ISMARA results: EWSR1-FLI1.p2

Motif ID: EWSR1-FLI1.p2

Z-value: 1.215

Transcription factors associated with EWSR1-FLI1.p2:

fusion protein between EWSR1 and FLI1 in an oncogenic event

Gene Symbol	Entrez ID	Gene Name
EWSR1	2130	Ewing sarcoma breakpoint region 1
FLI1	2313	Friend leukemia virus integration 1

Activity-expression correlation:

Gene	Promoter	Pearson	P-value	Plot
FLI1	chr11_+_128069183	-0.63	8.4e-03	Click!
EWSR1	chr22_+_27994216	-0.23	3.9e-01	Click!

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Showing 1 to 20 of 200 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_120029426	2.289	NM_001128933 NM_001128934 NM_133477	SYNPO2	synaptopodin 2
chr17_-_31146660	1.896	NM_001032278 NM_024302	MMP28	matrix metallopeptidase 28
chr14_-_53493198	1.857	NM_001202 NM_130850	BMP4	bone morphogenetic protein 4
chr4_-_86106567	1.751	NM_014991	WDFY3	WD repeat and FYVE domain containing 3
chr11_+_101485946	1.710	NM_001130145 NM_001195044 NM_006106	YAP1	Yes-associated protein 1
chr6_-_10520592	1.693	NM_001032280	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chrX_+_1361570	1.675	NM_001161530 NM_172247	CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr1_-_223907283	1.621	NM_001008493 NM_018212	ENAH	enabled homolog (Drosophila)
chr2_+_65069081	1.551	NM_001193493	SLC1A4	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr6_-_10520264	1.468		TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr2_+_113532685	1.466	NM_173170	IL1F5	interleukin 1 family, member 5 (delta)
chr2_+_113533155	1.435	NM_012275	IL1F5	interleukin 1 family, member 5 (delta)
chr1_-_68071635	1.293	NM_018841	GNG12	guanine nucleotide binding protein (G protein), gamma 12
chr1_-_68470585	1.286	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr1_-_93030538	1.284	NM_005665	EVI5	ecotropic viral integration site 5
chr2_+_37425240	1.235	NM_012413	QPCT	glutaminyl-peptide cyclotransferase
chr1_-_6468600	1.060	NM_001042665	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr6_-_132314004	1.002	NM_001901	CTGF	connective tissue growth factor
chr4_+_183302105	0.989		ODZ3	odz, odd Oz/ten-m homolog 3 (Drosophila)
chr19_-_1966628	0.954	NM_017797	BTBD2	BTB (POZ) domain containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

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Showing 1 to 15 of 15 entries

enrichment	p-value	GO term	description
13.58	3.22e-02	GO:0030501	positive regulation of bone mineralization
2.95	2.23e-02	GO:0048812	neuron projection morphogenesis
2.95	3.52e-02	GO:0007409	axonogenesis
2.94	8.87e-03	GO:0031175	neuron projection development
2.88	1.21e-02	GO:0048858	cell projection morphogenesis
2.85	1.39e-02	GO:0032990	cell part morphogenesis
2.77	3.38e-02	GO:0000904	cell morphogenesis involved in differentiation
2.66	1.80e-02	GO:0000902	cell morphogenesis
2.65	2.86e-02	GO:0048666	neuron development
2.62	1.49e-02	GO:0032989	cellular component morphogenesis
2.59	1.89e-02	GO:0030030	cell projection organization
2.48	2.70e-02	GO:0030182	neuron differentiation
2.05	3.09e-03	GO:0009653	anatomical structure morphogenesis
1.94	2.73e-02	GO:0007399	nervous system development
1.55	1.14e-02	GO:0023052	signaling