Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 2.147


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
UBTFchr17_-_396524490.601.3e-02Click!
SSRP1chr11_-_56859900-0.361.7e-01Click!
HBP1chr7_+_106596641-0.273.2e-01Click!
HMGB3chrX_+_1499024150.243.6e-01Click!
HMGB2chr4_-_1744920290.136.4e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_105511615 7.221 NM_001004317
 LIN28B
lin-28 homolog B (C. elegans)
chr14_-_56342097 5.730 NM_172337
 OTX2
orthodenticle homeobox 2
chr12_-_16649211 5.665 LMO3
LIM domain only 3 (rhombotin-like 2)
chr13_-_52320774 5.254 NM_002590
NM_032949
 PCDH8

protocadherin 8

chr11_-_16380967 5.068 NM_001145819
NM_017508
 SOX6

SRY (sex determining region Y)-box 6

chr8_-_72436519 4.811 EYA1
eyes absent homolog 1 (Drosophila)
chr5_+_170668892 4.438 NM_021025
 TLX3
T-cell leukemia homeobox 3
chr14_+_36196523 4.071 NM_006194
 PAX9
paired box 9
chr2_-_200033445 3.998 SATB2
SATB homeobox 2
chr5_-_88004891 3.938 LOC645323
hypothetical LOC645323
chr18_+_3441589 3.641 NM_170695
NM_173210
 TGIF1

TGFB-induced factor homeobox 1

chr4_-_101658094 3.465 NM_001159694
NM_016242
 EMCN

endomucin

chr5_-_44424423 3.426 NM_004465
 FGF10
fibroblast growth factor 10
chr9_-_23816062 3.389 NM_004432
 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr13_+_99431417 3.246


chr15_-_48198697 3.045 NM_024837
 ATP8B4
ATPase, class I, type 8B, member 4
chr2_+_12775814 3.003


chr6_-_128883125 2.916 NM_002844
NM_001135648
 PTPRK

protein tyrosine phosphatase, receptor type, K

chr1_-_102234959 2.798 OLFM3
olfactomedin 3
chr18_-_28606839 2.707 NM_020805
 KLHL14
kelch-like 14 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 92 entries
enrichment   p-value GO term description
3.20 4.64e-03 GO:0048663 neuron fate commitment
2.72 6.87e-08 GO:0007156 homophilic cell adhesion
2.63 2.29e-03 GO:0048706 embryonic skeletal system development
2.60 4.59e-03 GO:0021953 central nervous system neuron differentiation
2.50 7.13e-03 GO:0051271 negative regulation of cellular component movement
2.41 3.53e-02 GO:0021915 neural tube development
2.35 6.57e-03 GO:0035107 appendage morphogenesis
2.35 6.57e-03 GO:0035108 limb morphogenesis
2.33 5.59e-03 GO:0048736 appendage development
2.33 5.59e-03 GO:0060173 limb development
2.26 1.05e-04 GO:0009952 anterior/posterior pattern formation
2.25 1.40e-02 GO:0043583 ear development
2.21 6.39e-07 GO:0003002 regionalization
2.14 4.00e-03 GO:0045165 cell fate commitment
2.14 1.88e-02 GO:0048705 skeletal system morphogenesis
2.13 5.83e-08 GO:0016337 cell-cell adhesion
2.04 1.53e-02 GO:0048562 embryonic organ morphogenesis
2.02 6.97e-03 GO:0030900 forebrain development
1.95 2.96e-06 GO:0007389 pattern specification process
1.87 1.26e-05 GO:0048598 embryonic morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.33 4.08e-02 GO:0005604 basement membrane
2.23 1.63e-03 GO:0044420 extracellular matrix part
1.75 4.96e-04 GO:0005578 proteinaceous extracellular matrix
1.64 1.81e-03 GO:0031012 extracellular matrix
1.55 2.25e-04 GO:0030054 cell junction
1.32 3.47e-02 GO:0044421 extracellular region part
1.21 5.12e-06 GO:0005886 plasma membrane
1.20 7.01e-06 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.97 7.79e-03 GO:0008013 beta-catenin binding
2.38 1.09e-02 GO:0019199 transmembrane receptor protein kinase activity
1.77 1.67e-10 GO:0043565 sequence-specific DNA binding
1.77 3.86e-04 GO:0016563 transcription activator activity
1.64 5.99e-11 GO:0001071 nucleic acid binding transcription factor activity
1.64 5.99e-11 GO:0003700 sequence-specific DNA binding transcription factor activity
1.62 2.30e-10 GO:0030528 transcription regulator activity
1.51 5.67e-04 GO:0005509 calcium ion binding