Motif ID: EHF.p2

Z-value: 3.404


Transcription factors associated with EHF.p2:

Gene SymbolEntrez IDGene Name
EHF 26298 ets homologous factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EHFchr11_+_34599227-0.234.0e-01Click!


Activity profile for motif EHF.p2.

activity profile for motif EHF.p2


Sorted Z-values histogram for motif EHF.p2

Sorted Z-values for motif EHF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EHF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_19636918 4.822 NM_001012991
 C16orf88
chromosome 16 open reading frame 88
chr20_+_16658608 4.809 NM_003092
NM_198220
 SNRPB2

small nuclear ribonucleoprotein polypeptide B

chr14_+_34831294 3.832 NM_002791
 PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr14_+_34831355 3.800 PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr6_+_111409933 3.487 NM_032194
 RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr20_+_33750645 3.286 NM_080748
 ROMO1
reactive oxygen species modulator 1
chr17_-_44377094 3.280 NM_007241
 SNF8
SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
chr14_+_34521945 3.151 SRP54
signal recognition particle 54kDa
chr2_-_27147995 3.135 NM_001134693
 OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr14_-_38709161 3.119 NM_001079537
NM_177452
 TRAPPC6B

trafficking protein particle complex 6B

chr1_-_234834410 3.090 NM_018072
 HEATR1
HEAT repeat containing 1
chr14_+_23771464 3.061 NM_001002000
NM_001002001
 GMPR2

guanosine monophosphate reductase 2

chr16_+_8799170 3.060 NM_000303
 PMM2
phosphomannomutase 2
chr14_-_21049204 3.049 NM_019852
 METTL3
methyltransferase like 3
chr14_+_34521854 3.048 NM_001146282
NM_003136
 SRP54

signal recognition particle 54kDa

chr20_+_43478120 2.988 NM_001184728
NM_001184729
NM_001184730
NM_015937
 PIGT



phosphatidylinositol glycan anchor biosynthesis, class T



chr9_-_124733599 2.951 NM_020924
 ZBTB26
zinc finger and BTB domain containing 26
chr20_-_33750457 2.944 NM_001198989
NM_021100
 NFS1

NFS1 nitrogen fixation 1 homolog (S. cerevisiae)

chr2_+_220170804 2.936 NM_052902
 STK11IP
serine/threonine kinase 11 interacting protein
chr15_+_32304477 2.884 NM_016454
 TMEM85
transmembrane protein 85

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 120 entries
enrichment   p-value GO term description
2.80 2.92e-07 GO:0071826 ribonucleoprotein complex subunit organization
2.76 2.73e-06 GO:0022618 ribonucleoprotein complex assembly
2.68 1.35e-02 GO:0050434 positive regulation of viral transcription
2.59 1.52e-04 GO:0006354 transcription elongation, DNA-dependent
2.58 4.21e-03 GO:0006368 transcription elongation from RNA polymerase II promoter
2.51 5.01e-03 GO:0071158 positive regulation of cell cycle arrest
2.50 1.03e-03 GO:0006353 transcription termination, DNA-dependent
2.49 3.53e-02 GO:0046782 regulation of viral transcription
2.45 5.79e-03 GO:0072594 establishment of protein localization to organelle
2.44 2.27e-02 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.44 2.27e-02 GO:0072395 signal transduction involved in cell cycle checkpoint
2.44 2.27e-02 GO:0072401 signal transduction involved in DNA integrity checkpoint
2.44 2.27e-02 GO:0072404 signal transduction involved in G1/S transition checkpoint
2.44 2.27e-02 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
2.44 2.27e-02 GO:0072422 signal transduction involved in DNA damage checkpoint
2.44 2.27e-02 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.44 2.27e-02 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
2.39 8.70e-11 GO:0022613 ribonucleoprotein complex biogenesis
2.37 4.11e-03 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.37 4.11e-03 GO:0071779 G1/S transition checkpoint

Gene overrepresentation in compartment category:

Showing 1 to 20 of 49 entries
enrichment   p-value GO term description
3.08 5.34e-03 GO:0030532 small nuclear ribonucleoprotein complex
2.79 4.34e-02 GO:0030660 Golgi-associated vesicle membrane
2.64 5.44e-06 GO:0071013 catalytic step 2 spliceosome
2.60 4.57e-02 GO:0030120 vesicle coat
2.43 1.54e-02 GO:0005798 Golgi-associated vesicle
2.34 1.35e-02 GO:0015934 large ribosomal subunit
2.33 3.99e-07 GO:0005681 spliceosomal complex
2.27 2.52e-02 GO:0000502 proteasome complex
2.20 4.34e-05 GO:0016607 nuclear speck
2.17 2.11e-02 GO:0022626 cytosolic ribosome
2.15 2.78e-02 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
2.04 6.75e-19 GO:0030529 ribonucleoprotein complex
1.99 1.94e-05 GO:0005840 ribosome
1.93 2.85e-03 GO:0000151 ubiquitin ligase complex
1.87 3.97e-05 GO:0016604 nuclear body
1.68 1.15e-07 GO:0005730 nucleolus
1.68 4.95e-02 GO:0005819 spindle
1.59 3.50e-02 GO:0010008 endosome membrane
1.57 7.89e-23 GO:0031981 nuclear lumen
1.57 4.55e-02 GO:0044440 endosomal part

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
2.28 2.71e-03 GO:0008135 translation factor activity, nucleic acid binding
2.05 1.15e-04 GO:0003735 structural constituent of ribosome
1.99 2.30e-02 GO:0008026 ATP-dependent helicase activity
1.99 2.30e-02 GO:0070035 purine NTP-dependent helicase activity
1.87 7.59e-05 GO:0004842 ubiquitin-protein ligase activity
1.84 7.75e-05 GO:0019787 small conjugating protein ligase activity
1.75 2.17e-04 GO:0016881 acid-amino acid ligase activity
1.69 7.44e-14 GO:0003723 RNA binding
1.66 1.24e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.46 1.72e-02 GO:0016874 ligase activity
1.32 1.06e-14 GO:0003676 nucleic acid binding
1.23 1.85e-03 GO:0008270 zinc ion binding
1.20 8.00e-03 GO:0003677 DNA binding
1.19 2.07e-02 GO:0000166 nucleotide binding
1.18 4.61e-15 GO:0005515 protein binding
1.09 1.71e-10 GO:0005488 binding