Motif ID: GTF2A1,2.p2

Z-value: 1.317


Transcription factors associated with GTF2A1,2.p2:

Gene SymbolEntrez IDGene Name
GTF2A1 2957 general transcription factor IIA, 1, 19/37kDa
GTF2A2 2958 general transcription factor IIA, 2, 12kDa

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GTF2A1chr14_-_80757327-0.341.9e-01Click!
GTF2A2chr15_-_577368280.243.8e-01Click!


Activity profile for motif GTF2A1,2.p2.

activity profile for motif GTF2A1,2.p2


Sorted Z-values histogram for motif GTF2A1,2.p2

Sorted Z-values for motif GTF2A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2A1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_167504070 1.865 NM_001145121
TCP10L2
TCP10
t-complex 10-like 2 (mouse)
t-complex 10 homolog (mouse)
chr22_+_20068039 1.675 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr8_+_7663908 1.655 NM_001164447
FAM90A10
family with sequence similarity 90, member A10
chr19_-_60573552 1.619 NM_000641
IL11
interleukin 11
chr6_-_167717907 1.611 NM_004610
TCP10
t-complex 10 homolog (mouse)
chr22_+_20067662 1.593 NM_001128633
RIMBP3C
RIMS binding protein 3C
chr10_-_116382089 1.574 ABLIM1
actin binding LIM protein 1
chr11_+_5610060 1.484 NM_130390
TRIM34
tripartite motif containing 34
chr6_+_144649142 1.466 UTRN
utrophin
chr1_+_228949752 1.160 NM_006615
NM_016452
CAPN9

calpain 9

chr20_+_17622319 1.070 NM_001159495
BANF2
barrier to autointegration factor 2
chr11_+_57547928 1.056 NM_001005212
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr22_+_21852911 1.029 BCR
breakpoint cluster region
chr7_+_105304445 1.012 LOC100506768
CDHR3
hypothetical LOC100506768
cadherin-related family member 3
chr17_+_45488356 1.005 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr17_+_36493927 0.992 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr17_-_58239382 0.942 NM_152598
MARCH10
membrane-associated ring finger (C3HC4) 10
chr17_+_45488330 0.942 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr8_-_7427584 0.929 NM_001136572
FAM90A7
family with sequence similarity 90, member A7
chr1_-_202432165 0.910 NM_002256
KISS1
KiSS-1 metastasis-suppressor
chr1_+_42391678 0.906 NM_007102
GUCA2B
guanylate cyclase activator 2B (uroguanylin)
chr4_+_9094611 0.881 NM_001040071
LOC650293
seven transmembrane helix receptor
chr1_+_201729893 0.872 NM_014359
OPTC
opticin
chr16_+_54072969 0.864 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr8_+_7132323 0.853 NM_001164455
FAM90A5
family with sequence similarity 90, member A5
chr8_+_7610374 0.852 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr8_-_18585721 0.851 PSD3
pleckstrin and Sec7 domain containing 3
chr17_-_70220605 0.850 NM_139018
CD300LF
CD300 molecule-like family member f
chr7_-_142816019 0.837 NM_005232
EPHA1
EPH receptor A1
chr7_+_127668566 0.824 NM_000230
LEP
leptin
chr17_+_74542066 0.814 NM_198593
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_-_6400470 0.813 NM_001165966
NM_031220
PITPNM3

PITPNM family member 3

chr1_-_166372244 0.809 NM_153832
GPR161
G protein-coupled receptor 161
chr2_+_132890616 0.808 NM_001508
GPR39
G protein-coupled receptor 39
chr16_+_68765428 0.806 NM_173619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr1_+_111571803 0.803 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr8_+_7124701 0.802 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr16_-_48418418 0.792 NM_015069
ZNF423
zinc finger protein 423
chr19_-_51690989 0.789 NM_020709
PNMAL2
PNMA-like 2
chr8_-_7404643 0.775 NM_001136572
FAM90A7
family with sequence similarity 90, member A7
chr6_-_167491305 0.772 NM_005299
GPR31
G protein-coupled receptor 31
chr7_-_105304159 0.766 NM_020725
NM_152749
ATXN7L1

ataxin 7-like 1

chr16_-_73012740 0.760 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr8_+_7139945 0.755 NM_001164453
FAM90A20
family with sequence similarity 90, member A20
chr22_-_20419975 0.750 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr13_+_31503436 0.747 NM_023037
FRY
furry homolog (Drosophila)
chr8_+_7101835 0.747 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr3_-_48105287 0.745 MAP4
microtubule-associated protein 4
chr8_-_23233426 0.736 LOXL2
lysyl oxidase-like 2
chr8_+_7648613 0.736 NM_001164451
NM_001164449
FAM90A18
FAM90A19
family with sequence similarity 90, member A18
family with sequence similarity 90, member A19
chr1_-_54127993 0.718 YIPF1
Yip1 domain family, member 1
chr5_+_60663842 0.716 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr6_+_151688327 0.701 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr22_+_21852699 0.701 BCR
breakpoint cluster region
chr2_+_17861266 0.696 NM_001105569
MSGN1
mesogenin 1
chr5_+_175041069 0.695 NM_022304
HRH2
histamine receptor H2
chr1_-_54128060 0.693 NM_018982
YIPF1
Yip1 domain family, member 1
chr20_-_55718351 0.683 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr5_+_150000394 0.674 NM_001109974
NM_007286
SYNPO

synaptopodin

chr8_+_7618022 0.674 NM_001164451
NM_001164449
FAM90A18
FAM90A19
family with sequence similarity 90, member A18
family with sequence similarity 90, member A19
chr17_-_36456949 0.670 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr22_+_21006814 0.663


chr22_+_21116283 0.660


chr10_+_70745615 0.654 NM_033496
HK1
hexokinase 1
chr8_+_7633318 0.636 NM_001164450
FAM90A8
family with sequence similarity 90, member A8
chr3_+_38282301 0.628 NM_004256
SLC22A13
solute carrier family 22 (organic anion transporter), member 13
chr7_-_105106844 0.627 NM_138495
ATXN7L1
ataxin 7-like 1
chr7_+_116182676 0.612


chr22_+_21484240 0.607


chr5_-_145464124 0.605 NM_001029869
PLAC8L1
PLAC8-like 1
chr5_+_150008030 0.602 SYNPO
synaptopodin
chr19_-_14944729 0.600 NM_005071
SLC1A6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr8_+_7656261 0.600 NM_001164448
FAM90A9
family with sequence similarity 90, member A9
chr19_+_8814268 0.597 NM_145208
MBD3L1
methyl-CpG binding domain protein 3-like 1
chr17_-_70039187 0.595 NM_174892
CD300LB
CD300 molecule-like family member b
chr5_+_110587546 0.590 NM_001744
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr1_-_143786993 0.582 NM_022359
PDE4DIP
phosphodiesterase 4D interacting protein
chr15_-_81175542 0.579 NM_004644
AP3B2
adaptor-related protein complex 3, beta 2 subunit
chrX_+_149282097 0.578 NM_001177465
MAMLD1
mastermind-like domain containing 1
chr12_+_51777715 0.576 IGFBP6
insulin-like growth factor binding protein 6
chr14_-_22693333 0.574 NM_182728
SLC7A8
solute carrier family 7 (amino acid transporter, L-type), member 8
chr17_-_36587965 0.573 NM_033062
KRTAP4-2
keratin associated protein 4-2
chr15_-_47042932 0.570 NM_203349
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr22_+_21359175 0.570 IGLV3-25
immunoglobulin lambda variable 3-25
chr21_-_35153664 0.567 RUNX1
runt-related transcription factor 1
chr15_-_72282581 0.563 NM_001142618
STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr6_-_31977747 0.561 NM_181842
ZBTB12
zinc finger and BTB domain containing 12
chr7_-_526005 0.551 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr21_-_32879617 0.551 NM_144659
TCP10L
t-complex 10 (mouse)-like
chr20_+_55718619 0.547


chr9_-_135334003 0.547 NM_001145099
NM_017585
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr18_-_71268576 0.544 NM_001037331
C18orf62
chromosome 18 open reading frame 62
chr11_-_85074848 0.544 NM_152723
CCDC89
coiled-coil domain containing 89
chr5_+_145296313 0.544 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr5_-_171813960 0.543 SH3PXD2B
SH3 and PX domains 2B
chr19_-_59516155 0.543 NM_181879
NM_181985
NM_181986
NM_021250
LILRA5



leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5



chr19_-_56178882 0.542 NM_139277
NM_005046
KLK7

kallikrein-related peptidase 7

chr1_-_24342158 0.541 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr8_+_37672427 0.541 NM_025069
ZNF703
zinc finger protein 703
chr6_-_31973418 0.533 EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr2_+_178893216 0.531 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr21_+_44597911 0.528 NM_003307
TRPM2
transient receptor potential cation channel, subfamily M, member 2
chr11_+_119586879 0.527 NM_178507
OAF
OAF homolog (Drosophila)
chr1_-_205012348 0.527 NM_000572
IL10
interleukin 10
chr19_+_5855842 0.525 NM_001017921
VMAC
vimentin-type intermediate filament associated coiled-coil protein
chr19_+_59777049 0.523 NM_001130917
NM_006866
LILRA2

leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2

chr6_+_36752244 0.523 NM_078467
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr12_+_32546243 0.516 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_+_205105776 0.501 NM_018724
IL20
interleukin 20
chr1_-_68470585 0.500 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr5_+_60969392 0.500 NM_173667
FLJ37543
hypothetical protein FLJ37543
chr1_-_32940943 0.499 NM_001161708
NM_030786
SYNC

syncoilin, intermediate filament protein

chr12_+_51777684 0.490 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr1_+_52964609 0.490 NM_024646
ZYG11B
zyg-11 homolog B (C. elegans)
chr15_-_72282452 0.489 STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chrX_+_24290798 0.484 NM_001136234
FAM48B1
family with sequence similarity 48, member B1
chr1_-_16812274 0.483 NM_017940
NBPF1
neuroblastoma breakpoint family, member 1
chr17_-_36346240 0.482 KRT23
keratin 23 (histone deacetylase inducible)
chr4_-_26100986 0.482 NM_000730
CCKAR
cholecystokinin A receptor
chr20_+_55718718 0.482


chr17_-_45621140 0.481


chr6_-_31973434 0.474 NM_006709
NM_025256
EHMT2

euchromatic histone-lysine N-methyltransferase 2

chr6_-_24985432 0.470 NM_015864
FAM65B
family with sequence similarity 65, member B
chr1_-_172199799 0.463 RC3H1
ring finger and CCCH-type domains 1
chr19_+_40895669 0.463 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr17_-_59342319 0.461 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chr5_-_56283672 0.459 NM_152622
MIER3
mesoderm induction early response 1, family member 3
chr9_+_130620540 0.458 NM_004435
ENDOG
endonuclease G
chr1_-_20179495 0.458 NM_000300
NM_001161727
NM_001161728
PLA2G2A


phospholipase A2, group IIA (platelets, synovial fluid)


chr1_-_24307514 0.458 MYOM3
myomesin family, member 3
chr22_+_21065202 0.458


chr6_+_43247179 0.457 SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr5_+_156752739 0.455 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr1_+_21639146 0.454 NM_032264
NBPF3
neuroblastoma breakpoint family, member 3
chr16_+_80086454 0.449 NM_030629
CMIP
c-Maf-inducing protein
chr5_-_16670085 0.448 NM_001034850
FAM134B
family with sequence similarity 134, member B
chr6_-_35804337 0.448 NM_001145775
FKBP5
FK506 binding protein 5
chr20_+_31106797 0.447 NM_182658
C20orf185
chromosome 20 open reading frame 185
chr6_-_27907283 0.446 NM_003541
HIST1H4A
HIST1H4F
HIST1H4K
HIST1H4J
histone cluster 1, H4a
histone cluster 1, H4f
histone cluster 1, H4k
histone cluster 1, H4j
chr20_-_55718982 0.445 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr21_-_26294332 0.443 APP
amyloid beta (A4) precursor protein
chr1_+_183970093 0.441 NM_031935
HMCN1
hemicentin 1
chr2_-_69467825 0.441 NM_002056
GFPT1
glutamine--fructose-6-phosphate transaminase 1
chr15_-_81412354 0.441 NM_004839
NM_199330
NM_199331
NM_199332
HOMER2



homer homolog 2 (Drosophila)



chr4_-_75123193 0.438 NM_002090
CXCL3
chemokine (C-X-C motif) ligand 3
chr7_+_142885087 0.438 NM_176883
TAS2R41
taste receptor, type 2, member 41
chr11_+_113155727 0.436 NM_001101389
CLDN25
claudin 25
chr17_-_70039107 0.434 CD300LB
CD300 molecule-like family member b
chr7_-_27158726 0.433


chr6_+_112481970 0.433 NM_003880
NM_198239
WISP3

WNT1 inducible signaling pathway protein 3

chr6_-_116973465 0.426 NM_001139444
BET3L
BET3 like (S. cerevisiae)
chr1_-_154536051 0.422 NM_001004319
VHLL
von Hippel-Lindau tumor suppressor-like
chr1_-_155336223 0.422 NM_001004341
ETV3L
ets variant 3-like
chr15_-_88256922 0.417 NM_001199058
NM_182616
C15orf38-AP3S2
C15orf38
C15orf38-AP3S2 readthrough
chromosome 15 open reading frame 38
chr6_+_131613196 0.415 NM_004842
NM_138633
AKAP7

A kinase (PRKA) anchor protein 7

chr2_-_160181206 0.413 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr5_-_171814026 0.411 NM_001017995
SH3PXD2B
SH3 and PX domains 2B
chr10_+_74323344 0.410 NM_152635
OIT3
oncoprotein induced transcript 3
chr22_+_19699441 0.409 NM_001159554
NM_005446
P2RX6

purinergic receptor P2X, ligand-gated ion channel, 6

chr6_+_150505849 0.406 NM_030949
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr1_-_56817568 0.404 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_+_13903936 0.402 NM_012231
NM_015866
PRDM2

PR domain containing 2, with ZNF domain

chr17_-_45633986 0.402 NM_000088
COL1A1
collagen, type I, alpha 1
chr21_-_42247007 0.401 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr9_-_135232790 0.401 NM_033161
SURF4
surfeit 4
chr1_-_202402043 0.401 NM_000537
REN
renin
chr7_+_100557098 0.401 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr20_+_51022352 0.399 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr14_-_50367513 0.399 NM_016350
NM_020921
NM_182944
NM_182946
NIN



ninein (GSK3B interacting protein)



chr17_-_21097170 0.398 NM_152914
C17orf103
chromosome 17 open reading frame 103
chr22_+_21065207 0.396 IGLJ3
immunoglobulin lambda joining 3
chr17_-_58237742 0.394 NM_001100875
MARCH10
membrane-associated ring finger (C3HC4) 10
chr18_+_606671 0.393 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr19_-_47328399 0.392 NM_002698
POU2F2
POU class 2 homeobox 2
chr1_-_56817717 0.391 PPAP2B
phosphatidic acid phosphatase type 2B
chr5_+_156628929 0.387 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr1_-_42402973 0.387 NM_033553
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr17_-_69869552 0.385 NM_001080466
BTBD17
BTB (POZ) domain containing 17
chr7_+_134893185 0.383 NM_015135
NUP205
nucleoporin 205kDa
chr6_-_26393705 0.380 NM_003543
HIST1H4H
histone cluster 1, H4h
chr11_+_1064869 0.379 NM_002457
MUC2
mucin 2, oligomeric mucus/gel-forming
chr6_-_32259974 0.378 NM_001136
NM_172197
AGER

advanced glycosylation end product-specific receptor

chr1_+_22107137 0.376 RPL21
ribosomal protein L21
chr2_+_128119908 0.376 NM_001161415
NM_001161416
NM_001161417
NM_005291
GPR17



G protein-coupled receptor 17



chrX_+_130019896 0.375 NM_144967
ARHGAP36
Rho GTPase activating protein 36
chr13_-_39075200 0.372 LHFP
lipoma HMGIC fusion partner
chr8_-_12033677 0.371 NM_201402
USP17L2
ubiquitin specific peptidase 17-like 2
chr4_+_77829743 0.371 SHROOM3
shroom family member 3
chr1_+_42701460 0.371 CCDC30
coiled-coil domain containing 30
chr1_+_32311084 0.368 NM_018056
TMEM39B
transmembrane protein 39B
chr5_-_142057692 0.368 NM_001144934
NM_001144935
FGF1

fibroblast growth factor 1 (acidic)

chr21_-_42608774 0.367 NM_003226
TFF3
trefoil factor 3 (intestinal)
chr1_+_46418786 0.366 TSPAN1
tetraspanin 1
chr9_+_130231027 0.365 CERCAM
cerebral endothelial cell adhesion molecule
chr1_+_151223180 0.365 NM_005987
SPRR1A
small proline-rich protein 1A
chr8_-_134378630 0.364 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr1_+_204710208 0.364 NM_001193321
NM_001193322
NM_014002
IKBKE


inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon


chr8_-_133841988 0.363 NM_001145153
NM_144649
TMEM71

transmembrane protein 71

chr14_-_22358752 0.362 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr19_+_59777085 0.359 LILRA2
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.27 5.60e-03 GO:0005576 extracellular region
1.38 2.13e-02 GO:0044421 extracellular region part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 2.50e-02 GO:0005515 protein binding