• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities
• All promoters sorted by FOV

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: HSF1,2.p2

Z-value: 1.364

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr21_+_30724442	1.439	NM_181600	KRTAP13-4	keratin associated protein 13-4
chr11_-_118799452	1.250	NM_006288	THY1	Thy-1 cell surface antigen
chr6_+_129245978	1.219	NM_000426 NM_001079823	LAMA2	laminin, alpha 2
chr5_-_135318420	1.097	NM_002302	LECT2	leukocyte cell-derived chemotaxin 2
chr10_+_95838801	1.081	NM_001165979	PLCE1	phospholipase C, epsilon 1
chr4_+_77575276	1.002	NM_020859	SHROOM3	shroom family member 3
chr1_+_66570683	0.982		PDE4B	phosphodiesterase 4B, cAMP-specific
chr6_+_32817140	0.974	NM_020056	HLA-DQA2	major histocompatibility complex, class II, DQ alpha 2
chr1_-_102234959	0.961		OLFM3	olfactomedin 3
chr9_-_72926333	0.925	NM_001007471	TRPM3	transient receptor potential cation channel, subfamily M, member 3
chr12_+_8557402	0.898	NM_080387	CLEC4D	C-type lectin domain family 4, member D
chr12_-_21818881	0.894	NM_004982	KCNJ8	potassium inwardly-rectifying channel, subfamily J, member 8
chr19_-_47638890	0.881	NM_198477	CXCL17	chemokine (C-X-C motif) ligand 17
chr7_-_27133163	0.825	NM_153631	HOXA3	homeobox A3
chr1_-_148155986	0.822	NM_014849	SV2A	synaptic vesicle glycoprotein 2A
chr5_-_42211112	0.779
chr1_-_182273451	0.774	NM_015101	GLT25D2	glycosyltransferase 25 domain containing 2
chr13_+_45174446	0.766	NM_152719	SPERT	spermatid associated
chr6_-_32839244	0.728	NM_001198858	HLA-DQB2	major histocompatibility complex, class II, DQ beta 2
chr15_+_40438989	0.723	NM_000070 NM_024344 NM_173087	CAPN3	calpain 3, (p94)
chr7_-_75876830	0.694	NM_080744	SRCRB4D	scavenger receptor cysteine rich domain containing, group B (4 domains)
chr5_+_79366746	0.686	NM_003248	THBS4	thrombospondin 4
chrX_+_106050261	0.674	NM_020384	CLDN2	claudin 2
chr1_-_102235377	0.671	NM_058170	OLFM3	olfactomedin 3
chr3_+_191588354	0.669	NM_006580	CLDN16	claudin 16
chr10_-_28611020	0.664	NM_173496	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr6_-_40003295	0.657	NM_005943	MOCS1	molybdenum cofactor synthesis 1
chr9_-_90983501	0.655	NM_016848	SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr1_-_163680941	0.650	NM_006917	RXRG	retinoid X receptor, gamma
chr8_-_125649926	0.646		MTSS1	metastasis suppressor 1
chr9_+_831689	0.645	NM_021951	DMRT1	doublesex and mab-3 related transcription factor 1
chr9_-_68492023	0.639	NM_001085476	FOXD4L6	forkhead box D4-like 6
chr18_+_29573152	0.631		ASXL3	additional sex combs like 3 (Drosophila)
chr11_+_59806661	0.629	NM_024021	MS4A4A	membrane-spanning 4-domains, subfamily A, member 4
chr8_+_87947788	0.626	NM_173538	CNBD1	cyclic nucleotide binding domain containing 1
chr2_-_21084911	0.621		APOB	apolipoprotein B (including Ag(x) antigen)
chr1_-_173979292	0.618	NM_003285	TNR	tenascin R (restrictin, janusin)
chr8_-_82522175	0.615	NM_002677	PMP2	peripheral myelin protein 2
chr9_-_90983195	0.613		SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr1_-_203657803	0.597	NM_001001552 NM_001199050 NM_001199051 NM_001199052	LEMD1	LEM domain containing 1
chr5_-_135729062	0.586	NM_001167576 NM_001167577 NM_020389	TRPC7	transient receptor potential cation channel, subfamily C, member 7
chr7_+_97199206	0.585	NM_003182 NM_013996 NM_013997 NM_013998	TAC1	tachykinin, precursor 1
chr15_+_39739864	0.582	NM_001080541 NM_001164273	MGA	MAX gene associated
chr2_-_39040981	0.580		LOC375196	hypothetical LOC375196
chr2_-_217268492	0.578	NM_000599	IGFBP5	insulin-like growth factor binding protein 5
chr15_+_74416129	0.573		ISL2	ISL LIM homeobox 2
chr5_-_135259403	0.572	NM_000590	IL9	interleukin 9
chr6_+_159510416	0.570	NM_032532	FNDC1	fibronectin type III domain containing 1
chr1_+_157246305	0.564	NM_005531	IFI16	interferon, gamma-inducible protein 16
chr3_+_125586241	0.563		KALRN	kalirin, RhoGEF kinase
chr18_+_54013575	0.558	NM_001144970	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr10_+_115501202	0.555	NM_001193434 NM_001193435 NM_024889	C10orf81	chromosome 10 open reading frame 81
chr15_+_39739933	0.555		MGA	MAX gene associated
chr11_-_35503720	0.547	NM_001001991 NM_015430	PAMR1	peptidase domain containing associated with muscle regeneration 1
chr7_-_80386258	0.547		SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr1_-_182273114	0.542		GLT25D2	glycosyltransferase 25 domain containing 2
chr14_+_71468902	0.537		RGS6	regulator of G-protein signaling 6
chr11_-_102219450	0.537	NM_002422	MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr5_+_140762551	0.536	NM_018921 NM_032089	PCDHGA9	protocadherin gamma subfamily A, 9
chr1_+_114295289	0.536	NM_198269	HIPK1	homeodomain interacting protein kinase 1
chr7_-_131983986	0.527	NM_181775	PLXNA4	plexin A4
chrX_-_131989963	0.526	NM_031907	USP26	ubiquitin specific peptidase 26
chr4_-_20914626	0.526	NM_147183	KCNIP4	Kv channel interacting protein 4
chr18_+_30427279	0.526	NM_001128175 NM_001198938 NM_001198939 NM_001198940	DTNA	dystrobrevin, alpha
chr4_+_93444572	0.523	NM_001510	GRID2	glutamate receptor, ionotropic, delta 2
chr21_+_30690165	0.518	NM_181599	KRTAP13-1	keratin associated protein 13-1
chr12_-_113326085	0.508	NM_080718	TBX5	T-box 5
chr4_-_85638410	0.508	NM_006168	NKX6-1	NK6 homeobox 1
chr14_-_59167139	0.502		RTN1	reticulon 1
chr14_-_59167284	0.501		RTN1	reticulon 1
chr5_-_22889487	0.497	NM_004061	CDH12	cadherin 12, type 2 (N-cadherin 2)
chr12_-_43555607	0.491	NM_001145109	NELL2	NEL-like 2 (chicken)
chr2_-_21084077	0.491		APOB	apolipoprotein B (including Ag(x) antigen)
chrX_-_110542040	0.489	NM_178151 NM_001195553 NM_178152 NM_178153	DCX	doublecortin
chr15_+_36014748	0.488	NM_152453	TMCO5A	transmembrane and coiled-coil domains 5A
chr11_+_45825244	0.485	NM_001127457	CRY2	cryptochrome 2 (photolyase-like)
chr18_+_27425727	0.479	NM_000371	TTR	transthyretin
chr7_-_80386602	0.475	NM_006379	SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chrX_+_46825179	0.471		RGN	regucalcin (senescence marker protein-30)
chr14_-_59407103	0.470	NM_021136	RTN1	reticulon 1
chr5_-_95044415	0.463	NM_031952	SPATA9	spermatogenesis associated 9
chr4_+_114433551	0.459		ANK2	ankyrin 2, neuronal
chr10_+_82268433	0.457		TSPAN14	tetraspanin 14
chr11_-_27700180	0.455	NM_170731	BDNF	brain-derived neurotrophic factor
chr2_+_113973130	0.454	NM_012184	FOXD4L1	forkhead box D4-like 1
chr7_-_19778928	0.454	NM_152774	TMEM196	transmembrane protein 196
chr3_-_124893875	0.453		MYLK	myosin light chain kinase
chr8_-_13018123	0.449	NM_001164271	DLC1	deleted in liver cancer 1
chr19_+_13066956	0.448		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr2_+_214984705	0.447	NM_001080500	VWC2L	von Willebrand factor C domain containing protein 2-like
chr14_-_56346849	0.441	NM_021728	OTX2	orthodenticle homeobox 2
chr8_-_93181091	0.439	NM_001198628	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_-_117193505	0.439	NM_001085480	FAM162B	family with sequence similarity 162, member B
chr13_+_23042722	0.436	NM_148957	TNFRSF19	tumor necrosis factor receptor superfamily, member 19
chr17_+_17339059	0.433
chr7_-_96489884	0.430
chr4_-_101658094	0.425	NM_001159694 NM_016242	EMCN	endomucin
chr3_+_149930656	0.417	NM_032049	AGTR1	angiotensin II receptor, type 1
chr4_+_22303645	0.415	NM_001128432 NM_020973	GBA3	glucosidase, beta, acid 3 (cytosolic)
chr7_-_4867963	0.414	NM_020144	PAPOLB	poly(A) polymerase beta (testis specific)
chr19_-_53941835	0.408	NM_182575	IZUMO1	izumo sperm-egg fusion 1
chr3_+_134978615	0.408		TF	transferrin
chr19_+_56049982	0.403	NM_001030047 NM_001030048 NM_001030050 NM_001648	KLK3	kallikrein-related peptidase 3
chr14_+_88130482	0.403	NM_207662	ZC3H14	zinc finger CCCH-type containing 14
chr15_+_94670160	0.403	NM_001145155	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr3_+_12367993	0.401	NM_015869	PPARG	peroxisome proliferator-activated receptor gamma
chr14_-_59167193	0.399	NM_206852	RTN1	reticulon 1
chr5_-_22889192	0.396		CDH12	cadherin 12, type 2 (N-cadherin 2)
chrX_-_54841397	0.395	NM_198510	ITIH5L	inter-alpha (globulin) inhibitor H5-like
chr10_-_90601655	0.394	NM_144590	ANKRD22	ankyrin repeat domain 22
chr1_+_179164195	0.392
chr12_-_11230809	0.390	NM_181429	TAS2R42	taste receptor, type 2, member 42
chr12_-_24628348	0.390		C12orf67	chromosome 12 open reading frame 67
chr4_-_15686838	0.388	NM_001145849 NM_001145850 NM_001145851 NM_001145852 NM_006017	PROM1	prominin 1
chr19_-_60383280	0.387	NM_003180	SYT5	synaptotagmin V
chrX_-_52700674	0.387	NM_173358	SSX7	synovial sarcoma, X breakpoint 7
chr10_-_104587069	0.387	NM_000102	CYP17A1	cytochrome P450, family 17, subfamily A, polypeptide 1
chr11_-_113971607	0.387		FAM55D	family with sequence similarity 55, member D
chr3_-_48607596	0.384	NM_000094	COL7A1	collagen, type VII, alpha 1
chr1_+_26220852	0.384	NM_004455	EXTL1	exostoses (multiple)-like 1
chr12_+_1596482	0.383	NM_030775	WNT5B	wingless-type MMTV integration site family, member 5B
chr12_-_14612057	0.382	NM_024829	PLBD1	phospholipase B domain containing 1
chrX_-_31436335	0.382	NM_004014	DMD	dystrophin
chr6_+_29382381	0.376	NM_030946	OR14J1	olfactory receptor, family 14, subfamily J, member 1
chr7_-_11643113	0.375		THSD7A	thrombospondin, type I, domain containing 7A
chr9_-_69468634	0.372	NM_001126334	FOXD4L5	forkhead box D4-like 5
chr5_-_22248630	0.372		CDH12	cadherin 12, type 2 (N-cadherin 2)
chr6_-_127822227	0.372	NM_014702	KIAA0408	KIAA0408
chr11_-_123685871	0.371	NM_001002917	OR8D1	olfactory receptor, family 8, subfamily D, member 1
chr2_+_143603368	0.368	NM_018460	ARHGAP15	Rho GTPase activating protein 15
chr15_+_90815910	0.367	NM_153040	C15orf32	chromosome 15 open reading frame 32
chr18_-_28606839	0.367	NM_020805	KLHL14	kelch-like 14 (Drosophila)
chr7_+_30927439	0.364	NM_001185060 NM_001185061 NM_001185062	AQP1	aquaporin 1 (Colton blood group)
chr17_+_11726943	0.362	NM_004662	DNAH9	dynein, axonemal, heavy chain 9
chr18_-_30057512	0.360	NM_001198546 NM_001198548 NM_003787	NOL4	nucleolar protein 4
chr12_-_14611820	0.360		PLBD1	phospholipase B domain containing 1
chr4_-_122304925	0.359	NM_024873	TNIP3	TNFAIP3 interacting protein 3
chr6_-_127882192	0.357	NM_001012279	C6orf174	chromosome 6 open reading frame 174
chr11_+_123405506	0.355	NM_001004464	OR10G8	olfactory receptor, family 10, subfamily G, member 8
chr17_-_25685175	0.353	NM_206832	TMIGD1	transmembrane and immunoglobulin domain containing 1
chr4_-_123092358	0.352	NM_001130698	TRPC3	transient receptor potential cation channel, subfamily C, member 3
chr11_-_113971681	0.351	NM_001077639 NM_017678	FAM55D	family with sequence similarity 55, member D
chr1_+_117098579	0.350	NM_001767	CD2	CD2 molecule
chr7_+_18296569	0.349		HDAC9	histone deacetylase 9
chr3_-_152144712	0.347	NM_052995	CLRN1	clarin 1
chr4_+_96980261	0.346	NM_005390	PDHA2	pyruvate dehydrogenase (lipoamide) alpha 2
chr3_+_160269734	0.342	NM_001197113 NM_001197114 NM_001042705 NM_001042706 NM_001197100	IQCJ-SCHIP1 IQCJ	IQCJ-SCHIP1 readthrough IQ motif containing J
chr1_+_153232685	0.341	NM_018655	LENEP	lens epithelial protein
chr2_+_143603439	0.341		ARHGAP15	Rho GTPase activating protein 15
chr14_-_69616616	0.340	NM_182936 NM_001130417	SLC8A3	solute carrier family 8 (sodium/calcium exchanger), member 3
chr8_-_23768242	0.339	NM_003155	STC1	stanniocalcin 1
chr15_+_60838053	0.339		TLN2	talin 2
chr15_-_72804763	0.338	NM_000499	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1
chr10_+_90474280	0.338	NM_001080518	LIPK	lipase, family member K
chr2_+_207512522	0.338	NM_173077	CPO	carboxypeptidase O
chr3_-_13032130	0.337
chr16_+_68516401	0.336	NM_199424	WWP2	WW domain containing E3 ubiquitin protein ligase 2
chr9_-_108416	0.336	NM_207305	FOXD4	forkhead box D4
chrX_-_134798808	0.332	NM_001017438	CT45A3 CT45A4 CT45A5 CT45A6 CT45A1	cancer/testis antigen family 45, member A3 cancer/testis antigen family 45, member A4 cancer/testis antigen family 45, member A5 cancer/testis antigen family 45, member A6 cancer/testis antigen family 45, member A1
chr12_+_54106304	0.331	NM_001005183	OR6C76	olfactory receptor, family 6, subfamily C, member 76
chr22_+_44059491	0.328	NM_001167574 NM_006953	UPK3A	uroplakin 3A
chr10_-_62002672	0.328		ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr4_+_5577783	0.328	NM_005750	C4orf6	chromosome 4 open reading frame 6
chr14_-_80934523	0.328	NM_033104	STON2	stonin 2
chr3_-_9895471	0.327		CIDEC	cell death-inducing DFFA-like effector c
chr6_+_106640903	0.326		PRDM1	PR domain containing 1, with ZNF domain
chr15_+_45263517	0.326	NM_001198999	SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr7_+_137411717	0.325	NM_001190906 NM_001190907 NM_005989	AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
chr15_+_87540238	0.324		ABHD2	abhydrolase domain containing 2
chr14_-_59166976	0.324		RTN1	reticulon 1
chr5_+_127012611	0.322	NM_001048252	CTXN3	cortexin 3
chr12_-_91346054	0.322	NM_001025232	CLLU1OS	chronic lymphocytic leukemia up-regulated 1 opposite strand
chr13_+_52500830	0.321	NM_006418	OLFM4	olfactomedin 4
chr19_-_295778	0.320	NM_017550	MIER2	mesoderm induction early response 1, family member 2
chr1_+_109450116	0.319
chr15_-_79403494	0.317	NM_181900	STARD5	StAR-related lipid transfer (START) domain containing 5
chr2_+_222871109	0.316	NM_153038	CCDC140	coiled-coil domain containing 140
chr1_+_92456160	0.315	NM_001012425	C1orf146	chromosome 1 open reading frame 146
chr12_+_5473558	0.315	NM_002527	NTF3	neurotrophin 3
chr9_+_42707229	0.314	NM_001099279 NM_199244	FOXD4L2 FOXD4L4	forkhead box D4-like 2 forkhead box D4-like 4
chr11_-_65070625	0.313		LTBP3	latent transforming growth factor beta binding protein 3
chr4_-_122357104	0.312	NM_001128843	TNIP3	TNFAIP3 interacting protein 3
chr1_+_144004589	0.310	NM_001039703	NBPF10 NBPF8	neuroblastoma breakpoint family, member 10 neuroblastoma breakpoint family, member 8
chr9_+_110664366	0.309	NM_006687	ACTL7A	actin-like 7A
chr1_+_66570363	0.309	NM_001037339	PDE4B	phosphodiesterase 4B, cAMP-specific
chr3_+_45042754	0.308	NM_003278	CLEC3B	C-type lectin domain family 3, member B
chr4_-_108176901	0.308	NM_014421	DKK2	dickkopf homolog 2 (Xenopus laevis)
chr3_-_44464722	0.305
chr2_+_108604111	0.305	NM_001193484	LIMS1	LIM and senescent cell antigen-like domains 1
chr19_-_2036227	0.304		MOBKL2A	MOB1, Mps One Binder kinase activator-like 2A (yeast)
chr10_+_18280773	0.303	NM_001145195 NM_152725	SLC39A12	solute carrier family 39 (zinc transporter), member 12
chr2_+_166137091	0.302	NM_024969	CSRNP3	cysteine-serine-rich nuclear protein 3
chr9_+_70107602	0.297	NM_199135	FOXD4L3 FOXD4L6	forkhead box D4-like 3 forkhead box D4-like 6
chr8_+_24297742	0.295	NM_001145271 NM_001145272 NM_014479	ADAMDEC1	ADAM-like, decysin 1
chr3_-_42427026	0.295	NM_144634	LYZL4	lysozyme-like 4
chr3_+_46386636	0.294	NM_000579 NM_001100168	CCR5	chemokine (C-C motif) receptor 5
chrX_-_48156287	0.293	NM_001034832 NM_001040612 NM_005636 NM_175729	SSX4B SSX4	synovial sarcoma, X breakpoint 4B synovial sarcoma, X breakpoint 4
chr12_-_67643286	0.293	NM_001874	CPM	carboxypeptidase M
chr7_-_7541974	0.293	NM_001037763	COL28A1	collagen, type XXVIII, alpha 1
chr10_-_75080784	0.292	NM_024875	SYNPO2L	synaptopodin 2-like

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.25	1.30e-09	GO:0032501	multicellular organismal process
8.54	1.28e-05	GO:0048880	sensory system development
8.54	1.28e-05	GO:0048892	lateral line nerve development
8.54	1.28e-05	GO:0048895	lateral line nerve glial cell differentiation
8.54	1.28e-05	GO:0048925	lateral line system development
8.54	1.28e-05	GO:0048937	lateral line nerve glial cell development
8.54	1.28e-05	GO:0050935	iridophore differentiation
1.27	1.82e-05	GO:0007275	multicellular organismal development
1.24	1.02e-04	GO:0032502	developmental process
8.54	1.10e-04	GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching
1.41	1.40e-04	GO:0007399	nervous system development
6.26	1.52e-04	GO:0048484	enteric nervous system development
1.27	3.86e-04	GO:0048731	system development
6.99	5.65e-04	GO:0060600	dichotomous subdivision of an epithelial terminal unit
6.41	2.02e-03	GO:0048846	axon extension involved in axon guidance
5.70	2.57e-03	GO:0048485	sympathetic nervous system development
2.05	7.04e-03	GO:0032582	negative regulation of gene-specific transcription
1.22	7.50e-03	GO:0048856	anatomical structure development
2.81	7.84e-03	GO:0048762	mesenchymal cell differentiation
2.16	8.98e-03	GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter
1.28	1.45e-02	GO:0030154	cell differentiation
3.97	1.61e-02	GO:0021545	cranial nerve development
4.48	2.00e-02	GO:0030318	melanocyte differentiation
4.48	2.00e-02	GO:0050931	pigment cell differentiation
1.13	2.41e-02	GO:0050896	response to stimulus
4.10	2.43e-02	GO:0001755	neural crest cell migration
5.13	3.30e-02	GO:0030513	positive regulation of BMP signaling pathway
1.44	3.37e-02	GO:0040011	locomotion
5.70	3.50e-02	GO:0090184	positive regulation of kidney development
3.37	3.56e-02	GO:0014033	neural crest cell differentiation
3.52	3.91e-02	GO:0014032	neural crest cell development
3.70	4.11e-02	GO:0048066	developmental pigmentation
1.26	4.95e-02	GO:0048869	cellular developmental process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.53	1.55e-06	GO:0044421	extracellular region part
1.23	4.82e-06	GO:0005886	plasma membrane
1.22	1.24e-05	GO:0071944	cell periphery
1.53	1.07e-04	GO:0005615	extracellular space
1.28	1.04e-03	GO:0005576	extracellular region
1.63	1.24e-02	GO:0031012	extracellular matrix

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.37	2.17e-02	GO:0003704	specific RNA polymerase II transcription factor activity

---