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• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: EGR1..3.p2

Z-value: 2.168

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_-_809879	4.839	NM_006651	CPLX1	complexin 1
chr2_+_104838177	3.814	NM_006236	POU3F3	POU class 3 homeobox 3
chr18_+_53253775	3.108	NM_004852	ONECUT2	one cut homeobox 2
chr20_-_60074237	3.072	NM_003185	TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr1_+_41022066	2.874	NM_004700 NM_172163	KCNQ4	potassium voltage-gated channel, KQT-like subfamily, member 4
chr15_+_22644448	2.846
chr2_+_42128521	2.608	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr7_-_526005	2.432	NM_002607 NM_033023	PDGFA	platelet-derived growth factor alpha polypeptide
chr7_-_525556	2.395		PDGFA	platelet-derived growth factor alpha polypeptide
chr7_+_55922623	2.344		ZNF713	zinc finger protein 713
chr16_+_1143241	2.292	NM_001005407 NM_021098	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr2_+_10101081	2.052	NM_003597 NM_001177716	KLF11	Kruppel-like factor 11
chr3_-_185461768	2.017	NM_033259	CAMK2N2	calcium/calmodulin-dependent protein kinase II inhibitor 2
chr6_+_99389300	1.932	NM_005604	POU3F2	POU class 3 homeobox 2
chr17_+_75366524	1.846	NM_005189 NM_032647	CBX2	chromobox homolog 2
chr17_+_77582774	1.840	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr1_+_38032045	1.840	NM_001031740 NM_001113482	MANEAL	mannosidase, endo-alpha-like
chr13_-_19633182	1.838	NM_021954	GJA3	gap junction protein, alpha 3, 46kDa
chr6_+_99389318	1.814		POU3F2	POU class 3 homeobox 2
chr20_-_61933012	1.788		ZBTB46	zinc finger and BTB domain containing 46
chr4_+_77391876	1.757	NM_001136570	FAM47E	family with sequence similarity 47, member E
chr11_+_359723	1.724	NM_178537	B4GALNT4	beta-1,4-N-acetyl-galactosaminyl transferase 4
chr19_+_540849	1.676	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr3_-_49882308	1.648	NM_024046	CAMKV	CaM kinase-like vesicle-associated
chr19_+_52215982	1.632	NM_002517	NPAS1	neuronal PAS domain protein 1
chr14_-_60022487	1.608	NM_174978	C14orf39	chromosome 14 open reading frame 39
chr11_+_2422747	1.577	NM_000218	KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1
chr16_-_27982277	1.575	NM_001109763	GSG1L	GSG1-like
chr3_+_12304332	1.558	NM_005037 NM_138712	PPARG	peroxisome proliferator-activated receptor gamma
chr14_-_20636337	1.554		ZNF219	zinc finger protein 219
chr10_-_128884411	1.537	NM_001039762	FAM196A	family with sequence similarity 196, member A
chr10_-_103525646	1.529	NM_006119 NM_033163 NM_033164 NM_033165	FGF8	fibroblast growth factor 8 (androgen-induced)
chr12_+_127317900	1.522	NM_001136103	TMEM132C	transmembrane protein 132C
chr10_+_133850325	1.497	NM_006426	DPYSL4	dihydropyrimidinase-like 4
chr22_+_48951286	1.479	NM_001160300 NM_052839	PANX2	pannexin 2
chr7_+_49783774	1.457	NM_198570	VWC2	von Willebrand factor C domain containing 2
chr17_+_14145051	1.454	NM_006041	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr17_+_9489578	1.443	NM_153210	USP43	ubiquitin specific peptidase 43
chr12_+_119632213	1.442	NM_001080533	UNC119B	unc-119 homolog B (C. elegans)
chr5_-_59225377	1.441	NM_001104631	PDE4D	phosphodiesterase 4D, cAMP-specific
chr11_-_16992524	1.402	NM_175058	PLEKHA7	pleckstrin homology domain containing, family A member 7
chr19_+_1704661	1.380	NM_001080488	ONECUT3	one cut homeobox 3
chr6_+_19945578	1.362	NM_001546	ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr19_+_56506907	1.347	NM_001101372	IGLON5	IgLON family member 5
chr22_+_49459935	1.336	NM_001080420	SHANK3	SH3 and multiple ankyrin repeat domains 3
chr10_+_134893766	1.326	NM_003577	UTF1	undifferentiated embryonic cell transcription factor 1
chr10_-_64248932	1.302	NM_001136178	EGR2	early growth response 2
chr3_-_24511456	1.299		THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr7_-_44331544	1.289	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr22_+_28446288	1.287	NM_182527	CABP7	calcium binding protein 7
chr15_+_38520594	1.265	NM_014952	BAHD1	bromo adjacent homology domain containing 1
chr19_+_57492236	1.259	NM_144684	ZNF480	zinc finger protein 480
chr16_+_86193993	1.238	NM_020655	JPH3	junctophilin 3
chr4_+_152549776	1.220	NM_001109977	FAM160A1	family with sequence similarity 160, member A1
chr2_+_235525355	1.217	NM_014521	SH3BP4	SH3-domain binding protein 4
chr4_+_995395	1.211		FGFRL1	fibroblast growth factor receptor-like 1
chr3_-_159306214	1.207
chr13_-_37341859	1.194	NM_001135955 NM_001135956 NM_001135957 NM_001135958 NM_003306 NM_016179	TRPC4	transient receptor potential cation channel, subfamily C, member 4
chr14_+_101297887	1.192	NM_001161725 NM_001161726	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chr16_+_28741873	1.173		ATXN2L	ataxin 2-like
chr15_-_43267441	1.171		SHF	Src homology 2 domain containing F
chr19_+_38979502	1.165	NM_001129994 NM_001129995 NM_024076	KCTD15	potassium channel tetramerisation domain containing 15
chr2_+_171280944	1.163		SP5	Sp5 transcription factor
chr1_+_116181927	1.163		NHLH2	nescient helix loop helix 2
chr5_+_76542461	1.154	NM_001029851 NM_001029852 NM_001029853 NM_001029854 NM_003719	PDE8B	phosphodiesterase 8B
chr2_-_233501069	1.135	NM_001114090	NGEF	neuronal guanine nucleotide exchange factor
chr16_+_28741908	1.135	NM_007245 NM_145714 NM_148414 NM_148415 NM_148416	ATXN2L	ataxin 2-like
chr12_+_48641545	1.121	NM_001651	AQP5	aquaporin 5
chr3_+_53504070	1.113	NM_000720 NM_001128839 NM_001128840	CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr7_+_44110527	1.113		AEBP1	AE binding protein 1
chr3_-_159306532	1.095	NM_001163678 NM_003030 NM_006884	SHOX2	short stature homeobox 2
chr1_-_240754620	1.086	NM_152666	PLD5	phospholipase D family, member 5
chr2_-_182253457	1.082	NM_002500	NEUROD1	neurogenic differentiation 1
chrX_-_152592450	1.077		PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr4_-_111763655	1.069	NM_000325	PITX2	paired-like homeodomain 2
chr4_+_2031036	1.055	NM_178557	NAT8L	N-acetyltransferase 8-like (GCN5-related, putative)
chr3_+_148610516	1.052		ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)
chrX_-_72215949	1.047	NM_001012977	PABPC1L2A PABPC1L2B	poly(A) binding protein, cytoplasmic 1-like 2A poly(A) binding protein, cytoplasmic 1-like 2B
chrX_-_152853402	1.030	NM_003491	NAA10	N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr3_+_46898673	1.025	NM_001184744	PTH1R	parathyroid hormone 1 receptor
chr15_+_39573363	1.023	NM_002220	ITPKA	inositol 1,4,5-trisphosphate 3-kinase A
chr14_+_51850754	1.020	NM_000956	PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa
chr7_-_100331417	1.015	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr4_-_105631915	1.011	NM_025212	CXXC4	CXXC finger protein 4
chr16_+_28741861	1.007		ATXN2L	ataxin 2-like
chr16_-_2186465	1.001	NM_020764	CASKIN1	CASK interacting protein 1
chr5_+_167889123	0.996
chrX_-_132376660	0.995	NM_001448	GPC4	glypican 4
chr1_+_32992131	0.995
chr22_+_27798887	0.994	NM_001039570 NM_032045	KREMEN1	kringle containing transmembrane protein 1
chr14_-_20636909	0.992	NM_001101672	ZNF219	zinc finger protein 219
chr16_-_53520208	0.983		CRNDE	colorectal neoplasia differentially expressed (non-protein coding)
chr17_+_56831951	0.983	NM_005994	TBX2	T-box 2
chr7_-_32897934	0.982	NM_015483	KBTBD2	kelch repeat and BTB (POZ) domain containing 2
chr14_+_104402626	0.973	NM_001112726 NM_015005	KIAA0284	KIAA0284
chr5_-_45731976	0.964	NM_021072	HCN1	hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr7_+_45580704	0.945		ADCY1	adenylate cyclase 1 (brain)
chr3_+_53503626	0.943		CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chrX_-_50230329	0.939	NM_001013742	DGKK	diacylglycerol kinase, kappa
chr19_+_12810258	0.936	NM_014975	MAST1	microtubule associated serine/threonine kinase 1
chr9_-_111300350	0.935	NM_001145368 NM_002829	PTPN3	protein tyrosine phosphatase, non-receptor type 3
chr19_+_7834124	0.934		EVI5L	ecotropic viral integration site 5-like
chr2_+_176680251	0.931	NM_021192	HOXD11	homeobox D11
chr13_-_113066366	0.924	NM_024719	GRTP1	growth hormone regulated TBC protein 1
chr11_-_1549719	0.919	NM_004420	DUSP8	dual specificity phosphatase 8
chr1_-_158306570	0.918	NM_002241	KCNJ10	potassium inwardly-rectifying channel, subfamily J, member 10
chrX_+_51092407	0.910		NUDT10	nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr4_+_3264509	0.908		RGS12	regulator of G-protein signaling 12
chr2_-_200028977	0.905		SATB2	SATB homeobox 2
chr12_+_50271283	0.902	NM_014191	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit
chrX_-_152591936	0.899	NM_001135740	PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr19_-_1518875	0.897	NM_001174118 NM_203304	MEX3D	mex-3 homolog D (C. elegans)
chr18_-_68685789	0.895	NM_138966	NETO1	neuropilin (NRP) and tolloid (TLL)-like 1
chr7_-_27206249	0.893	NM_000522	HOXA13	homeobox A13
chr17_+_45993338	0.887	NM_018896 NM_198376 NM_198377 NM_198378 NM_198379 NM_198380 NM_198382 NM_198383 NM_198384 NM_198385 NM_198386 NM_198387 NM_198388 NM_198396 NM_198397	CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit
chr19_+_659766	0.886	NM_001040134 NM_002579	PALM	paralemmin
chr1_-_31154023	0.882	NM_014654	SDC3	syndecan 3
chr16_+_1604641	0.880	NM_020825	CRAMP1L	Crm, cramped-like (Drosophila)
chr1_+_60053050	0.872	NM_015888	HOOK1	hook homolog 1 (Drosophila)
chr6_+_84799969	0.872	NM_138409	MRAP2	melanocortin 2 receptor accessory protein 2
chr5_-_148014282	0.869		HTR4	5-hydroxytryptamine (serotonin) receptor 4
chr9_+_139892049	0.866	NM_000718	CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit
chr7_-_525336	0.865		PDGFA	platelet-derived growth factor alpha polypeptide
chr14_-_20636568	0.864	NM_016423	ZNF219	zinc finger protein 219
chr19_+_40325993	0.863	NM_022006	FXYD7	FXYD domain containing ion transport regulator 7
chrX_-_132377087	0.862		GPC4	glypican 4
chr7_+_24290331	0.858	NM_000905	NPY	neuropeptide Y
chr1_-_40027097	0.858		BMP8B	bone morphogenetic protein 8b
chrX_+_23262905	0.852	NM_173495	PTCHD1	patched domain containing 1
chr5_+_149526533	0.852	NM_001804	CDX1	caudal type homeobox 1
chr6_-_94185780	0.852	NM_004440	EPHA7	EPH receptor A7
chr4_-_41848874	0.852		BEND4	BEN domain containing 4
chr22_+_47350781	0.826	NM_015381	FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr7_+_45580606	0.825	NM_021116	ADCY1	adenylate cyclase 1 (brain)
chr10_-_132999798	0.823		TCERG1L	transcription elongation regulator 1-like
chr5_-_9599157	0.822	NM_003966	SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr22_+_20101661	0.814	NM_015094	HIC2	hypermethylated in cancer 2
chr13_-_26232777	0.811	NM_005288	GPR12	G protein-coupled receptor 12
chr19_+_38485583	0.804		LOC80054	hypothetical LOC80054
chr8_-_72919161	0.803		MSC	musculin
chr13_+_24844084	0.799	NM_016529	ATP8A2	ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr20_-_47532585	0.799	NM_004975	KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1
chr3_-_53054999	0.797		SFMBT1	Scm-like with four mbt domains 1
chr22_+_38720881	0.796	NM_138435	FAM83F	family with sequence similarity 83, member F
chr1_-_6162669	0.787	NM_015557	CHD5	chromodomain helicase DNA binding protein 5
chr20_-_538909	0.782	NM_004609	TCF15	transcription factor 15 (basic helix-loop-helix)
chr20_+_20296744	0.781	NM_002196	INSM1	insulinoma-associated 1
chr16_-_19803606	0.776	NM_016235	GPRC5B	G protein-coupled receptor, family C, group 5, member B
chr15_-_43267139	0.768		SHF	Src homology 2 domain containing F
chr5_-_45731588	0.768		HCN1	hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr11_+_56984702	0.764	NM_178570	RTN4RL2	reticulon 4 receptor-like 2
chr12_+_52689062	0.764	NM_022658	HOXC8	homeobox C8
chr16_-_695719	0.759	NM_153350	FBXL16	F-box and leucine-rich repeat protein 16
chr11_-_94603857	0.759	NM_144665	SESN3	sestrin 3
chr19_-_13478037	0.756	NM_000068 NM_001127221 NM_001127222 NM_001174080 NM_023035	CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr16_+_1323627	0.752		BAIAP3	BAI1-associated protein 3
chr4_-_111763356	0.750		PITX2	paired-like homeodomain 2
chrX_+_17303270	0.748		NHS	Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr2_-_96899396	0.745	NM_017789	SEMA4C	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr8_+_16929116	0.744	NM_181723	EFHA2	EF-hand domain family, member A2
chr9_-_137938778	0.744	NM_015447	CAMSAP1	calmodulin regulated spectrin-associated protein 1
chr1_-_21850874	0.742	NM_001145658	RAP1GAP	RAP1 GTPase activating protein
chr6_-_46566969	0.740		RCAN2	regulator of calcineurin 2
chr5_+_3649167	0.738	NM_024337	IRX1	iroquois homeobox 1
chr8_-_144313053	0.738		LY6H	lymphocyte antigen 6 complex, locus H
chr14_+_20636935	0.738	NM_001146683	C14orf176	chromosome 14 open reading frame 176
chr17_+_56832492	0.735		TBX2	T-box 2
chr16_+_1143738	0.734		CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr17_+_56832255	0.734		TBX2	T-box 2
chr13_-_113066202	0.730		GRTP1	growth hormone regulated TBC protein 1
chr19_-_60383280	0.729	NM_003180	SYT5	synaptotagmin V
chrX_-_152592958	0.726	NM_001039582	PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr9_-_23811477	0.723	NM_001171197	ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr1_-_23623713	0.723	NM_003196	TCEA3	transcription elongation factor A (SII), 3
chr20_-_30636535	0.721		LOC284804	hypothetical protein LOC284804
chr17_+_26839143	0.714		RAB11FIP4	RAB11 family interacting protein 4 (class II)
chr8_-_144583718	0.713	NM_201589	MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr15_-_27901828	0.712	NM_003257 NM_175610	TJP1	tight junction protein 1 (zona occludens 1)
chr7_-_32897888	0.711		KBTBD2	kelch repeat and BTB (POZ) domain containing 2
chr9_+_70509925	0.706	NM_003558	PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr7_+_6622051	0.704	NM_017560	ZNF853	zinc finger protein 853
chr11_-_70641267	0.704		SHANK2	SH3 and multiple ankyrin repeat domains 2
chr4_-_41579325	0.703
chr8_-_26778832	0.702	NM_000680 NM_033302 NM_033303 NM_033304	ADRA1A	adrenergic, alpha-1A-, receptor
chr7_+_44110470	0.701	NM_001129	AEBP1	AE binding protein 1
chr5_+_79366746	0.695	NM_003248	THBS4	thrombospondin 4
chr1_-_99242765	0.694	NM_001010861 NM_001037317	LPPR5	lipid phosphate phosphatase-related protein type 5
chr13_+_111769913	0.693	NM_005986	SOX1	SRY (sex determining region Y)-box 1
chr9_+_128416542	0.692	NM_001174146 NM_001174147 NM_002316	LMX1B	LIM homeobox transcription factor 1, beta
chr17_-_75427644	0.692	NM_003655	CBX4	chromobox homolog 4
chr8_-_111056099	0.691	NM_014379	KCNV1	potassium channel, subfamily V, member 1
chr14_-_62581656	0.689	NM_139318 NM_172375	KCNH5	potassium voltage-gated channel, subfamily H (eag-related), member 5
chr19_+_45799060	0.689	NM_001042545	LTBP4	latent transforming growth factor beta binding protein 4
chr3_-_48675321	0.673	NM_001407	CELSR3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr2_-_70871239	0.670	NM_001004311	FIGLA	folliculogenesis specific basic helix-loop-helix
chr11_-_18769703	0.668	NM_001039970 NM_006906 NM_032781	PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr5_-_148013908	0.663	NM_000870	HTR4	5-hydroxytryptamine (serotonin) receptor 4
chr19_+_47480445	0.658	NM_015125	CIC	capicua homolog (Drosophila)
chr5_-_107034484	0.656	NM_001962	EFNA5	ephrin-A5
chr11_-_118740069	0.656	NM_171997	USP2	ubiquitin specific peptidase 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.75	1.78e-36	GO:0007399	nervous system development
1.36	2.39e-26	GO:0032502	developmental process
1.38	2.94e-26	GO:0007275	multicellular organismal development
1.43	4.86e-26	GO:0048731	system development
1.40	3.65e-25	GO:0048856	anatomical structure development
1.81	1.39e-24	GO:0022008	neurogenesis
1.83	3.97e-24	GO:0048699	generation of neurons
1.21	4.31e-22	GO:0050794	regulation of cellular process
1.20	6.98e-21	GO:0050789	regulation of biological process
1.57	8.32e-21	GO:0009653	anatomical structure morphogenesis
1.74	8.64e-21	GO:0048468	cell development
1.85	6.43e-20	GO:0030182	neuron differentiation
1.18	7.94e-20	GO:0065007	biological regulation
1.46	2.46e-19	GO:0030154	cell differentiation
1.44	1.59e-18	GO:0048869	cellular developmental process
1.92	2.79e-16	GO:0000904	cell morphogenesis involved in differentiation
1.88	2.96e-15	GO:0007417	central nervous system development
1.90	3.16e-15	GO:0031175	neuron projection development
1.92	2.34e-14	GO:0048812	neuron projection morphogenesis
1.95	2.39e-14	GO:0007409	axonogenesis
1.76	2.80e-14	GO:0032989	cellular component morphogenesis
1.86	3.12e-14	GO:0048858	cell projection morphogenesis
1.80	3.29e-14	GO:0048666	neuron development
1.86	3.45e-14	GO:0032990	cell part morphogenesis
1.92	6.11e-14	GO:0048667	cell morphogenesis involved in neuron differentiation
1.75	7.06e-14	GO:0030030	cell projection organization
1.77	9.21e-14	GO:0009887	organ morphogenesis
1.77	1.34e-13	GO:0000902	cell morphogenesis
1.38	1.90e-13	GO:0048523	negative regulation of cellular process
1.10	2.10e-13	GO:0009987	cellular process
1.35	5.40e-13	GO:0048519	negative regulation of biological process
1.43	5.61e-13	GO:0023051	regulation of signaling
1.55	7.61e-13	GO:0010646	regulation of cell communication
1.27	6.41e-12	GO:0060255	regulation of macromolecule metabolic process
1.32	9.70e-12	GO:0010468	regulation of gene expression
1.65	2.75e-11	GO:0009790	embryo development
2.05	4.06e-11	GO:0035295	tube development
1.55	1.41e-10	GO:0050793	regulation of developmental process
1.33	2.04e-10	GO:0051252	regulation of RNA metabolic process
1.36	2.54e-10	GO:0048513	organ development
1.92	2.66e-10	GO:0007411	axon guidance
1.24	2.83e-10	GO:0023052	signaling
1.51	6.76e-10	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.23	7.00e-10	GO:0019222	regulation of metabolic process
1.24	9.15e-10	GO:0080090	regulation of primary metabolic process
1.66	1.37e-09	GO:0010629	negative regulation of gene expression
1.18	1.54e-09	GO:0032501	multicellular organismal process
1.24	1.59e-09	GO:0031323	regulation of cellular metabolic process
1.43	1.74e-09	GO:0051239	regulation of multicellular organismal process
2.32	4.79e-09	GO:0045165	cell fate commitment
1.31	5.08e-09	GO:0006355	regulation of transcription, DNA-dependent
1.29	5.52e-09	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.83	6.51e-09	GO:0007420	brain development
1.27	6.88e-09	GO:0048518	positive regulation of biological process
1.28	7.17e-09	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.56	1.12e-08	GO:2000026	regulation of multicellular organismal development
1.77	1.76e-08	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.28	2.58e-08	GO:0048522	positive regulation of cellular process
1.26	4.72e-08	GO:0051171	regulation of nitrogen compound metabolic process
2.13	4.86e-08	GO:0035239	tube morphogenesis
2.22	7.12e-08	GO:0048562	embryonic organ morphogenesis
1.27	7.61e-08	GO:0010556	regulation of macromolecule biosynthetic process
1.80	8.75e-08	GO:0007389	pattern specification process
1.64	1.08e-07	GO:0045892	negative regulation of transcription, DNA-dependent
1.56	1.32e-07	GO:0010628	positive regulation of gene expression
1.37	1.40e-07	GO:0009966	regulation of signal transduction
1.57	1.51e-07	GO:0007167	enzyme linked receptor protein signaling pathway
1.62	1.60e-07	GO:0051253	negative regulation of RNA metabolic process
1.76	1.67e-07	GO:0048598	embryonic morphogenesis
1.55	2.10e-07	GO:0031327	negative regulation of cellular biosynthetic process
1.55	2.45e-07	GO:0045595	regulation of cell differentiation
1.26	2.61e-07	GO:0031326	regulation of cellular biosynthetic process
2.39	3.52e-07	GO:0043583	ear development
1.57	4.43e-07	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.47	4.77e-07	GO:0009888	tissue development
1.25	5.10e-07	GO:0009889	regulation of biosynthetic process
1.56	5.19e-07	GO:0045893	positive regulation of transcription, DNA-dependent
1.53	8.14e-07	GO:0009890	negative regulation of biosynthetic process
2.17	8.59e-07	GO:0060562	epithelial tube morphogenesis
1.56	9.61e-07	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.46	1.07e-06	GO:0040011	locomotion
1.92	1.07e-06	GO:0003002	regionalization
1.83	1.48e-06	GO:0051960	regulation of nervous system development
1.52	2.03e-06	GO:0051254	positive regulation of RNA metabolic process
1.92	2.12e-06	GO:0002009	morphogenesis of an epithelium
1.77	2.39e-06	GO:0060284	regulation of cell development
1.61	2.74e-06	GO:0019226	transmission of nerve impulse
1.61	2.74e-06	GO:0035637	multicellular organismal signaling
1.54	2.83e-06	GO:0051172	negative regulation of nitrogen compound metabolic process
1.20	2.87e-06	GO:0051179	localization
1.76	2.98e-06	GO:0001501	skeletal system development
1.87	3.38e-06	GO:0050767	regulation of neurogenesis
1.41	3.54e-06	GO:0007154	cell communication
1.52	3.74e-06	GO:0010558	negative regulation of macromolecule biosynthetic process
2.07	5.71e-06	GO:0006813	potassium ion transport
2.42	5.77e-06	GO:0048839	inner ear development
2.69	7.25e-06	GO:0042472	inner ear morphogenesis
1.79	8.73e-06	GO:0007423	sensory organ development
2.53	9.08e-06	GO:0042471	ear morphogenesis
1.76	9.23e-06	GO:0048729	tissue morphogenesis
1.20	9.69e-06	GO:0007165	signal transduction
1.86	9.89e-06	GO:0048568	embryonic organ development
1.62	1.03e-05	GO:0023057	negative regulation of signaling
1.62	1.23e-05	GO:0010648	negative regulation of cell communication
1.46	1.51e-05	GO:0007267	cell-cell signaling
1.94	1.64e-05	GO:0032582	negative regulation of gene-specific transcription
1.67	1.68e-05	GO:0009792	embryo development ending in birth or egg hatching
1.36	2.10e-05	GO:0010604	positive regulation of macromolecule metabolic process
1.60	2.43e-05	GO:0051094	positive regulation of developmental process
3.13	2.51e-05	GO:0001656	metanephros development
1.63	2.92e-05	GO:0009968	negative regulation of signal transduction
1.45	2.95e-05	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28	3.05e-05	GO:0007166	cell surface receptor linked signaling pathway
1.42	3.23e-05	GO:0006351	transcription, DNA-dependent
2.21	3.24e-05	GO:0060541	respiratory system development
2.29	4.63e-05	GO:0030323	respiratory tube development
1.39	5.08e-05	GO:0009892	negative regulation of metabolic process
1.44	5.10e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
1.64	6.74e-05	GO:0043009	chordate embryonic development
1.16	7.34e-05	GO:0044260	cellular macromolecule metabolic process
1.38	7.41e-05	GO:0032879	regulation of localization
1.40	7.50e-05	GO:0031324	negative regulation of cellular metabolic process
1.56	7.90e-05	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.54	8.04e-05	GO:0006935	chemotaxis
1.54	8.04e-05	GO:0042330	taxis
1.44	8.80e-05	GO:0010557	positive regulation of macromolecule biosynthetic process
1.40	8.91e-05	GO:0010605	negative regulation of macromolecule metabolic process
1.54	9.35e-05	GO:0048585	negative regulation of response to stimulus
1.63	9.87e-05	GO:0060429	epithelium development
1.58	1.02e-04	GO:0007268	synaptic transmission
1.87	1.02e-04	GO:0045664	regulation of neuron differentiation
1.38	1.45e-04	GO:0042127	regulation of cell proliferation
2.26	1.69e-04	GO:0030324	lung development
1.97	1.86e-04	GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter
1.16	1.87e-04	GO:0051716	cellular response to stimulus
1.57	2.26e-04	GO:0032583	regulation of gene-specific transcription
1.52	2.27e-04	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.77	2.56e-04	GO:0007507	heart development
1.20	2.74e-04	GO:0051234	establishment of localization
1.26	3.05e-04	GO:0006464	protein modification process
1.32	3.37e-04	GO:0009893	positive regulation of metabolic process
2.21	3.56e-04	GO:0048754	branching morphogenesis of a tube
1.67	3.73e-04	GO:0022603	regulation of anatomical structure morphogenesis
1.85	3.82e-04	GO:0048732	gland development
1.25	3.92e-04	GO:0043412	macromolecule modification
2.40	5.70e-04	GO:2000027	regulation of organ morphogenesis
1.21	5.86e-04	GO:0071842	cellular component organization at cellular level
1.22	6.11e-04	GO:0042221	response to chemical stimulus
1.51	6.48e-04	GO:0030001	metal ion transport
1.53	6.64e-04	GO:0048646	anatomical structure formation involved in morphogenesis
1.32	9.30e-04	GO:0031325	positive regulation of cellular metabolic process
1.61	1.04e-03	GO:0044057	regulation of system process
1.83	1.06e-03	GO:0051051	negative regulation of transport
2.00	1.06e-03	GO:0048705	skeletal system morphogenesis
2.04	1.13e-03	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.01	1.20e-03	GO:0001763	morphogenesis of a branching structure
1.51	1.36e-03	GO:0072358	cardiovascular system development
1.51	1.36e-03	GO:0072359	circulatory system development
1.19	1.44e-03	GO:0006810	transport
1.37	1.50e-03	GO:0031328	positive regulation of cellular biosynthetic process
1.37	1.53e-03	GO:0009891	positive regulation of biosynthetic process
1.34	1.97e-03	GO:0009605	response to external stimulus
1.23	3.41e-03	GO:0048583	regulation of response to stimulus
1.85	3.42e-03	GO:0009952	anterior/posterior pattern formation
1.82	3.55e-03	GO:0030900	forebrain development
1.89	3.68e-03	GO:0001655	urogenital system development
1.19	3.77e-03	GO:0071841	cellular component organization or biogenesis at cellular level
1.16	4.03e-03	GO:0016043	cellular component organization
2.19	5.66e-03	GO:0055123	digestive system development
1.45	5.95e-03	GO:0023056	positive regulation of signaling
2.23	6.69e-03	GO:0016331	morphogenesis of embryonic epithelium
1.32	6.82e-03	GO:0032774	RNA biosynthetic process
2.14	7.30e-03	GO:0060828	regulation of canonical Wnt receptor signaling pathway
1.56	9.94e-03	GO:0045597	positive regulation of cell differentiation
1.42	1.03e-02	GO:0006812	cation transport
1.35	1.05e-02	GO:0051128	regulation of cellular component organization
1.37	1.08e-02	GO:0006468	protein phosphorylation
1.68	1.08e-02	GO:0032868	response to insulin stimulus
1.53	1.17e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.98	1.26e-02	GO:0072001	renal system development
3.04	1.29e-02	GO:0072006	nephron development
1.31	1.36e-02	GO:0006793	phosphorus metabolic process
1.31	1.36e-02	GO:0006796	phosphate metabolic process
1.60	1.43e-02	GO:0061061	muscle structure development
1.99	1.44e-02	GO:0061138	morphogenesis of a branching epithelium
2.45	1.51e-02	GO:0090090	negative regulation of canonical Wnt receptor signaling pathway
1.59	1.73e-02	GO:0040012	regulation of locomotion
1.43	1.89e-02	GO:0010647	positive regulation of cell communication
1.82	2.17e-02	GO:0046883	regulation of hormone secretion
1.71	2.32e-02	GO:0043408	regulation of MAPKKK cascade
1.54	2.48e-02	GO:0015672	monovalent inorganic cation transport
1.99	2.49e-02	GO:0043410	positive regulation of MAPKKK cascade
1.12	2.58e-02	GO:0043170	macromolecule metabolic process
2.21	2.58e-02	GO:0001657	ureteric bud development
1.15	2.69e-02	GO:0071840	cellular component organization or biogenesis
1.43	2.71e-02	GO:0009967	positive regulation of signal transduction
1.36	2.78e-02	GO:0051049	regulation of transport
1.96	2.90e-02	GO:0001822	kidney development
3.42	2.94e-02	GO:0072073	kidney epithelium development
2.26	3.03e-02	GO:0032409	regulation of transporter activity
2.29	3.24e-02	GO:0001838	embryonic epithelial tube formation
1.34	3.78e-02	GO:0016192	vesicle-mediated transport
1.56	3.84e-02	GO:0051270	regulation of cellular component movement
2.50	3.86e-02	GO:0048663	neuron fate commitment
2.50	3.86e-02	GO:0060021	palate development
3.53	4.13e-02	GO:0060993	kidney morphogenesis
1.82	4.30e-02	GO:0016055	Wnt receptor signaling pathway
2.22	4.41e-02	GO:0035148	tube formation
2.25	4.77e-02	GO:0072175	epithelial tube formation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.96	8.53e-16	GO:0045202	synapse
1.76	7.27e-15	GO:0030054	cell junction
2.06	1.18e-13	GO:0044456	synapse part
1.09	7.04e-12	GO:0005622	intracellular
1.09	1.36e-11	GO:0044424	intracellular part
1.31	1.63e-10	GO:0044459	plasma membrane part
1.10	1.70e-09	GO:0043226	organelle
1.10	6.26e-09	GO:0043229	intracellular organelle
1.10	8.72e-08	GO:0043227	membrane-bounded organelle
1.10	1.91e-07	GO:0043231	intracellular membrane-bounded organelle
1.64	1.32e-06	GO:0043005	neuron projection
1.10	2.97e-06	GO:0005737	cytoplasm
2.00	3.34e-06	GO:0030136	clathrin-coated vesicle
2.47	3.35e-06	GO:0014069	postsynaptic density
1.14	4.42e-06	GO:0005634	nucleus
2.38	5.06e-06	GO:0008021	synaptic vesicle
1.04	1.27e-05	GO:0005623	cell
1.04	1.66e-05	GO:0044464	cell part
1.43	2.23e-05	GO:0016023	cytoplasmic membrane-bounded vesicle
1.42	2.35e-05	GO:0031988	membrane-bounded vesicle
1.78	7.84e-05	GO:0034702	ion channel complex
1.39	8.97e-05	GO:0031982	vesicle
2.78	9.85e-05	GO:0030672	synaptic vesicle membrane
1.96	1.37e-04	GO:0034703	cation channel complex
1.70	1.86e-04	GO:0005667	transcription factor complex
1.38	2.62e-04	GO:0031410	cytoplasmic vesicle
1.86	6.57e-04	GO:0045211	postsynaptic membrane
1.74	7.14e-04	GO:0030135	coated vesicle
1.75	7.85e-04	GO:0030425	dendrite
2.13	9.47e-04	GO:0008076	voltage-gated potassium channel complex
2.13	9.47e-04	GO:0034705	potassium channel complex
1.78	4.59e-03	GO:0005912	adherens junction
1.73	5.87e-03	GO:0070161	anchoring junction
1.30	7.84e-03	GO:0042995	cell projection
1.20	9.44e-03	GO:0031981	nuclear lumen
2.00	1.22e-02	GO:0030665	clathrin coated vesicle membrane
1.12	1.43e-02	GO:0005886	plasma membrane
1.12	1.63e-02	GO:0071944	cell periphery
1.95	1.89e-02	GO:0016585	chromatin remodeling complex
1.60	3.18e-02	GO:0005911	cell-cell junction
2.44	3.58e-02	GO:0000118	histone deacetylase complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.83	2.49e-20	GO:0043565	sequence-specific DNA binding
1.67	2.67e-20	GO:0030528	transcription regulator activity
1.19	8.46e-20	GO:0005515	protein binding
1.64	2.80e-18	GO:0001071	nucleic acid binding transcription factor activity
1.64	2.80e-18	GO:0003700	sequence-specific DNA binding transcription factor activity
1.09	9.57e-15	GO:0005488	binding
1.87	9.04e-10	GO:0016563	transcription activator activity
2.06	1.20e-08	GO:0010843	promoter binding
2.03	1.76e-08	GO:0000975	regulatory region DNA binding
2.03	1.76e-08	GO:0001067	regulatory region nucleic acid binding
2.03	1.76e-08	GO:0044212	transcription regulatory region DNA binding
1.28	2.82e-08	GO:0003677	DNA binding
2.45	1.46e-07	GO:0005249	voltage-gated potassium channel activity
2.18	1.50e-07	GO:0022843	voltage-gated cation channel activity
2.18	1.64e-06	GO:0005267	potassium channel activity
1.90	1.18e-05	GO:0005244	voltage-gated ion channel activity
1.90	1.18e-05	GO:0022832	voltage-gated channel activity
1.74	1.35e-05	GO:0005261	cation channel activity
1.18	3.09e-05	GO:0003676	nucleic acid binding
1.59	3.93e-05	GO:0005216	ion channel activity
1.66	5.16e-05	GO:0022836	gated channel activity
1.58	5.50e-05	GO:0022838	substrate-specific channel activity
1.54	1.93e-04	GO:0015267	channel activity
1.64	1.94e-04	GO:0008134	transcription factor binding
1.54	2.24e-04	GO:0022803	passive transmembrane transporter activity
1.48	1.85e-03	GO:0019904	protein domain specific binding
1.34	3.59e-03	GO:0016301	kinase activity
2.10	6.10e-03	GO:0019199	transmembrane receptor protein kinase activity
1.38	7.59e-03	GO:0004672	protein kinase activity
1.34	8.05e-03	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.57	9.42e-03	GO:0032403	protein complex binding
2.02	1.57e-02	GO:0003705	sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.28	1.62e-02	GO:0005102	receptor binding
1.57	2.02e-02	GO:0003702	RNA polymerase II transcription factor activity
1.50	2.67e-02	GO:0016564	transcription repressor activity
1.94	2.85e-02	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
1.63	3.74e-02	GO:0003682	chromatin binding
1.36	4.12e-02	GO:0008324	cation transmembrane transporter activity
1.31	4.51e-02	GO:0015075	ion transmembrane transporter activity

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