Motif ID: GATA6.p2

Z-value: 1.386


Transcription factors associated with GATA6.p2:

Gene SymbolEntrez IDGene Name
GATA6 2627 GATA binding protein 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA6chr18_+_18003401-0.077.9e-01Click!


Activity profile for motif GATA6.p2.

activity profile for motif GATA6.p2


Sorted Z-values histogram for motif GATA6.p2

Sorted Z-values for motif GATA6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_22200735 2.216 NM_005747
CELA3A
chymotrypsin-like elastase family, member 3A
chr5_-_34020445 1.992 NM_001012509
NM_016180
SLC45A2

solute carrier family 45, member 2

chr21_-_38792173 1.850 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr12_-_119249938 1.725 NM_000928
PLA2G1B
phospholipase A2, group IB (pancreas)
chr1_+_200698493 1.580 NM_032103
NM_032104
PPP1R12B

protein phosphatase 1, regulatory (inhibitor) subunit 12B

chr2_+_158666627 1.488 NM_173355
UPP2
uridine phosphorylase 2
chr1_+_22176004 1.428 NM_007352
CELA3A
CELA3B
chymotrypsin-like elastase family, member 3A
chymotrypsin-like elastase family, member 3B
chr6_-_30236667 1.368 NM_006778
NM_052828
TRIM10

tripartite motif containing 10

chr11_-_114593838 1.338 CADM1
cell adhesion molecule 1
chr7_+_143287952 1.320 NM_012369
OR2F1
olfactory receptor, family 2, subfamily F, member 1
chr11_+_118463906 1.259 NM_001024382
HMBS
hydroxymethylbilane synthase
chr19_+_40541327 1.231 NM_005304
FFAR3
free fatty acid receptor 3
chr11_+_75106512 1.206 NM_025098
MOGAT2
monoacylglycerol O-acyltransferase 2
chr7_-_36991189 1.115 NM_001039459
ELMO1
engulfment and cell motility 1
chr2_+_241456834 1.112 NM_000030
AGXT
alanine-glyoxylate aminotransferase
chr1_-_24342158 1.106 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr1_+_198263352 1.071 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr1_+_110795271 1.049 NM_032414
PROK1
prokineticin 1
chrX_-_44945025 0.990 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr22_+_21543671 0.972 IGLV4-3
immunoglobulin lambda variable 4-3
chr11_+_120966280 0.972 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr18_+_13610866 0.959 NM_004338
NM_181483
C18orf1

chromosome 18 open reading frame 1

chr10_+_70745615 0.943 NM_033496
HK1
hexokinase 1
chr6_-_46155937 0.920 NM_001114086
CLIC5
chloride intracellular channel 5
chr12_+_70618892 0.900 NM_173353
TPH2
tryptophan hydroxylase 2
chr21_+_36458708 0.879 NM_005128
DOPEY2
dopey family member 2
chr3_-_139333813 0.862 NM_016161
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr7_-_99312591 0.859 NM_001005276
OR2AE1
olfactory receptor, family 2, subfamily AE, member 1
chr5_+_156540425 0.842 NM_005546
ITK
IL2-inducible T-cell kinase
chr1_-_201321999 0.841 NM_002479
MYOG
myogenin (myogenic factor 4)
chr17_+_4621924 0.840 NM_003963
TM4SF5
transmembrane 4 L six family member 5
chr3_+_139200347 0.836 NM_001002026
CLDN18
claudin 18
chr3_-_15538164 0.819 NM_005677
NM_080539
COLQ

collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase

chr15_-_88023576 0.818 NM_001145311
NM_002666
PLIN1

perilipin 1

chr11_-_83071084 0.817 NM_001142702
DLG2
discs, large homolog 2 (Drosophila)
chr19_+_40824486 0.816 NM_014209
ETV2
ets variant 2
chr9_-_116732403 0.807 NM_001244
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
chr11_+_123282307 0.786 NM_001005197
OR8D4
olfactory receptor, family 8, subfamily D, member 4
chr8_-_124818754 0.785 NM_001003954
NM_004306
ANXA13

annexin A13

chr1_+_43063817 0.774 NM_018538
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr6_+_41118214 0.769 NM_001010873
NM_001159726
TSPO2

translocator protein 2

chr2_-_74424041 0.766 NM_133478
SLC4A5
solute carrier family 4, sodium bicarbonate cotransporter, member 5
chrX_+_65152004 0.760


chr22_+_21559959 0.753 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr1_-_180636373 0.751 NM_172000
TEDDM1
transmembrane epididymal protein 1
chr4_-_186934059 0.733 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr6_-_138581319 0.722 NM_021635
PBOV1
prostate and breast cancer overexpressed 1
chr7_-_93027057 0.699 NM_001164738
CALCR
calcitonin receptor
chrX_-_50403412 0.693 SHROOM4
shroom family member 4
chr10_-_14856901 0.689 NM_031453
FAM107B
family with sequence similarity 107, member B
chr9_+_96561750 0.686 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chr11_+_57123927 0.685 SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr1_-_203657803 0.683 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr1_+_204484081 0.673 NM_001910
NM_148964
CTSE

cathepsin E

chr11_-_19038803 0.668 NM_054030
MRGPRX2
MAS-related GPR, member X2
chr12_+_54132264 0.666 NM_054105
OR6C2
olfactory receptor, family 6, subfamily C, member 2
chr5_+_145296313 0.665 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr1_-_171442937 0.664 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr2_-_178461710 0.662 NM_001077196
PDE11A
phosphodiesterase 11A
chr3_-_47909001 0.662 MAP4
microtubule-associated protein 4
chr1_+_17121012 0.627 NM_014675
CROCC
ciliary rootlet coiled-coil, rootletin
chr12_-_68291208 0.626 NM_201550
LRRC10
leucine rich repeat containing 10
chr7_+_142459538 0.615 NM_001001667
OR6V1
olfactory receptor, family 6, subfamily V, member 1
chr12_-_11230809 0.614 NM_181429
TAS2R42
taste receptor, type 2, member 42
chr1_+_152560179 0.613 NM_080429
AQP10
aquaporin 10
chr1_-_201321711 0.609 MYOG
myogenin (myogenic factor 4)
chrX_-_15312390 0.593 NM_004469
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr8_-_27157157 0.582 STMN4
stathmin-like 4
chr11_-_5523328 0.581 NM_001005289
OR52H1
olfactory receptor, family 52, subfamily H, member 1
chr7_-_76667045 0.578 NM_006682
FGL2
fibrinogen-like 2
chr3_+_185233312 0.577 NM_001163646
HTR3D
5-hydroxytryptamine (serotonin) receptor 3 family member D
chr5_-_16795336 0.574 MYO10
myosin X
chr7_+_143378393 0.571 NM_012365
OR2A5
olfactory receptor, family 2, subfamily A, member 5
chr1_-_204179169 0.566 NM_052934
NM_134325
SLC26A9

solute carrier family 26, member 9

chr7_+_18296569 0.562 HDAC9
histone deacetylase 9
chr1_-_120285753 0.559 NOTCH2
notch 2
chr12_-_6103945 0.551 NM_000552
VWF
von Willebrand factor
chr17_+_72047709 0.550 NM_001077620
PRCD
progressive rod-cone degeneration
chrX_-_55074125 0.550 NM_000032
NM_001037967
NM_001037968
ALAS2


aminolevulinate, delta-, synthase 2


chr15_-_48626193 0.549 NM_203494
USP50
ubiquitin specific peptidase 50
chr3_-_120861959 0.548 NM_022135
POPDC2
popeye domain containing 2
chr10_-_104587069 0.545 NM_000102
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr10_-_116408046 0.543 NM_002313
ABLIM1
actin binding LIM protein 1
chr15_-_41879426 0.535 NM_001033517
SERINC4
serine incorporator 4
chr3_+_101811122 0.528 NM_032787
GPR128
G protein-coupled receptor 128
chr1_+_242281199 0.526 ZNF238
zinc finger protein 238
chr4_+_14985272 0.526 NM_001135171
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr2_+_89715037 0.525


chr7_+_127020924 0.525 NM_020369
FSCN3
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr6_-_35873034 0.523 NM_001832
CLPS
colipase, pancreatic
chr14_-_80934523 0.520 NM_033104
STON2
stonin 2
chr11_+_73034870 0.518 NM_001130033
NM_021200
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr11_-_56914668 0.511 NM_002728
PRG2
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
chr11_+_4617520 0.506 NM_001004751
OR51D1
olfactory receptor, family 51, subfamily D, member 1
chr17_-_36594652 0.506 NM_033060
KRTAP4-1
keratin associated protein 4-1
chr4_-_72868598 0.505 NM_000583
GC
group-specific component (vitamin D binding protein)
chr9_-_128910132 0.505 ANGPTL2
angiopoietin-like 2
chr14_+_75058591 0.504 BATF
basic leucine zipper transcription factor, ATF-like
chr14_+_71065794 0.501 NM_015556
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr12_-_94914133 0.500 NM_002108
HAL
histidine ammonia-lyase
chrX_+_38096679 0.499 NM_000531
OTC
ornithine carbamoyltransferase
chr2_+_173794692 0.496 ZAK
sterile alpha motif and leucine zipper containing kinase AZK
chr1_+_17817397 0.495 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr7_+_142136892 0.493 NM_002769
PRSS1
PRSS2
protease, serine, 1 (trypsin 1)
protease, serine, 2 (trypsin 2)
chr4_-_52578542 0.493 NM_001024611
LRRC66
leucine rich repeat containing 66
chr7_-_122627235 0.482 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr17_-_44400952 0.479 NM_004123
GIP
gastric inhibitory polypeptide
chr1_-_120155581 0.475 NM_001159352
NM_001159353
NM_032044
REG4


regenerating islet-derived family, member 4


chr12_-_66905802 0.475 NM_018402
IL26
interleukin 26
chr16_+_24765052 0.472 NM_052944
SLC5A11
solute carrier family 5 (sodium/glucose cotransporter), member 11
chr22_+_18330049 0.471 NM_007310
COMT
catechol-O-methyltransferase
chr5_-_160044844 0.468 ATP10B
ATPase, class V, type 10B
chr3_-_195601283 0.466 NM_004488
GP5
glycoprotein V (platelet)
chrX_+_37750778 0.465 NM_001163335
NM_138780
SYTL5

synaptotagmin-like 5

chrX_+_135558001 0.463 NM_000074
CD40LG
CD40 ligand
chrX_+_135106578 0.462 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr19_+_40632456 0.460 NM_005306
FFAR2
free fatty acid receptor 2
chr8_-_20084892 0.459 NM_001135691
NM_001142324
NM_001142325
NM_003053
SLC18A1



solute carrier family 18 (vesicular monoamine), member 1



chr4_-_186970366 0.454 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr2_-_144711375 0.453 NM_024659
GTDC1
glycosyltransferase-like domain containing 1
chr19_-_60241424 0.452 NM_001083899
NM_016363
GP6

glycoprotein VI (platelet)

chr2_-_98646367 0.449 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr7_+_143646150 0.444 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr5_-_176868483 0.441 DOK3
docking protein 3
chr1_+_242281175 0.441 NM_205768
ZNF238
zinc finger protein 238
chr3_+_52788976 0.437 NM_001166435
NM_001166436
ITIH1

inter-alpha (globulin) inhibitor H1

chr15_+_34720097 0.437 NM_032499
C15orf41
chromosome 15 open reading frame 41
chr3_+_115099007 0.436 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr3_+_187866464 0.435 NM_000412
HRG
histidine-rich glycoprotein
chr5_-_35083996 0.434 NM_031900
AGXT2
alanine--glyoxylate aminotransferase 2
chrX_+_44588192 0.434 NM_022076
DUSP21
dual specificity phosphatase 21
chr12_-_51298599 0.430 NM_175068
KRT73
keratin 73
chr12_-_51514328 0.429 NM_175834
KRT79
keratin 79
chr8_+_17440664 0.428 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr1_-_153477673 0.424 NM_001171812
NM_000157
GBA

glucosidase, beta, acid

chr1_-_43509187 0.420 EBNA1BP2
EBNA1 binding protein 2
chr22_+_20880159 0.419 IGLV6-57
immunoglobulin lambda variable 6-57
chrX_+_7147471 0.418 NM_000351
STS
steroid sulfatase (microsomal), isozyme S
chr7_-_142369534 0.418 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr1_+_195503956 0.417 NM_001193640
NM_201253
CRB1

crumbs homolog 1 (Drosophila)

chr3_+_88270951 0.417 NM_018293
ZNF654
zinc finger protein 654
chr5_-_59100091 0.416 PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_43919392 0.415 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr1_-_151333624 0.412 NM_001024209
SPRR2E
small proline-rich protein 2E
chr13_-_32658215 0.412 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr13_+_77213295 0.411 NM_144595
SLAIN1
SLAIN motif family, member 1
chr17_-_45196465 0.409 FAM117A
family with sequence similarity 117, member A
chr1_+_169484256 0.406 NM_002021
FMO1
flavin containing monooxygenase 1
chr17_-_4747147 0.406 NM_000080
CHRNE
cholinergic receptor, nicotinic, epsilon
chr8_-_7297296 0.406 NM_058206
NM_058207
SPAG11B

sperm associated antigen 11B

chr17_+_41432452 0.404 NM_001007532
STH
saitohin
chrX_+_106048245 0.404 NM_001171095
CLDN2
claudin 2
chr14_+_75058518 0.403 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chr1_+_100957883 0.403 NM_001078
NM_080682
VCAM1

vascular cell adhesion molecule 1

chr3_-_113701073 0.403 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr16_+_24696069 0.402 TNRC6A
trinucleotide repeat containing 6A
chr6_-_32251654 0.401 AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr7_-_99170651 0.401 NM_000765
CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7
chr1_+_173303616 0.400 NM_022093
TNN
tenascin N
chr16_+_80086454 0.398 NM_030629
CMIP
c-Maf-inducing protein
chr2_-_138762909 0.398


chr1_-_100416358 0.397 NM_144620
LRRC39
leucine rich repeat containing 39
chr7_+_143263191 0.397 NM_001004685
OR2F2
olfactory receptor, family 2, subfamily F, member 2
chr14_-_93919305 0.396 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr4_+_151722526 0.395 NM_006439
MAB21L2
mab-21-like 2 (C. elegans)
chr17_-_45196516 0.392 NM_030802
FAM117A
family with sequence similarity 117, member A
chr3_-_152585226 0.389 NM_022788
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr11_-_26700121 0.389 NM_178498
SLC5A12
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr19_-_52750924 0.387 NM_001101419
ZNF541
zinc finger protein 541
chrX_+_119379967 0.386 NM_001142447
NM_012069
ATP1B4

ATPase, Na+/K+ transporting, beta 4 polypeptide

chr6_-_24985432 0.382 NM_015864
FAM65B
family with sequence similarity 65, member B
chr2_+_207512522 0.382 NM_173077
CPO
carboxypeptidase O
chr15_-_40537002 0.381 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr22_+_49523489 0.376 NM_001097
ACR
acrosin
chr16_+_15503623 0.374 NM_001142469
C16orf45
chromosome 16 open reading frame 45
chr20_+_56369012 0.373


chr4_+_73116384 0.372 NM_004885
NPFFR2
neuropeptide FF receptor 2
chr10_-_48010879 0.370 NM_002900
RBP3
retinol binding protein 3, interstitial
chr6_+_132933153 0.370 NM_175067
TAAR6
trace amine associated receptor 6
chr11_-_128217550 0.369 NM_000220
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr16_-_4778317 0.369 NM_001154458
NM_144605
SEPT12

septin 12

chr6_-_36412562 0.368 NM_001010903
C6orf222
chromosome 6 open reading frame 222
chr10_-_134449467 0.367 NM_177400
NKX6-2
NK6 homeobox 2
chr1_+_151456683 0.367 NM_001195571
PRR9
proline rich 9
chr22_+_21079355 0.362


chr18_+_27425727 0.359 NM_000371
TTR
transthyretin
chr12_-_14982708 0.358 NM_152321
ERP27
endoplasmic reticulum protein 27
chr14_+_75141557 0.357 NM_001195283
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr19_+_9984861 0.355 NM_015725
RDH8
retinol dehydrogenase 8 (all-trans)
chr12_+_8167494 0.354 NM_016184
NM_194447
NM_194448
NM_194450
CLEC4A



C-type lectin domain family 4, member A



chr6_-_50097606 0.353 NM_001037497
NM_001037728
DEFB110

defensin, beta 110 locus

chr16_-_11282595 0.352 NM_002761
PRM1
protamine 1
chr17_-_36418869 0.351 NM_031958
KRTAP3-1
keratin associated protein 3-1
chrX_+_15435351 0.350 NM_001721
BMX
BMX non-receptor tyrosine kinase
chr11_-_129268113 0.349 NM_006165
NFRKB
nuclear factor related to kappaB binding protein
chr9_+_138810610 0.344 NM_001039374
KIAA1984
KIAA1984
chr1_+_246290586 0.343 NM_001004687
OR2L3
olfactory receptor, family 2, subfamily L, member 3
chr12_+_43972732 0.342 NM_001142678
ANO6
anoctamin 6
chr12_+_52105131 0.338 AMHR2
anti-Mullerian hormone receptor, type II
chr5_-_156705250 0.338 NM_001001343
FNDC9
fibronectin type III domain containing 9

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.19 4.23e-15 GO:0007606 sensory perception of chemical stimulus
2.02 4.24e-15 GO:0003008 system process
3.31 9.40e-15 GO:0007608 sensory perception of smell
1.47 1.50e-14 GO:0032501 multicellular organismal process
2.53 1.80e-14 GO:0007600 sensory perception
2.04 4.72e-12 GO:0050877 neurological system process
1.34 1.70e-09 GO:0050896 response to stimulus
4.80 4.19e-07 GO:0007586 digestion
11.44 1.04e-03 GO:0044241 lipid digestion
2.68 1.63e-03 GO:0008202 steroid metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.51 2.45e-13 GO:0071944 cell periphery
1.50 7.03e-13 GO:0005886 plasma membrane
1.63 6.06e-08 GO:0005576 extracellular region
1.24 5.91e-05 GO:0044425 membrane part
1.19 1.97e-04 GO:0016020 membrane
1.25 3.25e-04 GO:0031224 intrinsic to membrane
1.24 8.48e-04 GO:0016021 integral to membrane
2.60 1.05e-03 GO:0045177 apical part of cell
2.80 1.43e-03 GO:0016324 apical plasma membrane
1.65 1.57e-03 GO:0044421 extracellular region part
1.67 1.25e-02 GO:0005615 extracellular space
1.37 1.28e-02 GO:0044459 plasma membrane part
3.72 4.38e-02 GO:0031091 platelet alpha granule

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.31 1.38e-14 GO:0004984 olfactory receptor activity
2.24 1.70e-10 GO:0004930 G-protein coupled receptor activity
1.94 6.93e-10 GO:0004888 transmembrane receptor activity
1.78 1.37e-09 GO:0004872 receptor activity
1.62 1.30e-07 GO:0004871 signal transducer activity
1.62 1.30e-07 GO:0060089 molecular transducer activity