Motif ID: GFI1B.p2

Z-value: 1.197


Transcription factors associated with GFI1B.p2:

Gene SymbolEntrez IDGene Name
GFI1B 8328 growth factor independent 1B transcription repressor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GFI1Bchr9_+_1348439180.381.5e-01Click!


Activity profile for motif GFI1B.p2.

activity profile for motif GFI1B.p2


Sorted Z-values histogram for motif GFI1B.p2

Sorted Z-values for motif GFI1B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_28016182 3.376 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr4_+_183302105 2.162 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr4_+_15080586 2.006 NM_001080522
NM_001164720
NM_020785
CC2D2A


coiled-coil and C2 domain containing 2A


chr2_-_142605010 1.905 LRP1B
low density lipoprotein receptor-related protein 1B
chr3_-_192063158 1.539 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr11_-_102100833 1.329 NM_002424
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr19_-_10489606 1.227 NM_001166215
S1PR5
sphingosine-1-phosphate receptor 5
chr15_+_60146467 1.221 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr1_-_188713324 1.210 NM_199051
FAM5C
family with sequence similarity 5, member C
chr1_+_50348052 1.068 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_-_53849929 1.058 NM_017763
RNF43
ring finger protein 43
chr1_-_116184846 1.015 NM_001111061
NHLH2
nescient helix loop helix 2
chr2_-_189752575 0.965 NM_000393
COL5A2
collagen, type V, alpha 2
chr8_-_114518194 0.947 NM_052900
NM_198123
CSMD3

CUB and Sushi multiple domains 3

chr6_-_134540666 0.927 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr12_-_22378833 0.924 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr1_+_61642287 0.915 NFIA
nuclear factor I/A
chr3_+_190372456 0.864 NM_198485
TPRG1
tumor protein p63 regulated 1
chrX_-_10548458 0.844 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr14_+_95792299 0.840 NM_000710
BDKRB1
bradykinin receptor B1
chr5_-_59100091 0.813 PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_-_81744469 0.812 NM_001717
BNC1
basonuclin 1
chr22_+_27779877 0.801 ZNRF3
zinc and ring finger 3
chr17_-_67628523 0.773 FLJ37644
hypothetical LOC400618
chr17_+_56884560 0.755 TBX4
T-box 4
chr15_-_74091817 0.733 NM_138573
NRG4
neuregulin 4
chr3_+_134976965 0.723 TF
transferrin
chrX_-_21586337 0.722 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr9_+_1040367 0.719 DMRT2
doublesex and mab-3 related transcription factor 2
chr2_+_204440753 0.711 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr1_-_116185215 0.678 NM_005599
NHLH2
nescient helix loop helix 2
chr9_+_1040333 0.663 NM_006557
NM_001130865
DMRT2

doublesex and mab-3 related transcription factor 2

chr2_-_133895795 0.658 NCKAP5
NCK-associated protein 5
chr14_+_20580224 0.654 NM_032572
RNASE7
ribonuclease, RNase A family, 7
chr18_+_3441589 0.639 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr20_+_186376 0.607 NM_207469
DEFB132
defensin, beta 132
chr17_-_53849888 0.600 RNF43
ring finger protein 43
chr2_-_113259441 0.597 NM_000575
IL1A
interleukin 1, alpha
chr4_-_77147625 0.593 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr12_-_91346054 0.578 NM_001025232
CLLU1OS
chronic lymphocytic leukemia up-regulated 1 opposite strand
chrX_+_17303727 0.565 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr14_-_72430545 0.547 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr11_-_102219450 0.545 NM_002422
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr4_-_87247829 0.538 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr1_+_61697209 0.529 NFIA
nuclear factor I/A
chr17_+_67628763 0.506 SOX9
SRY (sex determining region Y)-box 9
chr1_+_218768146 0.505 MARK1
MAP/microtubule affinity-regulating kinase 1
chr8_+_62363078 0.505 NM_173519
CLVS1
clavesin 1
chr17_+_67628772 0.501 SOX9
SRY (sex determining region Y)-box 9
chr7_-_113346284 0.493 NM_002711
PPP1R3A
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr3_-_69064364 0.493 NM_001005527
NM_182522
FAM19A4

family with sequence similarity 19 (chemokine (C-C motif)-like), member A4

chr18_+_53863865 0.490 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr5_-_146441184 0.487 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr11_+_22316242 0.477 NM_020346
SLC17A6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr12_+_119617060 0.466


chr8_-_18710575 0.464 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr5_+_66160359 0.458 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_-_214963279 0.454 NM_001438
ESRRG
estrogen-related receptor gamma
chr3_+_99555387 0.451 NM_001005517
OR5K4
olfactory receptor, family 5, subfamily K, member 4
chr17_-_36181927 0.449 NM_181539
KRT26
keratin 26
chrX_+_17303270 0.447 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr14_-_36121536 0.445 NM_014360
NKX2-8
NK2 homeobox 8
chr11_-_35503720 0.441 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr4_+_86968069 0.441 ARHGAP24
Rho GTPase activating protein 24
chr11_-_64484184 0.427 NM_001037225
C11orf85
chromosome 11 open reading frame 85
chr11_+_22644732 0.423 NM_001143830
GAS2
growth arrest-specific 2
chr3_-_188936941 0.409 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr19_-_14108400 0.406 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr12_-_23993830 0.402 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr7_+_47801413 0.398 NM_025031
PKD1L1
C7orf69
polycystic kidney disease 1 like 1
chromosome 7 open reading frame 69
chr3_-_191522886 0.395 NM_021101
CLDN1
claudin 1
chr9_-_106401514 0.393 NM_001004482
OR13C5
olfactory receptor, family 13, subfamily C, member 5
chrX_+_147608302 0.389 NM_001170628
AFF2
AF4/FMR2 family, member 2
chrX_+_17303798 0.383 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr2_-_37269193 0.382 NM_001032377
SULT6B1
sulfotransferase family, cytosolic, 6B, member 1
chr14_+_19761708 0.381 NM_001004480
OR11H6
olfactory receptor, family 11, subfamily H, member 6
chr19_+_51190535 0.378 CCDC61
coiled-coil domain containing 61
chr2_-_165133239 0.374 GRB14
growth factor receptor-bound protein 14
chr19_+_45794895 0.373 NM_001042544
LTBP4
latent transforming growth factor beta binding protein 4
chr17_+_11864841 0.371 NM_003010
MAP2K4
mitogen-activated protein kinase kinase 4
chr18_+_30327243 0.370 NM_001198945
NM_001392
NM_032975
NM_032979
DTNA



dystrobrevin, alpha



chr7_-_16471817 0.367 NM_015464
SOSTDC1
sclerostin domain containing 1
chr1_-_151352587 0.361 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr11_+_111294810 0.353 NM_080659
C11orf52
chromosome 11 open reading frame 52
chr7_+_65731289 0.348 NM_001167961
NM_153033
KCTD7

potassium channel tetramerisation domain containing 7

chr15_+_38296920 0.345 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr3_-_113842652 0.344 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chrX_+_17303458 0.344 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr17_-_34575939 0.344 NM_001143968
ARL5C
ADP-ribosylation factor-like 5C
chr18_-_33399997 0.343 NM_001025087
NM_001025088
NM_001025089
NM_020180
CELF4



CUGBP, Elav-like family member 4



chr18_+_30327341 0.339 DTNA
dystrobrevin, alpha
chr14_-_49652944 0.339 NM_001040662
NM_024558
METTL21D

methyltransferase like 21D

chr3_-_139333813 0.334 NM_016161
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr7_+_116238309 0.332 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr19_+_14108974 0.331


chr2_-_156897286 0.327 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr10_+_89257569 0.317 NM_001178118
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr2_+_219180862 0.311 PLCD4
phospholipase C, delta 4
chr4_+_41234944 0.310 LIMCH1
LIM and calponin homology domains 1
chr20_-_3013335 0.309 NM_000490
AVP
arginine vasopressin
chr3_+_187840842 0.305 NM_014375
FETUB
fetuin B
chr3_+_2117246 0.301 NM_175607
CNTN4
contactin 4
chr3_-_155630197 0.299 NM_001038705
GPR149
G protein-coupled receptor 149
chr20_-_56859352 0.297 GNAS-AS1
GNAS antisense RNA 1 (non-protein coding)
chr2_+_98070026 0.294 NM_144992
VWA3B
von Willebrand factor A domain containing 3B
chr1_+_162795538 0.293 PBX1
pre-B-cell leukemia homeobox 1
chr2_-_164300758 0.287 NM_018086
FIGN
fidgetin
chr6_-_130578110 0.285 NM_152552
SAMD3
sterile alpha motif domain containing 3
chr4_-_44348414 0.285 NM_182592
YIPF7
Yip1 domain family, member 7
chr8_-_17624304 0.283 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chr17_-_36451189 0.275 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr1_-_115433570 0.272 NM_005725
TSPAN2
tetraspanin 2
chr15_+_100163424 0.271 NM_001005326
OR4F6
olfactory receptor, family 4, subfamily F, member 6
chr7_+_65731364 0.271 KCTD7
potassium channel tetramerisation domain containing 7
chr1_-_177378801 0.270 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr3_-_152449591 0.268 NM_001081455
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr14_-_57834558 0.268 FLJ31306
hypothetical LOC379025
chr1_+_161305188 0.266 NM_005613
RGS4
regulator of G-protein signaling 4
chr7_+_89681069 0.266 NM_001040666
STEAP2
six transmembrane epithelial antigen of the prostate 2
chr16_-_88656092 0.264 NM_052996
PRDM7
PR domain containing 7
chr2_+_170370290 0.260 SSB
Sjogren syndrome antigen B (autoantigen La)
chr3_-_113842350 0.258 CCDC80
coiled-coil domain containing 80
chr12_-_83954185 0.257 NM_001100917
TSPAN19
tetraspanin 19
chr11_-_128279670 0.256 C11orf45
chromosome 11 open reading frame 45
chr18_-_39111243 0.256 NM_020783
SYT4
synaptotagmin IV
chr2_+_62754489 0.254 NM_001142615
EHBP1
EH domain binding protein 1
chr12_+_54760153 0.252 NM_001005915
NM_001982
ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

chr4_+_41235077 0.252 LIMCH1
LIM and calponin homology domains 1
chr7_+_18515488 0.252 HDAC9
histone deacetylase 9
chr1_-_17180659 0.252 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr6_-_52060327 0.251 NM_138694
NM_170724
PKHD1

polycystic kidney and hepatic disease 1 (autosomal recessive)

chr17_+_67628749 0.250 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr1_+_107485071 0.249 NTNG1
netrin G1
chr4_-_187114407 0.247 SORBS2
sorbin and SH3 domain containing 2
chr2_+_219180875 0.247 NM_032726
PLCD4
phospholipase C, delta 4
chr12_+_83954229 0.244 NM_001079910
NM_032165
LRRIQ1

leucine-rich repeats and IQ motif containing 1

chr17_+_38256886 0.243


chr2_+_162908828 0.241 NM_012198
GCA
grancalcin, EF-hand calcium binding protein
chr1_+_219026661 0.241 NM_022746
MOSC1
MOCO sulphurase C-terminal domain containing 1
chr3_-_159872960 0.240 NM_020169
LXN
latexin
chr1_-_197173159 0.238 LOC100131234
familial acute myelogenous leukemia related factor
chr14_-_106149623 0.234


chr3_-_18455207 0.233 NM_001131010
SATB1
SATB homeobox 1
chr2_+_219180821 0.231 PLCD4
phospholipase C, delta 4
chr17_-_36074812 0.231 NM_152349
KRT222
keratin 222
chr3_+_113200696 0.229 NM_001008273
TAGLN3
transgelin 3
chr4_-_88669267 0.228 SPARCL1
SPARC-like 1 (hevin)
chr13_-_77391525 0.226


chr19_-_14108267 0.225 ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr7_+_28415495 0.224 LOC401317
hypothetical LOC401317
chr1_-_240679380 0.223 NM_001195811
NM_001195812
PLD5

phospholipase D family, member 5

chr7_-_81910956 0.222 NM_000722
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr8_-_93099040 0.221 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr16_+_2747491 0.221


chr19_-_48815572 0.221 ZNF428
zinc finger protein 428
chr2_+_88148413 0.219 NM_198274
SMYD1
SET and MYND domain containing 1
chr1_+_161305558 0.216 NM_001113381
RGS4
regulator of G-protein signaling 4
chr5_-_22889487 0.214 NM_004061
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr11_+_111551417 0.213 NM_031938
BCO2
beta-carotene oxygenase 2
chr7_+_18515440 0.212 HDAC9
histone deacetylase 9
chr15_+_74416156 0.210 NM_145805
ISL2
ISL LIM homeobox 2
chr12_-_69434330 0.210 PTPRR
protein tyrosine phosphatase, receptor type, R
chrX_+_15428820 0.206 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr12_-_18782184 0.196 NM_033123
PLCZ1
phospholipase C, zeta 1
chr1_+_86785346 0.195 NM_012128
CLCA4
chloride channel accessory 4
chr9_-_72219359 0.195 NM_001206
KLF9
Kruppel-like factor 9
chr12_-_7709734 0.195 NM_001644
APOBEC1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr19_-_42355172 0.194 NM_199126
ZNF585A
zinc finger protein 585A
chr3_-_113842553 0.194 CCDC80
coiled-coil domain containing 80
chr6_-_138862271 0.193 NM_001144060
NHSL1
NHS-like 1
chr7_-_56069324 0.193 PSPH
phosphoserine phosphatase
chr9_-_106407728 0.192 NM_001004481
OR13C2
olfactory receptor, family 13, subfamily C, member 2
chrX_+_145698993 0.191 NM_001144064
CXorf51
chromosome X open reading frame 51
chr1_-_68470585 0.191 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr14_+_57834962 0.190 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr18_+_3402071 0.189 NM_174886
TGIF1
TGFB-induced factor homeobox 1
chr14_-_23117268 0.187 JPH4
junctophilin 4
chr5_-_150264622 0.186 ZNF300
zinc finger protein 300
chr6_+_99389300 0.186 NM_005604
POU3F2
POU class 3 homeobox 2
chr15_+_89570333 0.184 SV2B
synaptic vesicle glycoprotein 2B
chr20_-_38751289 0.178 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr11_+_34599227 0.175 EHF
ets homologous factor
chr2_+_166034402 0.175 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr13_-_35327798 0.174 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr3_-_148604760 0.173 NM_001168378
ZIC4
Zic family member 4
chr12_+_18782307 0.173 NM_033328
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr17_-_8139330 0.173 SLC25A35
solute carrier family 25, member 35
chr9_-_90983501 0.173 NM_016848
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr7_+_63410620 0.172 NM_001170905
ZNF736
zinc finger protein 736
chr16_+_70117523 0.172 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr7_+_100169184 0.171 NM_003386
NM_173059
ZAN

zonadhesin

chr12_-_52960168 0.171 NM_012117
CBX5
chromobox homolog 5
chr5_-_20024050 0.171 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr12_+_70618892 0.170 NM_173353
TPH2
tryptophan hydroxylase 2
chr12_-_52960146 0.170 CBX5
chromobox homolog 5
chr18_+_45342398 0.169 NM_006033
LIPG
lipase, endothelial
chr6_+_154373323 0.169 NM_001145279
NM_001145280
NM_001145281
OPRM1


opioid receptor, mu 1


chr2_-_201930311 0.167 NM_001127391
NM_139163
ALS2CR12

amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12

chr22_+_42726423 0.167 NM_001003828
PARVB
parvin, beta
chr15_+_80741827 0.166 LOC80154
hypothetical LOC80154

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.37 1.58e-04 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.65 5.21e-05 GO:0005576 extracellular region

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.47 3.86e-02 GO:0004871 signal transducer activity
1.47 3.86e-02 GO:0060089 molecular transducer activity