Motif ID: EP300.p2

Z-value: 2.213


Transcription factors associated with EP300.p2:

Gene SymbolEntrez IDGene Name
EP300 2033 E1A binding protein p300

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EP300chr22_+_398177330.351.8e-01Click!


Activity profile for motif EP300.p2.

activity profile for motif EP300.p2


Sorted Z-values histogram for motif EP300.p2

Sorted Z-values for motif EP300.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EP300.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_6808025 1.750 LEPREL2
leprecan-like 2
chr13_-_43259032 1.727 NM_017993
 ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr4_-_122213018 1.599 NM_024574
 C4orf31
chromosome 4 open reading frame 31
chr1_-_29322993 1.562 NM_001003682
 TMEM200B
transmembrane protein 200B
chr4_+_172971149 1.538 NM_001034845
 GALNTL6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr14_-_50480857 1.497 NM_001163940
NM_002863
 PYGL

phosphorylase, glycogen, liver

chr9_-_129729518 1.400 NM_173492
 PIP5KL1
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr9_+_70107602 1.328 NM_199135
 FOXD4L3
FOXD4L6
forkhead box D4-like 3
forkhead box D4-like 6
chr17_+_56843893 1.299 NM_203425
 C17orf82
chromosome 17 open reading frame 82
chr17_+_69939130 1.270 NM_022036
 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr20_+_43468046 1.248 NM_001197139
NM_001048221
NM_001048222
NM_001197140
NM_018478
 DBNDD2




dysbindin (dystrobrevin binding protein 1) domain containing 2




chr7_-_117300763 1.162 NM_033427
 CTTNBP2
cortactin binding protein 2
chr7_+_128257698 1.129 NM_001127487
NM_001458
 FLNC

filamin C, gamma

chr9_+_114552871 1.118 NM_001012994
 SNX30
sorting nexin family member 30
chr2_-_230287442 1.117 NM_139072
 DNER
delta/notch-like EGF repeat containing
chr22_-_27405708 1.087 NM_001145418
 TTC28
tetratricopeptide repeat domain 28
chr19_+_12966970 1.085 NM_002501
 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr16_-_85099941 1.083 LOC400550
hypothetical LOC400550
chr4_+_183302105 1.053 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr10_-_134449467 1.030 NM_177400
 NKX6-2
NK6 homeobox 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 30 entries
enrichment   p-value GO term description
1.52 4.70e-02 GO:0009792 embryo development ending in birth or egg hatching
1.52 4.98e-02 GO:0043009 chordate embryonic development
1.50 5.65e-03 GO:0000904 cell morphogenesis involved in differentiation
1.41 4.16e-02 GO:0010629 negative regulation of gene expression
1.39 2.22e-04 GO:0032879 regulation of localization
1.39 2.45e-02 GO:0009790 embryo development
1.38 3.12e-02 GO:0051049 regulation of transport
1.35 1.84e-03 GO:0010646 regulation of cell communication
1.32 1.66e-04 GO:0007399 nervous system development
1.30 1.17e-04 GO:0023051 regulation of signaling
1.29 1.26e-05 GO:0030154 cell differentiation
1.29 1.11e-03 GO:0009653 anatomical structure morphogenesis
1.27 6.28e-05 GO:0048869 cellular developmental process
1.26 3.34e-02 GO:0009966 regulation of signal transduction
1.25 1.77e-06 GO:0048731 system development
1.23 2.49e-06 GO:0048856 anatomical structure development
1.23 3.20e-03 GO:0048523 negative regulation of cellular process
1.22 1.99e-03 GO:0048519 negative regulation of biological process
1.22 2.57e-03 GO:0048522 positive regulation of cellular process
1.22 3.30e-02 GO:0048513 organ development

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
2.16 5.69e-03 GO:0014069 postsynaptic density
1.66 3.97e-02 GO:0031252 cell leading edge
1.64 1.10e-05 GO:0045202 synapse
1.59 3.29e-03 GO:0044456 synapse part
1.46 1.71e-02 GO:0043005 neuron projection
1.44 6.68e-04 GO:0030054 cell junction
1.35 2.35e-03 GO:0005626 insoluble fraction
1.34 4.77e-03 GO:0005624 membrane fraction
1.30 3.49e-02 GO:0042995 cell projection
1.21 2.76e-03 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.36 5.35e-03 GO:0004714 transmembrane receptor protein tyrosine kinase activity
2.11 1.82e-02 GO:0019199 transmembrane receptor protein kinase activity
1.10 4.21e-04 GO:0005515 protein binding