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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: GTF2I.p2

Z-value: 2.382

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_+_17714070	5.038	NM_001112741 NM_004976	KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1
chrX_+_144707022	3.650	NM_001144003 NM_001144004 NM_001144005 NM_032539	SLITRK2	SLIT and NTRK-like family, member 2
chr15_-_86600658	3.473	NM_001007156 NM_001012338 NM_002530	NTRK3	neurotrophic tyrosine kinase, receptor, type 3
chr12_+_6800950	3.168	NM_014449 NM_019858	GPR162	G protein-coupled receptor 162
chr2_+_45022540	3.035	NM_005413	SIX3	SIX homeobox 3
chr18_-_21184824	2.943
chr14_-_60185659	2.904	NM_005982	SIX1	SIX homeobox 1
chr18_-_28606839	2.890	NM_020805	KLHL14	kelch-like 14 (Drosophila)
chr13_+_99431417	2.854
chr2_-_200030944	2.845	NM_001172509	SATB2	SATB homeobox 2
chrX_+_136476353	2.834		ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)
chr17_-_44047299	2.816	NM_024016	HOXB8	homeobox B8
chr13_+_57103944	2.645		PCDH17	protocadherin 17
chr13_+_57103789	2.604	NM_001040429	PCDH17	protocadherin 17
chr8_+_104582151	2.528	NM_001100117	RIMS2	regulating synaptic membrane exocytosis 2
chr14_-_36058648	2.496	NM_003317	NKX2-1	NK2 homeobox 1
chr1_+_26609893	2.449		LIN28A	lin-28 homolog A (C. elegans)
chr14_-_23117614	2.434		JPH4	junctophilin 4
chr12_+_93066370	2.426	NM_005761	PLXNC1	plexin C1
chr10_+_102495327	2.421	NM_000278 NM_003987 NM_003988 NM_003989 NM_003990	PAX2	paired box 2
chr1_-_29322993	2.383	NM_001003682	TMEM200B	transmembrane protein 200B
chr11_-_27697768	2.303	NM_001143807	BDNF	brain-derived neurotrophic factor
chr3_-_193609531	2.286	NM_021032	FGF12	fibroblast growth factor 12
chr2_+_104837004	2.260
chr3_+_54131731	2.251	NM_018398	CACNA2D3	calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr4_-_122213018	2.176	NM_024574	C4orf31	chromosome 4 open reading frame 31
chr7_+_128218685	2.160		CCDC136	coiled-coil domain containing 136
chr10_+_94823636	2.113	NM_000783	CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1
chr14_-_23117833	2.095	NM_001146028 NM_032452	JPH4	junctophilin 4
chr13_+_87122778	1.972	NM_015567	SLITRK5	SLIT and NTRK-like family, member 5
chr1_+_26609819	1.955	NM_024674	LIN28A	lin-28 homolog A (C. elegans)
chr19_-_55763091	1.887	NM_001080457	LRRC4B	leucine rich repeat containing 4B
chr11_-_30564338	1.881	NM_001145399	MPPED2	metallophosphoesterase domain containing 2
chr12_-_56418295	1.873	NM_001122772	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr3_+_54131613	1.846		CACNA2D3	calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr3_+_11009436	1.821		SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr20_-_22512893	1.817		FOXA2	forkhead box A2
chr19_-_53841064	1.783	NM_001217	CA11	carbonic anhydrase XI
chr7_+_86111803	1.765		GRM3	glutamate receptor, metabotropic 3
chr16_-_10183616	1.750	NM_001134407	GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr18_+_44319365	1.727	NM_001142397 NM_014772	CTIF	CBP80/20-dependent translation initiation factor
chr4_+_109308126	1.717		LOC641518	hypothetical LOC641518
chr6_+_1335067	1.692	NM_001452	FOXF2	forkhead box F2
chr19_-_52666886	1.685		SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2
chr16_-_10184111	1.683	NM_000833	GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr11_-_62445308	1.671		CHRM1	cholinergic receptor, muscarinic 1
chr2_+_200031333	1.667
chr19_-_11452439	1.661	NM_001420 NM_032281	ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr2_-_200030412	1.659		SATB2	SATB homeobox 2
chrX_+_136475979	1.650	NM_003413	ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)
chr11_-_44288188	1.606	NM_021926	ALX4	ALX homeobox 4
chr9_-_34579679	1.589	NM_001842 NM_147164	CNTFR	ciliary neurotrophic factor receptor
chr4_-_5940893	1.587		CRMP1	collapsin response mediator protein 1
chr11_-_18769703	1.577	NM_001039970 NM_006906 NM_032781	PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr4_-_1156959	1.569	NM_001128325	SPON2	spondin 2, extracellular matrix protein
chr4_-_46690197	1.561	NM_000809	GABRA4	gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr19_-_52667056	1.557	NM_015063	SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2
chr9_+_8848130	1.551
chr17_+_35036936	1.550		PPP1R1B	protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr13_-_27441290	1.544	NM_001265	CDX2	caudal type homeobox 2
chr5_-_134397470	1.527		PITX1	paired-like homeodomain 1
chr20_-_61755145	1.511	NM_015894	STMN3	stathmin-like 3
chr16_-_2776606	1.503	NM_152891	PRSS33	protease, serine, 33
chr3_-_62334229	1.501	NM_018008	FEZF2	FEZ family zinc finger 2
chr13_-_27441143	1.500		CDX2	caudal type homeobox 2
chr4_+_147779492	1.498	NM_004575	POU4F2	POU class 4 homeobox 2
chr17_-_72045218	1.495	NM_134268	CYGB	cytoglobin
chrX_-_74062005	1.488	NM_001008537	KIAA2022	KIAA2022
chr13_-_27441423	1.478		CDX2	caudal type homeobox 2
chr20_+_21634293	1.467	NM_006192	PAX1	paired box 1
chr8_-_93184629	1.441	NM_001198633 NM_175634	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_144994038	1.434		ZEB2	zinc finger E-box binding homeobox 2
chr5_+_175231210	1.432		CPLX2	complexin 2
chr2_-_219558517	1.423	NM_017521	FEV	FEV (ETS oncogene family)
chr12_-_21818881	1.413	NM_004982	KCNJ8	potassium inwardly-rectifying channel, subfamily J, member 8
chr1_-_155095289	1.412	NM_014215	INSRR	insulin receptor-related receptor
chr15_-_24569309	1.411	NM_000814	GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3
chr12_+_56291484	1.408	NM_182947	ARHGEF25	Rho guanine nucleotide exchange factor (GEF) 25
chr7_+_5289079	1.395	NM_001040661 NM_153247	SLC29A4	solute carrier family 29 (nucleoside transporters), member 4
chr5_-_134397740	1.392	NM_002653	PITX1	paired-like homeodomain 1
chr9_-_85342868	1.391	NM_174938	FRMD3	FERM domain containing 3
chr14_+_28306633	1.385		FOXG1	forkhead box G1
chr5_+_175231170	1.385
chr8_-_21702273	1.383	NM_001165038 NM_001165039 NM_001495	GFRA2	GDNF family receptor alpha 2
chr11_-_72063059	1.372	NM_002599	PDE2A	phosphodiesterase 2A, cGMP-stimulated
chr17_+_35036704	1.372	NM_032192	PPP1R1B	protein phosphatase 1, regulatory (inhibitor) subunit 1B
chrX_-_111970662	1.352	NM_133265	AMOT	angiomotin
chrX_-_137621060	1.347		FGF13	fibroblast growth factor 13
chr7_+_86112012	1.332		GRM3	glutamate receptor, metabotropic 3
chr17_+_35036728	1.331		PPP1R1B	protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr12_-_43556338	1.326		NELL2	NEL-like 2 (chicken)
chr5_+_139008667	1.310		CXXC5	CXXC finger protein 5
chr2_+_219432789	1.293	NM_006522	WNT6	wingless-type MMTV integration site family, member 6
chr15_+_64782468	1.291		SMAD6	SMAD family member 6
chr1_+_109458247	1.286		KIAA1324	KIAA1324
chr15_-_24569201	1.284		GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3
chr12_-_43556424	1.282	NM_001145108 NM_006159	NELL2	NEL-like 2 (chicken)
chr6_+_96570565	1.278	NM_006581	FUT9	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr3_+_53504070	1.278	NM_000720 NM_001128839 NM_001128840	CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr19_+_3175734	1.274		CELF5	CUGBP, Elav-like family member 5
chr19_-_44503328	1.272
chr1_-_202921103	1.264	NM_006338 NM_201630	LRRN2	leucine rich repeat neuronal 2
chr10_-_88116181	1.262	NM_017551	GRID1	glutamate receptor, ionotropic, delta 1
chr15_-_51839129	1.261	NM_182758	WDR72	WD repeat domain 72
chr15_-_24569253	1.259		GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3
chr5_+_175231144	1.254		CPLX2	complexin 2
chr15_+_41597097	1.250	NM_002373	MAP1A	microtubule-associated protein 1A
chr12_+_84198015	1.239	NM_006982	ALX1	ALX homeobox 1
chr4_-_1156533	1.238	NM_012445	SPON2	spondin 2, extracellular matrix protein
chr20_+_21634515	1.232		PAX1	paired box 1
chr7_+_30917939	1.228	NM_198098	AQP1	aquaporin 1 (Colton blood group)
chr19_-_53706644	1.224
chr7_-_78920806	1.222	NM_012301	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr20_+_20296744	1.214	NM_002196	INSM1	insulinoma-associated 1
chr8_-_26427304	1.211	NM_007257	PNMA2	paraneoplastic antigen MA2
chr4_-_168392266	1.210		SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr17_+_1906262	1.202	NM_001098202	HIC1	hypermethylated in cancer 1
chr13_-_71339313	1.200	NM_004392 NM_080759 NM_080760	DACH1	dachshund homolog 1 (Drosophila)
chr17_+_26742767	1.192	NM_032932	RAB11FIP4	RAB11 family interacting protein 4 (class II)
chr8_+_26427378	1.184	NM_001197293	DPYSL2	dihydropyrimidinase-like 2
chr8_-_89408832	1.179	NM_005941	MMP16	matrix metallopeptidase 16 (membrane-inserted)
chr20_-_61462960	1.178	NM_000744	CHRNA4	cholinergic receptor, nicotinic, alpha 4
chr8_-_111056099	1.173	NM_014379	KCNV1	potassium channel, subfamily V, member 1
chr15_-_49174107	1.173		TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr2_-_144994349	1.167	NM_001171653 NM_014795	ZEB2	zinc finger E-box binding homeobox 2
chr12_-_43556220	1.167		NELL2	NEL-like 2 (chicken)
chr2_-_192767494	1.167		TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2
chr7_+_68702252	1.165		AUTS2	autism susceptibility candidate 2
chrX_+_104953187	1.165	NM_198465	NRK	Nik related kinase
chr20_-_55274497	1.165		BMP7	bone morphogenetic protein 7
chr1_-_37272295	1.163	NM_000831	GRIK3	glutamate receptor, ionotropic, kainate 3
chr2_+_176680251	1.162	NM_021192	HOXD11	homeobox D11
chr7_-_23476497	1.160	NM_006547	IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3
chr1_+_145479805	1.153	NM_004326	BCL9	B-cell CLL/lymphoma 9
chr5_+_170779664	1.151		FGF18	fibroblast growth factor 18
chr1_-_40555413	1.151		COL9A2	collagen, type IX, alpha 2
chr17_+_62391216	1.147	NM_014405	CACNG4	calcium channel, voltage-dependent, gamma subunit 4
chr4_-_5941043	1.145		CRMP1	collapsin response mediator protein 1
chr16_+_85101605	1.139	NM_001451	FOXF1	forkhead box F1
chr7_+_68702516	1.136		AUTS2	autism susceptibility candidate 2
chrX_+_104953215	1.133		NRK	Nik related kinase
chr2_-_200028977	1.132		SATB2	SATB homeobox 2
chr3_-_42282665	1.130	NM_000729	CCK	cholecystokinin
chr2_+_74594093	1.127		TLX2	T-cell leukemia homeobox 2
chr4_-_105635499	1.126		CXXC4	CXXC finger protein 4
chr4_-_46086528	1.122	NM_000807	GABRA2	gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr1_+_2975590	1.118	NM_022114 NM_199454	PRDM16	PR domain containing 16
chr2_+_176665694	1.114	NM_000523	HOXD13	homeobox D13
chr2_-_241408296	1.113	NM_004321	KIF1A	kinesin family member 1A
chr1_+_109458299	1.112		KIAA1324	KIAA1324
chr10_+_94823221	1.106	NM_057157	CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1
chr5_+_92944680	1.104	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr19_-_14177980	1.102	NM_001008701 NM_014921	LPHN1	latrophilin 1
chr1_-_175400441	1.102		ASTN1	astrotactin 1
chr3_-_159306532	1.101	NM_001163678 NM_003030 NM_006884	SHOX2	short stature homeobox 2
chrX_+_150095713	1.096	NM_004224	GPR50	G protein-coupled receptor 50
chr19_-_13478037	1.089	NM_000068 NM_001127221 NM_001127222 NM_001174080 NM_023035	CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr10_+_124885556	1.084	NM_001105574	HMX3	H6 family homeobox 3
chr9_-_129557373	1.078	NM_001142534 NM_001142533	SH2D3C	SH2 domain containing 3C
chr17_-_44058612	1.072	NM_024017	HOXB9	homeobox B9
chr2_-_227371698	1.067	NM_005544	IRS1	insulin receptor substrate 1
chr4_-_168392307	1.065	NM_001040159 NM_016950	SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr13_+_99432258	1.063	NM_007129	ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)
chr4_+_61749540	1.055		LPHN3	latrophilin 3
chr2_+_5750229	1.047	NM_003108	SOX11	SRY (sex determining region Y)-box 11
chr17_-_34014390	1.044		SRCIN1	SRC kinase signaling inhibitor 1
chr15_+_90738108	1.041	NM_006011	ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr5_+_175231098	1.040	NM_001008220	CPLX2	complexin 2
chr7_-_15692551	1.038		MEOX2	mesenchyme homeobox 2
chrX_-_137621492	1.037	NM_004114	FGF13	fibroblast growth factor 13
chr9_-_16860719	1.033	NM_017637	BNC2	basonuclin 2
chr6_-_33268177	1.029	NM_001163771 NM_080679 NM_080680 NM_080681	COL11A2	collagen, type XI, alpha 2
chr8_-_93177057	1.027	NM_001198625 NM_001198626 NM_001198627 NM_001198631 NM_001198634 NM_001198679	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_+_8440541	1.022		NXPH1	neurexophilin 1
chr19_-_40325194	1.020		LGI4	leucine-rich repeat LGI family, member 4
chr12_-_33483847	1.016	NM_198992	SYT10	synaptotagmin X
chr18_-_33399997	1.010	NM_001025087 NM_001025088 NM_001025089 NM_020180	CELF4	CUGBP, Elav-like family member 4
chr1_-_194844299	1.009		KCNT2	potassium channel, subfamily T, member 2
chr4_-_96689373	1.005	NM_003728	UNC5C	unc-5 homolog C (C. elegans)
chr4_+_7245218	1.005	NM_020777	SORCS2	sortilin-related VPS10 domain containing receptor 2
chr4_-_168392151	1.004		SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr19_+_51059357	1.003	NM_004497	FOXA3	forkhead box A3
chr12_+_56140184	1.000	NM_001160045 NM_001167609 NM_005269	GLI1	GLI family zinc finger 1
chr2_-_163403485	1.000	NM_033272 NM_173162	KCNH7	potassium voltage-gated channel, subfamily H (eag-related), member 7
chr1_+_168898898	0.996		PRRX1	paired related homeobox 1
chr6_+_69401660	0.994	NM_001704	BAI3	brain-specific angiogenesis inhibitor 3
chr18_+_53170718	0.994	NM_015879	ST8SIA3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr12_-_16650687	0.988		LMO3	LIM domain only 3 (rhombotin-like 2)
chr11_-_35398077	0.982	NM_001195728	SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr10_+_106390848	0.982	NM_014978	SORCS3	sortilin-related VPS10 domain containing receptor 3
chr16_+_85101734	0.981		FOXF1	forkhead box F1
chr15_-_75711785	0.980		LINGO1	leucine rich repeat and Ig domain containing 1
chr11_-_106394039	0.979	NM_000855	GUCY1A2	guanylate cyclase 1, soluble, alpha 2
chr3_+_3816079	0.978	NM_020873	LRRN1	leucine rich repeat neuronal 1
chr12_+_111980044	0.978	NM_004416	DTX1	deltex homolog 1 (Drosophila)
chr5_-_160907702	0.976	NM_000813 NM_021911	GABRB2	gamma-aminobutyric acid (GABA) A receptor, beta 2
chr17_-_47591123	0.973	NM_020178	CA10	carbonic anhydrase X
chrX_+_90920915	0.973	NM_032967	PCDH11X PCDH11Y	protocadherin 11 X-linked protocadherin 11 Y-linked
chr3_+_11009419	0.971	NM_003042	SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr3_-_135097111	0.967	NM_016577	RAB6B	RAB6B, member RAS oncogene family

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.18	2.18e-28	GO:0050789	regulation of biological process
1.18	6.05e-28	GO:0050794	regulation of cellular process
1.16	6.28e-27	GO:0065007	biological regulation
1.46	8.08e-24	GO:0007399	nervous system development
1.32	9.11e-24	GO:0048731	system development
1.27	1.45e-22	GO:0007275	multicellular organismal development
1.25	9.05e-22	GO:0032502	developmental process
1.25	1.76e-20	GO:0023052	signaling
1.53	1.72e-18	GO:0022008	neurogenesis
1.26	3.03e-18	GO:0048856	anatomical structure development
1.53	2.90e-17	GO:0048699	generation of neurons
1.32	5.48e-16	GO:0030154	cell differentiation
1.27	1.07e-15	GO:0048518	positive regulation of biological process
1.41	1.50e-15	GO:0051239	regulation of multicellular organismal process
1.31	3.86e-15	GO:0048869	cellular developmental process
1.08	1.06e-14	GO:0009987	cellular process
1.37	1.25e-14	GO:0009653	anatomical structure morphogenesis
1.55	1.66e-14	GO:0030182	neuron differentiation
1.28	1.93e-14	GO:0048519	negative regulation of biological process
1.23	2.45e-14	GO:0007165	signal transduction
1.75	1.82e-13	GO:0007420	brain development
1.62	5.09e-13	GO:0007417	central nervous system development
1.26	6.20e-13	GO:0048522	positive regulation of cellular process
1.28	1.22e-12	GO:0048523	negative regulation of cellular process
1.30	1.24e-12	GO:0048583	regulation of response to stimulus
1.30	1.64e-12	GO:0048513	organ development
1.61	1.86e-12	GO:0000904	cell morphogenesis involved in differentiation
1.45	2.32e-12	GO:0050793	regulation of developmental process
1.19	3.97e-12	GO:0051716	cellular response to stimulus
1.32	6.18e-12	GO:0023051	regulation of signaling
1.48	6.42e-12	GO:0007267	cell-cell signaling
1.40	1.25e-11	GO:0010646	regulation of cell communication
1.47	3.07e-11	GO:2000026	regulation of multicellular organismal development
1.54	5.20e-11	GO:0048666	neuron development
1.49	6.56e-11	GO:0045595	regulation of cell differentiation
1.62	8.08e-11	GO:0048667	cell morphogenesis involved in neuron differentiation
1.61	1.33e-10	GO:0048812	neuron projection morphogenesis
1.62	1.45e-10	GO:0007409	axonogenesis
1.57	2.13e-10	GO:0031175	neuron projection development
1.38	6.25e-10	GO:0007154	cell communication
1.14	8.25e-10	GO:0032501	multicellular organismal process
1.50	1.24e-09	GO:0000902	cell morphogenesis
1.91	3.97e-09	GO:0030900	forebrain development
1.52	1.90e-08	GO:0048858	cell projection morphogenesis
1.17	2.56e-08	GO:0031323	regulation of cellular metabolic process
1.51	2.58e-08	GO:0032990	cell part morphogenesis
1.55	2.69e-08	GO:0007268	synaptic transmission
1.37	2.80e-08	GO:0048468	cell development
1.46	4.05e-08	GO:0010629	negative regulation of gene expression
1.45	4.56e-08	GO:0032989	cellular component morphogenesis
1.16	4.65e-08	GO:0019222	regulation of metabolic process
1.51	4.87e-08	GO:0019226	transmission of nerve impulse
1.51	4.87e-08	GO:0035637	multicellular organismal signaling
1.65	5.01e-08	GO:0022603	regulation of anatomical structure morphogenesis
1.38	6.29e-08	GO:0040011	locomotion
1.29	6.93e-08	GO:0009966	regulation of signal transduction
1.64	7.08e-08	GO:0060284	regulation of cell development
1.21	8.60e-08	GO:0010468	regulation of gene expression
1.25	1.11e-07	GO:0007166	cell surface receptor linked signaling pathway
1.43	2.42e-07	GO:0030030	cell projection organization
1.17	2.79e-07	GO:0080090	regulation of primary metabolic process
1.47	3.24e-07	GO:0045892	negative regulation of transcription, DNA-dependent
1.34	3.86e-07	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.34	4.52e-07	GO:0032879	regulation of localization
1.19	5.34e-07	GO:0051171	regulation of nitrogen compound metabolic process
1.16	5.85e-07	GO:0051179	localization
1.85	6.53e-07	GO:0006813	potassium ion transport
1.59	6.88e-07	GO:0007411	axon guidance
1.19	7.39e-07	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17	8.03e-07	GO:0060255	regulation of macromolecule metabolic process
1.46	8.44e-07	GO:0051253	negative regulation of RNA metabolic process
1.50	8.60e-07	GO:0051094	positive regulation of developmental process
1.58	9.13e-07	GO:0045597	positive regulation of cell differentiation
1.43	9.74e-07	GO:0009887	organ morphogenesis
1.33	1.80e-06	GO:0042127	regulation of cell proliferation
1.39	2.26e-06	GO:0009790	embryo development
1.41	3.00e-06	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.18	4.42e-06	GO:0031326	regulation of cellular biosynthetic process
1.72	5.53e-06	GO:0045664	regulation of neuron differentiation
1.39	7.37e-06	GO:0007167	enzyme linked receptor protein signaling pathway
1.18	1.19e-05	GO:0009889	regulation of biosynthetic process
1.38	1.20e-05	GO:0031327	negative regulation of cellular biosynthetic process
1.40	1.25e-05	GO:0051172	negative regulation of nitrogen compound metabolic process
1.38	1.50e-05	GO:0010558	negative regulation of macromolecule biosynthetic process
1.59	1.60e-05	GO:0051960	regulation of nervous system development
1.40	1.71e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34	1.81e-05	GO:0051128	regulation of cellular component organization
2.02	2.04e-05	GO:0021537	telencephalon development
1.30	2.26e-05	GO:0009605	response to external stimulus
1.37	2.51e-05	GO:0009890	negative regulation of biosynthetic process
1.32	3.04e-05	GO:0006811	ion transport
1.37	3.30e-05	GO:0010628	positive regulation of gene expression
1.19	3.82e-05	GO:0051252	regulation of RNA metabolic process
1.47	7.27e-05	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.18	7.49e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.41	1.01e-04	GO:0006935	chemotaxis
1.41	1.01e-04	GO:0042330	taxis
1.33	1.09e-04	GO:0051173	positive regulation of nitrogen compound metabolic process
1.50	1.22e-04	GO:0007389	pattern specification process
1.81	1.52e-04	GO:0022604	regulation of cell morphogenesis
1.30	1.74e-04	GO:0006351	transcription, DNA-dependent
1.10	1.82e-04	GO:0050896	response to stimulus
1.58	1.83e-04	GO:0050767	regulation of neurogenesis
1.34	1.87e-04	GO:0051049	regulation of transport
1.50	2.13e-04	GO:0044057	regulation of system process
1.18	2.23e-04	GO:0006355	regulation of transcription, DNA-dependent
1.17	2.33e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.29	2.60e-04	GO:0010605	negative regulation of macromolecule metabolic process
1.25	2.68e-04	GO:0009893	positive regulation of metabolic process
1.80	2.79e-04	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.26	3.18e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.40	3.32e-04	GO:0048585	negative regulation of response to stimulus
1.44	4.19e-04	GO:0009968	negative regulation of signal transduction
1.43	4.46e-04	GO:0016477	cell migration
1.42	5.30e-04	GO:0032583	regulation of gene-specific transcription
1.72	5.50e-04	GO:0031344	regulation of cell projection organization
1.30	6.29e-04	GO:0031328	positive regulation of cellular biosynthetic process
1.31	6.41e-04	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15	6.90e-04	GO:0051234	establishment of localization
1.56	8.35e-04	GO:0003002	regionalization
1.77	9.20e-04	GO:0010975	regulation of neuron projection development
1.24	9.60e-04	GO:0031325	positive regulation of cellular metabolic process
1.17	1.00e-03	GO:0065008	regulation of biological quality
1.56	1.01e-03	GO:0048568	embryonic organ development
1.48	1.15e-03	GO:0001501	skeletal system development
1.37	1.19e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
2.38	1.32e-03	GO:0021987	cerebral cortex development
1.84	1.32e-03	GO:0010720	positive regulation of cell development
1.49	1.37e-03	GO:0051130	positive regulation of cellular component organization
1.40	1.39e-03	GO:0023057	negative regulation of signaling
1.28	1.61e-03	GO:0009891	positive regulation of biosynthetic process
1.34	1.62e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.40	1.68e-03	GO:0010648	negative regulation of cell communication
1.25	1.76e-03	GO:0010941	regulation of cell death
1.26	1.88e-03	GO:0009892	negative regulation of metabolic process
1.14	1.94e-03	GO:0006810	transport
1.38	1.98e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.29	2.22e-03	GO:0048584	positive regulation of response to stimulus
1.32	2.31e-03	GO:0051254	positive regulation of RNA metabolic process
1.30	2.33e-03	GO:0010557	positive regulation of macromolecule biosynthetic process
1.50	2.33e-03	GO:0035295	tube development
1.36	2.46e-03	GO:0010647	positive regulation of cell communication
1.36	2.49e-03	GO:0023056	positive regulation of signaling
1.43	2.49e-03	GO:0048598	embryonic morphogenesis
1.99	2.87e-03	GO:0050770	regulation of axonogenesis
1.45	3.47e-03	GO:0051093	negative regulation of developmental process
1.45	3.73e-03	GO:0015672	monovalent inorganic cation transport
1.26	5.45e-03	GO:0031324	negative regulation of cellular metabolic process
1.89	5.95e-03	GO:0055123	digestive system development
1.24	6.20e-03	GO:0042981	regulation of apoptosis
1.24	7.61e-03	GO:0043067	regulation of programmed cell death
1.37	8.64e-03	GO:0048870	cell motility
1.37	8.64e-03	GO:0051674	localization of cell
1.38	9.07e-03	GO:0060341	regulation of cellular localization
1.64	9.16e-03	GO:0045165	cell fate commitment
1.25	9.43e-03	GO:0032774	RNA biosynthetic process
1.40	9.53e-03	GO:0009792	embryo development ending in birth or egg hatching
1.12	1.10e-02	GO:0016043	cellular component organization
1.15	1.17e-02	GO:0042221	response to chemical stimulus
1.35	1.25e-02	GO:0072358	cardiovascular system development
1.35	1.25e-02	GO:0072359	circulatory system development
1.91	1.55e-02	GO:0031346	positive regulation of cell projection organization
1.91	1.55e-02	GO:0048638	regulation of developmental growth
1.47	1.58e-02	GO:0045596	negative regulation of cell differentiation
2.02	1.68e-02	GO:0021543	pallium development
1.32	1.97e-02	GO:0006928	cellular component movement
1.33	2.15e-02	GO:0009967	positive regulation of signal transduction
1.39	2.27e-02	GO:0043009	chordate embryonic development
1.36	2.42e-02	GO:0008285	negative regulation of cell proliferation
1.89	2.47e-02	GO:0048565	digestive tract development
1.39	3.15e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.33	3.33e-02	GO:0030001	metal ion transport
1.90	3.64e-02	GO:0009953	dorsal/ventral pattern formation
1.41	4.14e-02	GO:0051050	positive regulation of transport
1.90	4.41e-02	GO:0030902	hindbrain development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.72	1.27e-15	GO:0045202	synapse
1.26	1.06e-12	GO:0044459	plasma membrane part
1.76	1.81e-12	GO:0044456	synapse part
1.60	1.66e-10	GO:0043005	neuron projection
1.29	4.02e-08	GO:0031226	intrinsic to plasma membrane
1.72	1.31e-07	GO:0034702	ion channel complex
1.28	1.90e-07	GO:0005887	integral to plasma membrane
1.86	8.27e-07	GO:0034703	cation channel complex
1.69	3.35e-06	GO:0030425	dendrite
1.30	1.21e-05	GO:0042995	cell projection
1.46	1.86e-05	GO:0031012	extracellular matrix
2.51	3.23e-05	GO:0042734	presynaptic membrane
1.36	3.49e-05	GO:0030054	cell junction
1.67	4.80e-05	GO:0043025	neuronal cell body
1.64	1.02e-04	GO:0044297	cell body
1.99	1.19e-04	GO:0033267	axon part
1.69	1.29e-04	GO:0045211	postsynaptic membrane
1.63	1.40e-04	GO:0030424	axon
1.46	2.34e-04	GO:0005578	proteinaceous extracellular matrix
1.89	2.49e-04	GO:0008076	voltage-gated potassium channel complex
1.89	2.49e-04	GO:0034705	potassium channel complex
1.91	5.34e-04	GO:0014069	postsynaptic density
1.11	6.64e-04	GO:0005886	plasma membrane
1.11	9.70e-04	GO:0071944	cell periphery
1.39	1.57e-03	GO:0009986	cell surface
1.02	6.27e-03	GO:0005623	cell
1.02	7.38e-03	GO:0044464	cell part
1.24	1.92e-02	GO:0031988	membrane-bounded vesicle
1.23	2.46e-02	GO:0031410	cytoplasmic vesicle
1.23	3.15e-02	GO:0031982	vesicle
1.61	3.52e-02	GO:0044420	extracellular matrix part
1.24	3.56e-02	GO:0016023	cytoplasmic membrane-bounded vesicle
1.48	3.77e-02	GO:0031252	cell leading edge
2.91	3.87e-02	GO:0008328	ionotropic glutamate receptor complex
1.45	3.88e-02	GO:0030135	coated vesicle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.58	1.45e-17	GO:0043565	sequence-specific DNA binding
1.43	1.55e-14	GO:0030528	transcription regulator activity
1.42	1.39e-13	GO:0001071	nucleic acid binding transcription factor activity
1.42	1.39e-13	GO:0003700	sequence-specific DNA binding transcription factor activity
1.12	1.54e-12	GO:0005515	protein binding
1.72	1.40e-11	GO:0022836	gated channel activity
1.76	5.50e-11	GO:0005261	cation channel activity
1.62	5.82e-11	GO:0005216	ion channel activity
1.60	3.44e-10	GO:0022838	substrate-specific channel activity
1.58	4.92e-10	GO:0015267	channel activity
1.58	6.51e-10	GO:0022803	passive transmembrane transporter activity
1.84	3.45e-09	GO:0005244	voltage-gated ion channel activity
1.84	3.45e-09	GO:0022832	voltage-gated channel activity
1.64	3.90e-09	GO:0016563	transcription activator activity
1.93	1.60e-08	GO:0022843	voltage-gated cation channel activity
1.46	1.87e-08	GO:0008324	cation transmembrane transporter activity
1.05	1.52e-07	GO:0005488	binding
1.38	1.94e-07	GO:0015075	ion transmembrane transporter activity
1.88	2.15e-06	GO:0005267	potassium channel activity
1.32	2.51e-06	GO:0022891	substrate-specific transmembrane transporter activity
1.29	4.25e-05	GO:0022857	transmembrane transporter activity
1.42	5.70e-05	GO:0019904	protein domain specific binding
1.89	9.40e-05	GO:0005249	voltage-gated potassium channel activity
1.26	1.54e-04	GO:0022892	substrate-specific transporter activity
1.23	6.31e-04	GO:0005215	transporter activity
1.29	9.21e-04	GO:0019899	enzyme binding
2.58	9.35e-04	GO:0008066	glutamate receptor activity
1.70	1.56e-03	GO:0015276	ligand-gated ion channel activity
1.70	1.56e-03	GO:0022834	ligand-gated channel activity
1.15	2.64e-03	GO:0003677	DNA binding
2.86	3.94e-03	GO:0005234	extracellular-glutamate-gated ion channel activity
2.83	1.13e-02	GO:0004970	ionotropic glutamate receptor activity
3.15	1.53e-02	GO:0043548	phosphatidylinositol 3-kinase binding
1.25	2.43e-02	GO:0042802	identical protein binding
1.38	2.76e-02	GO:0016564	transcription repressor activity
1.26	3.08e-02	GO:0005509	calcium ion binding

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