Motif ID: IKZF1.p2

Z-value: 0.996


Transcription factors associated with IKZF1.p2:

Gene SymbolEntrez IDGene Name
IKZF1 10320 IKAROS family zinc finger 1 (Ikaros)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
IKZF1chr7_+_503148010.302.6e-01Click!


Activity profile for motif IKZF1.p2.

activity profile for motif IKZF1.p2


Sorted Z-values histogram for motif IKZF1.p2

Sorted Z-values for motif IKZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of IKZF1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_95720870 1.779 LOC100288748
hypothetical LOC100288748
chr12_-_56447090 1.445 NM_000785
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr12_-_56445653 1.045 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr13_+_24152548 1.022 NM_001185085
NM_001676
ATP12A

ATPase, H+/K+ transporting, nongastric, alpha polypeptide

chr15_+_38923470 1.013 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr11_+_118259684 0.910 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr17_-_34575939 0.891 NM_001143968
ARL5C
ADP-ribosylation factor-like 5C
chr4_-_155632317 0.778 NM_001142552
NM_001142553
DCHS2

dachsous 2 (Drosophila)

chr3_+_140148765 0.755 NM_001040061
C3orf72
chromosome 3 open reading frame 72
chr3_-_140148671 0.703 NM_023067
FOXL2
forkhead box L2
chr13_-_78075683 0.681 NM_006237
POU4F1
POU class 4 homeobox 1
chr12_+_39372456 0.655 NM_001843
NM_175038
CNTN1

contactin 1

chr16_-_1971180 0.630 NM_172167
NM_172168
NOXO1

NADPH oxidase organizer 1

chr12_-_52980914 0.621 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr5_-_54504590 0.617 NM_001145734
NM_001170402
NM_152623
CDC20B


cell division cycle 20 homolog B (S. cerevisiae)


chr22_+_38720881 0.614 NM_138435
FAM83F
family with sequence similarity 83, member F
chr4_-_155631861 0.561 DCHS2
dachsous 2 (Drosophila)
chr12_-_52980984 0.543 NM_001136023
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr9_+_86473273 0.541 NM_001018064
NM_006180
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr17_+_7283412 0.516 NM_004112
FGF11
fibroblast growth factor 11
chr19_-_10558906 0.506 NM_005498
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr1_+_12627152 0.501 NM_001013630
AADACL4
arylacetamide deacetylase-like 4
chr22_-_45037882 0.498 NM_006071
PKDREJ
polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)
chr20_-_3097070 0.493 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr8_-_37916803 0.492 NM_152413
GOT1L1
glutamic-oxaloacetic transaminase 1-like 1
chr10_-_102880892 0.489 NM_001085398
TLX1NB
TLX1 neighbor
chr10_+_103976132 0.480 NM_152310
ELOVL3
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3
chr5_+_76284435 0.479 NM_001882
CRHBP
corticotropin releasing hormone binding protein
chr9_-_97319067 0.474 NM_001083602
NM_001083603
PTCH1

patched 1

chr2_+_120820140 0.473 NM_002193
INHBB
inhibin, beta B
chr1_-_71285847 0.473 NM_001126044
NM_198714
NM_198715
NM_198716
NM_198717
NM_198718
NM_198719
PTGER3






prostaglandin E receptor 3 (subtype EP3)






chr1_+_158603480 0.472 NM_005598
NHLH1
nescient helix loop helix 1
chr15_-_91432755 0.465 NM_001166287
RGMA
RGM domain family, member A
chr1_+_1971762 0.465 NM_002744
PRKCZ
protein kinase C, zeta
chr6_-_94185780 0.460 NM_004440
EPHA7
EPH receptor A7
chr19_+_12805747 0.455 MAST1
microtubule associated serine/threonine kinase 1
chr6_+_132901119 0.447 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chr20_-_1113116 0.447 NM_018354
C20orf46
chromosome 20 open reading frame 46
chr1_+_117253882 0.445 NM_020440
PTGFRN
prostaglandin F2 receptor negative regulator
chr1_-_117011824 0.440 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chrX_+_21302317 0.436 NM_001168647
NM_001168648
NM_001168649
NM_014927
CNKSR2



connector enhancer of kinase suppressor of Ras 2



chr6_+_150505849 0.435 NM_030949
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr18_+_3441589 0.432 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr7_-_87774130 0.432 NM_024636
STEAP4
STEAP family member 4
chr9_+_17568952 0.428 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr2_-_108972100 0.427 NM_022336
EDAR
ectodysplasin A receptor
chr17_+_50333021 0.425 NM_005486
TOM1L1
target of myb1 (chicken)-like 1
chr3_-_171786468 0.424 NM_020949
SLC7A14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr11_+_6216905 0.417 NM_001037329
CNGA4
cyclic nucleotide gated channel alpha 4
chr1_+_158636987 0.413 NM_020335
VANGL2
vang-like 2 (van gogh, Drosophila)
chr20_-_22978141 0.402 NM_000361
THBD
thrombomodulin
chr3_-_69517913 0.400 FRMD4B
FERM domain containing 4B
chr2_-_142605739 0.399 NM_018557
LRP1B
low density lipoprotein receptor-related protein 1B
chr19_+_17843753 0.398 NM_000453
SLC5A5
solute carrier family 5 (sodium iodide symporter), member 5
chr14_+_80491461 0.395 NM_000369
NM_001018036
NM_001142626
TSHR


thyroid stimulating hormone receptor


chr2_+_47449790 0.391 NM_002354
EPCAM
epithelial cell adhesion molecule
chr2_-_108972048 0.390 EDAR
ectodysplasin A receptor
chr4_-_109308893 0.389 NM_001130713
NM_001130714
NM_016269
LEF1


lymphoid enhancer-binding factor 1


chr19_-_38408449 0.386 NM_019849
SLC7A10
solute carrier family 7, (neutral amino acid transporter, y+ system) member 10
chr5_-_35974493 0.386 NM_001042625
NM_144647
CAPSL

calcyphosine-like

chr9_+_99655227 0.379 NM_004473
FOXE1
forkhead box E1 (thyroid transcription factor 2)
chr10_-_21502993 0.377 NEBL
nebulette
chr17_+_41424665 0.369 MAPT
microtubule-associated protein tau
chr17_-_31281398 0.367 NM_001163122
NM_001163124
NM_001163125
NM_001163130
RDM1



RAD52 motif 1



chr7_-_75876830 0.367 NM_080744
SRCRB4D
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr10_-_97190885 0.367 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr17_-_3814334 0.366 NM_005173
NM_174953
NM_174954
NM_174955
NM_174956
NM_174957
NM_174958
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr17_+_7457988 0.365 SHBG
sex hormone-binding globulin
chr15_+_69626594 0.354 THSD4
thrombospondin, type I, domain containing 4
chr6_+_54281161 0.352 NM_014464
TINAG
tubulointerstitial nephritis antigen
chr19_+_19183763 0.348 NM_004386
NCAN
neurocan
chr11_+_71580816 0.347 NM_016729
FOLR1
folate receptor 1 (adult)
chr10_-_62163083 0.346 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr16_+_23101538 0.345 NM_001039
SCNN1G
sodium channel, nonvoltage-gated 1, gamma
chr12_-_56159631 0.340 NM_001080157
ARHGAP9
Rho GTPase activating protein 9
chr19_-_49523747 0.337 ZFP112
zinc finger protein 112 homolog (mouse)
chr2_-_100088760 0.337 AFF3
AF4/FMR2 family, member 3
chr10_+_102881050 0.336 NM_001195517
NM_005521
TLX1

T-cell leukemia homeobox 1

chr7_-_92693716 0.333 NM_001039372
HEPACAM2
HEPACAM family member 2
chr14_-_47213906 0.333 NM_001113498
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr11_-_57792206 0.331 NM_207374
OR10W1
olfactory receptor, family 10, subfamily W, member 1
chrX_+_122922058 0.329 NM_001042749
STAG2
stromal antigen 2
chr10_+_44726635 0.328 NM_001123376
TMEM72
transmembrane protein 72
chr1_+_153366559 0.325 EFNA1
ephrin-A1
chr8_-_132122016 0.322 NM_001115
ADCY8
adenylate cyclase 8 (brain)
chr14_-_64416307 0.319 SPTB
spectrin, beta, erythrocytic
chr5_+_180514548 0.317 NM_206880
OR2V2
olfactory receptor, family 2, subfamily V, member 2
chr19_+_60283571 0.314 NM_017729
EPS8L1
EPS8-like 1
chr11_+_45863774 0.314 NM_005456
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr19_+_447453 0.314 NM_130760
NM_130762
MADCAM1

mucosal vascular addressin cell adhesion molecule 1

chr10_-_21503025 0.312 NM_001173484
NM_213569
NEBL

nebulette

chr3_-_69518119 0.312 NM_015123
FRMD4B
FERM domain containing 4B
chr13_+_38159172 0.310 NM_207361
FREM2
FRAS1 related extracellular matrix protein 2
chr4_+_81325447 0.310 NM_020226
PRDM8
PR domain containing 8
chr19_-_11452439 0.309 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr5_-_95794416 0.309 NM_000439
PCSK1
proprotein convertase subtilisin/kexin type 1
chr7_-_22363036 0.308 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr16_-_31135895 0.307 NM_152901
PYDC1
PYD (pyrin domain) containing 1
chr2_-_104834344 0.307 LOC100506421
hypothetical LOC100506421
chr3_+_131547048 0.305 NM_153264
COL6A5
collagen, type VI, alpha 5
chr10_-_21826211 0.305 NM_001010911
C10orf114
chromosome 10 open reading frame 114
chr5_+_140690387 0.305 NM_018912
NM_031993
PCDHGA1

protocadherin gamma subfamily A, 1

chr18_-_26935883 0.299 NM_004949
NM_024422
DSC2

desmocollin 2

chr10_-_21826192 0.299 C10orf114
chromosome 10 open reading frame 114
chr3_+_35697432 0.297 NM_198399
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr14_+_78815406 0.297 NM_001105250
NM_138970
NRXN3

neurexin 3

chr17_-_57295451 0.296 NM_032043
BRIP1
BRCA1 interacting protein C-terminal helicase 1
chr17_+_45401560 0.293 NM_138281
DLX4
distal-less homeobox 4
chr20_+_41621079 0.291 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr3_-_185578621 0.289 NM_000460
NM_001177597
NM_001177598
THPO


thrombopoietin


chr20_+_19141364 0.287 SLC24A3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr14_+_23575460 0.287 NM_001082488
DHRS4L1
dehydrogenase/reductase (SDR family) member 4 like 1
chr15_-_38908197 0.286 NM_001130143
NM_017726
PPP1R14D

protein phosphatase 1, regulatory (inhibitor) subunit 14D

chr8_+_95722516 0.286 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr19_+_40431122 0.284 LSR
lipolysis stimulated lipoprotein receptor
chr17_-_53973177 0.283 NM_001198713
SEPT4
septin 4
chr9_+_8848130 0.283


chr21_+_42512271 0.283 NM_004915
NM_016818
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr8_+_95722575 0.283 ESRP1
epithelial splicing regulatory protein 1
chr9_-_33437527 0.282 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr11_+_22646229 0.282 NM_177553
GAS2
growth arrest-specific 2
chr7_-_16471817 0.280 NM_015464
SOSTDC1
sclerostin domain containing 1
chr19_+_1397268 0.279 APC2
adenomatosis polyposis coli 2
chr14_-_23107106 0.278 NM_003917
AP1G2
adaptor-related protein complex 1, gamma 2 subunit
chr8_+_21956335 0.277 NM_003867
FGF17
fibroblast growth factor 17
chr17_-_37586716 0.277 NM_012285
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr12_-_47545816 0.276 NM_014470
RND1
Rho family GTPase 1
chr7_-_126679540 0.275 NM_001127323
GRM8
glutamate receptor, metabotropic 8
chr10_+_94823636 0.275 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr20_+_41621119 0.273 SGK2
serum/glucocorticoid regulated kinase 2
chr17_+_7289564 0.272 CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr6_+_126112588 0.271 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr15_-_87679046 0.270 POLG
polymerase (DNA directed), gamma
chr9_+_33667169 0.268


chr15_-_40236061 0.266 NM_213600
PLA2G4F
phospholipase A2, group IVF
chr17_-_58877276 0.265 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr7_+_156496360 0.264 LOC645249
hypothetical LOC645249
chr1_+_26389638 0.264 NM_198137
CATSPER4
cation channel, sperm associated 4
chr15_-_39593285 0.264 NM_001135685
NM_002344
NM_206961
LTK


leukocyte receptor tyrosine kinase


chr10_-_116154212 0.261 AFAP1L2
actin filament associated protein 1-like 2
chr3_+_143925904 0.259 NM_003304
TRPC1
transient receptor potential cation channel, subfamily C, member 1
chr11_-_10630408 0.259 NM_001098579
MRVI1
murine retrovirus integration site 1 homolog
chr10_-_21825879 0.258 C10orf114
chromosome 10 open reading frame 114
chr9_-_126573349 0.257 NM_001489
NM_033334
NR6A1

nuclear receptor subfamily 6, group A, member 1

chr1_-_2451543 0.256 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr4_+_81475897 0.256 NM_152770
C4orf22
chromosome 4 open reading frame 22
chr16_+_66128843 0.255 NM_001193524
FAM65A
family with sequence similarity 65, member A
chr18_+_46340400 0.255 NM_002747
MAPK4
mitogen-activated protein kinase 4
chr2_+_17585462 0.254 VSNL1
visinin-like 1
chr4_-_176970895 0.254 GPM6A
glycoprotein M6A
chr13_-_37341859 0.253 NM_001135955
NM_001135956
NM_001135957
NM_001135958
NM_003306
NM_016179
TRPC4





transient receptor potential cation channel, subfamily C, member 4





chr9_+_138810610 0.253 NM_001039374
KIAA1984
KIAA1984
chr20_+_13150417 0.252 NM_080826
ISM1
isthmin 1 homolog (zebrafish)
chr5_-_180560535 0.252 NM_203297
TRIM7
tripartite motif containing 7
chr12_-_49708279 0.251 NM_001174125
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr8_+_124263932 0.250 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr2_-_72228427 0.250 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr19_-_19245022 0.248 NM_001001524
TM6SF2
transmembrane 6 superfamily member 2
chr5_-_131591380 0.246 NM_001017974
NM_001142598
NM_001142599
P4HA2


prolyl 4-hydroxylase, alpha polypeptide II


chr13_-_26232777 0.246 NM_005288
GPR12
G protein-coupled receptor 12
chr8_-_145881968 0.242 ARHGAP39
Rho GTPase activating protein 39
chr16_-_65510230 0.241 NM_004062
CDH16
cadherin 16, KSP-cadherin
chr12_+_52618815 0.240 NM_017410
HOXC13
homeobox C13
chr21_+_33364316 0.240 NM_138983
OLIG1
oligodendrocyte transcription factor 1
chr19_+_10242763 0.239 ICAM1
intercellular adhesion molecule 1
chr16_-_695719 0.238 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr22_-_29866339 0.238 NM_015715
PLA2G3
phospholipase A2, group III
chr8_-_79880095 0.237 NM_000880
IL7
interleukin 7
chr4_-_17392232 0.237 NM_015688
FAM184B
family with sequence similarity 184, member B
chr14_+_22422270 0.236 NM_173527
REM2
RAS (RAD and GEM)-like GTP binding 2
chr18_+_53865455 0.235 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr6_-_2696152 0.235 NM_001012418
MYLK4
myosin light chain kinase family, member 4
chr14_+_67069668 0.235 NM_020715
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr1_-_1171964 0.234 NM_001014980
FAM132A
family with sequence similarity 132, member A
chr2_-_227372574 0.233 IRS1
insulin receptor substrate 1
chr20_+_44070946 0.232 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr11_+_3622933 0.231 NM_004314
ART1
ADP-ribosyltransferase 1
chr14_+_22845851 0.227 NM_004050
BCL2L2-PABPN1
BCL2L2
BCL2L2-PABPN1 read-through transcript
BCL2-like 2
chr11_+_63815348 0.227 NM_033310
KCNK4
potassium channel, subfamily K, member 4
chr12_-_53044495 0.225 NM_020370
GPR84
G protein-coupled receptor 84
chr13_-_45654296 0.223 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr4_-_176971175 0.223 NM_201591
GPM6A
glycoprotein M6A
chr20_-_24986501 0.223 ACSS1
acyl-CoA synthetase short-chain family member 1
chr13_-_98202884 0.222 NM_005073
SLC15A1
solute carrier family 15 (oligopeptide transporter), member 1
chr14_+_23527866 0.221 NM_198083
DHRS4
DHRS4L2
dehydrogenase/reductase (SDR family) member 4
dehydrogenase/reductase (SDR family) member 4 like 2
chr11_-_64582568 0.221 NM_005468
NAALADL1
N-acetylated alpha-linked acidic dipeptidase-like 1
chr11_-_64484184 0.220 NM_001037225
C11orf85
chromosome 11 open reading frame 85
chr19_+_10388448 0.219 PDE4A
phosphodiesterase 4A, cAMP-specific
chr12_-_55168168 0.219 NM_013267
GLS2
glutaminase 2 (liver, mitochondrial)
chr18_-_6404900 0.218 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr19_+_60580015 0.217 NM_139172
TMEM190
transmembrane protein 190
chr1_-_27582368 0.216 NM_207397
CD164L2
CD164 sialomucin-like 2
chr17_+_35277942 0.215 NM_198844
NM_199321
ZPBP2

zona pellucida binding protein 2

chr3_+_32834513 0.213 NM_001039111
TRIM71
tripartite motif containing 71
chr17_-_24425342 0.212 TIAF1
TGFB1-induced anti-apoptotic factor 1
chr14_+_23508922 0.212 NM_001193636
NM_001193637
NM_001193635
DHRS4L2


DHRS4L1
dehydrogenase/reductase (SDR family) member 4 like 2


dehydrogenase/reductase (SDR family) member 4 like 1
chr9_-_34652629 0.211 NM_006664
CCL27
chemokine (C-C motif) ligand 27
chr22_+_36531246 0.211 H1F0
H1 histone family, member 0
chr16_+_55261226 0.210 NM_005951
MT1H
metallothionein 1H
chr10_+_105026773 0.210 NM_032727
INA
internexin neuronal intermediate filament protein, alpha

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.12 3.17e-10 GO:0009987 cellular process
1.14 7.71e-03 GO:0044237 cellular metabolic process
1.87 4.25e-02 GO:0051129 negative regulation of cellular component organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 1.02e-02 GO:0044444 cytoplasmic part
1.24 3.73e-02 GO:0005829 cytosol

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 5.55e-04 GO:0005515 protein binding
1.07 7.68e-03 GO:0005488 binding