Motif ID: ELF1,2,4.p2

Z-value: 2.658


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELF2chr4_-_1402249140.844.4e-05Click!
ELF1chr13_-_404914050.514.4e-02Click!
ELF4chrX_-_1290723330.322.3e-01Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_42527760 4.537 NM_033502
 TRERF1
transcriptional regulating factor 1
chr20_+_3138055 3.799 NM_033453
NM_181493
 ITPA

inosine triphosphatase (nucleoside triphosphate pyrophosphatase)

chr14_+_22845851 3.545 NM_004050
 BCL2L2-PABPN1
BCL2L2
BCL2L2-PABPN1 read-through transcript
BCL2-like 2
chr2_-_73817935 3.481 NM_016058
 TPRKB
TP53RK binding protein
chr2_+_198026470 3.347 NM_025147
 COQ10B
coenzyme Q10 homolog B (S. cerevisiae)
chr2_-_45691887 3.177 NM_018079
 SRBD1
S1 RNA binding domain 1
chr2_-_201461945 3.046 NM_032472
NM_130906
 PPIL3

peptidylprolyl isomerase (cyclophilin)-like 3

chr2_-_207738858 2.875 NM_003709
 KLF7
Kruppel-like factor 7 (ubiquitous)
chr17_+_43328514 2.752 NM_003110
 SP2
Sp2 transcription factor
chr20_+_60191455 2.752 NM_015666
 GTPBP5
GTP binding protein 5 (putative)
chr20_+_33750645 2.727 NM_080748
 ROMO1
reactive oxygen species modulator 1
chr10_-_51041156 2.717 NM_003631
 AGAP8
LOC728407
PARG
ArfGAP with GTPase domain, ankyrin repeat and PH domain 8
poly(ADP-ribose) glycohydrolase pseudogene
poly (ADP-ribose) glycohydrolase
chr2_-_54051290 2.618 NM_014614
 PSME4
proteasome (prosome, macropain) activator subunit 4
chr20_+_16658608 2.616 NM_003092
NM_198220
 SNRPB2

small nuclear ribonucleoprotein polypeptide B

chr20_+_18496068 2.598 LOC388789
hypothetical LOC388789
chr16_+_8799170 2.574 NM_000303
 PMM2
phosphomannomutase 2
chr6_-_119137923 2.561 NM_001178035
 C6orf204
chromosome 6 open reading frame 204
chr12_-_119116848 2.527 NM_006836
 GCN1L1
GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
chr2_-_27147995 2.523 NM_001134693
 OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr20_-_33750457 2.499 NM_001198989
NM_021100
 NFS1

NFS1 nitrogen fixation 1 homolog (S. cerevisiae)


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 165 entries
enrichment   p-value GO term description
2.75 3.77e-02 GO:0006362 transcription elongation from RNA polymerase I promoter
2.58 4.26e-02 GO:0006360 transcription from RNA polymerase I promoter
2.58 4.26e-02 GO:0006361 transcription initiation from RNA polymerase I promoter
2.05 9.64e-04 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
2.04 2.35e-06 GO:0006414 translational elongation
2.03 5.55e-04 GO:0006353 transcription termination, DNA-dependent
2.02 1.28e-04 GO:0019080 viral genome expression
2.02 1.28e-04 GO:0019083 viral transcription
2.02 4.97e-03 GO:0071158 positive regulation of cell cycle arrest
2.01 3.81e-04 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.01 3.81e-04 GO:0071779 G1/S transition checkpoint
2.00 2.61e-04 GO:2000045 regulation of G1/S transition of mitotic cell cycle
1.99 1.78e-04 GO:0006415 translational termination
1.94 4.08e-02 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
1.94 4.08e-02 GO:0072395 signal transduction involved in cell cycle checkpoint
1.94 4.08e-02 GO:0072401 signal transduction involved in DNA integrity checkpoint
1.94 4.08e-02 GO:0072404 signal transduction involved in G1/S transition checkpoint
1.94 4.08e-02 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
1.94 4.08e-02 GO:0072422 signal transduction involved in DNA damage checkpoint
1.94 4.08e-02 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint

Gene overrepresentation in compartment category:

Showing 1 to 20 of 46 entries
enrichment   p-value GO term description
2.15 4.47e-02 GO:0022627 cytosolic small ribosomal subunit
1.95 4.98e-04 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
1.90 1.04e-03 GO:0071013 catalytic step 2 spliceosome
1.84 8.88e-03 GO:0022626 cytosolic ribosome
1.81 1.10e-05 GO:0005681 spliceosomal complex
1.74 2.24e-02 GO:0030027 lamellipodium
1.73 1.04e-06 GO:0005840 ribosome
1.72 1.51e-04 GO:0000793 condensed chromosome
1.72 2.09e-02 GO:0001726 ruffle
1.71 2.63e-04 GO:0000151 ubiquitin ligase complex
1.71 1.00e-03 GO:0016607 nuclear speck
1.70 1.20e-18 GO:0030529 ribonucleoprotein complex
1.62 1.33e-05 GO:0016604 nuclear body
1.62 2.72e-04 GO:0031252 cell leading edge
1.58 2.16e-03 GO:0044454 nuclear chromosome part
1.52 9.52e-10 GO:0005730 nucleolus
1.51 2.90e-03 GO:0000228 nuclear chromosome
1.50 1.74e-02 GO:0005819 spindle
1.44 1.50e-28 GO:0031981 nuclear lumen
1.44 9.49e-20 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
1.94 4.61e-04 GO:0008135 translation factor activity, nucleic acid binding
1.91 3.24e-03 GO:0047485 protein N-terminus binding
1.77 1.69e-05 GO:0003735 structural constituent of ribosome
1.62 2.75e-05 GO:0003713 transcription coactivator activity
1.58 1.95e-02 GO:0003714 transcription corepressor activity
1.54 1.47e-07 GO:0003712 transcription cofactor activity
1.54 1.90e-07 GO:0000988 protein binding transcription factor activity
1.54 1.90e-07 GO:0000989 transcription factor binding transcription factor activity
1.52 9.86e-17 GO:0003723 RNA binding
1.25 1.45e-02 GO:0019899 enzyme binding
1.23 2.47e-16 GO:0003676 nucleic acid binding
1.17 1.65e-28 GO:0005515 protein binding
1.15 2.52e-03 GO:0003677 DNA binding
1.13 3.52e-02 GO:0000166 nucleotide binding
1.08 3.66e-16 GO:0005488 binding