Motif ID: HSF1,2.p2

Z-value: 1.364


Transcription factors associated with HSF1,2.p2:

Gene SymbolEntrez IDGene Name
HSF1 3297 heat shock transcription factor 1
HSF2 3298 heat shock transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HSF2chr6_+_122762384-0.467.1e-02Click!
HSF1chr8_+_145486052-0.136.3e-01Click!


Activity profile for motif HSF1,2.p2.

activity profile for motif HSF1,2.p2


Sorted Z-values histogram for motif HSF1,2.p2

Sorted Z-values for motif HSF1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HSF1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr21_+_30724442 1.439 NM_181600
 KRTAP13-4
keratin associated protein 13-4
chr11_-_118799452 1.250 NM_006288
 THY1
Thy-1 cell surface antigen
chr6_+_129245978 1.219 NM_000426
NM_001079823
 LAMA2

laminin, alpha 2

chr5_-_135318420 1.097 NM_002302
 LECT2
leukocyte cell-derived chemotaxin 2
chr10_+_95838801 1.081 NM_001165979
 PLCE1
phospholipase C, epsilon 1
chr4_+_77575276 1.002 NM_020859
 SHROOM3
shroom family member 3
chr1_+_66570683 0.982 PDE4B
phosphodiesterase 4B, cAMP-specific
chr6_+_32817140 0.974 NM_020056
 HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr1_-_102234959 0.961 OLFM3
olfactomedin 3
chr9_-_72926333 0.925 NM_001007471
 TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr12_+_8557402 0.898 NM_080387
 CLEC4D
C-type lectin domain family 4, member D
chr12_-_21818881 0.894 NM_004982
 KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr19_-_47638890 0.881 NM_198477
 CXCL17
chemokine (C-X-C motif) ligand 17
chr7_-_27133163 0.825 NM_153631
 HOXA3
homeobox A3
chr1_-_148155986 0.822 NM_014849
 SV2A
synaptic vesicle glycoprotein 2A
chr5_-_42211112 0.779


chr1_-_182273451 0.774 NM_015101
 GLT25D2
glycosyltransferase 25 domain containing 2
chr13_+_45174446 0.766 NM_152719
 SPERT
spermatid associated
chr6_-_32839244 0.728 NM_001198858
 HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr15_+_40438989 0.723 NM_000070
NM_024344
NM_173087
 CAPN3


calpain 3, (p94)



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
8.54 1.28e-05 GO:0048880 sensory system development
8.54 1.28e-05 GO:0048892 lateral line nerve development
8.54 1.28e-05 GO:0048895 lateral line nerve glial cell differentiation
8.54 1.28e-05 GO:0048925 lateral line system development
8.54 1.28e-05 GO:0048937 lateral line nerve glial cell development
8.54 1.28e-05 GO:0050935 iridophore differentiation
8.54 1.10e-04 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
6.99 5.65e-04 GO:0060600 dichotomous subdivision of an epithelial terminal unit
6.41 2.02e-03 GO:0048846 axon extension involved in axon guidance
6.26 1.52e-04 GO:0048484 enteric nervous system development
5.70 2.57e-03 GO:0048485 sympathetic nervous system development
5.70 3.50e-02 GO:0090184 positive regulation of kidney development
5.13 3.30e-02 GO:0030513 positive regulation of BMP signaling pathway
4.48 2.00e-02 GO:0030318 melanocyte differentiation
4.48 2.00e-02 GO:0050931 pigment cell differentiation
4.10 2.43e-02 GO:0001755 neural crest cell migration
3.97 1.61e-02 GO:0021545 cranial nerve development
3.70 4.11e-02 GO:0048066 developmental pigmentation
3.52 3.91e-02 GO:0014032 neural crest cell development
3.37 3.56e-02 GO:0014033 neural crest cell differentiation

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.63 1.24e-02 GO:0031012 extracellular matrix
1.53 1.55e-06 GO:0044421 extracellular region part
1.53 1.07e-04 GO:0005615 extracellular space
1.28 1.04e-03 GO:0005576 extracellular region
1.23 4.82e-06 GO:0005886 plasma membrane
1.22 1.24e-05 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.37 2.17e-02 GO:0003704 specific RNA polymerase II transcription factor activity