Motif ID: HES1.p2

Z-value: 1.115


Transcription factors associated with HES1.p2:

Gene SymbolEntrez IDGene Name
HES1 3280 hairy and enhancer of split 1, (Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HES1chr3_+_1953366310.165.6e-01Click!


Activity profile for motif HES1.p2.

activity profile for motif HES1.p2


Sorted Z-values histogram for motif HES1.p2

Sorted Z-values for motif HES1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HES1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_149895274 0.985 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr7_+_116099648 0.865 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr2_-_204108151 0.812 NM_203365
NM_213589
RAPH1

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

chr20_+_36810510 0.695 NM_024855
ACTR5
ARP5 actin-related protein 5 homolog (yeast)
chr12_+_8741746 0.684 NM_020734
RIMKLB
ribosomal modification protein rimK-like family member B
chr1_-_45924770 0.636 NM_021639
GPBP1L1
GC-rich promoter binding protein 1-like 1
chr16_+_55199978 0.630 NM_005953
MT2A
metallothionein 2A
chr1_-_223907283 0.628 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr11_-_2907169 0.603 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr15_+_94674849 0.597 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr20_+_11819364 0.585 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr1_+_234372454 0.579 NM_003272
GPR137B
G protein-coupled receptor 137B
chr2_-_127580975 0.575 NM_004305
NM_139343
NM_139344
NM_139345
NM_139346
NM_139347
NM_139348
NM_139349
NM_139350
NM_139351
BIN1









bridging integrator 1









chr20_+_254205 0.565 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr8_+_120955080 0.560 NM_022783
DEPTOR
DEP domain containing MTOR-interacting protein
chr5_+_14196287 0.557 NM_007118
TRIO
triple functional domain (PTPRF interacting)
chr2_-_172458970 0.544 NM_003705
SLC25A12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr6_-_86445138 0.544 SNHG5
small nucleolar RNA host gene 5 (non-protein coding)
chr2_+_101680594 0.535 NM_004834
NM_145686
NM_145687
MAP4K4


mitogen-activated protein kinase kinase kinase kinase 4


chr15_-_53667800 0.517 PYGO1
pygopus homolog 1 (Drosophila)
chr12_+_92295738 0.505 NM_019094
NM_199040
NUDT4

NUDT4P1
nudix (nucleoside diphosphate linked moiety X)-type motif 4

nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1
chr2_+_182464910 0.503 SSFA2
sperm specific antigen 2
chr2_-_85969527 0.502 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr1_-_45444812 0.494 NM_020883
ZSWIM5
zinc finger, SWIM-type containing 5
chr2_+_203901160 0.480 NM_005759
ABI2
abl-interactor 2
chr2_+_122229590 0.475 NM_004622
TSN
translin
chr6_-_137407504 0.474 IL20RA
interleukin 20 receptor, alpha
chr17_-_77129802 0.466 NM_025161
C17orf70
chromosome 17 open reading frame 70
chr9_+_91115924 0.464 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr2_+_85619802 0.461 MAT2A
methionine adenosyltransferase II, alpha
chr16_+_30617962 0.457 NM_006662
SRCAP
Snf2-related CREBBP activator protein
chr20_-_3336219 0.455 NM_001009984
C20orf194
chromosome 20 open reading frame 194
chr8_-_142080169 0.449 NM_005607
NM_153831
PTK2

PTK2 protein tyrosine kinase 2

chr7_-_525336 0.445 PDGFA
platelet-derived growth factor alpha polypeptide
chr1_+_21639146 0.440 NM_032264
NBPF3
neuroblastoma breakpoint family, member 3
chr1_-_203557379 0.435 NM_030952
NUAK2
NUAK family, SNF1-like kinase, 2
chr1_-_9111674 0.425 NM_024980
GPR157
G protein-coupled receptor 157
chr8_+_66719441 0.424 NM_001145839
NM_014637
MTFR1

mitochondrial fission regulator 1

chr22_-_27405708 0.422 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr5_+_63497408 0.421 NM_001113561
NM_178532
RNF180

ring finger protein 180

chr3_+_37878647 0.418 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr12_+_2939250 0.417 TEAD4
TEA domain family member 4
chr12_-_105057940 0.411 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr2_-_101291483 0.411 NM_173647
RNF149
ring finger protein 149
chr6_+_157722467 0.409 NM_024630
NM_153746
ZDHHC14

zinc finger, DHHC-type containing 14

chr1_+_93317374 0.398 NM_001164391
NM_001164392
NM_001164393
NM_007358
MTF2



metal response element binding transcription factor 2



chr11_+_8660913 0.396 RPL27A
ribosomal protein L27a
chr20_-_32877029 0.395 NM_014071
NCOA6
nuclear receptor coactivator 6
chr16_-_84342129 0.392 NM_206967
C16orf74
chromosome 16 open reading frame 74
chr1_-_209818342 0.389 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr16_-_4341266 0.385 NM_016069
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr14_+_76634323 0.384 NM_033426
KIAA1737
KIAA1737
chr15_+_78858763 0.378 NM_018689
KIAA1199
KIAA1199
chr1_-_52791309 0.377 NM_001009881
NM_015269
ZCCHC11

zinc finger, CCHC domain containing 11

chr17_-_76985538 0.377


chr17_-_39757660 0.372 SLC25A39
solute carrier family 25, member 39
chr18_+_9465528 0.371 NM_006788
RALBP1
ralA binding protein 1
chr1_-_239869826 0.367 NM_014322
OPN3
opsin 3
chr9_-_83493415 0.367 NM_005077
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr2_-_218865451 0.365 NM_022152
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr17_-_17435631 0.364 NM_148172
PEMT
phosphatidylethanolamine N-methyltransferase
chr2_-_175741096 0.363 NM_001880
ATF2
activating transcription factor 2
chr2_-_179837490 0.361 NM_178123
SESTD1
SEC14 and spectrin domains 1
chr16_+_23560187 0.359 NM_001199011
NM_032486
DCTN5

dynactin 5 (p25)

chr1_-_62926533 0.355 NM_033407
DOCK7
dedicator of cytokinesis 7
chr8_-_96350575 0.355 NM_177965
C8orf37
chromosome 8 open reading frame 37
chr16_+_2593351 0.354 LOC652276
hypothetical LOC652276
chr7_+_106472243 0.353 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr20_+_30410447 0.352 ASXL1
additional sex combs like 1 (Drosophila)
chr4_-_10068055 0.351 NM_053042
ZNF518B
zinc finger protein 518B
chr6_-_163754903 0.351 LOC100526820
hypothetical LOC100526820
chr18_-_53621277 0.341 NM_005603
ATP8B1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr16_-_69880591 0.337 NM_001099642
NM_018348
FTSJD1

FtsJ methyltransferase domain containing 1

chr15_+_38013559 0.334 NM_001013703
EIF2AK4
eukaryotic translation initiation factor 2 alpha kinase 4
chr6_-_119712596 0.331 NM_005907
MAN1A1
mannosidase, alpha, class 1A, member 1
chr16_-_85974810 0.331 NM_024735
FBXO31
F-box protein 31
chr16_-_23559978 0.330 NM_024675
PALB2
partner and localizer of BRCA2
chr2_+_113119985 0.329 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr2_-_177836773 0.328 NM_001145412
NM_001145413
NFE2L2

nuclear factor (erythroid-derived 2)-like 2

chr13_+_20175481 0.325 NM_138284
IL17D
interleukin 17D
chr20_-_49818306 0.325 NM_006045
ATP9A
ATPase, class II, type 9A
chr11_+_12088639 0.324 NM_014632
MICAL2
microtubule associated monoxygenase, calponin and LIM domain containing 2
chr20_-_20641122 0.324 NM_020343
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr6_-_143307976 0.322 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr7_-_33068699 0.321 NM_001002010
NT5C3
5'-nucleotidase, cytosolic III
chr2_+_85619797 0.320 NM_005911
MAT2A
methionine adenosyltransferase II, alpha
chr17_+_42023353 0.318 NM_006178
NSF
N-ethylmaleimide-sensitive factor
chr12_-_105165805 0.318 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr3_-_88190737 0.316 NM_001008390
NM_003663
CGGBP1

CGG triplet repeat binding protein 1

chr17_+_78070853 0.309 NM_004514
FOXK2
forkhead box K2
chr17_-_33043514 0.305 NM_001163544
NM_001163545
NM_001163546
NM_001163547
NM_007247
NM_080550
NM_198882
SYNRG






synergin, gamma






chr11_+_76171780 0.304 NM_015516
TSKU
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr20_+_6696744 0.303 NM_001200
BMP2
bone morphogenetic protein 2
chr16_+_66484671 0.300 NM_006742
PSKH1
protein serine kinase H1
chr6_-_138470160 0.299 NM_022121
PERP
PERP, TP53 apoptosis effector
chr19_+_4353658 0.298 NM_005483
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr2_-_54051290 0.298 NM_014614
PSME4
proteasome (prosome, macropain) activator subunit 4
chr1_+_26310854 0.298 NM_152835
PDIK1L
PDLIM1 interacting kinase 1 like
chr9_+_130354490 0.298 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr1_+_25629968 0.294 NM_018202
TMEM57
transmembrane protein 57
chr5_+_90711887 0.294 LOC100129716
hypothetical LOC100129716
chr2_-_200424140 0.293 LOC348751
hypothetical LOC348751
chr11_-_93114155 0.292 NM_024116
TAF1D
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
chr11_+_63883192 0.292 NM_001006944
NM_003942
RPS6KA4

ribosomal protein S6 kinase, 90kDa, polypeptide 4

chrX_-_9693916 0.292 NM_000273
GPR143
G protein-coupled receptor 143
chr7_-_139987044 0.291 DENND2A
DENN/MADD domain containing 2A
chr10_+_73393998 0.291 NM_004273
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr20_-_49818268 0.289 ATP9A
ATPase, class II, type 9A
chr9_-_21549696 0.287 LOC554202
hypothetical LOC554202
chr2_+_177785667 0.284 NM_194247
HNRNPA3P1
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
heterogeneous nuclear ribonucleoprotein A3
chr12_-_46499834 0.283 NM_001098416
NM_015401
HDAC7

histone deacetylase 7

chr6_-_44333002 0.282 NM_178148
SLC35B2
solute carrier family 35, member B2
chr14_-_24588916 0.282 NM_014178
STXBP6
syntaxin binding protein 6 (amisyn)
chr17_-_27210330 0.282 NM_018405
C17orf79
chromosome 17 open reading frame 79
chr4_+_39734902 0.279 NM_018177
N4BP2
NEDD4 binding protein 2
chr20_-_42373151 0.279 NM_001080472
FITM2
fat storage-inducing transmembrane protein 2
chr7_+_93977267 0.276 CASD1
CAS1 domain containing 1
chr8_+_41554823 0.275 NM_178819
AGPAT6
1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)
chr1_-_16812274 0.273 NM_017940
NBPF1
neuroblastoma breakpoint family, member 1
chr2_-_175255717 0.272 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr2_+_170363573 0.271 NM_003142
SSB
Sjogren syndrome antigen B (autoantigen La)
chr13_-_105985313 0.270 NM_004093
EFNB2
ephrin-B2
chr1_-_150232900 0.270 S100A10
S100 calcium binding protein A10
chr2_+_11804190 0.269 NM_145693
LPIN1
lipin 1
chrX_-_41667174 0.267 NM_001126054
NM_001126055
NM_003688
CASK


calcium/calmodulin-dependent serine protein kinase (MAGUK family)


chr2_-_99472910 0.267 NM_001037872
NM_016316
REV1

REV1 homolog (S. cerevisiae)

chr3_-_127558747 0.264 NM_014079
KLF15
Kruppel-like factor 15
chr6_-_150431864 0.262 NM_024518
ULBP3
UL16 binding protein 3
chr13_+_26723689 0.262 NM_000982
RPL21
ribosomal protein L21
chr1_-_92124064 0.260 TGFBR3
transforming growth factor, beta receptor III
chr19_-_1603325 0.258 NM_003200
TCF3
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
chr11_+_35922106 0.257 NM_174902
LDLRAD3
low density lipoprotein receptor class A domain containing 3
chr8_+_59069522 0.256 NM_147189
FAM110B
family with sequence similarity 110, member B
chr6_-_160599779 0.255 NM_003058
SLC22A2
solute carrier family 22 (organic cation transporter), member 2
chr3_-_187025501 0.255 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr16_+_56038837 0.253 NM_020312
COQ9
coenzyme Q9 homolog (S. cerevisiae)
chr16_+_8799170 0.252 NM_000303
PMM2
phosphomannomutase 2
chr6_+_131498540 0.251 AKAP7
A kinase (PRKA) anchor protein 7
chr11_+_10283171 0.250 NM_001124
ADM
adrenomedullin
chr7_+_24579239 0.250 NM_016447
MPP6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr17_-_73867748 0.245 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr16_-_21439195 0.244 SLC7A5P2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 pseudogene 2
chr9_-_129370954 0.244 FAM129B
family with sequence similarity 129, member B
chr12_-_41269679 0.244 NM_153026
PRICKLE1
prickle homolog 1 (Drosophila)
chr10_-_104463947 0.243 NM_004311
ARL3
ADP-ribosylation factor-like 3
chr7_-_97719372 0.243 NM_015395
TECPR1
tectonin beta-propeller repeat containing 1
chr11_-_63770716 0.243 PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr4_-_141896920 0.242 NM_015130
TBC1D9
TBC1 domain family, member 9 (with GRAM domain)
chr15_-_53668341 0.242 NM_015617
PYGO1
pygopus homolog 1 (Drosophila)
chr6_-_84994032 0.242 NM_014895
KIAA1009
KIAA1009
chr7_-_86686754 0.241 NM_024315
C7orf23
chromosome 7 open reading frame 23
chr11_-_17055763 0.241 NM_001017
RPS13
ribosomal protein S13
chr1_+_165456572 0.241 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr17_+_69939806 0.239 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr1_+_52380633 0.239 NM_004799
NM_007323
NM_007324
ZFYVE9


zinc finger, FYVE domain containing 9


chr2_+_36436873 0.236 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr3_-_187025438 0.235 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr2_-_38457934 0.235 NM_001135673
NM_022374
ATL2

atlastin GTPase 2

chr1_+_25999245 0.233 NM_020451
NM_206926
SEPN1

selenoprotein N, 1

chr9_-_135847106 0.232 NM_001134398
NM_003371
VAV2

vav 2 guanine nucleotide exchange factor

chr16_-_56038771 0.231 NM_020313
CIAPIN1
cytokine induced apoptosis inhibitor 1
chr19_-_15351523 0.231 NM_005858
AKAP8
A kinase (PRKA) anchor protein 8
chr16_-_11852862 0.230 NM_015659
RSL1D1
ribosomal L1 domain containing 1
chr11_-_10272256 0.230 NM_030962
SBF2
SET binding factor 2
chr15_-_78003059 0.229 NM_001100880
ST20
suppressor of tumorigenicity 20
chr19_-_17217022 0.229 NM_005234
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr6_-_112682038 0.229 LAMA4
laminin, alpha 4
chr17_+_52517529 0.229 NM_003488
AKAP1
A kinase (PRKA) anchor protein 1
chr2_-_39201066 0.228 NM_005633
SOS1
son of sevenless homolog 1 (Drosophila)
chr3_+_142143329 0.228 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr4_-_140696740 0.227 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr17_-_1306160 0.226 NM_005206
NM_016823
CRK

v-crk sarcoma virus CT10 oncogene homolog (avian)

chr19_-_1814546 0.226 NM_031918
KLF16
Kruppel-like factor 16
chr11_-_101828563 0.225 NM_052932
TMEM123
transmembrane protein 123
chr2_-_177837540 0.225 NFE2L2
nuclear factor (erythroid-derived 2)-like 2
chr3_-_17759100 0.224 NM_001134380
TBC1D5
TBC1 domain family, member 5
chr13_-_78131259 0.224 NM_024546
RNF219
ring finger protein 219
chr15_+_83092854 0.223 ZNF592
zinc finger protein 592
chr2_-_20413838 0.223 PUM2
pumilio homolog 2 (Drosophila)
chr12_+_26003218 0.223 NM_001164748
NM_007211
RASSF8

Ras association (RalGDS/AF-6) domain family (N-terminal) member 8

chr2_+_182464713 0.222 NM_001130445
NM_006751
SSFA2

sperm specific antigen 2

chr2_-_197499584 0.221 NM_024989
PGAP1
post-GPI attachment to proteins 1
chr1_+_153846602 0.221 NM_018116
MSTO1
misato homolog 1 (Drosophila)
chr2_+_10360471 0.221 NM_002149
HPCAL1
hippocalcin-like 1
chr1_-_154290112 0.220 NM_020131
UBQLN4
ubiquilin 4
chr6_+_10855977 0.219 NM_001127711
NM_030969
TMEM14B

transmembrane protein 14B

chr9_+_137511448 0.219 NM_014811
KIAA0649
KIAA0649
chr12_+_66328760 0.218 NM_003583
NM_006482
DYRK2

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2

chr6_+_111911226 0.218 LOC643749
hypothetical LOC643749
chr17_-_19206475 0.217 NM_015681
B9D1
B9 protein domain 1
chr2_+_187059277 0.217 ZC3H15
zinc finger CCCH-type containing 15
chr20_-_61317891 0.215 NM_017798
YTHDF1
YTH domain family, member 1
chr1_+_164063684 0.215 UCK2
uridine-cytidine kinase 2
chr2_+_242289983 0.215 NM_032329
ING5
inhibitor of growth family, member 5
chr6_+_24234328 0.214 NM_080723
NRSN1
neurensin 1
chr4_+_25930405 0.214 NM_005349
NM_203283
RBPJ

recombination signal binding protein for immunoglobulin kappa J region

chr20_-_48980858 0.214 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr9_-_129371171 0.212 NM_022833
FAM129B
family with sequence similarity 129, member B
chr16_+_24459173 0.212 RBBP6
retinoblastoma binding protein 6
chr17_-_45562112 0.212 NM_174920
SAMD14
sterile alpha motif domain containing 14

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.30 2.58e-31 GO:0044237 cellular metabolic process
1.36 4.73e-26 GO:0044260 cellular macromolecule metabolic process
1.26 5.99e-24 GO:0044238 primary metabolic process
1.24 3.60e-23 GO:0008152 metabolic process
1.29 5.30e-19 GO:0043170 macromolecule metabolic process
1.12 3.65e-16 GO:0009987 cellular process
1.40 4.29e-15 GO:0044267 cellular protein metabolic process
1.37 1.95e-14 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34 2.37e-14 GO:0034641 cellular nitrogen compound metabolic process
1.39 6.89e-14 GO:0009058 biosynthetic process
1.33 1.15e-13 GO:0006807 nitrogen compound metabolic process
1.39 2.09e-13 GO:0044249 cellular biosynthetic process
1.43 8.24e-12 GO:0006464 protein modification process
1.39 3.14e-10 GO:0043412 macromolecule modification
1.30 5.72e-10 GO:0019538 protein metabolic process
1.25 2.23e-08 GO:0071840 cellular component organization or biogenesis
1.33 3.25e-08 GO:0090304 nucleic acid metabolic process
1.25 5.80e-08 GO:0016043 cellular component organization
1.29 6.22e-08 GO:0071841 cellular component organization or biogenesis at cellular level
1.28 3.73e-07 GO:0071842 cellular component organization at cellular level
1.34 6.62e-07 GO:0010467 gene expression
1.36 1.07e-06 GO:0009059 macromolecule biosynthetic process
1.35 1.58e-06 GO:0016070 RNA metabolic process
1.35 2.06e-06 GO:0034645 cellular macromolecule biosynthetic process
1.46 2.99e-06 GO:0006793 phosphorus metabolic process
1.46 2.99e-06 GO:0006796 phosphate metabolic process
1.34 8.76e-06 GO:0006996 organelle organization
1.35 7.84e-05 GO:0009966 regulation of signal transduction
1.49 1.45e-04 GO:0006468 protein phosphorylation
1.44 4.34e-04 GO:0016310 phosphorylation
1.49 7.58e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.38 1.16e-03 GO:0007049 cell cycle
1.38 1.29e-03 GO:0032268 regulation of cellular protein metabolic process
1.11 1.77e-03 GO:0050794 regulation of cellular process
1.28 4.83e-03 GO:0023051 regulation of signaling
1.60 6.16e-03 GO:0016568 chromatin modification
1.43 6.66e-03 GO:0019220 regulation of phosphate metabolic process
1.43 6.66e-03 GO:0051174 regulation of phosphorus metabolic process
1.10 7.33e-03 GO:0050789 regulation of biological process
1.34 7.43e-03 GO:0051246 regulation of protein metabolic process
1.68 1.01e-02 GO:0010608 posttranscriptional regulation of gene expression
1.45 1.07e-02 GO:0051276 chromosome organization
1.38 1.21e-02 GO:0033554 cellular response to stress
1.54 1.24e-02 GO:0072521 purine-containing compound metabolic process
1.25 1.54e-02 GO:0044281 small molecule metabolic process
1.42 2.09e-02 GO:0042325 regulation of phosphorylation
1.65 2.33e-02 GO:0032446 protein modification by small protein conjugation
1.20 2.45e-02 GO:0048522 positive regulation of cellular process
1.43 2.58e-02 GO:0001932 regulation of protein phosphorylation
1.38 2.58e-02 GO:0031399 regulation of protein modification process
1.09 2.81e-02 GO:0065007 biological regulation
2.30 2.92e-02 GO:0007173 epidermal growth factor receptor signaling pathway
1.33 3.05e-02 GO:0032774 RNA biosynthetic process
1.45 3.11e-02 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.58 3.64e-02 GO:0070647 protein modification by small protein conjugation or removal
1.51 4.16e-02 GO:0040008 regulation of growth
1.40 4.81e-02 GO:0046483 heterocycle metabolic process
1.65 4.89e-02 GO:0016567 protein ubiquitination

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 1.21e-44 GO:0005622 intracellular
1.18 1.39e-43 GO:0044424 intracellular part
1.22 3.44e-29 GO:0005737 cytoplasm
1.18 6.21e-27 GO:0043226 organelle
1.18 1.21e-26 GO:0043229 intracellular organelle
1.19 4.64e-24 GO:0043227 membrane-bounded organelle
1.19 5.81e-24 GO:0043231 intracellular membrane-bounded organelle
1.24 1.29e-17 GO:0005634 nucleus
1.23 1.65e-17 GO:0044444 cytoplasmic part
1.39 6.23e-14 GO:0043233 organelle lumen
1.22 6.40e-14 GO:0044446 intracellular organelle part
1.39 9.54e-14 GO:0070013 intracellular organelle lumen
1.41 1.83e-13 GO:0005829 cytosol
1.38 2.30e-13 GO:0031974 membrane-enclosed lumen
1.44 2.36e-13 GO:0031981 nuclear lumen
1.39 2.88e-13 GO:0044428 nuclear part
1.21 2.89e-13 GO:0044422 organelle part
1.28 1.70e-08 GO:0043228 non-membrane-bounded organelle
1.28 1.70e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.70 4.05e-08 GO:0005730 nucleolus
1.41 4.58e-08 GO:0005654 nucleoplasm
1.05 5.46e-08 GO:0044464 cell part
1.05 5.81e-08 GO:0005623 cell
1.33 5.94e-05 GO:0005739 mitochondrion
1.18 1.26e-04 GO:0032991 macromolecular complex
1.17 1.27e-02 GO:0043234 protein complex
1.43 1.43e-02 GO:0030529 ribonucleoprotein complex
1.34 3.24e-02 GO:0044451 nucleoplasm part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 9.86e-23 GO:0005515 protein binding
1.11 1.67e-16 GO:0005488 binding
1.21 2.23e-12 GO:0003824 catalytic activity
1.33 2.05e-09 GO:0000166 nucleotide binding
1.37 1.36e-08 GO:0016740 transferase activity
1.32 6.76e-07 GO:0017076 purine nucleotide binding
1.32 7.05e-07 GO:0032553 ribonucleotide binding
1.32 7.05e-07 GO:0032555 purine ribonucleotide binding
1.36 8.18e-07 GO:0030554 adenyl nucleotide binding
1.35 9.94e-07 GO:0032559 adenyl ribonucleotide binding
1.51 2.55e-06 GO:0019899 enzyme binding
1.31 2.75e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.35 3.17e-06 GO:0005524 ATP binding
1.44 9.01e-06 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.60 5.12e-05 GO:0016874 ligase activity
1.73 1.37e-04 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.76 2.02e-04 GO:0016881 acid-amino acid ligase activity
1.95 5.30e-04 GO:0000287 magnesium ion binding
1.75 1.72e-03 GO:0019787 small conjugating protein ligase activity
1.53 2.94e-03 GO:0004674 protein serine/threonine kinase activity
5.33 4.57e-03 GO:0008139 nuclear localization sequence binding
1.17 4.70e-03 GO:0003676 nucleic acid binding
1.36 5.12e-03 GO:0003723 RNA binding
1.42 6.94e-03 GO:0004672 protein kinase activity
1.38 7.35e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.71 8.14e-03 GO:0004842 ubiquitin-protein ligase activity
1.34 2.70e-02 GO:0016301 kinase activity
1.56 2.71e-02 GO:0016564 transcription repressor activity