Motif ID: HLF.p2

Z-value: 2.039


Transcription factors associated with HLF.p2:

Gene SymbolEntrez IDGene Name
HLF 3131 hepatic leukemia factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HLFchr17_+_50697355-0.322.2e-01Click!


Activity profile for motif HLF.p2.

activity profile for motif HLF.p2


Sorted Z-values histogram for motif HLF.p2

Sorted Z-values for motif HLF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HLF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_113601608 4.060 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr11_+_111552298 3.905 NM_001037290
BCO2
beta-carotene oxygenase 2
chr2_-_113310796 3.815 NM_000576
IL1B
interleukin 1, beta
chr1_-_177106702 3.108 NM_004673
ANGPTL1
angiopoietin-like 1
chr2_+_64540843 3.076 HSPC159
galectin-related protein
chr4_-_77147625 2.864 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr2_+_113601616 2.829 IL1RN
interleukin 1 receptor antagonist
chr11_-_102081654 2.582 NM_022122
MMP27
matrix metallopeptidase 27
chr6_-_30151526 2.136 NM_170769
NM_025236
RNF39

ring finger protein 39

chr9_+_116131889 2.134 NM_000608
ORM2
orosomucoid 2
chr1_-_205210567 2.085 NM_001122979
NM_001170631
NM_032029
FCAMR


Fc receptor, IgA, IgM, high affinity


chr12_-_51132129 2.080 NM_005555
KRT6B
keratin 6B
chr9_+_116125123 2.013 NM_000607
ORM1
orosomucoid 1
chr7_+_128136347 1.969 FAM71F1
family with sequence similarity 71, member F1
chr10_-_14412813 1.933 NM_018027
FRMD4A
FERM domain containing 4A
chr3_-_152585226 1.883 NM_022788
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr11_-_10487212 1.808 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr10_+_18669619 1.771 NM_201590
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr6_-_169395972 1.765 NM_003247
THBS2
thrombospondin 2
chr5_-_39400319 1.754 NM_001737
C9
complement component 9
chr12_-_103846186 1.738 NM_032148
SLC41A2
solute carrier family 41, member 2
chr12_-_86947276 1.682 NM_152589
C12orf50
chromosome 12 open reading frame 50
chr19_-_40684638 1.664 NM_001035516
DMKN
dermokine
chr6_-_169395847 1.511 THBS2
thrombospondin 2
chr2_-_98646367 1.459 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr3_+_46591048 1.455 NM_001174136
TDGF1
teratocarcinoma-derived growth factor 1
chr14_+_20493467 1.449 NM_002934
RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr20_+_54533191 1.449 NM_001012971
C20orf106
C20orf107
chromosome 20 open reading frame 106
chromosome 20 open reading frame 107
chr3_+_187866464 1.392 NM_000412
HRG
histidine-rich glycoprotein
chr2_+_219453487 1.377 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr4_-_87989291 1.377 NM_197965
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr12_-_121767272 1.365 NM_006018
GPR109B
G protein-coupled receptor 109B
chr11_-_4675524 1.362 NM_030774
OR51E2
olfactory receptor, family 51, subfamily E, member 2
chr5_+_36642213 1.284 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr3_+_187917791 1.272 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr17_-_36528113 1.267 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr3_-_58175437 1.260 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr12_+_123339662 1.259 NM_181709
FAM101A
family with sequence similarity 101, member A
chr1_+_239762179 1.258 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr10_+_85994788 1.251 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr12_-_4624536 1.247 NM_006422
AKAP3
A kinase (PRKA) anchor protein 3
chr19_+_40541327 1.235 NM_005304
FFAR3
free fatty acid receptor 3
chr14_+_95792299 1.218 NM_000710
BDKRB1
bradykinin receptor B1
chr6_-_30188845 1.198 NM_007028
TRIM31
tripartite motif containing 31
chr11_-_76862197 1.180 NM_001128620
NM_002576
PAK1

p21 protein (Cdc42/Rac)-activated kinase 1

chr4_+_1864306 1.160 NM_007331
NM_133330
NM_133331
NM_133335
WHSC1



Wolf-Hirschhorn syndrome candidate 1



chr1_-_21373816 1.143 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr7_-_111216180 1.110 DOCK4
dedicator of cytokinesis 4
chr20_+_58064360 1.108 NM_173644
C20orf197
chromosome 20 open reading frame 197
chr15_+_56217686 1.107 NM_020980
AQP9
aquaporin 9
chr12_-_121753795 1.104 NM_177551
GPR109A
G protein-coupled receptor 109A
chr22_+_17539198 1.096


chr3_+_171167243 1.088 NM_003262
SEC62
SEC62 homolog (S. cerevisiae)
chr2_+_65517316 1.059 FLJ16124
FLJ16124 protein
chr20_-_43177137 1.050 NM_145652
WFDC5
WAP four-disulfide core domain 5
chr16_+_70654625 1.043 NM_020995
HPR
haptoglobin-related protein
chr1_+_152644471 1.034 IL6R
interleukin 6 receptor
chr2_+_113542017 1.033 NM_173161
IL1F10
interleukin 1 family, member 10 (theta)
chr20_-_1548589 1.032 NM_001083910
NM_001135844
NM_006065
SIRPB1


signal-regulatory protein beta 1


chr2_+_178893216 1.014 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr17_+_3326045 0.984 NM_000049
ASPA
aspartoacylase
chr17_+_31455332 0.955 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr12_-_13147839 0.947 NM_001080554
NM_001080555
GSG1

germ cell associated 1

chr16_+_70646008 0.923 NM_001126102
NM_005143
HP

haptoglobin

chr6_-_50045296 0.919 NM_001037729
DEFB113
defensin, beta 113
chr1_-_171441234 0.904 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr8_-_6722848 0.889 NM_005218
DEFB1
defensin, beta 1
chr6_+_17501589 0.881 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr12_-_119451303 0.881 NM_032314
COQ5
coenzyme Q5 homolog, methyltransferase (S. cerevisiae)
chr11_+_113280727 0.875 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr21_+_44597911 0.862 NM_003307
TRPM2
transient receptor potential cation channel, subfamily M, member 2
chr4_-_104338924 0.857 NM_001813
CENPE
centromere protein E, 312kDa
chr7_-_44992729 0.842 C7orf40
chromosome 7 open reading frame 40
chr2_+_101974737 0.828 NM_004633
IL1R2
interleukin 1 receptor, type II
chr3_-_171070314 0.816 NM_024727
LRRC31
leucine rich repeat containing 31
chr5_+_156628929 0.777 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr5_+_73145098 0.770 RGNEF
190 kDa guanine nucleotide exchange factor
chr1_+_205328834 0.767 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr12_-_28016182 0.766 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr20_-_55718982 0.757 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr14_-_22354389 0.745 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr1_+_205137410 0.739 NM_001185156
NM_001185157
NM_001185158
NM_006850
IL24



interleukin 24



chr19_-_45611110 0.734 NM_020956
NM_181882
PRX

periaxin

chr6_-_139654807 0.732 NM_153235
TXLNB
taxilin beta
chr8_+_26569709 0.730 DPYSL2
dihydropyrimidinase-like 2
chr8_-_10550026 0.720 NM_178857
RP1L1
retinitis pigmentosa 1-like 1
chr6_+_88021644 0.713 ZNF292
zinc finger protein 292
chr7_-_143597313 0.705 NM_198495
CTAGE4
CTAGE8
CTAGE family, member 4
CTAGE family, member 8
chr1_-_228916486 0.699 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_-_67039518 0.690 NM_005478
INSL5
insulin-like 5
chr9_-_34719463 0.689 NM_001141917
C9orf144B
transmembrane protein C9orf144B
chr5_-_79982584 0.688 NM_001190470
MTRNR2L2
MT-RNR2-like 2
chr6_+_150731720 0.684 NM_001164694
NM_001164695
NM_203395
IYD


iodotyrosine deiodinase


chr7_-_141048358 0.683 NM_001080392
KIAA1147
KIAA1147
chr9_+_140226457 0.682 NM_001145249
FAM157B
family with sequence similarity 157, member B
chr2_+_232165818 0.682 NM_152614
C2orf57
chromosome 2 open reading frame 57
chr20_+_16676997 0.679 NM_020157
OTOR
otoraplin
chr12_+_46878406 0.676 DKFZP779L1853
hypothetical LOC643162
chr17_-_53976681 0.659 NM_001038704
C17orf47
chromosome 17 open reading frame 47
chr19_+_53801811 0.655 NM_133498
SPACA4
sperm acrosome associated 4
chr11_+_111551417 0.655 NM_031938
BCO2
beta-carotene oxygenase 2
chr5_+_96023479 0.645 NM_001190442
CAST
calpastatin
chr5_+_36642424 0.638 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_-_36346240 0.638 KRT23
keratin 23 (histone deacetylase inducible)
chr19_-_56147971 0.628 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr4_-_78216145 0.624 NM_006835
CCNI
cyclin I
chr17_+_36493927 0.619 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr7_-_143560850 0.618 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr6_+_144654565 0.617 NM_007124
UTRN
utrophin
chr1_+_171871283 0.616 NM_001195190
LOC730159
hypothetical protein LOC730159
chr1_+_157167965 0.610 NM_152501
NM_198928
NM_198929
NM_198930
PYHIN1



pyrin and HIN domain family, member 1



chr5_+_6799100 0.609 NM_001171806
PAPD7
PAP associated domain containing 7
chr3_-_45858566 0.602 NM_020347
LZTFL1
leucine zipper transcription factor-like 1
chr1_-_228916559 0.593 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_-_151614681 0.592 NM_005621
S100A12
S100 calcium binding protein A12
chr5_+_14493905 0.583 TRIO
triple functional domain (PTPRF interacting)
chr6_-_52217185 0.582 NM_052872
IL17F
interleukin 17F
chr7_+_143511480 0.582 NM_198495
CTAGE4
CTAGE8
CTAGE family, member 4
CTAGE family, member 8
chr1_-_228916470 0.577 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr4_+_77214886 0.570 NM_001130016
NM_001179
ART3

ADP-ribosyltransferase 3

chr16_+_9093035 0.570 NM_014117
C16orf72
chromosome 16 open reading frame 72
chr8_+_128497038 0.568 NM_001159542
POU5F1B
POU class 5 homeobox 1B
chr17_+_36515166 0.565 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr17_-_31353196 0.563 NM_032965
CCL15
chemokine (C-C motif) ligand 15
chr3_+_143824955 0.560 NM_002670
PLS1
plastin 1
chr6_-_32447626 0.559 NM_006781
C6orf10
chromosome 6 open reading frame 10
chr16_+_4546491 0.557 NM_001145011
LOC342346
hypothetical protein LOC342346
chr12_-_47031287 0.553 NM_001172682
ZNF641
zinc finger protein 641
chr7_+_142723340 0.550 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr5_-_178977441 0.549 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr1_-_1580266 0.549 CDK11A
CDK11B
cyclin-dependent kinase 11A
cyclin-dependent kinase 11B
chr21_-_29286982 0.545 NM_015565
LTN1
listerin E3 ubiquitin protein ligase 1
chr6_+_33284241 0.545 NM_002931
RING1
ring finger protein 1
chr14_-_22354457 0.544 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr20_+_29492071 0.537 NM_153324
DEFB123
defensin, beta 123
chr5_+_96023926 0.535 CAST
calpastatin
chr1_+_207944807 0.535 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr1_+_227506751 0.533 NM_006542
SPHAR
S-phase response (cyclin related)
chr19_+_40716153 0.532 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr1_+_239882202 0.529 NM_144625
WDR64
WD repeat domain 64
chr6_+_32048077 0.527 STK19
serine/threonine kinase 19
chr7_+_115650240 0.526 NM_152829
TES
testis derived transcript (3 LIM domains)
chr19_-_6410735 0.521 NM_024103
SLC25A23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr17_-_36559579 0.520 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr11_-_18226743 0.518 NM_001127380
NM_030754
SAA2

serum amyloid A2

chr1_-_201162938 0.517 KLHL12
kelch-like 12 (Drosophila)
chr9_+_674193 0.515


chr16_+_31036474 0.511 NM_032188
NM_182958
MYST1

MYST histone acetyltransferase 1

chr17_+_37122138 0.510 NM_000805
GAST
gastrin
chr17_-_31352643 0.504 CCL14-CCL15
CCL15
CCL14-CCL15 read-through transcript
chemokine (C-C motif) ligand 15
chr7_+_149778815 0.502 GIMAP8
GTPase, IMAP family member 8
chr19_-_59568483 0.501 NM_002287
NM_021706
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr7_-_143085704 0.499 NM_178561
CTAGE6P
CTAGE family, member 6, pseudogene
chr8_+_124263932 0.499 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr4_-_171161486 0.497 NM_001009554
MFAP3L
microfibrillar-associated protein 3-like
chr9_-_111230926 0.493 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr12_-_51360439 0.492 NM_006121
KRT1
keratin 1
chr3_-_12561962 0.485 NM_001195279
LOC100129480
hypothetical protein LOC100129480
chr14_+_19458580 0.480 NM_001005483
OR4K5
olfactory receptor, family 4, subfamily K, member 5
chr1_-_240228987 0.480 NM_001004343
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr1_-_9040141 0.479 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr6_-_133076873 0.479 NM_004666
VNN1
vanin 1
chr8_+_22075112 0.477 NM_001172357
NM_001172410
NM_003018
SFTPC


surfactant protein C


chr1_+_210805319 0.465 NM_001030287
ATF3
activating transcription factor 3
chr3_-_145049853 0.461 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr2_-_128155829 0.457 NM_001161404
LIMS2
LIM and senescent cell antigen-like domains 2
chr5_-_138746840 0.457 SLC23A1
solute carrier family 23 (nucleobase transporters), member 1
chr9_-_122679387 0.455 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr1_+_84636802 0.454 NM_021233
DNASE2B
deoxyribonuclease II beta
chr10_+_70650064 0.453 NM_025130
HKDC1
hexokinase domain containing 1
chr17_-_61655915 0.452 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr1_-_201162991 0.452 NM_021633
KLHL12
kelch-like 12 (Drosophila)
chr5_+_149131695 0.451 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr9_-_90456824 0.450 NM_001100111
LOC286238
hypothetical protein LOC286238
chr3_-_159872960 0.446 NM_020169
LXN
latexin
chr1_+_152644668 0.443 IL6R
interleukin 6 receptor
chr14_+_59785703 0.437 NM_021003
NM_177951
PPM1A

protein phosphatase, Mg2+/Mn2+ dependent, 1A

chr8_-_97316933 0.436 NM_006294
UQCRB
ubiquinol-cytochrome c reductase binding protein
chr1_+_1104939 0.433 NM_153254
TTLL10
tubulin tyrosine ligase-like family, member 10
chr11_-_6418705 0.425 NM_000613
HPX
hemopexin
chr20_-_48980858 0.422 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr1_-_152867007 0.420 ADAR
adenosine deaminase, RNA-specific
chr2_+_46623396 0.419 RHOQ
ras homolog gene family, member Q
chr3_-_49701085 0.417 NM_020998
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr14_+_59785723 0.415 PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr10_-_82039158 0.414 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr5_+_96023627 0.413 NM_001042440
CAST
calpastatin
chr6_-_24597717 0.411 NM_177483
NM_001503
GPLD1

glycosylphosphatidylinositol specific phospholipase D1

chr6_+_42231121 0.411 NM_000409
GUCA1A
guanylate cyclase activator 1A (retina)
chr2_+_3683660 0.409 NM_018436
ALLC
allantoicase
chr7_+_142978994 0.400 NM_001008747
CTAGE6P
CTAGE15P
CTAGE family, member 6, pseudogene
CTAGE family, member 15, pseudogene
chr3_+_99671013 0.399 NM_001004736
OR5K1
olfactory receptor, family 5, subfamily K, member 1
chr1_+_152644292 0.395 NM_000565
NM_181359
IL6R

interleukin 6 receptor

chr3_-_101077605 0.392 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr16_+_29942155 0.390 NM_001109659
NM_001109660
C16orf92

chromosome 16 open reading frame 92

chr1_+_151117421 0.389 NM_030663
SMCP
sperm mitochondria-associated cysteine-rich protein
chr15_+_60838053 0.388 TLN2
talin 2
chr7_+_134114701 0.388 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr8_+_110621485 0.385 NM_004215
EBAG9
estrogen receptor binding site associated, antigen, 9
chr9_+_70046658 0.384 NM_201453
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.