Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 2.147


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
UBTFchr17_-_396524490.601.3e-02Click!
SSRP1chr11_-_56859900-0.361.7e-01Click!
HBP1chr7_+_106596641-0.273.2e-01Click!
HMGB3chrX_+_1499024150.243.6e-01Click!
HMGB2chr4_-_1744920290.136.4e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_105511615 7.221 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr14_-_56342097 5.730 NM_172337
OTX2
orthodenticle homeobox 2
chr12_-_16649211 5.665 LMO3
LIM domain only 3 (rhombotin-like 2)
chr13_-_52320774 5.254 NM_002590
NM_032949
PCDH8

protocadherin 8

chr11_-_16380967 5.068 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr8_-_72436519 4.811 EYA1
eyes absent homolog 1 (Drosophila)
chr5_+_170668892 4.438 NM_021025
TLX3
T-cell leukemia homeobox 3
chr14_+_36196523 4.071 NM_006194
PAX9
paired box 9
chr2_-_200033445 3.998 SATB2
SATB homeobox 2
chr5_-_88004891 3.938 LOC645323
hypothetical LOC645323
chr18_+_3441589 3.641 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr4_-_101658094 3.465 NM_001159694
NM_016242
EMCN

endomucin

chr5_-_44424423 3.426 NM_004465
FGF10
fibroblast growth factor 10
chr9_-_23816062 3.389 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr13_+_99431417 3.246


chr15_-_48198697 3.045 NM_024837
ATP8B4
ATPase, class I, type 8B, member 4
chr2_+_12775814 3.003


chr6_-_128883125 2.916 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr1_-_102234959 2.798 OLFM3
olfactomedin 3
chr18_-_28606839 2.707 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr15_+_64781723 2.639 NM_005585
SMAD6
SMAD family member 6
chr8_-_72437020 2.615 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr15_+_47502666 2.586 NM_002009
FGF7
fibroblast growth factor 7
chr3_+_2117246 2.520 NM_175607
CNTN4
contactin 4
chr12_-_16652202 2.477 NM_001001395
LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_-_20594645 2.379 KCNIP4
Kv channel interacting protein 4
chr2_-_208697441 2.350 NM_006891
CRYGD
crystallin, gamma D
chrX_+_77889861 2.302 NM_005296
LPAR4
lysophosphatidic acid receptor 4
chr17_-_44058612 2.246 NM_024017
HOXB9
homeobox B9
chrX_+_99726445 2.219 NM_022144
TNMD
tenomodulin
chr1_-_150353179 2.167 NM_007113
TCHH
trichohyalin
chr6_-_94185780 2.167 NM_004440
EPHA7
EPH receptor A7
chr3_-_48675321 2.163 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr1_+_81544432 2.118 LPHN2
latrophilin 2
chr8_-_72436832 2.060 EYA1
eyes absent homolog 1 (Drosophila)
chr4_+_54790190 2.047 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr3_+_89239494 1.985 EPHA3
EPH receptor A3
chr17_-_35017650 1.983 NEUROD2
neurogenic differentiation 2
chr2_+_171280046 1.938 NM_001003845
SP5
Sp5 transcription factor
chr1_+_85819004 1.924 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chrX_+_115215985 1.880 NM_000686
AGTR2
angiotensin II receptor, type 2
chr18_-_29412148 1.860


chr20_+_20296744 1.853 NM_002196
INSM1
insulinoma-associated 1
chr11_+_112337199 1.837 NM_000615
NM_001076682
NM_181351
NCAM1


neural cell adhesion molecule 1


chr2_-_100088691 1.824 AFF3
AF4/FMR2 family, member 3
chr2_-_213111525 1.820 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr20_-_3097070 1.806 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr13_-_83354474 1.795 NM_052910
SLITRK1
SLIT and NTRK-like family, member 1
chr15_+_45797977 1.794 NM_020858
NM_024966
NM_153616
NM_153617
NM_153618
NM_153619
SEMA6D





sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D





chr3_-_55496370 1.793 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr1_-_50661716 1.776 NM_032110
DMRTA2
DMRT-like family A2
chr4_+_119174947 1.771 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr5_+_140181405 1.737 NM_018908
NM_031501
PCDHA5

protocadherin alpha 5

chr7_-_83662152 1.714 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr14_+_76298693 1.687 VASH1
vasohibin 1
chr12_-_16650697 1.668 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_+_123062143 1.655 STAG2
stromal antigen 2
chr12_-_16650687 1.638 LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_-_111777651 1.629 PITX2
paired-like homeodomain 2
chr10_-_118887801 1.607 NM_001112704
NM_199131
VAX1

ventral anterior homeobox 1

chr2_-_72228427 1.606 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr20_-_21326046 1.605 NM_033176
NKX2-4
NK2 homeobox 4
chr1_-_49014993 1.597 NM_024603
BEND5
BEN domain containing 5
chr5_+_140777454 1.584 NM_018927
NM_032101
PCDHGB7

protocadherin gamma subfamily B, 7

chr8_+_85258257 1.580 RALYL
RALY RNA binding protein-like
chr5_-_11956964 1.567 NM_001332
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr4_-_138673078 1.567 NM_019035
PCDH18
protocadherin 18
chr3_+_89239363 1.564 NM_005233
NM_182644
EPHA3

EPH receptor A3

chr19_+_12810258 1.562 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr2_+_101680594 1.559 NM_004834
NM_145686
NM_145687
MAP4K4


mitogen-activated protein kinase kinase kinase kinase 4


chr4_-_73653331 1.554 NM_014243
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr2_+_12775336 1.552 TRIB2
tribbles homolog 2 (Drosophila)
chr19_-_61876057 1.551 NM_001005850
ZNF835
zinc finger protein 835
chr3_-_65999548 1.521 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr10_-_123346148 1.520 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr2_+_143603439 1.511 ARHGAP15
Rho GTPase activating protein 15
chr17_+_35471971 1.500 NM_001190919
THRA
thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
chr13_-_83354425 1.496 SLITRK1
SLIT and NTRK-like family, member 1
chr21_-_31853160 1.491 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr20_+_71230 1.485 NM_030931
DEFB126
defensin, beta 126
chr2_-_100088760 1.485 AFF3
AF4/FMR2 family, member 3
chr18_+_29412538 1.483 NM_030632
ASXL3
additional sex combs like 3 (Drosophila)
chr4_-_184480572 1.472 NM_001185149
CLDN24
claudin 24
chr2_+_149349643 1.467


chr1_-_152431175 1.465 NM_152263
TPM3
tropomyosin 3
chr5_-_76970264 1.462 NM_032109
OTP
orthopedia homeobox
chr5_+_147238466 1.445 NM_054023
SCGB3A2
secretoglobin, family 3A, member 2
chr1_-_149955870 1.444 NM_007185
CELF3
CUGBP, Elav-like family member 3
chr7_-_150737980 1.438 NM_198285
WDR86
WD repeat domain 86
chrX_-_33267646 1.430 NM_000109
DMD
dystrophin
chr4_-_155632317 1.426 NM_001142552
NM_001142553
DCHS2

dachsous 2 (Drosophila)

chr8_+_104900591 1.397 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr6_-_134680888 1.393 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr5_-_22889487 1.392 NM_004061
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr9_+_117955890 1.383 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr3_+_148593911 1.374


chr4_+_183302105 1.367 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr12_-_23995109 1.363 SOX5
SRY (sex determining region Y)-box 5
chr6_-_64087806 1.356 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr4_-_155631861 1.351 DCHS2
dachsous 2 (Drosophila)
chr11_+_101488380 1.349 NM_001195045
YAP1
Yes-associated protein 1
chr5_-_83715947 1.344 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr4_+_81337663 1.336 NM_001099403
PRDM8
PR domain containing 8
chr19_+_12995782 1.323 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr14_-_36058648 1.315 NM_003317
NKX2-1
NK2 homeobox 1
chr18_-_30056431 1.313 NM_001198547
NOL4
nucleolar protein 4
chr10_+_11246934 1.312 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr6_-_134540666 1.306 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr13_-_98428244 1.296 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr10_+_70517823 1.270 NM_002727
SRGN
serglycin
chr5_+_15553736 1.266 FBXL7
F-box and leucine-rich repeat protein 7
chr1_-_155095289 1.264 NM_014215
INSRR
insulin receptor-related receptor
chr9_-_16717887 1.263 BNC2
basonuclin 2
chr9_-_14304036 1.262 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr5_+_98132898 1.247 NM_001012761
RGMB
RGM domain family, member B
chr12_+_83954229 1.246 NM_001079910
NM_032165
LRRIQ1

leucine-rich repeats and IQ motif containing 1

chr19_+_11510578 1.244 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr2_-_162808123 1.237 NM_004460
FAP
fibroblast activation protein, alpha
chr12_-_8584658 1.233 NM_014358
CLEC4E
C-type lectin domain family 4, member E
chr10_+_70517863 1.231 SRGN
serglycin
chr8_+_85258007 1.224 NM_001100392
NM_001100393
RALYL

RALY RNA binding protein-like

chr5_-_83716346 1.222 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chrX_+_28515479 1.211 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr3_-_55496607 1.210 WNT5A
wingless-type MMTV integration site family, member 5A
chr10_+_111957292 1.210 NM_130439
MXI1
MAX interactor 1
chr2_-_165768798 1.201 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr11_-_31789431 1.200 NM_000280
NM_001604
PAX6

paired box 6

chr15_+_58083712 1.197 NM_012182
FOXB1
forkhead box B1
chr13_+_96592051 1.197 MBNL2
muscleblind-like 2 (Drosophila)
chr7_+_28418668 1.195 NM_182898
CREB5
cAMP responsive element binding protein 5
chr11_-_31789334 1.189 PAX6
paired box 6
chr14_+_76297885 1.185 NM_014909
VASH1
vasohibin 1
chr9_-_94338072 1.184 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr11_-_31789360 1.176 PAX6
paired box 6
chr8_+_85258056 1.163 NM_173848
RALYL
RALY RNA binding protein-like
chr12_-_83954185 1.158 NM_001100917
TSPAN19
tetraspanin 19
chr4_+_86918882 1.157 ARHGAP24
Rho GTPase activating protein 24
chr1_-_238842071 1.156 NM_022469
GREM2
gremlin 2
chr13_+_107753764 1.152


chr1_-_214963279 1.146 NM_001438
ESRRG
estrogen-related receptor gamma
chr11_-_31789168 1.145 PAX6
paired box 6
chr12_-_23995220 1.145 SOX5
SRY (sex determining region Y)-box 5
chr2_+_104837004 1.145


chrX_-_131401319 1.143 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr12_-_60872814 1.142 NM_178539
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr1_-_215377718 1.141 NM_001134285
ESRRG
estrogen-related receptor gamma
chr13_+_51334117 1.140 NM_031290
CCDC70
coiled-coil domain containing 70
chrX_+_152562013 1.137 DUSP9
dual specificity phosphatase 9
chr2_+_143603368 1.137 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr15_+_74416156 1.135 NM_145805
ISL2
ISL LIM homeobox 2
chr8_+_70567634 1.133 SULF1
sulfatase 1
chr4_+_52612197 1.132 NM_145263
SPATA18
spermatogenesis associated 18 homolog (rat)
chr4_-_64957595 1.132 NM_001010874
TECRL
trans-2,3-enoyl-CoA reductase-like
chr11_-_114880275 1.131 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr11_+_131285747 1.124 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr11_-_20138445 1.122 NM_001029865
DBX1
developing brain homeobox 1
chr14_-_59167193 1.122 NM_206852
RTN1
reticulon 1
chr2_+_185171682 1.119 ZNF804A
zinc finger protein 804A
chr17_+_56843893 1.114 NM_203425
C17orf82
chromosome 17 open reading frame 82
chr12_-_88270375 1.113 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr9_+_126460511 1.109


chr8_-_87824996 1.105 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chr11_+_131286513 1.102 NTM
neurotrimin
chr7_+_113842284 1.102 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chrX_-_10605726 1.095 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chrX_-_142551587 1.094 NM_001184749
SLITRK4
SLIT and NTRK-like family, member 4
chr12_-_7487989 1.084 NM_174941
CD163L1
CD163 molecule-like 1
chr6_+_50894397 1.082 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr5_-_76970129 1.081 OTP
orthopedia homeobox
chr4_+_170817787 1.067 CLCN3
chloride channel 3
chr11_+_22316242 1.060 NM_020346
SLC17A6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr2_+_171280182 1.060


chr5_-_22889192 1.056 CDH12
cadherin 12, type 2 (N-cadherin 2)
chr5_-_147142457 1.056 JAKMIP2
janus kinase and microtubule interacting protein 2
chr8_+_102574012 1.051 GRHL2
grainyhead-like 2 (Drosophila)
chr1_+_219119430 1.050 HLX
H2.0-like homeobox
chr17_+_71095733 1.049 MYO15B
myosin XVB pseudogene
chr5_-_134899537 1.038 NM_006161
NEUROG1
neurogenin 1
chr17_-_35017691 1.036 NM_006160
NEUROD2
neurogenic differentiation 2
chr13_-_78075683 1.033 NM_006237
POU4F1
POU class 4 homeobox 1
chr7_-_11838260 1.032 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr3_+_182912405 1.032 NM_003106
SOX2
SRY (sex determining region Y)-box 2
chr7_+_28415495 1.031 LOC401317
hypothetical LOC401317
chr1_-_102235377 1.029 NM_058170
OLFM3
olfactomedin 3
chrX_-_116991728 1.025 NM_033495
NM_001168300
KLHL13

kelch-like 13 (Drosophila)

chr12_-_98072602 1.019 NM_020140
NM_181670
ANKS1B

ankyrin repeat and sterile alpha motif domain containing 1B

chr7_+_18501876 1.018 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr14_+_36200867 1.016 PAX9
paired box 9
chrX_-_138114100 1.015 FGF13
fibroblast growth factor 13
chr9_+_102830851 1.014 NM_207299
LPPR1
lipid phosphate phosphatase-related protein type 1
chr4_-_111777584 1.011 PITX2
paired-like homeodomain 2
chr13_-_37341859 1.009 NM_001135955
NM_001135956
NM_001135957
NM_001135958
NM_003306
NM_016179
TRPC4





transient receptor potential cation channel, subfamily C, member 4





chr11_-_102219450 1.007 NM_002422
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr7_-_19123765 1.007 TWIST1
twist homolog 1 (Drosophila)
chr17_-_76985538 1.000


chr9_+_27099138 0.988 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr6_+_154373323 0.985 NM_001145279
NM_001145280
NM_001145281
OPRM1


opioid receptor, mu 1


chr3_+_116824840 0.983 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr4_-_165523856 0.981 NM_001166373
MARCH1
membrane-associated ring finger (C3HC4) 1
chr8_-_114518194 0.979 NM_052900
NM_198123
CSMD3

CUB and Sushi multiple domains 3


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.34 1.65e-22 GO:0032501 multicellular organismal process
1.44 1.40e-21 GO:0007275 multicellular organismal development
1.42 1.82e-21 GO:0032502 developmental process
1.47 4.88e-19 GO:0048731 system development
1.69 1.91e-18 GO:0007399 nervous system development
1.43 2.47e-18 GO:0048856 anatomical structure development
1.47 3.48e-12 GO:0030154 cell differentiation
1.46 4.15e-12 GO:0048869 cellular developmental process
1.53 9.33e-11 GO:0009653 anatomical structure morphogenesis
1.71 9.45e-09 GO:0007155 cell adhesion
1.71 9.45e-09 GO:0022610 biological adhesion
1.42 1.17e-08 GO:0048513 organ development
2.13 5.83e-08 GO:0016337 cell-cell adhesion
2.72 6.87e-08 GO:0007156 homophilic cell adhesion
1.63 9.89e-08 GO:0048699 generation of neurons
1.61 1.02e-07 GO:0022008 neurogenesis
2.21 6.39e-07 GO:0003002 regionalization
1.78 1.53e-06 GO:0007417 central nervous system development
1.65 2.10e-06 GO:0030182 neuron differentiation
1.95 2.96e-06 GO:0007389 pattern specification process
1.70 3.92e-06 GO:0009887 organ morphogenesis
1.31 9.99e-06 GO:0048519 negative regulation of biological process
1.87 1.26e-05 GO:0048598 embryonic morphogenesis
1.33 1.69e-05 GO:0048523 negative regulation of cellular process
1.59 1.97e-05 GO:2000026 regulation of multicellular organismal development
1.61 2.37e-05 GO:0009790 embryo development
1.53 3.18e-05 GO:0006351 transcription, DNA-dependent
1.51 4.50e-05 GO:0048468 cell development
1.15 9.29e-05 GO:0050896 response to stimulus
2.26 1.05e-04 GO:0009952 anterior/posterior pattern formation
1.80 2.27e-04 GO:0007420 brain development
1.79 2.29e-04 GO:0009792 embryo development ending in birth or egg hatching
1.67 2.77e-04 GO:0000904 cell morphogenesis involved in differentiation
1.78 2.80e-04 GO:0043009 chordate embryonic development
1.59 3.13e-04 GO:0032989 cellular component morphogenesis
1.71 3.52e-04 GO:0023057 negative regulation of signaling
1.70 3.98e-04 GO:0010648 negative regulation of cell communication
1.59 5.32e-04 GO:0000902 cell morphogenesis
1.46 8.47e-04 GO:0050793 regulation of developmental process
1.44 1.10e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.65 1.13e-03 GO:0072358 cardiovascular system development
1.65 1.13e-03 GO:0072359 circulatory system development
1.53 1.26e-03 GO:0045595 regulation of cell differentiation
1.65 1.26e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.62 1.56e-03 GO:0048585 negative regulation of response to stimulus
1.56 1.62e-03 GO:0045893 positive regulation of transcription, DNA-dependent
2.63 2.29e-03 GO:0048706 embryonic skeletal system development
1.21 2.31e-03 GO:0007165 signal transduction
1.68 2.47e-03 GO:0009968 negative regulation of signal transduction
1.42 3.09e-03 GO:0032774 RNA biosynthetic process
1.45 3.18e-03 GO:0009888 tissue development
1.49 3.24e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
2.14 4.00e-03 GO:0045165 cell fate commitment
2.60 4.59e-03 GO:0021953 central nervous system neuron differentiation
1.23 4.63e-03 GO:0048518 positive regulation of biological process
3.20 4.64e-03 GO:0048663 neuron fate commitment
1.19 4.84e-03 GO:0023052 signaling
1.64 5.37e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
2.33 5.59e-03 GO:0048736 appendage development
2.33 5.59e-03 GO:0060173 limb development
1.30 5.70e-03 GO:0003008 system process
2.35 6.57e-03 GO:0035107 appendage morphogenesis
2.35 6.57e-03 GO:0035108 limb morphogenesis
2.02 6.97e-03 GO:0030900 forebrain development
2.50 7.13e-03 GO:0051271 negative regulation of cellular component movement
1.44 7.42e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.74 7.44e-03 GO:0060284 regulation of cell development
1.50 7.54e-03 GO:0010628 positive regulation of gene expression
1.50 7.58e-03 GO:0051254 positive regulation of RNA metabolic process
1.64 7.71e-03 GO:0007409 axonogenesis
1.35 8.15e-03 GO:0051239 regulation of multicellular organismal process
1.50 8.39e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.74 8.45e-03 GO:0001501 skeletal system development
1.43 9.57e-03 GO:0040011 locomotion
2.25 1.40e-02 GO:0043583 ear development
1.45 1.42e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.04 1.53e-02 GO:0048562 embryonic organ morphogenesis
1.71 1.58e-02 GO:0051093 negative regulation of developmental process
1.79 1.70e-02 GO:0045596 negative regulation of cell differentiation
1.44 1.72e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
2.14 1.88e-02 GO:0048705 skeletal system morphogenesis
1.42 1.96e-02 GO:0009891 positive regulation of biosynthetic process
1.54 2.10e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.23 2.46e-02 GO:0048522 positive regulation of cellular process
1.75 2.52e-02 GO:0035295 tube development
1.60 3.22e-02 GO:0016477 cell migration
1.31 3.43e-02 GO:0050877 neurological system process
2.41 3.53e-02 GO:0021915 neural tube development
1.50 3.57e-02 GO:0048666 neuron development
1.57 3.75e-02 GO:0048812 neuron projection morphogenesis
1.63 4.18e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.79 4.99e-02 GO:0048568 embryonic organ development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.21 5.12e-06 GO:0005886 plasma membrane
1.20 7.01e-06 GO:0071944 cell periphery
1.55 2.25e-04 GO:0030054 cell junction
1.75 4.96e-04 GO:0005578 proteinaceous extracellular matrix
2.23 1.63e-03 GO:0044420 extracellular matrix part
1.64 1.81e-03 GO:0031012 extracellular matrix
1.32 3.47e-02 GO:0044421 extracellular region part
2.33 4.08e-02 GO:0005604 basement membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.64 5.99e-11 GO:0001071 nucleic acid binding transcription factor activity
1.64 5.99e-11 GO:0003700 sequence-specific DNA binding transcription factor activity
1.77 1.67e-10 GO:0043565 sequence-specific DNA binding
1.62 2.30e-10 GO:0030528 transcription regulator activity
1.77 3.86e-04 GO:0016563 transcription activator activity
1.51 5.67e-04 GO:0005509 calcium ion binding
2.97 7.79e-03 GO:0008013 beta-catenin binding
2.38 1.09e-02 GO:0019199 transmembrane receptor protein kinase activity