Motif ID: HOXA9_MEIS1.p2

Z-value: 0.575


Transcription factors associated with HOXA9_MEIS1.p2:

Gene SymbolEntrez IDGene Name
HOXA9 3205 homeobox A9
MEIS1 4211 Meis homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MEIS1chr2_+_66516020-0.292.8e-01Click!
HOXA9chr7_-_271716000.185.0e-01Click!


Activity profile for motif HOXA9_MEIS1.p2.

activity profile for motif HOXA9_MEIS1.p2


Sorted Z-values histogram for motif HOXA9_MEIS1.p2

Sorted Z-values for motif HOXA9_MEIS1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXA9_MEIS1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_122357104 0.671 NM_001128843
TNIP3
TNFAIP3 interacting protein 3
chr13_+_77007809 0.612 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr1_-_115039614 0.540 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr4_+_47403107 0.533


chr22_+_23921072 0.530 KIAA1671
KIAA1671
chr3_-_191650291 0.507 NM_207316
TMEM207
transmembrane protein 207
chr18_+_18989786 0.487 NM_138375
CABLES1
Cdk5 and Abl enzyme substrate 1
chr19_+_61624 0.395 NM_001005240
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr9_-_99740243 0.391 NM_197978
HEMGN
hemogen
chr1_-_611896 0.363 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr16_-_52877868 0.301 NM_024336
IRX3
iroquois homeobox 3
chr2_-_37269193 0.292 NM_001032377
SULT6B1
sulfotransferase family, cytosolic, 6B, member 1
chr8_-_17599438 0.286 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr3_-_121445831 0.283 NM_001168271
NM_153002
GPR156

G protein-coupled receptor 156

chr9_+_6205804 0.281 IL33
interleukin 33
chr11_-_4675524 0.279 NM_030774
OR51E2
olfactory receptor, family 51, subfamily E, member 2
chr19_-_15451203 0.269 NM_052890
PGLYRP2
peptidoglycan recognition protein 2
chr7_+_143457083 0.269 NM_001001659
OR2A14
olfactory receptor, family 2, subfamily A, member 14
chr8_-_27997306 0.264 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr1_+_357502 0.263 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr11_+_27019084 0.261 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_+_24522116 0.250 NM_021180
GRHL3
grainyhead-like 3 (Drosophila)
chr15_-_100280784 0.242 NM_001004195
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr11_-_8921155 0.235 NM_020646
ASCL3
achaete-scute complex homolog 3 (Drosophila)
chr5_+_140730014 0.232 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr3_-_188903038 0.230 NM_001004312
RTP2
receptor (chemosensory) transporter protein 2
chr2_+_237143118 0.228 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr15_+_36776090 0.226 NM_207444
C15orf53
chromosome 15 open reading frame 53
chr15_-_41346346 0.225 NM_004245
NM_201631
TGM5

transglutaminase 5

chr12_-_10453409 0.210 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chr1_+_115373937 0.208 NM_000549
TSHB
thyroid stimulating hormone, beta
chr9_-_72926333 0.205 NM_001007471
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr10_+_115988999 0.199 NM_198496
VWA2
von Willebrand factor A domain containing 2
chr21_-_46849413 0.195 NM_006272
S100B
S100 calcium binding protein B
chr3_+_99699137 0.195 NM_001004737
OR5K2
olfactory receptor, family 5, subfamily K, member 2
chr1_+_58899 0.195 NM_001005484
OR4F4
OR4F5
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 5
chr1_-_93172119 0.194


chr1_+_67404756 0.190 NM_144701
IL23R
interleukin 23 receptor
chr11_-_62145952 0.183 NM_012200
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr1_-_153477511 0.182 GBA
glucosidase, beta, acid
chr12_-_119249938 0.178 NM_000928
PLA2G1B
phospholipase A2, group IB (pancreas)
chr11_+_55297489 0.174 NM_001001967
OR5D13
olfactory receptor, family 5, subfamily D, member 13
chr6_-_52217185 0.173 NM_052872
IL17F
interleukin 17F
chr14_+_19285426 0.169 NM_172194
OR4Q3
olfactory receptor, family 4, subfamily Q, member 3
chr4_+_123311207 0.165 NM_015312
KIAA1109
KIAA1109
chr15_-_74091817 0.161 NM_138573
NRG4
neuregulin 4
chr2_-_21081694 0.158 APOB
apolipoprotein B (including Ag(x) antigen)
chr5_+_140780720 0.157 NM_018914
NM_032091
NM_032092
PCDHGA11


protocadherin gamma subfamily A, 11


chr12_-_49708279 0.153 NM_001174125
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr6_-_138581319 0.153 NM_021635
PBOV1
prostate and breast cancer overexpressed 1
chrX_+_37750778 0.152 NM_001163335
NM_138780
SYTL5

synaptotagmin-like 5

chr3_+_35697432 0.150 NM_198399
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr1_-_154041393 0.148 GON4L
gon-4-like (C. elegans)
chr8_-_6407882 0.145 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr4_-_120445047 0.144 NM_001170330
C4orf3
chromosome 4 open reading frame 3
chr3_-_173723754 0.143 NM_001190943
NM_001190942
NM_003810
TNFSF10


tumor necrosis factor (ligand) superfamily, member 10


chr7_+_143646150 0.139 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr22_+_21393107 0.139 IGLJ3
immunoglobulin lambda joining 3
chr18_+_19826734 0.138 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr9_-_21375258 0.137 NM_000605
IFNA2
interferon, alpha 2
chr5_+_127012611 0.136 NM_001048252
CTXN3
cortexin 3
chr6_+_25760352 0.133 NM_006998
SCGN
secretagogin, EF-hand calcium binding protein
chr16_-_24850163 0.127 ARHGAP17
Rho GTPase activating protein 17
chr3_-_115380539 0.126 NM_000796
NM_033663
DRD3

dopamine receptor D3

chr6_+_73133152 0.124 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr2_-_135498716 0.124 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr11_+_5714253 0.122 NM_001005180
OR56B1
olfactory receptor, family 56, subfamily B, member 1
chr15_+_46285789 0.120 NM_000338
NM_001184832
SLC12A1

solute carrier family 12 (sodium/potassium/chloride transporters), member 1

chr17_+_38247493 0.119 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr17_-_36403910 0.117 NM_033185
KRTAP3-3
keratin associated protein 3-3
chr8_-_13018123 0.117 NM_001164271
DLC1
deleted in liver cancer 1
chr3_+_123279439 0.115 NM_006889
CD86
CD86 molecule
chr10_-_23673777 0.115 NM_153714
C10orf67
chromosome 10 open reading frame 67
chrX_+_135106578 0.113 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr15_+_42815851 0.113 NM_080745
NM_182985
TRIM69

tripartite motif containing 69

chr11_+_56862395 0.113 NM_002559
P2RX3
purinergic receptor P2X, ligand-gated ion channel, 3
chr1_-_84099261 0.113


chr6_+_28032997 0.112 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr1_-_157313179 0.111 NM_004833
AIM2
absent in melanoma 2
chr4_+_187227302 0.108 NM_003265
TLR3
toll-like receptor 3
chr10_-_75071498 0.107 NM_021245
MYOZ1
myozenin 1
chr7_+_143287952 0.104 NM_012369
OR2F1
olfactory receptor, family 2, subfamily F, member 1
chr11_-_16387001 0.104 NM_001145811
SOX6
SRY (sex determining region Y)-box 6
chr19_+_10689725 0.104 NM_001005360
NM_001005361
NM_001005362
NM_001190716
NM_004945
DNM2




dynamin 2




chr15_+_64481270 0.102 MAP2K1
mitogen-activated protein kinase kinase 1
chr12_-_119961143 0.102 NM_003733
NM_198213
OASL

2'-5'-oligoadenylate synthetase-like

chr6_-_25044156 0.101 FAM65B
family with sequence similarity 65, member B
chr2_-_113310796 0.100 NM_000576
IL1B
interleukin 1, beta
chr4_-_87247829 0.100 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr5_-_9683462 0.098 NM_019599
TAS2R1
taste receptor, type 2, member 1
chr10_+_80942362 0.098 NM_001099692
EIF5AL1
eukaryotic translation initiation factor 5A-like 1
chr7_-_107230867 0.097 NM_000111
SLC26A3
solute carrier family 26, member 3
chr12_+_8866416 0.094 NM_144670
A2ML1
alpha-2-macroglobulin-like 1
chr1_-_203657803 0.094 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr11_+_71524403 0.094 NM_000804
FOLR3
folate receptor 3 (gamma)
chr19_+_9222605 0.092 NM_001079935
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr21_+_39745649 0.092 NM_007341
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr3_-_152449591 0.092 NM_001081455
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr12_+_48310593 0.090 NM_001031698
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr19_+_10689763 0.090 DNM2
dynamin 2
chr5_+_128328685 0.089 SLC27A6
solute carrier family 27 (fatty acid transporter), member 6
chr19_-_3723208 0.089 NM_032753
RAX2
retina and anterior neural fold homeobox 2
chr1_+_151498802 0.089 NM_000427
LOR
loricrin
chr3_-_150952944 0.088 NM_016094
COMMD2
COMM domain containing 2
chr3_-_150952920 0.087 COMMD2
COMM domain containing 2
chr11_-_7804094 0.087 NM_153445
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr9_+_4782974 0.086 RCL1
RNA terminal phosphate cyclase-like 1
chr17_+_18700385 0.078 PRPSAP2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr12_+_61645361 0.077 RPL14
ribosomal protein L14
chr12_+_84792203 0.076 NM_006183
NTS
neurotensin
chr1_+_144152864 0.075 TXNIP
thioredoxin interacting protein
chr12_-_45506001 0.075 NM_001143824
NM_018018
SLC38A4

solute carrier family 38, member 4

chr19_+_10689772 0.074 DNM2
dynamin 2
chr1_+_245818284 0.074 NM_001001915
OR2G2
olfactory receptor, family 2, subfamily G, member 2
chr9_-_21197141 0.072 NM_002171
IFNA10
interferon, alpha 10
chr19_+_10689750 0.071 DNM2
dynamin 2
chr6_-_32665409 0.069 NM_002124
HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr18_-_29882555 0.069 NM_001198549
NOL4
nucleolar protein 4
chr7_+_128365482 0.068 NM_032643
IRF5
interferon regulatory factor 5
chr13_+_78068246 0.067 LOC780529
hypothetical LOC780529
chr9_-_124280025 0.066 NM_001004451
OR1J1
olfactory receptor, family 1, subfamily J, member 1
chr2_+_204440753 0.066 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr12_-_119826433 0.064 NM_139015
SPPL3
signal peptide peptidase 3
chr5_+_147695314 0.064 NM_001040433
SPINK9
serine peptidase inhibitor, Kazal type 9
chr7_-_50596238 0.063 NM_000790
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr12_-_101115677 0.062 NM_002674
PMCH
pro-melanin-concentrating hormone
chr3_+_58459131 0.062 NM_153331
KCTD6
potassium channel tetramerisation domain containing 6
chr5_-_160044844 0.062 ATP10B
ATPase, class V, type 10B
chr1_-_23393808 0.061 NM_000864
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D
chr5_+_140733664 0.061 NM_018919
NM_032086
PCDHGA6

protocadherin gamma subfamily A, 6

chr1_-_196776697 0.061 NM_133262
NM_133326
ATP6V1G3

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

chr9_-_123961870 0.061 NM_014222
NDUFA8
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
chr1_-_148854503 0.060


chr16_+_68516401 0.060 NM_199424
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr18_+_41558089 0.060 NM_001128588
NM_001146036
NM_015865
SLC14A1


solute carrier family 14 (urea transporter), member 1 (Kidd blood group)


chr17_-_39094787 0.060 NM_001040002
MEOX1
mesenchyme homeobox 1
chr21_-_36760594 0.059 NM_012130
CLDN14
claudin 14
chr1_-_150564302 0.058 NM_002016
FLG
filaggrin
chr15_+_70193652 0.058 NM_001166340
SENP8
SUMO/sentrin specific peptidase family member 8
chr19_-_14813688 0.056 NM_001005190
OR7A10
olfactory receptor, family 7, subfamily A, member 10
chr12_+_99274987 0.056 NM_001145288
NM_139319
SLC17A8

solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8

chr12_+_10348311 0.055 NM_001114396
KLRD1
killer cell lectin-like receptor subfamily D, member 1
chr1_-_150463292 0.055 NM_001009931
HRNR
hornerin
chr1_-_57204208 0.054 NM_000066
C8B
complement component 8, beta polypeptide
chr12_-_44670613 0.054 SCAF11
SR-related CTD-associated factor 11
chr1_+_145116168 0.054


chr20_+_9406460 0.054 PLCB4
phospholipase C, beta 4
chr13_+_51334117 0.054 NM_031290
CCDC70
coiled-coil domain containing 70
chr4_+_42590038 0.053 NM_001080476
GRXCR1
glutaredoxin, cysteine rich 1
chr6_-_25940247 0.053 NM_005074
SLC17A1
solute carrier family 17 (sodium phosphate), member 1
chr6_-_27988152 0.052 NM_033057
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr3_+_14691609 0.052 NM_001184957
NM_001184958
NM_032137
C3orf20


chromosome 3 open reading frame 20


chr22_+_36422940 0.052 NM_001039141
TRIOBP
TRIO and F-actin binding protein
chr13_-_97916768 0.052 STK24
serine/threonine kinase 24
chr6_+_54281161 0.052 NM_014464
TINAG
tubulointerstitial nephritis antigen
chr12_-_66839589 0.051 NM_000619
IFNG
interferon, gamma
chr11_+_60223622 0.050 NM_031457
MS4A8B
membrane-spanning 4-domains, subfamily A, member 8B
chr1_+_157167965 0.050 NM_152501
NM_198928
NM_198929
NM_198930
PYHIN1



pyrin and HIN domain family, member 1



chr20_+_19985289 0.050 NM_001167816
C20orf26
chromosome 20 open reading frame 26
chr5_+_180726874 0.050 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr7_+_129771865 0.049 NM_001127441
NM_001127442
NM_080385
CPA5


carboxypeptidase A5


chr21_-_33107813 0.049 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr17_-_44154878 0.049 NM_032391
PRAC
prostate cancer susceptibility candidate
chr8_-_38577891 0.048


chr4_-_100575313 0.048 NM_001166504
NM_000673
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr3_+_99484421 0.048 NM_001005482
OR5H2
olfactory receptor, family 5, subfamily H, member 2
chr17_-_36409632 0.047 NM_031959
KRTAP3-2
keratin associated protein 3-2
chr17_+_36647795 0.047 NM_031963
KRTAP9-8
keratin associated protein 9-8
chr1_+_151117421 0.047 NM_030663
SMCP
sperm mitochondria-associated cysteine-rich protein
chr4_+_68995761 0.046 NM_014058
TMPRSS11E
transmembrane protease, serine 11E
chr11_+_73339011 0.045 NM_153614
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr18_+_54681040 0.045 NM_018181
ZNF532
zinc finger protein 532
chr12_-_44670584 0.045 SCAF11
SR-related CTD-associated factor 11
chr11_+_5862076 0.045 NM_001005165
OR52E4
olfactory receptor, family 52, subfamily E, member 4
chr21_+_30910614 0.045 NM_181615
KRTAP20-1
keratin associated protein 20-1
chr19_-_22744623 0.044 NM_001080409
ZNF99
zinc finger protein 99
chr14_-_79747592 0.043 NM_001007023
DIO2
deiodinase, iodothyronine, type II
chr6_+_12622286 0.043


chr1_-_171442937 0.042 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr7_-_38279757 0.042 NM_001003799
NM_001003806
TARP

TRGV9
TCR gamma alternate reading frame protein

T cell receptor gamma variable 9
chr1_+_227506751 0.041 NM_006542
SPHAR
S-phase response (cyclin related)
chr3_+_153014550 0.041 NM_001086
AADAC
arylacetamide deacetylase (esterase)
chr5_+_132460779 0.041 HSPA4
heat shock 70kDa protein 4
chr2_+_102136833 0.041 NM_000877
IL1R1
interleukin 1 receptor, type I
chr19_-_4510713 0.040 SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr9_+_124463665 0.040 NM_001005236
OR1L1
olfactory receptor, family 1, subfamily L, member 1
chr6_-_32227695 0.040 NM_030651
PRRT1
proline-rich transmembrane protein 1
chr1_+_157246305 0.040 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr3_-_56784634 0.040 NM_001128616
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr2_+_61243132 0.040 NM_001143959
C2orf74
chromosome 2 open reading frame 74
chr12_-_16649211 0.040 LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_-_83644054 0.040 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr1_+_169747788 0.040 PRRC2C
proline-rich coiled-coil 2C
chr15_-_56093477 0.039 NM_170697
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr1_-_7835681 0.039 NM_006786
UTS2
urotensin 2
chr6_+_47857733 0.039 NM_181744
OPN5
opsin 5
chr9_+_92629525 0.038 NM_001174167
SYK
spleen tyrosine kinase
chr21_+_44941514 0.037 NM_198699
KRTAP10-12
keratin associated protein 10-12
chr7_+_63411813 0.037 ZNF736
zinc finger protein 736
chr2_-_207291364 0.037 NM_001093730
DYTN
dystrotelin

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.90 4.63e-07 GO:0007606 sensory perception of chemical stimulus
4.06 8.13e-07 GO:0007608 sensory perception of smell
2.17 1.76e-05 GO:0003008 system process
2.79 2.88e-05 GO:0007600 sensory perception
2.28 6.80e-05 GO:0050877 neurological system process
3.13 2.87e-03 GO:0050776 regulation of immune response
2.47 7.94e-03 GO:0006955 immune response
2.09 8.44e-03 GO:0002376 immune system process
26.10 1.21e-02 GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production
2.41 3.72e-02 GO:0002682 regulation of immune system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.48 1.62e-03 GO:0005886 plasma membrane
1.46 3.01e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.25 5.41e-08 GO:0004984 olfactory receptor activity
2.84 1.31e-06 GO:0004930 G-protein coupled receptor activity
2.27 2.80e-05 GO:0004888 transmembrane receptor activity
2.04 4.71e-05 GO:0004872 receptor activity
1.82 5.57e-04 GO:0004871 signal transducer activity
1.82 5.57e-04 GO:0060089 molecular transducer activity