Motif ID: ELF1,2,4.p2

Z-value: 2.658


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELF2chr4_-_1402249140.844.4e-05Click!
ELF1chr13_-_404914050.514.4e-02Click!
ELF4chrX_-_1290723330.322.3e-01Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_42527760 4.537 NM_033502
TRERF1
transcriptional regulating factor 1
chr20_+_3138055 3.799 NM_033453
NM_181493
ITPA

inosine triphosphatase (nucleoside triphosphate pyrophosphatase)

chr14_+_22845851 3.545 NM_004050
BCL2L2-PABPN1
BCL2L2
BCL2L2-PABPN1 read-through transcript
BCL2-like 2
chr2_-_73817935 3.481 NM_016058
TPRKB
TP53RK binding protein
chr2_+_198026470 3.347 NM_025147
COQ10B
coenzyme Q10 homolog B (S. cerevisiae)
chr2_-_45691887 3.177 NM_018079
SRBD1
S1 RNA binding domain 1
chr2_-_201461945 3.046 NM_032472
NM_130906
PPIL3

peptidylprolyl isomerase (cyclophilin)-like 3

chr2_-_207738858 2.875 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chr17_+_43328514 2.752 NM_003110
SP2
Sp2 transcription factor
chr20_+_60191455 2.752 NM_015666
GTPBP5
GTP binding protein 5 (putative)
chr20_+_33750645 2.727 NM_080748
ROMO1
reactive oxygen species modulator 1
chr10_-_51041156 2.717 NM_003631
AGAP8
LOC728407
PARG
ArfGAP with GTPase domain, ankyrin repeat and PH domain 8
poly(ADP-ribose) glycohydrolase pseudogene
poly (ADP-ribose) glycohydrolase
chr2_-_54051290 2.618 NM_014614
PSME4
proteasome (prosome, macropain) activator subunit 4
chr20_+_16658608 2.616 NM_003092
NM_198220
SNRPB2

small nuclear ribonucleoprotein polypeptide B

chr20_+_18496068 2.598 LOC388789
hypothetical LOC388789
chr16_+_8799170 2.574 NM_000303
PMM2
phosphomannomutase 2
chr6_-_119137923 2.561 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr12_-_119116848 2.527 NM_006836
GCN1L1
GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
chr2_-_27147995 2.523 NM_001134693
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr20_-_33750457 2.499 NM_001198989
NM_021100
NFS1

NFS1 nitrogen fixation 1 homolog (S. cerevisiae)

chr16_+_2593351 2.445 LOC652276
hypothetical LOC652276
chr2_-_55349818 2.377 NM_001005369
MTIF2
mitochondrial translational initiation factor 2
chr16_-_8798973 2.370 NM_015421
TMEM186
transmembrane protein 186
chr20_-_49008445 2.365 NM_003859
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr10_-_51293220 2.348 NM_006327
TIMM23
TIMM23B
translocase of inner mitochondrial membrane 23 homolog (yeast)
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr17_+_42355492 2.333 GOSR2
golgi SNAP receptor complex member 2
chr1_+_39229474 2.275 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr16_-_11852862 2.259 NM_015659
RSL1D1
ribosomal L1 domain containing 1
chr1_-_28842103 2.232 NM_001135218
NM_005644
TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chr17_-_39447817 2.221 NM_032376
TMEM101
transmembrane protein 101
chr17_+_70520339 2.160 NM_001545
ICT1
immature colon carcinoma transcript 1
chr14_+_23982017 2.160


chr20_-_33198721 2.117 NM_001145025
NM_018217
EDEM2

ER degradation enhancer, mannosidase alpha-like 2

chr16_-_19636918 2.105 NM_001012991
C16orf88
chromosome 16 open reading frame 88
chr14_+_34831294 2.097 NM_002791
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr14_+_34831355 2.083 PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr2_+_201462294 2.059 NM_001136039
NM_001142355
NM_021824
NIF3L1


NIF3 NGG1 interacting factor 3-like 1 (S. pombe)


chr16_+_48865521 2.021 ADCY7
adenylate cyclase 7
chr14_-_21049204 1.993 NM_019852
METTL3
methyltransferase like 3
chr2_-_37752731 1.993 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr4_+_109761170 1.975 NM_000995
NM_033625
RPL34

ribosomal protein L34

chr1_-_224993498 1.971 NM_002221
ITPKB
inositol 1,4,5-trisphosphate 3-kinase B
chr2_+_113058470 1.960 NM_032309
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr16_+_68938264 1.952 NM_018332
DDX19A
DEAD (Asp-Glu-Ala-As) box polypeptide 19A
chr17_-_44377094 1.921 NM_007241
SNF8
SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
chr15_+_32304477 1.897 NM_016454
TMEM85
transmembrane protein 85
chr14_-_22634134 1.881 ACIN1
apoptotic chromatin condensation inducer 1
chr12_+_12829807 1.875 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr20_-_2592777 1.865 NM_006899
NM_174855
NM_174856
IDH3B


isocitrate dehydrogenase 3 (NAD+) beta


chr17_+_64922420 1.839 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr2_-_55349851 1.824 NM_002453
MTIF2
mitochondrial translational initiation factor 2
chr6_-_169395972 1.823 NM_003247
THBS2
thrombospondin 2
chr2_+_113058642 1.822 CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr1_+_26358097 1.821 NM_024869
GRRP1
glycine/arginine rich protein 1
chr14_-_23981493 1.811 NM_020195
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr6_-_167491305 1.809 NM_005299
GPR31
G protein-coupled receptor 31
chr2_+_48521411 1.793 NM_001135629
NM_001193475
NM_152994
KLRAQ1


KLRAQ motif containing 1


chr20_-_33198555 1.791 EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr4_-_153820535 1.771 NM_152680
TMEM154
transmembrane protein 154
chr20_+_29598848 1.770 HM13
histocompatibility (minor) 13
chr10_-_89567863 1.765 NM_032810
ATAD1
ATPase family, AAA domain containing 1
chr20_+_49008754 1.758 NM_014484
MOCS3
molybdenum cofactor synthesis 3
chr20_+_58064360 1.756 NM_173644
C20orf197
chromosome 20 open reading frame 197
chr14_+_73423260 1.752 NM_021188
ZNF410
zinc finger protein 410
chr14_+_23937766 1.743 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr14_+_23771464 1.736 NM_001002000
NM_001002001
GMPR2

guanosine monophosphate reductase 2

chr20_-_5879036 1.732 NM_015939
TRMT6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr6_-_169395847 1.729 THBS2
thrombospondin 2
chr12_+_70519753 1.728 NM_001146213
NM_001146214
NM_022771
TBC1D15


TBC1 domain family, member 15


chr14_-_29466562 1.687 NM_002742
PRKD1
protein kinase D1
chr6_+_26646548 1.687 NM_006353
HMGN4
high mobility group nucleosomal binding domain 4
chr2_+_183651531 1.685 NM_001142314
NM_080876
DUSP19

dual specificity phosphatase 19

chr6_-_30818198 1.677 NM_005803
FLOT1
flotillin 1
chr2_+_220170804 1.664 NM_052902
STK11IP
serine/threonine kinase 11 interacting protein
chr1_+_42896634 1.648 NM_006347
PPIH
peptidylprolyl isomerase H (cyclophilin H)
chr21_+_42807052 1.648 SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr12_+_99118692 1.647 NM_022496
ACTR6
ARP6 actin-related protein 6 homolog (yeast)
chr1_-_111308017 1.646 NM_001006945
NM_018372
C1orf103

chromosome 1 open reading frame 103

chr11_-_117628211 1.640 NM_198275
MPZL3
myelin protein zero-like 3
chr2_-_74553285 1.638 NM_053050
MRPL53
mitochondrial ribosomal protein L53
chr6_-_28327980 1.627 NM_019110
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr3_-_130600931 1.624 RPL32P3
ribosomal protein L32 pseudogene 3
chr3_-_172660545 1.621 NM_001161560
NM_001161561
NM_001161562
NM_001161563
NM_001161564
NM_001161565
NM_001161566
NM_015028
TNIK







TRAF2 and NCK interacting kinase







chr6_+_139136349 1.593 NM_015439
CCDC28A
coiled-coil domain containing 28A
chr11_-_58102169 1.593 NM_001143995
LPXN
leupaxin
chr3_+_120495906 1.591 NM_020754
ARHGAP31
Rho GTPase activating protein 31
chr7_-_44496703 1.590 NM_015332
NUDCD3
NudC domain containing 3
chr16_-_15095590 1.584 NM_018427
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr12_+_67366989 1.575 NM_020401
NUP107
nucleoporin 107kDa
chr2_-_1905508 1.574 MYT1L
myelin transcription factor 1-like
chr17_-_38229790 1.574 NM_003766
BECN1
beclin 1, autophagy related
chr2_-_53867488 1.573 NM_016115
NM_145863
ASB3

ankyrin repeat and SOCS box containing 3

chr1_-_23376860 1.568 LUZP1
leucine zipper protein 1
chr6_+_143813472 1.552 NM_003630
PEX3
peroxisomal biogenesis factor 3
chr8_+_30133354 1.546 NM_006571
DCTN6
dynactin 6
chr1_-_220829704 1.543 NM_005681
NM_139352
TAF1A

TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa

chr20_+_43478120 1.542 NM_001184728
NM_001184729
NM_001184730
NM_015937
PIGT



phosphatidylinositol glycan anchor biosynthesis, class T



chr17_-_71174816 1.542 NM_004259
NM_001003715
NM_001003716
RECQL5


RecQ protein-like 5


chr14_+_23008742 1.539 NGDN
neuroguidin, EIF4E binding protein
chr12_+_118590039 1.534 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr1_+_22224571 1.533 HSPC157
hypothetical LOC29092
chr10_-_18980512 1.516 NM_182543
NSUN6
NOP2/Sun domain family, member 6
chr6_+_111409933 1.509 NM_032194
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr15_-_72952648 1.506 NM_005697
SCAMP2
secretory carrier membrane protein 2
chr2_+_176842368 1.504 NM_006554
MTX2
metaxin 2
chr8_+_59486376 1.503 NM_001077619
UBXN2B
UBX domain protein 2B
chr19_-_51909416 1.500 NM_001079882
PRKD2
protein kinase D2
chr1_+_232575850 1.486 NM_001012985
C1orf31
chromosome 1 open reading frame 31
chr6_-_27548438 1.481 NM_007149
ZNF184
zinc finger protein 184
chr2_+_149119029 1.479 NM_015630
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr6_+_30142910 1.464 NM_021959
PPP1R11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr1_+_144149794 1.463 NM_006472
TXNIP
thioredoxin interacting protein
chr20_-_34005619 1.461 SCAND1
SCAN domain containing 1
chr6_-_46997579 1.459 NM_001098518
GPR116
G protein-coupled receptor 116
chr3_+_30623376 1.458 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr14_+_74418345 1.455 NM_001933
DLST
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr14_+_23008723 1.446 NM_001042635
NM_015514
NGDN

neuroguidin, EIF4E binding protein

chr2_+_65308332 1.437 NM_001005386
NM_005722
ACTR2

ARP2 actin-related protein 2 homolog (yeast)

chr10_+_129735796 1.436 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr2_+_32244406 1.435 NM_001193513
NM_001193514
NM_001193515
NM_017964
SLC30A6



solute carrier family 30 (zinc transporter), member 6



chr11_-_17055763 1.417 NM_001017
RPS13
ribosomal protein S13
chr8_-_28403652 1.416 NM_172366
FBXO16
ZNF395
F-box protein 16
zinc finger protein 395
chr5_-_112658200 1.412 MCC
mutated in colorectal cancers
chr2_+_65517316 1.409 FLJ16124
FLJ16124 protein
chr2_+_122124034 1.408 LOC254128
hypothetical LOC254128
chr6_+_144206165 1.406 NM_032860
LTV1
LTV1 homolog (S. cerevisiae)
chr20_-_44751208 1.402 TP53RK
TP53 regulating kinase
chr3_+_3056307 1.400 NM_175612
CNTN4
contactin 4
chr6_-_34501769 1.398 NM_001014
RPS10
ribosomal protein S10
chr2_+_69974581 1.397 NM_006857
SNRNP27
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr2_-_152740387 1.391 NM_005843
STAM2
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr16_+_24648446 1.388 NM_014494
TNRC6A
trinucleotide repeat containing 6A
chr18_-_70415788 1.387 LOC400657
hypothetical LOC400657
chr2_-_20053256 1.386 NM_001006657
NM_020779
WDR35

WD repeat domain 35

chr17_-_53784494 1.384 NM_003168
SUPT4H1
suppressor of Ty 4 homolog 1 (S. cerevisiae)
chr6_+_144206202 1.365 LTV1
LTV1 homolog (S. cerevisiae)
chr1_-_203867402 1.355 ELK4
ELK4, ETS-domain protein (SRF accessory protein 1)
chr14_-_23781607 1.354 NM_001099274
NM_012461
TINF2

TERF1 (TRF1)-interacting nuclear factor 2

chr19_+_60838170 1.351


chr2_+_96790298 1.345 NM_020184
CNNM4
cyclin M4
chr14_-_23781328 1.344 TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr20_-_13567529 1.343 NM_017714
TASP1
taspase, threonine aspartase, 1
chr6_+_133177403 1.342 RPS12
ribosomal protein S12
chr2_-_174538675 1.340 NM_001172712
NM_003111
SP3

Sp3 transcription factor

chr2_-_177836773 1.331 NM_001145412
NM_001145413
NFE2L2

nuclear factor (erythroid-derived 2)-like 2

chr19_-_425875 1.330 NM_182577
ODF3L2
outer dense fiber of sperm tails 3-like 2
chr4_-_39316856 1.327 NM_174921
C4orf34
chromosome 4 open reading frame 34
chr17_-_44010543 1.324 NM_024015
HOXB4
homeobox B4
chr9_-_124715392 1.323 NM_006626
ZBTB6
zinc finger and BTB domain containing 6
chr3_+_144203061 1.320 NM_001080415
U2SURP
U2 snRNP-associated SURP domain containing
chr20_+_21231921 1.317 NM_012255
XRN2
5'-3' exoribonuclease 2
chr7_+_141084591 1.315 NM_003143
SSBP1
single-stranded DNA binding protein 1
chr17_+_42355482 1.315 NM_001012511
NM_004287
NM_054022
GOSR2


golgi SNAP receptor complex member 2


chr6_+_28301031 1.311 NM_006299
ZNF193
zinc finger protein 193
chr2_+_53867571 1.307 NM_001127397
NM_001127398
NM_015701
ERLEC1


endoplasmic reticulum lectin 1


chr17_+_34162525 1.303 NM_002795
PSMB3
proteasome (prosome, macropain) subunit, beta type, 3
chr7_+_102775309 1.299 NM_002803
PSMC2
proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr2_-_88707978 1.294 NM_004836
EIF2AK3
eukaryotic translation initiation factor 2-alpha kinase 3
chr8_-_57149588 1.286 NM_001023
NM_001146227
RPS20

ribosomal protein S20

chr20_-_10362755 1.280 NM_170784
MKKS
McKusick-Kaufman syndrome
chr17_-_53950191 1.274 NM_004687
MTMR4
myotubularin related protein 4
chr17_-_26257341 1.266 NM_024683
C17orf42
chromosome 17 open reading frame 42
chr16_-_3601580 1.263 NM_032444
SLX4
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr20_-_34005799 1.260 NM_016558
NM_033630
SCAND1

SCAN domain containing 1

chr6_+_149109841 1.255 NM_005715
UST
uronyl-2-sulfotransferase
chr18_+_31806585 1.254 NM_031446
C18orf21
chromosome 18 open reading frame 21
chr6_-_170735593 1.248 NM_002598
NM_144781
PDCD2

programmed cell death 2

chr20_-_472335 1.231 NM_001895
NM_177559
NM_177560
CSNK2A1


casein kinase 2, alpha 1 polypeptide


chr17_+_54642152 1.230 NM_018149
C17orf71
chromosome 17 open reading frame 71
chr17_+_35046843 1.224 NM_001165937
NM_001165938
NM_006804
STARD3


StAR-related lipid transfer (START) domain containing 3


chr2_+_230495439 1.218 NM_174899
FBXO36
F-box protein 36
chr12_-_64810768 1.218 NM_032338
LLPH
LLP homolog, long-term synaptic facilitation (Aplysia)
chr2_+_27740254 1.212 SLC4A1AP
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr3_+_180548173 1.211 NM_033540
MFN1
mitofusin 1
chr2_+_239000395 1.210 ASB1
ankyrin repeat and SOCS box containing 1
chr14_-_74249492 1.208 NM_001039479
KIAA0317
KIAA0317
chr14_-_38971370 1.208 NM_203301
FBXO33
F-box protein 33
chr6_+_33530297 1.207 NM_152735
ZBTB9
zinc finger and BTB domain containing 9
chr20_-_57040700 1.205 NM_006886
NM_001001977
ATP5E

ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit

chr10_+_70609986 1.202 NM_003171
SUPV3L1
suppressor of var1, 3-like 1 (S. cerevisiae)
chr2_+_27739841 1.200 NM_018158
SLC4A1AP
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr7_+_143683365 1.199 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr5_-_159778621 1.199 NM_006425
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr18_+_3252110 1.193 NM_033546
MYL12B
myosin, light chain 12B, regulatory
chr1_+_45822246 1.189 NM_001195193
NM_002482
NM_152298
NASP


nuclear autoantigenic sperm protein (histone-binding)


chr2_-_175255717 1.183 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr20_+_30161173 1.175 TM9SF4
transmembrane 9 superfamily protein member 4
chr1_+_45926433 1.174 NM_016486
TMEM69
transmembrane protein 69
chr17_+_38178999 1.173 VPS25
vacuolar protein sorting 25 homolog (S. cerevisiae)
chr11_+_8660913 1.172 RPL27A
ribosomal protein L27a
chr2_-_230494862 1.172 NM_004238
TRIP12
thyroid hormone receptor interactor 12
chr7_-_27158726 1.168


chr20_+_5879297 1.163 NM_032485
NM_182802
MCM8

minichromosome maintenance complex component 8

chr20_+_47862782 1.163 SLC9A8
solute carrier family 9 (sodium/hydrogen exchanger), member 8
chr4_+_152240182 1.161 NM_001006
RPS3A
ribosomal protein S3A
chr11_-_77026406 1.149 NM_001293
CLNS1A
chloride channel, nucleotide-sensitive, 1A
chr20_+_23279372 1.149 NM_013248
NXT1
NTF2-like export factor 1
chr14_-_22127954 1.147 NM_001344
DAD1
defender against cell death 1
chr6_+_36961617 1.146 NM_152734
C6orf89
chromosome 6 open reading frame 89
chr3_-_130362563 1.143 NM_020701
ISY1
ISY1 splicing factor homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.31 8.55e-41 GO:0044260 cellular macromolecule metabolic process
1.25 1.67e-31 GO:0043170 macromolecule metabolic process
1.41 3.43e-29 GO:0090304 nucleic acid metabolic process
1.20 2.79e-28 GO:0044237 cellular metabolic process
1.35 1.65e-27 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.43 3.95e-26 GO:0010467 gene expression
1.43 1.44e-23 GO:0016070 RNA metabolic process
1.18 5.84e-22 GO:0044238 primary metabolic process
1.16 5.26e-21 GO:0008152 metabolic process
1.40 2.72e-20 GO:0009059 macromolecule biosynthetic process
1.27 4.84e-20 GO:0006807 nitrogen compound metabolic process
1.27 6.43e-20 GO:0034641 cellular nitrogen compound metabolic process
1.40 2.54e-19 GO:0034645 cellular macromolecule biosynthetic process
1.31 3.35e-19 GO:0044267 cellular protein metabolic process
1.23 5.65e-16 GO:0071840 cellular component organization or biogenesis
1.27 3.38e-15 GO:0071841 cellular component organization or biogenesis at cellular level
1.63 4.70e-14 GO:0016071 mRNA metabolic process
1.22 7.19e-14 GO:0016043 cellular component organization
1.58 6.87e-13 GO:0000278 mitotic cell cycle
1.80 7.65e-13 GO:0006412 translation
1.26 1.02e-12 GO:0044249 cellular biosynthetic process
1.25 1.13e-12 GO:0071842 cellular component organization at cellular level
1.60 1.57e-12 GO:0044265 cellular macromolecule catabolic process
1.56 1.61e-12 GO:0009057 macromolecule catabolic process
1.33 3.23e-12 GO:0006996 organelle organization
1.25 4.56e-12 GO:0009058 biosynthetic process
1.22 1.07e-11 GO:0019538 protein metabolic process
1.41 1.25e-11 GO:0007049 cell cycle
1.07 3.68e-11 GO:0009987 cellular process
1.66 1.19e-10 GO:0006397 mRNA processing
1.50 1.56e-10 GO:0006396 RNA processing
1.51 1.60e-10 GO:0051726 regulation of cell cycle
1.43 6.76e-10 GO:0022402 cell cycle process
1.54 1.27e-09 GO:0006974 response to DNA damage stimulus
1.46 2.15e-09 GO:0022403 cell cycle phase
1.38 3.52e-09 GO:0032774 RNA biosynthetic process
1.62 3.44e-08 GO:0010564 regulation of cell cycle process
1.18 4.04e-08 GO:0060255 regulation of macromolecule metabolic process
1.56 6.66e-08 GO:0016032 viral reproduction
1.30 6.88e-08 GO:0033036 macromolecule localization
1.76 7.64e-08 GO:0071156 regulation of cell cycle arrest
1.65 8.39e-08 GO:0008380 RNA splicing
1.32 1.01e-07 GO:0044248 cellular catabolic process
1.39 1.64e-07 GO:0046907 intracellular transport
1.76 1.77e-07 GO:0000075 cell cycle checkpoint
1.37 3.58e-07 GO:0033554 cellular response to stress
1.62 3.82e-07 GO:0051325 interphase
1.57 4.68e-07 GO:0030163 protein catabolic process
1.61 9.48e-07 GO:0051329 interphase of mitotic cell cycle
1.59 1.53e-06 GO:0043632 modification-dependent macromolecule catabolic process
1.57 2.04e-06 GO:0044257 cellular protein catabolic process
2.04 2.35e-06 GO:0006414 translational elongation
1.57 2.49e-06 GO:0070647 protein modification by small protein conjugation or removal
1.58 3.44e-06 GO:0006511 ubiquitin-dependent protein catabolic process
1.57 3.97e-06 GO:0019941 modification-dependent protein catabolic process
1.56 7.69e-06 GO:0051603 proteolysis involved in cellular protein catabolic process
1.15 1.14e-05 GO:0080090 regulation of primary metabolic process
1.57 1.24e-05 GO:0048285 organelle fission
1.15 1.24e-05 GO:0031323 regulation of cellular metabolic process
1.88 1.27e-05 GO:0007093 mitotic cell cycle checkpoint
1.30 1.50e-05 GO:0008104 protein localization
1.19 1.69e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.33 2.08e-05 GO:0043933 macromolecular complex subunit organization
1.27 2.45e-05 GO:0051641 cellular localization
1.70 2.62e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.70 2.62e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
1.42 2.96e-05 GO:0070727 cellular macromolecule localization
1.27 3.01e-05 GO:0044085 cellular component biogenesis
1.18 3.92e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.92 4.06e-05 GO:0032984 macromolecular complex disassembly
1.92 4.06e-05 GO:0034623 cellular macromolecular complex disassembly
1.55 4.06e-05 GO:0000087 M phase of mitotic cell cycle
1.24 4.54e-05 GO:0009056 catabolic process
1.42 5.12e-05 GO:0034613 cellular protein localization
1.39 5.61e-05 GO:0006259 DNA metabolic process
1.67 5.70e-05 GO:0000375 RNA splicing, via transesterification reactions
1.32 6.60e-05 GO:0006351 transcription, DNA-dependent
1.17 6.74e-05 GO:0010468 regulation of gene expression
1.13 7.87e-05 GO:0019222 regulation of metabolic process
1.55 8.97e-05 GO:0000280 nuclear division
1.55 8.97e-05 GO:0007067 mitosis
1.35 1.06e-04 GO:0006915 apoptosis
1.21 1.16e-04 GO:0006464 protein modification process
1.31 1.19e-04 GO:0045184 establishment of protein localization
1.65 1.19e-04 GO:0071843 cellular component biogenesis at cellular level
2.02 1.28e-04 GO:0019080 viral genome expression
2.02 1.28e-04 GO:0019083 viral transcription
1.47 1.32e-04 GO:0006886 intracellular protein transport
1.31 1.42e-04 GO:0015031 protein transport
1.99 1.78e-04 GO:0006415 translational termination
1.34 1.98e-04 GO:0012501 programmed cell death
1.67 1.99e-04 GO:0022411 cellular component disassembly
1.67 1.99e-04 GO:0071845 cellular component disassembly at cellular level
1.41 2.04e-04 GO:0034621 cellular macromolecular complex subunit organization
1.30 2.45e-04 GO:0008219 cell death
1.56 2.48e-04 GO:0016567 protein ubiquitination
2.00 2.61e-04 GO:2000045 regulation of G1/S transition of mitotic cell cycle
1.26 2.75e-04 GO:0051649 establishment of localization in cell
1.37 3.13e-04 GO:0071822 protein complex subunit organization
1.61 3.22e-04 GO:0033365 protein localization to organelle
1.64 3.35e-04 GO:0022613 ribonucleoprotein complex biogenesis
1.52 3.60e-04 GO:0006366 transcription from RNA polymerase II promoter
1.19 3.62e-04 GO:0043412 macromolecule modification
2.01 3.81e-04 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.01 3.81e-04 GO:0071779 G1/S transition checkpoint
1.30 4.24e-04 GO:0016265 death
1.54 4.99e-04 GO:0007346 regulation of mitotic cell cycle
2.03 5.55e-04 GO:0006353 transcription termination, DNA-dependent
1.52 7.10e-04 GO:0032446 protein modification by small protein conjugation
1.16 9.41e-04 GO:0048522 positive regulation of cellular process
2.05 9.64e-04 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
1.60 9.71e-04 GO:0006605 protein targeting
1.87 1.27e-03 GO:0043241 protein complex disassembly
1.87 1.27e-03 GO:0043624 cellular protein complex disassembly
1.37 1.27e-03 GO:0010942 positive regulation of cell death
1.68 1.28e-03 GO:0010498 proteasomal protein catabolic process
1.68 1.28e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.38 1.47e-03 GO:0043065 positive regulation of apoptosis
1.37 1.48e-03 GO:0043068 positive regulation of programmed cell death
1.91 1.84e-03 GO:0030330 DNA damage response, signal transduction by p53 class mediator
1.62 2.10e-03 GO:0006260 DNA replication
1.24 3.21e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.78 3.43e-03 GO:0051320 S phase
1.44 3.50e-03 GO:0051301 cell division
1.86 3.64e-03 GO:0006352 transcription initiation, DNA-dependent
1.43 3.79e-03 GO:0016568 chromatin modification
2.02 4.97e-03 GO:0071158 positive regulation of cell cycle arrest
1.14 5.02e-03 GO:0031326 regulation of cellular biosynthetic process
1.93 5.05e-03 GO:0006354 transcription elongation, DNA-dependent
1.78 5.22e-03 GO:0000077 DNA damage checkpoint
1.69 5.36e-03 GO:0019058 viral infectious cycle
1.14 6.65e-03 GO:0009889 regulation of biosynthetic process
1.76 7.62e-03 GO:0042770 signal transduction in response to DNA damage
1.23 7.98e-03 GO:0051246 regulation of protein metabolic process
1.14 8.28e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.66 9.32e-03 GO:0000082 G1/S transition of mitotic cell cycle
1.24 9.63e-03 GO:0032268 regulation of cellular protein metabolic process
1.15 9.69e-03 GO:0051252 regulation of RNA metabolic process
1.87 1.02e-02 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.73 1.03e-02 GO:0031570 DNA integrity checkpoint
1.21 1.09e-02 GO:0009893 positive regulation of metabolic process
1.74 1.10e-02 GO:0000084 S phase of mitotic cell cycle
1.31 1.46e-02 GO:0051276 chromosome organization
1.61 1.49e-02 GO:0022415 viral reproductive process
1.69 1.53e-02 GO:0042254 ribosome biogenesis
1.22 1.57e-02 GO:0031325 positive regulation of cellular metabolic process
1.23 2.19e-02 GO:0022607 cellular component assembly
1.25 2.24e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.27 2.89e-02 GO:0016192 vesicle-mediated transport
2.75 3.77e-02 GO:0006362 transcription elongation from RNA polymerase I promoter
1.13 3.82e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15 3.88e-02 GO:0006355 regulation of transcription, DNA-dependent
1.07 3.89e-02 GO:0050789 regulation of biological process
1.94 4.08e-02 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
1.94 4.08e-02 GO:0072395 signal transduction involved in cell cycle checkpoint
1.94 4.08e-02 GO:0072401 signal transduction involved in DNA integrity checkpoint
1.94 4.08e-02 GO:0072404 signal transduction involved in G1/S transition checkpoint
1.94 4.08e-02 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
1.94 4.08e-02 GO:0072422 signal transduction involved in DNA damage checkpoint
1.94 4.08e-02 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
1.94 4.08e-02 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
1.13 4.14e-02 GO:0048518 positive regulation of biological process
2.58 4.26e-02 GO:0006360 transcription from RNA polymerase I promoter
2.58 4.26e-02 GO:0006361 transcription initiation from RNA polymerase I promoter
1.35 4.33e-02 GO:0000279 M phase

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 9.75e-54 GO:0044424 intracellular part
1.13 5.24e-52 GO:0005622 intracellular
1.17 6.86e-49 GO:0043229 intracellular organelle
1.17 1.49e-48 GO:0043226 organelle
1.18 1.43e-47 GO:0043231 intracellular membrane-bounded organelle
1.18 3.19e-47 GO:0043227 membrane-bounded organelle
1.26 5.25e-41 GO:0005634 nucleus
1.41 1.15e-33 GO:0031974 membrane-enclosed lumen
1.41 4.62e-33 GO:0043233 organelle lumen
1.41 5.02e-32 GO:0070013 intracellular organelle lumen
1.41 4.18e-31 GO:0044428 nuclear part
1.44 1.50e-28 GO:0031981 nuclear lumen
1.20 3.87e-24 GO:0044446 intracellular organelle part
1.20 1.07e-23 GO:0044422 organelle part
1.13 6.14e-20 GO:0005737 cytoplasm
1.44 9.49e-20 GO:0005654 nucleoplasm
1.70 1.20e-18 GO:0030529 ribonucleoprotein complex
1.16 5.26e-18 GO:0044444 cytoplasmic part
1.26 6.05e-16 GO:0043228 non-membrane-bounded organelle
1.26 6.05e-16 GO:0043232 intracellular non-membrane-bounded organelle
1.22 6.52e-15 GO:0032991 macromolecular complex
1.29 3.95e-14 GO:0005829 cytosol
1.52 9.52e-10 GO:0005730 nucleolus
1.03 1.37e-07 GO:0044464 cell part
1.03 1.49e-07 GO:0005623 cell
1.38 1.67e-07 GO:0044451 nucleoplasm part
1.43 3.10e-07 GO:0005694 chromosome
1.73 1.04e-06 GO:0005840 ribosome
1.16 1.05e-05 GO:0043234 protein complex
1.81 1.10e-05 GO:0005681 spliceosomal complex
1.62 1.33e-05 GO:0016604 nuclear body
1.39 1.32e-04 GO:0044427 chromosomal part
1.72 1.51e-04 GO:0000793 condensed chromosome
1.22 1.67e-04 GO:0005739 mitochondrion
1.71 2.63e-04 GO:0000151 ubiquitin ligase complex
1.62 2.72e-04 GO:0031252 cell leading edge
1.95 4.98e-04 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
1.71 1.00e-03 GO:0016607 nuclear speck
1.90 1.04e-03 GO:0071013 catalytic step 2 spliceosome
1.58 2.16e-03 GO:0044454 nuclear chromosome part
1.51 2.90e-03 GO:0000228 nuclear chromosome
1.84 8.88e-03 GO:0022626 cytosolic ribosome
1.50 1.74e-02 GO:0005819 spindle
1.72 2.09e-02 GO:0001726 ruffle
1.74 2.24e-02 GO:0030027 lamellipodium
2.15 4.47e-02 GO:0022627 cytosolic small ribosomal subunit

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 1.65e-28 GO:0005515 protein binding
1.52 9.86e-17 GO:0003723 RNA binding
1.23 2.47e-16 GO:0003676 nucleic acid binding
1.08 3.66e-16 GO:0005488 binding
1.54 1.47e-07 GO:0003712 transcription cofactor activity
1.54 1.90e-07 GO:0000988 protein binding transcription factor activity
1.54 1.90e-07 GO:0000989 transcription factor binding transcription factor activity
1.77 1.69e-05 GO:0003735 structural constituent of ribosome
1.62 2.75e-05 GO:0003713 transcription coactivator activity
1.94 4.61e-04 GO:0008135 translation factor activity, nucleic acid binding
1.15 2.52e-03 GO:0003677 DNA binding
1.91 3.24e-03 GO:0047485 protein N-terminus binding
1.25 1.45e-02 GO:0019899 enzyme binding
1.58 1.95e-02 GO:0003714 transcription corepressor activity
1.13 3.52e-02 GO:0000166 nucleotide binding