Motif ID: FOXN1.p2

Z-value: 1.526


Transcription factors associated with FOXN1.p2:

Gene SymbolEntrez IDGene Name
FOXN1 8456 forkhead box N1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXN1chr17_+_23875085-0.029.4e-01Click!


Activity profile for motif FOXN1.p2.

activity profile for motif FOXN1.p2


Sorted Z-values histogram for motif FOXN1.p2

Sorted Z-values for motif FOXN1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXN1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_36196523 2.058 NM_006194
PAX9
paired box 9
chr2_-_142605010 1.764 LRP1B
low density lipoprotein receptor-related protein 1B
chr10_+_103103797 1.657 NM_003939
NM_033637
BTRC

beta-transducin repeat containing

chr2_-_54051290 1.417 NM_014614
PSME4
proteasome (prosome, macropain) activator subunit 4
chr17_+_40581704 1.221 HEXIM1
hexamethylene bis-acetamide inducible 1
chr20_-_2592777 1.126 NM_006899
NM_174855
NM_174856
IDH3B


isocitrate dehydrogenase 3 (NAD+) beta


chr20_+_29656744 1.099 NM_002165
NM_181353
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr20_-_25010756 1.083 NM_014588
NM_199425
VSX1

visual system homeobox 1

chr14_+_30564433 1.079 NM_001128126
NM_007077
AP4S1

adaptor-related protein complex 4, sigma 1 subunit

chr1_-_45924770 1.070 NM_021639
GPBP1L1
GC-rich promoter binding protein 1-like 1
chr20_+_3749164 1.052 NM_018347
C20orf29
chromosome 20 open reading frame 29
chrX_+_90920915 1.038 NM_032967
PCDH11X
PCDH11Y
protocadherin 11 X-linked
protocadherin 11 Y-linked
chr4_-_170770111 1.037 NM_012224
NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr3_+_139388770 0.943 NM_014154
NM_015396
NM_213654
ARMC8


armadillo repeat containing 8


chr14_-_87859284 0.933 NM_138317
KCNK10
potassium channel, subfamily K, member 10
chr4_+_81475897 0.915 NM_152770
C4orf22
chromosome 4 open reading frame 22
chr17_-_42250961 0.878 NM_030753
WNT3
wingless-type MMTV integration site family, member 3
chr2_+_30523586 0.870 NM_182551
NM_001002257
LCLAT1

lysocardiolipin acyltransferase 1

chr20_+_3775421 0.869 NM_020746
MAVS
mitochondrial antiviral signaling protein
chr5_+_80292213 0.837 RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 45 entries
enrichment   p-value GO term description
1.98 1.27e-02 GO:0006511 ubiquitin-dependent protein catabolic process
1.94 2.22e-02 GO:0019941 modification-dependent protein catabolic process
1.93 2.65e-02 GO:0043632 modification-dependent macromolecule catabolic process
1.89 4.49e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.73 1.50e-05 GO:0006351 transcription, DNA-dependent
1.72 4.34e-06 GO:0032774 RNA biosynthetic process
1.72 7.03e-03 GO:0000278 mitotic cell cycle
1.72 2.24e-02 GO:0044265 cellular macromolecule catabolic process
1.64 1.51e-03 GO:0022402 cell cycle process
1.64 1.31e-02 GO:0022403 cell cycle phase
1.63 1.02e-09 GO:0016070 RNA metabolic process
1.58 7.41e-04 GO:0007049 cell cycle
1.54 1.49e-07 GO:0010467 gene expression
1.53 1.30e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.51 2.53e-08 GO:0090304 nucleic acid metabolic process
1.50 2.38e-05 GO:0034645 cellular macromolecule biosynthetic process
1.49 3.50e-05 GO:0009059 macromolecule biosynthetic process
1.44 2.75e-08 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37 1.88e-11 GO:0044260 cellular macromolecule metabolic process
1.37 1.17e-03 GO:0048523 negative regulation of cellular process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
2.75 6.40e-03 GO:0005875 microtubule associated complex
1.82 4.23e-02 GO:0005874 microtubule
1.77 3.71e-02 GO:0005815 microtubule organizing center
1.64 1.23e-03 GO:0015630 microtubule cytoskeleton
1.62 1.05e-07 GO:0005654 nucleoplasm
1.61 1.99e-03 GO:0044451 nucleoplasm part
1.51 9.58e-08 GO:0031981 nuclear lumen
1.42 1.19e-06 GO:0070013 intracellular organelle lumen
1.40 7.23e-06 GO:0043233 organelle lumen
1.40 1.69e-05 GO:0044428 nuclear part
1.39 8.17e-06 GO:0031974 membrane-enclosed lumen
1.34 2.79e-15 GO:0005634 nucleus
1.23 1.16e-06 GO:0044446 intracellular organelle part
1.23 3.97e-03 GO:0032991 macromolecular complex
1.22 5.15e-14 GO:0043231 intracellular membrane-bounded organelle
1.22 7.24e-14 GO:0043227 membrane-bounded organelle
1.22 5.35e-06 GO:0044422 organelle part
1.20 2.06e-23 GO:0044424 intracellular part
1.19 4.49e-13 GO:0043229 intracellular organelle
1.19 2.75e-09 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.54 7.24e-04 GO:0030528 transcription regulator activity
1.49 6.30e-03 GO:0001071 nucleic acid binding transcription factor activity
1.49 6.30e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.33 3.36e-06 GO:0003676 nucleic acid binding
1.32 2.40e-03 GO:0003677 DNA binding
1.17 4.31e-05 GO:0005515 protein binding
1.10 2.67e-05 GO:0005488 binding