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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: EWSR1-FLI1.p2

Z-value: 1.215

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_120029426	2.289	NM_001128933 NM_001128934 NM_133477	SYNPO2	synaptopodin 2
chr17_-_31146660	1.896	NM_001032278 NM_024302	MMP28	matrix metallopeptidase 28
chr14_-_53493198	1.857	NM_001202 NM_130850	BMP4	bone morphogenetic protein 4
chr4_-_86106567	1.751	NM_014991	WDFY3	WD repeat and FYVE domain containing 3
chr11_+_101485946	1.710	NM_001130145 NM_001195044 NM_006106	YAP1	Yes-associated protein 1
chr6_-_10520592	1.693	NM_001032280	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chrX_+_1361570	1.675	NM_001161530 NM_172247	CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr1_-_223907283	1.621	NM_001008493 NM_018212	ENAH	enabled homolog (Drosophila)
chr2_+_65069081	1.551	NM_001193493	SLC1A4	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr6_-_10520264	1.468		TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr2_+_113532685	1.466	NM_173170	IL1F5	interleukin 1 family, member 5 (delta)
chr2_+_113533155	1.435	NM_012275	IL1F5	interleukin 1 family, member 5 (delta)
chr1_-_68071635	1.293	NM_018841	GNG12	guanine nucleotide binding protein (G protein), gamma 12
chr1_-_68470585	1.286	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr1_-_93030538	1.284	NM_005665	EVI5	ecotropic viral integration site 5
chr2_+_37425240	1.235	NM_012413	QPCT	glutaminyl-peptide cyclotransferase
chr1_-_6468600	1.060	NM_001042665	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr6_-_132314004	1.002	NM_001901	CTGF	connective tissue growth factor
chr4_+_183302105	0.989		ODZ3	odz, odd Oz/ten-m homolog 3 (Drosophila)
chr19_-_1966628	0.954	NM_017797	BTBD2	BTB (POZ) domain containing 2
chr4_+_166519392	0.949	NM_001873	CPE	carboxypeptidase E
chr3_-_65999548	0.919	NM_001033057 NM_004742 NM_015520	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1
chr7_+_16759845	0.904	NM_014399	TSPAN13	tetraspanin 13
chr9_+_134843918	0.903	NM_001135031 NM_004188	GFI1B	growth factor independent 1B transcription repressor
chr9_+_77695334	0.899	NM_001190482 NM_006200	PCSK5	proprotein convertase subtilisin/kexin type 5
chr5_+_156819782	0.883		NIPAL4	NIPA-like domain containing 4
chr10_+_114700775	0.879		TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr11_-_122571198	0.876	NM_024769	CLMP	CXADR-like membrane protein
chr19_+_12996830	0.871		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr12_+_10222823	0.867	NM_153022	C12orf59	chromosome 12 open reading frame 59
chr6_-_134538762	0.821	NM_001143678	SGK1	serum/glucocorticoid regulated kinase 1
chr16_+_67697622	0.812	NM_138612	HAS3	hyaluronan synthase 3
chr12_+_55808696	0.811		LRP1	low density lipoprotein receptor-related protein 1
chr9_+_114552871	0.750	NM_001012994	SNX30	sorting nexin family member 30
chr12_+_55808514	0.736	NM_002332	LRP1	low density lipoprotein receptor-related protein 1
chr8_+_30361485	0.735	NM_001008710 NM_001008711 NM_001008712 NM_006867	RBPMS	RNA binding protein with multiple splicing
chr18_+_41659542	0.671	NM_213602	SIGLEC15	sialic acid binding Ig-like lectin 15
chr5_+_156819604	0.662	NM_001099287 NM_001172292	NIPAL4	NIPA-like domain containing 4
chr7_-_99365178	0.622	NM_181538	GJC3	gap junction protein, gamma 3, 30.2kDa
chr19_+_12996745	0.617		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr1_+_201711578	0.613		PRELP	proline/arginine-rich end leucine-rich repeat protein
chr10_-_35143900	0.601	NM_001184785 NM_001184786 NM_001184787 NM_001184788 NM_001184789 NM_001184790 NM_001184791 NM_001184792 NM_001184793 NM_001184794 NM_019619	PARD3	par-3 partitioning defective 3 homolog (C. elegans)
chr7_-_99411573	0.579	NM_001185	AZGP1	alpha-2-glycoprotein 1, zinc-binding
chr11_-_122571046	0.566		CLMP	CXADR-like membrane protein
chr17_+_45706786	0.556	NM_153229	TMEM92	transmembrane protein 92
chr12_-_47464143	0.546	NM_015270	ADCY6	adenylate cyclase 6
chr5_-_148422799	0.537	NM_024577	SH3TC2	SH3 domain and tetratricopeptide repeats 2
chr1_-_72521079	0.526
chr9_+_35528890	0.517		RUSC2	RUN and SH3 domain containing 2
chr12_+_107797985	0.490	NM_001917	DAO	D-amino-acid oxidase
chr8_+_133948384	0.489	NM_003235	TG	thyroglobulin
chr3_-_120878910	0.472	NM_005694	COX17	COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr11_-_66897584	0.471	NM_013246	CLCF1	cardiotrophin-like cytokine factor 1
chr11_-_117628211	0.446	NM_198275	MPZL3	myelin protein zero-like 3
chr1_+_185064654	0.439	NM_024420	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr3_+_143925904	0.438	NM_003304	TRPC1	transient receptor potential cation channel, subfamily C, member 1
chr20_+_6696744	0.429	NM_001200	BMP2	bone morphogenetic protein 2
chr9_-_83494198	0.428		TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr21_+_44544381	0.426		PFKL	phosphofructokinase, liver
chr19_-_47451119	0.425	NM_006494	ERF	Ets2 repressor factor
chr5_-_81082699	0.419	NM_012446	SSBP2	single-stranded DNA binding protein 2
chr1_-_155281785	0.418	NM_014784 NM_198236	ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11
chr7_+_21434818	0.417
chr16_+_84202515	0.413	NM_001134473	KIAA0182	KIAA0182
chr17_-_10574370	0.411	NM_001004313	TMEM220	transmembrane protein 220
chr21_+_44544392	0.407		PFKL	phosphofructokinase, liver
chr20_-_61755145	0.407	NM_015894	STMN3	stathmin-like 3
chr6_-_134538526	0.405		SGK1	serum/glucocorticoid regulated kinase 1
chr5_-_141981083	0.403	NM_001144892	FGF1	fibroblast growth factor 1 (acidic)
chr21_+_44544349	0.400	NM_002626	PFKL	phosphofructokinase, liver
chr10_+_23424383	0.387	NM_012228	MSRB2	methionine sulfoxide reductase B2
chr11_-_65244718	0.384	NM_032193	RNASEH2C	ribonuclease H2, subunit C
chr3_-_193928038	0.374	NM_004113	FGF12	fibroblast growth factor 12
chr1_-_20685314	0.366	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr20_-_47238310	0.366	NM_001037328 NM_004602 NM_017452 NM_017453 NM_017454	STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)
chr2_+_96269703	0.356	NM_001037228	LOC285033	hypothetical protein LOC285033
chr19_+_13066956	0.355		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr5_+_152850276	0.354	NM_000827 NM_001114183	GRIA1	glutamate receptor, ionotropic, AMPA 1
chr5_+_150020595	0.349	NM_001122853 NM_133371	MYOZ3	myozenin 3
chr12_+_44409743	0.341		ARID2	AT rich interactive domain 2 (ARID, RFX-like)
chr11_+_10433241	0.340	NM_001025389	AMPD3	adenosine monophosphate deaminase 3
chr17_+_30472710	0.336	NM_017559	FNDC8	fibronectin type III domain containing 8
chr14_+_69415880	0.336	NM_001034852 NM_022137	SMOC1	SPARC related modular calcium binding 1
chr3_+_33130563	0.335		CRTAP	cartilage associated protein
chr4_+_151218862	0.335	NM_001040260 NM_001040261	DCLK2	doublecortin-like kinase 2
chr11_+_10480891	0.334		AMPD3	adenosine monophosphate deaminase 3
chr19_-_60573552	0.334	NM_000641	IL11	interleukin 11
chr12_-_92489652	0.328		LOC144481	hypothetical protein LOC144481
chr6_+_139055244	0.326		FLJ46906	hypothetical LOC441172
chr11_-_65244486	0.318		RNASEH2C	ribonuclease H2, subunit C
chr11_-_93223315	0.318	NM_001144871	C11orf90	chromosome 11 open reading frame 90
chr20_+_29656744	0.317	NM_002165 NM_181353	ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr13_-_32678142	0.315	NM_052851	STARD13	StAR-related lipid transfer (START) domain containing 13
chr9_-_106705867	0.311		ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1
chr4_+_154345039	0.302	NM_015271	TRIM2	tripartite motif containing 2
chr2_-_24161033	0.300	NM_147184 NM_004881	TP53I3	tumor protein p53 inducible protein 3
chr6_+_117044334	0.299	NM_001010892 NM_001161664	RSPH4A	radial spoke head 4 homolog A (Chlamydomonas)
chr21_+_38550533	0.298	NM_002243	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr2_-_25418249	0.298	NM_022552	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha
chr9_-_129679760	0.297	NM_000476	AK1	adenylate kinase 1
chr17_-_36346240	0.291		KRT23	keratin 23 (histone deacetylase inducible)
chr3_-_188936941	0.290	NM_001130845	BCL6	B-cell CLL/lymphoma 6
chr1_+_201711505	0.288	NM_002725 NM_201348	PRELP	proline/arginine-rich end leucine-rich repeat protein
chr16_-_2848106	0.283	NM_022119	PRSS22	protease, serine, 22
chr12_+_44409762	0.282	NM_152641	ARID2	AT rich interactive domain 2 (ARID, RFX-like)
chr11_+_10434056	0.281	NM_001025390	AMPD3	adenosine monophosphate deaminase 3
chr1_+_109036431	0.279	NM_018061	PRPF38B	PRP38 pre-mRNA processing factor 38 (yeast) domain containing B
chr8_-_95556460	0.273	NM_012415	RAD54B	RAD54 homolog B (S. cerevisiae)
chr18_+_44319365	0.271	NM_001142397 NM_014772	CTIF	CBP80/20-dependent translation initiation factor
chr1_-_231498081	0.271	NM_014801	PCNXL2	pecanex-like 2 (Drosophila)
chr18_+_54682261	0.269		ZNF532	zinc finger protein 532
chr7_-_106991941	0.264	NM_001161520 NM_006348 NM_181733	COG5	component of oligomeric golgi complex 5
chr7_-_127458231	0.262	NM_022143	LRRC4	leucine rich repeat containing 4
chr9_-_106705780	0.260		ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1
chr17_+_43082302	0.259		KPNB1	karyopherin (importin) beta 1
chr1_-_155936904	0.259	NM_052939	FCRL3	Fc receptor-like 3
chr3_+_33130451	0.258	NM_006371	CRTAP	cartilage associated protein
chr12_+_14409875	0.257	NM_018179	ATF7IP	activating transcription factor 7 interacting protein
chr2_-_55349818	0.253	NM_001005369	MTIF2	mitochondrial translational initiation factor 2
chr7_+_36395913	0.249	NM_018685	ANLN	anillin, actin binding protein
chr1_+_26895108	0.244	NM_006015 NM_139135	ARID1A	AT rich interactive domain 1A (SWI-like)
chr19_-_44060729	0.242	NM_001195833 NM_198445	RINL	Ras and Rab interactor-like
chr12_+_92295738	0.242	NM_019094 NM_199040	NUDT4 NUDT4P1	nudix (nucleoside diphosphate linked moiety X)-type motif 4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1
chr19_-_60783996	0.241	NM_152600	ZNF579	zinc finger protein 579
chr9_-_103397023	0.240	NM_147180	PPP3R2	protein phosphatase 3, regulatory subunit B, beta
chr12_-_13139848	0.238	NM_031289 NM_153823	GSG1	germ cell associated 1
chr17_+_45488356	0.236		ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr14_+_22845851	0.231	NM_004050	BCL2L2-PABPN1 BCL2L2	BCL2L2-PABPN1 read-through transcript BCL2-like 2
chr20_+_43691797	0.229	NM_080753	WFDC10A	WAP four-disulfide core domain 10A
chr2_-_55349851	0.229	NM_002453	MTIF2	mitochondrial translational initiation factor 2
chr17_+_2443652	0.227	NM_000430	PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr6_-_143307976	0.225	NM_006734	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2
chr1_+_151596953	0.225	NM_002965	S100A9	S100 calcium binding protein A9
chr11_-_66898223	0.219	NM_001166212	CLCF1	cardiotrophin-like cytokine factor 1
chr12_+_54947293	0.217	NM_001099337	COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr1_-_180297372	0.213	NM_001009992	ZNF648	zinc finger protein 648
chr14_-_20636568	0.213	NM_016423	ZNF219	zinc finger protein 219
chr10_-_103864579	0.212		LDB1	LIM domain binding 1
chr16_-_69277355	0.212	NM_138383	MTSS1L	metastasis suppressor 1-like
chr15_-_77085056	0.212	NM_153815	RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1
chr7_+_116182676	0.203
chr20_+_42807901	0.195	NM_022358	KCNK15	potassium channel, subfamily K, member 15
chr1_+_44185005	0.195	NM_014652	IPO13	importin 13
chr9_+_35528628	0.195	NM_001135999	RUSC2	RUN and SH3 domain containing 2
chr7_-_99604127	0.193		GAL3ST4	galactose-3-O-sulfotransferase 4
chr17_+_45488330	0.192	NM_002204 NM_005501	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr1_-_26105477	0.191	NM_001145454 NM_005563	STMN1	stathmin 1
chr7_+_143043871	0.191	NM_001130026	FAM115C	family with sequence similarity 115, member C
chr2_+_149118791	0.189		EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr4_+_84676280	0.189		AGPAT9	1-acylglycerol-3-phosphate O-acyltransferase 9
chr15_+_88345612	0.188	NM_198526	ZNF710	zinc finger protein 710
chr12_+_54947180	0.188		COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr19_-_47450991	0.187		ERF	Ets2 repressor factor
chr10_+_106004457	0.186	NM_001191002 NM_004832	GSTO1	glutathione S-transferase omega 1
chr11_+_73034870	0.185	NM_001130033 NM_021200	PLEKHB1	pleckstrin homology domain containing, family B (evectins) member 1
chr1_-_20684858	0.185		CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr13_-_74953873	0.183	NM_014832	TBC1D4	TBC1 domain family, member 4
chr5_-_38631263	0.182	NM_002310	LIFR	leukemia inhibitory factor receptor alpha
chr1_-_72520735	0.180	NM_173808	NEGR1	neuronal growth regulator 1
chr15_+_39310757	0.180		CHP	calcium binding protein P22
chr12_-_48017223	0.179	NM_001008223	C1QL4	complement component 1, q subcomponent-like 4
chr12_-_54869511	0.177		SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr1_-_202730135	0.175		PIK3C2B	phosphoinositide-3-kinase, class 2, beta polypeptide
chr5_+_86599350	0.174		RASA1	RAS p21 protein activator (GTPase activating protein) 1
chr8_-_22982435	0.170	NM_003842 NM_147187	TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b
chr7_+_128142661	0.169	NM_032599	FAM71F1	family with sequence similarity 71, member F1
chr11_-_8788765	0.167	NM_213618	ST5	suppression of tumorigenicity 5
chr3_+_143925545	0.166
chr1_-_224563820	0.166	NM_173083	LIN9	lin-9 homolog (C. elegans)
chr1_-_171442937	0.165	NM_003326	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr11_-_76800525	0.164		PAK1	p21 protein (Cdc42/Rac)-activated kinase 1
chr2_+_182464910	0.161		SSFA2	sperm specific antigen 2
chr5_-_81082614	0.161		SSBP2	single-stranded DNA binding protein 2
chr11_-_8789457	0.161	NM_139157	ST5	suppression of tumorigenicity 5
chr16_-_69277194	0.158		MTSS1L	metastasis suppressor 1-like
chr1_-_224564038	0.158		LIN9	lin-9 homolog (C. elegans)
chr10_+_75211810	0.154	NM_203298	CHCHD1	coiled-coil-helix-coiled-coil-helix domain containing 1
chr21_+_38550739	0.153	NM_170736	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr7_-_99604171	0.153	NM_024637	GAL3ST4	galactose-3-O-sulfotransferase 4
chr17_-_34157962	0.153	NM_007144	PCGF2	polycomb group ring finger 2
chr2_+_182464713	0.151	NM_001130445 NM_006751	SSFA2	sperm specific antigen 2
chr19_-_53515143	0.148	NM_144577	CCDC114	coiled-coil domain containing 114
chr1_+_109969571	0.144	NM_203404	AMPD2	adenosine monophosphate deaminase 2
chr1_-_27802688	0.144	NM_001029882	AHDC1	AT hook, DNA binding motif, containing 1
chr5_-_64100239	0.143	NM_173829	SREK1IP1	SREK1-interacting protein 1
chr20_-_48741481	0.143
chr19_-_14447122	0.140		PTGER1	prostaglandin E receptor 1 (subtype EP1), 42kDa
chr17_-_34607257	0.140	NM_000723 NM_199247 NM_199248	CACNB1	calcium channel, voltage-dependent, beta 1 subunit
chr3_-_197529434	0.138	NM_152773	TCTEX1D2	Tctex1 domain containing 2
chr16_-_79811475	0.137	NM_001076780 NM_052892	PKD1L2	polycystic kidney disease 1-like 2
chr19_+_54786723	0.136	NM_020719	PRR12	proline rich 12
chr17_-_8004671	0.135		VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)
chr8_-_38127489	0.134	NM_000349	STAR	steroidogenic acute regulatory protein
chr19_-_55914837	0.134
chr6_-_25940247	0.134	NM_005074	SLC17A1	solute carrier family 17 (sodium phosphate), member 1
chrX_+_67635348	0.134	NM_001195214 NM_173834	YIPF6	Yip1 domain family, member 6
chr1_-_48235148	0.132	NM_001194986	LOC388630	UPF0632 protein A
chr1_+_117253882	0.132	NM_020440	PTGFRN	prostaglandin F2 receptor negative regulator
chr3_+_188131209	0.131		ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr20_-_47238082	0.131		STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.05	3.09e-03	GO:0009653	anatomical structure morphogenesis
2.94	8.87e-03	GO:0031175	neuron projection development
1.55	1.14e-02	GO:0023052	signaling
2.88	1.21e-02	GO:0048858	cell projection morphogenesis
2.85	1.39e-02	GO:0032990	cell part morphogenesis
2.62	1.49e-02	GO:0032989	cellular component morphogenesis
2.66	1.80e-02	GO:0000902	cell morphogenesis
2.59	1.89e-02	GO:0030030	cell projection organization
2.95	2.23e-02	GO:0048812	neuron projection morphogenesis
2.48	2.70e-02	GO:0030182	neuron differentiation
1.94	2.73e-02	GO:0007399	nervous system development
2.65	2.86e-02	GO:0048666	neuron development
13.58	3.22e-02	GO:0030501	positive regulation of bone mineralization
2.77	3.38e-02	GO:0000904	cell morphogenesis involved in differentiation
2.95	3.52e-02	GO:0007409	axonogenesis

Nothing significant found in compartment category.

Nothing significant found in function category.

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