528 GFI1
growth factor independent 1 transcription repressor
chr14_+_104117100 1.491 NM_001008404
C14orf180
chromosome 14 open reading frame 180
chr14_+_102659464 1.483 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr6_-_167940374 1.466 C6orf123
chromosome 6 open reading frame 123
chr4_+_4439705 1.448 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr16_+_155972 1.435 NM_001003938
HBM
hemoglobin, mu
chr11_-_29995063 1.432 NM_002233
KCNA4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr3_+_214668 1.428


chr8_-_139578246 1.425 NM_015912
FAM135B
family with sequence similarity 135, member B
chr3_+_185430910 1.420 NM_138345
VWA5B2
von Willebrand factor A domain containing 5B2
chr13_+_112670757 1.412 NM_001112732
MCF2L
MCF.2 cell line derived transforming sequence-like
chr14_-_104142125 1.403 NM_207379
TMEM179
transmembrane protein 179
chr4_+_4439618 1.392 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr5_-_132194488 1.381 NM_001172700
SHROOM1
shroom family member 1
chr15_+_76889873 1.373 MORF4L1
mortality factor 4 like 1
chr5_-_1498510 1.371 NM_001044
SLC6A3
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
chr6_+_118335381 1.366 NM_001029858
SLC35F1
solute carrier family 35, member F1
chr19_-_4468715 1.365 NM_001080400
PLIN4
perilipin 4
chr19_+_1727117 1.361


chr14_-_94053933 1.361 NM_173850
SERPINA12
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chr3_+_128830656 1.356 NM_015720
PODXL2
podocalyxin-like 2
chr17_+_73638430 1.352 NM_152468
TMC8
transmembrane channel-like 8
chr17_+_77910411 1.341 NM_207459
TEX19
testis expressed 19
chr4_-_90977149 1.324 NM_001146054
NM_007308
NM_000345
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr20_-_60228665 1.322 NM_007232
HRH3
histamine receptor H3
chr16_-_2186465 1.308 NM_020764
CASKIN1
CASK interacting protein 1
chr4_+_4439750 1.281 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr11_-_100959868 1.277 NM_004621
TRPC6
transient receptor potential cation channel, subfamily C, member 6
chr16_+_57091546 1.277 NDRG4
NDRG family member 4
chr4_-_6253152 1.276 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr11_-_2248374 1.265 ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr11_-_2248757 1.264 NM_005170
ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr19_+_10242516 1.243 NM_000201
ICAM1
intercellular adhesion molecule 1
chr22_+_43442987 1.239 NM_001017528
NM_001017529
PRR5

proline rich 5 (renal)

chr19_+_10242763 1.236 ICAM1
intercellular adhesion molecule 1
chr5_-_904100 1.231 NM_024786
ZDHHC11
zinc finger, DHHC-type containing 11
chr3_+_46717826 1.225 NM_147196
TMIE
transmembrane inner ear
chr4_-_41579325 1.210


chr19_+_12810258 1.210 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr20_+_60918836 1.199 NM_001853
COL9A3
collagen, type IX, alpha 3
chr16_+_66236559 1.195 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr9_+_140037863 1.195 CACNA1B
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr13_-_52211836 1.193 LECT1
leukocyte cell derived chemotaxin 1
chr8_+_22465171 1.184 NM_005775
SORBS3
sorbin and SH3 domain containing 3
chr21_+_44530148 1.181 NM_000383
AIRE
autoimmune regulator
chr7_+_49783774 1.179 NM_198570
VWC2
von Willebrand factor C domain containing 2
chr8_+_22465368 1.172 SORBS3
sorbin and SH3 domain containing 3
chr19_-_60528480 1.160 NM_001085488
TMEM150B
transmembrane protein 150B
chr8_+_54015020 1.151 NM_005285
NPBWR1
neuropeptides B/W receptor 1
chr7_-_124192265 1.138 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr1_+_891739 1.137 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr10_-_725522 1.137 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr18_-_6404900 1.132 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr4_+_4912272 1.127 NM_002448
MSX1
msh homeobox 1
chr19_+_17723285 1.122 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr11_-_57038891 1.119 NM_001198810
SLC43A1
solute carrier family 43, member 1
chr17_-_1874927 1.119 NM_178568
RTN4RL1
reticulon 4 receptor-like 1
chr1_-_149385556 1.116 NM_001178061
NM_001178062
NM_030913
SEMA6C


sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C


chr19_-_54267690 1.111 KCNA7
potassium voltage-gated channel, shaker-related subfamily, member 7
chr11_-_31796061 1.107 NM_001127612
PAX6
paired box 6
chr14_-_93914634 1.102 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chrX_-_39921525 1.102 NM_001123383
NM_001123384
BCOR

BCL6 corepressor

chr16_-_4528739 1.100 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr16_+_85101734 1.097 FOXF1
forkhead box F1
chr18_-_42590989 1.086 NM_013305
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr2_-_233501069 1.085 NM_001114090
NGEF
neuronal guanine nucleotide exchange factor
chr3_-_49882308 1.083 NM_024046
CAMKV
CaM kinase-like vesicle-associated
chr4_+_2013517 1.083 NM_001168243
NM_001141936
C4orf48

chromosome 4 open reading frame 48

chr19_-_60369731 1.082 NM_178837
C19orf51
chromosome 19 open reading frame 51
chr2_-_241480058 1.080 NM_024861
C2orf54
chromosome 2 open reading frame 54
chr17_+_41217391 1.078 NM_001145146
NM_001145147
NM_001145148
NM_004382
CRHR1



corticotropin releasing hormone receptor 1



chr4_-_57217226 1.073 NM_001145459
NM_139211
HOPX

HOP homeobox

chr14_+_72773957 1.070 NM_173462
NDRG2
PAPLN
NDRG family member 2
papilin, proteoglycan-like sulfated glycoprotein
chr4_+_156807311 1.069 NM_000856
NM_001130682
NM_001130686
NM_001130687
NM_001130683
NM_001130685
GUCY1A3





guanylate cyclase 1, soluble, alpha 3





chr4_-_55686503 1.066 NM_002253
KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr14_-_51605461 1.065 NID2
nidogen 2 (osteonidogen)
chr17_+_41424665 1.062 MAPT
microtubule-associated protein tau
chr14_+_103674812 1.062 NM_015656
KIF26A
kinesin family member 26A
chr10_-_73518269 1.057 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr10_-_118021532 1.054 NM_145793
GFRA1
GDNF family receptor alpha 1
chr16_+_1323627 1.047 BAIAP3
BAI1-associated protein 3
chr4_+_2764510 1.046 NM_001122681
SH3BP2
SH3-domain binding protein 2
chr19_+_1236766 1.037 NM_001405
EFNA2
ephrin-A2
chr14_-_51605487 1.035 NID2
nidogen 2 (osteonidogen)
chr2_+_242364912 1.031 NM_022134
GAL3ST2
galactose-3-O-sulfotransferase 2
chr11_+_817584 1.028 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr5_+_80292313 1.028 NM_006909
RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr10_-_73518284 1.022 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr11_-_2108035 1.018 IGF2
insulin-like growth factor 2 (somatomedin A)
chr4_-_155632317 1.016 NM_001142552
NM_001142553
DCHS2

dachsous 2 (Drosophila)

chr1_-_19473021 1.010 NM_001145289
NM_201252
AKR7L

aldo-keto reductase family 7-like

chr8_-_140784416 1.010 NM_016601
KCNK9
potassium channel, subfamily K, member 9
chr10_+_133850325 1.007 NM_006426
DPYSL4
dihydropyrimidinase-like 4
chr21_+_42946719 1.003 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr11_-_117252541 0.996 FXYD6
FXYD domain containing ion transport regulator 6
chr9_-_138762725 0.993 NM_198946
LCN6
lipocalin 6
chr1_-_92722088 0.987 GFI1
growth factor independent 1 transcription repressor
chr7_-_44147436 0.986 NM_021223
MYL7
myosin, light chain 7, regulatory
chr2_+_176761552 0.984 NM_024501
HOXD1
homeobox D1
chr19_-_56018815 0.977 NM_002257
KLK1
kallikrein 1
chr5_-_141238127 0.975 NM_002587
NM_032420
PCDH1

protocadherin 1

chr7_-_71439678 0.972 CALN1
calneuron 1
chr19_-_56260135 0.970 NM_015596
KLK13
kallikrein-related peptidase 13
chr11_+_359723 0.970 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr2_+_219432789 0.966 NM_006522
WNT6
wingless-type MMTV integration site family, member 6
chr8_-_144312831 0.963 NM_002347
LY6H
lymphocyte antigen 6 complex, locus H
chr22_+_38183480 0.961 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chrX_-_102452461 0.961 NM_001168399
NM_001168400
NM_001168401
NM_032621
BEX2



brain expressed X-linked 2



chr14_-_51605515 0.960 NID2
nidogen 2 (osteonidogen)
chr22_+_43451351 0.958 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr3_-_184628548 0.957 NM_015078
MCF2L2
MCF.2 cell line derived transforming sequence-like 2
chr7_+_154943466 0.956 NM_001427
EN2
engrailed homeobox 2
chr11_+_20647692 0.955 NM_006157
NM_201551
NELL1

NEL-like 1 (chicken)

chr19_-_12891074 0.951 NM_001105578
SYCE2
synaptonemal complex central element protein 2
chr19_+_11510578 0.950 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr2_-_43919392 0.944 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr19_+_58715988 0.943 NM_018555
ZNF331
zinc finger protein 331
chr1_+_150914394 0.934 NM_178429
LCE2C
late cornified envelope 2C
chr12_-_56418295 0.931 NM_001122772
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr10_+_46413551 0.930 NM_014696
GPRIN2
G protein regulated inducer of neurite outgrowth 2
chr11_-_14950366 0.930 NM_001033952
NM_001033953
NM_001741
CALCA


calcitonin-related polypeptide alpha


chr16_+_85101605 0.929 NM_001451
FOXF1
forkhead box F1
chr14_+_91859904 0.923 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr10_-_73518315 0.922 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr5_-_132194122 0.919


chr18_+_73090913 0.916 NM_001480
GALR1
galanin receptor 1
chr2_+_96355661 0.916 NM_178495
NM_001163524
ITPRIPL1

inositol 1,4,5-triphosphate receptor interacting protein-like 1

chr14_+_69021149 0.909 NM_001161498
UPF0639
UPF0639 protein
chr4_+_2789686 0.900 NM_001145856
SH3BP2
SH3-domain binding protein 2
chr11_-_132318741 0.897 OPCML
opioid binding protein/cell adhesion molecule-like
chr4_+_156808261 0.896 NM_001130684
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr4_+_2764609 0.890 SH3BP2
SH3-domain binding protein 2
chr4_+_37569093 0.889 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr15_-_66511488 0.885 NM_001004439
ITGA11
integrin, alpha 11
chr22_+_23153529 0.884 NM_000675
ADORA2A
adenosine A2a receptor
chr5_+_3649167 0.882 NM_024337
IRX1
iroquois homeobox 1
chr5_+_80292213 0.875 RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr5_+_75414994 0.874 NM_014979
SV2C
synaptic vesicle glycoprotein 2C
chr5_+_175241449 0.873 CPLX2
complexin 2
chr3_+_48482213 0.872 NM_016381
NM_033629
TREX1

three prime repair exonuclease 1

chr21_-_36836767 0.870 NM_001146078
CLDN14
claudin 14
chr22_+_43476710 0.870 NM_181333
PRR5
proline rich 5 (renal)
chr5_+_132176921 0.866 NM_175873
ANKRD43
ankyrin repeat domain 43
chr1_-_20122638 0.865 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr1_-_26245031 0.861 NM_001004434
NM_032513
SLC30A2

solute carrier family 30 (zinc transporter), member 2

chr1_+_157408000 0.860 NM_021189
NM_001127173
CADM3

cell adhesion molecule 3

chr15_-_60244773 0.859 NM_001007595
C2CD4B
C2 calcium-dependent domain containing 4B
chr4_-_5942818 0.857 CRMP1
collapsin response mediator protein 1
chr5_+_57914658 0.855 NM_138453
RAB3C
RAB3C, member RAS oncogene family
chr14_+_105024301 0.855 NM_001311
CRIP1
cysteine-rich protein 1 (intestinal)
chr11_-_106394039 0.854 NM_000855
GUCY1A2
guanylate cyclase 1, soluble, alpha 2
chr22_-_19122107 0.853 NM_153334
NM_182895
SCARF2

scavenger receptor class F, member 2

chr10_-_88116181 0.853 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chr18_+_11741470 0.850 NM_001142339
NM_002071
GNAL

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type

chr19_-_6393004 0.845 SLC25A23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr20_+_30814048 0.843 DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr10_+_125415860 0.843 NM_153442
GPR26
G protein-coupled receptor 26
chr5_-_76970129 0.841 OTP
orthopedia homeobox
chr4_+_91035025 0.841 NM_007351
MMRN1
multimerin 1
chr7_-_150128331 0.837 NM_001101311
NM_001101312
NM_001101314
TMEM176B


transmembrane protein 176B


chr16_+_3036682 0.837 NM_022468
MMP25
matrix metallopeptidase 25
chr7_-_960785 0.832 NM_006869
ADAP1
ArfGAP with dual PH domains 1
chr13_-_50315832 0.830 NM_198989
DLEU7
deleted in lymphocytic leukemia, 7

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.21 3.62e-04 GO:0023052 signaling
1.12 3.96e-04 GO:0065007 biological regulation
1.32 2.58e-03 GO:0023051 regulation of signaling
1.71 2.58e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.20 9.18e-03 GO:0007165 signal transduction
1.11 1.45e-02 GO:0050789 regulation of biological process
1.17 1.45e-02 GO:0051716 cellular response to stimulus
1.60 1.50e-02 GO:0007268 synaptic transmission
2.22 1.79e-02 GO:0035023 regulation of Rho protein signal transduction
1.80 1.84e-02 GO:0046578 regulation of Ras protein signal transduction
1.56 1.94e-02 GO:0019226 transmission of nerve impulse
1.56 1.94e-02 GO:0035637 multicellular organismal signaling
1.11 4.03e-02 GO:0050794 regulation of cellular process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.27 2.87e-04 GO:0044459 plasma membrane part
1.09 2.18e-02 GO:0016020 membrane
1.10 4.87e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.94 1.28e-02 GO:0005085 guanyl-nucleotide exchange factor activity