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• Activity deltas table
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Motif ID: IRF1,2,7.p3

Z-value: 2.439

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_+_34521945	4.391		SRP54	signal recognition particle 54kDa
chr12_+_111900650	3.766	NM_001032731 NM_002535 NM_016817	OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr9_-_32516164	3.542	NM_014314	DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr6_-_46997579	3.366	NM_001098518	GPR116	G protein-coupled receptor 116
chr14_+_34521854	3.130	NM_001146282 NM_003136	SRP54	signal recognition particle 54kDa
chr6_+_26473376	3.073	NM_001197247 NM_001197249 NM_007047 NM_001197248	BTN3A2	butyrophilin, subfamily 3, member A2
chr20_+_1194959	2.993	NM_014723	SNPH	syntaphilin
chr14_+_31100330	2.985	NM_025152	NUBPL	nucleotide binding protein-like
chr13_-_42464301	2.959	NM_001002264 NM_033255	EPSTI1	epithelial stromal interaction 1 (breast)
chr6_+_26510443	2.858	NM_001145008 NM_001145009 NM_007048 NM_194441	BTN3A1	butyrophilin, subfamily 3, member A1
chr6_+_26548678	2.789	NM_006994 NM_197974	BTN3A3	butyrophilin, subfamily 3, member A3
chr20_-_55628852	2.661	NM_001160417 NM_001160418 NM_001160419 NM_030776	ZBP1	Z-DNA binding protein 1
chr2_-_70329067	2.627	NM_022037 NM_022173	TIA1	TIA1 cytotoxic granule-associated RNA binding protein
chr2_-_1905508	2.500		MYT1L	myelin transcription factor 1-like
chr12_+_27568311	2.458	NM_001198915 NM_001198916 NM_003622 NM_177444	PPFIBP1	PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr2_+_122229590	2.444	NM_004622	TSN	translin
chr20_-_5048443	2.436	NM_182649	PCNA	proliferating cell nuclear antigen
chr16_+_55580910	2.429	NM_032206	NLRC5	NLR family, CARD domain containing 5
chr2_-_142605739	2.407	NM_018557	LRP1B	low density lipoprotein receptor-related protein 1B
chr7_+_154351087	2.393		LOC100132707	hypothetical LOC100132707
chr10_+_101532544	2.313		ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr7_-_92615593	2.306	NM_152703	SAMD9L	sterile alpha motif domain containing 9-like
chr16_+_10878539	2.297	NM_000246	CIITA	class II, major histocompatibility complex, transactivator
chr17_+_38719371	2.245	NM_145041	TMEM106A FLJ77644	transmembrane protein 106A hypothetical LOC728772
chr17_+_44263370	2.195	NM_005831	CALCOCO2	calcium binding and coiled-coil domain 2
chr10_+_101532450	2.195	NM_000392	ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr6_+_37081387	2.155	NM_173558	FGD2	FYVE, RhoGEF and PH domain containing 2
chr1_+_234624266	2.149	NM_145861	EDARADD	EDAR-associated death domain
chr2_-_230792844	2.141	NM_004509 NM_004510 NM_080424	SP110	SP110 nuclear body protein
chr4_-_169476391	2.092	NM_017631	DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr6_-_30289092	1.981	NM_003449	TRIM26	tripartite motif containing 26
chr12_+_4628521	1.927	NM_005002	NDUFA9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
chr2_-_68143618	1.921		C1D	C1D nuclear receptor corepressor
chr10_+_63478974	1.900		ARID5B	AT rich interactive domain 5B (MRF1-like)
chr17_-_41018291	1.799
chr4_+_187227302	1.787	NM_003265	TLR3	toll-like receptor 3
chr12_+_25096472	1.767	NM_006152	LRMP	lymphoid-restricted membrane protein
chr14_-_34252695	1.746	NM_021914	CFL2	cofilin 2 (muscle)
chr2_-_112358204	1.704	NM_022662	ANAPC1	anaphase promoting complex subunit 1
chr8_+_101232014	1.700	NM_005034	POLR2K	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr2_+_6935246	1.699	NM_080657	RSAD2	radical S-adenosyl methionine domain containing 2
chr14_-_34253473	1.677	NM_138638	CFL2	cofilin 2 (muscle)
chr4_+_88147107	1.654	NM_005935	AFF1	AF4/FMR2 family, member 1
chr4_+_144654526	1.640
chr12_+_25096755	1.621		LRMP	lymphoid-restricted membrane protein
chr10_+_92970487	1.618		PCGF5	polycomb group ring finger 5
chr2_+_178986617	1.605
chr13_-_33148899	1.602		STARD13	StAR-related lipid transfer (START) domain containing 13
chr9_-_122852356	1.561	NM_001735	C5	complement component 5
chr7_-_134845363	1.558	NM_001008225 NM_001190847 NM_001190848 NM_001190849 NM_001190850 NM_013316	CNOT4	CCR4-NOT transcription complex, subunit 4
chr17_+_18320822	1.552	NM_001040078	LGALS9B LGALS9C	lectin, galactoside-binding, soluble, 9B lectin, galactoside-binding, soluble, 9C
chr2_+_169637255	1.548	NM_001142270	DHRS9	dehydrogenase/reductase (SDR family) member 9
chrX_+_77041612	1.532	NM_001866	COX7B	cytochrome c oxidase subunit VIIb
chr12_+_38905053	1.522	NM_198578	LRRK2	leucine-rich repeat kinase 2
chr6_+_29902734	1.515	NM_002127	HLA-G	major histocompatibility complex, class I, G
chr22_+_34374358	1.505	NM_030641	APOL6	apolipoprotein L, 6
chr16_+_22011362	1.502	NM_173615	VWA3A	von Willebrand factor A domain containing 3A
chr2_-_68143662	1.465	NM_001190263 NM_001190265 NM_006333 NM_173177	C1D	C1D nuclear receptor corepressor
chr2_+_33555182	1.440		RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr21_+_42807052	1.438		SLC37A1	solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr8_+_79740813	1.437	NM_016010	FAM164A	family with sequence similarity 164, member A
chr17_+_70092651	1.437	NM_152460	C17orf77	chromosome 17 open reading frame 77
chr12_-_9913199	1.436		CLEC2B	C-type lectin domain family 2, member B
chr19_+_35555158	1.429	NM_014717	ZNF536	zinc finger protein 536
chr14_-_69953433	1.422	NM_018373	SYNJ2BP	synaptojanin 2 binding protein
chr4_-_100359353	1.419	NM_000672 NM_001102470	ADH6	alcohol dehydrogenase 6 (class V)
chr17_-_44022595	1.414		HOXB3	homeobox B3
chr5_+_36642424	1.410		SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr10_+_92970302	1.391	NM_032373	PCGF5	polycomb group ring finger 5
chr2_-_101134146	1.381	NM_001102426	TBC1D8	TBC1 domain family, member 8 (with GRAM domain)
chr2_+_190014432	1.381		WDR75	WD repeat domain 75
chr6_-_138231006	1.378
chr6_-_133161318	1.371	NM_052831	C6orf192	chromosome 6 open reading frame 192
chr8_-_17797127	1.356	NM_147203 NM_201553 NM_004467 NM_201552	FGL1	fibrinogen-like 1
chr2_-_112358013	1.350		ANAPC1	anaphase promoting complex subunit 1
chr17_-_30783631	1.350	NM_018042	SLFN12	schlafen family member 12
chr4_+_89597257	1.348	NM_016323	HERC5	hect domain and RLD 5
chr11_+_18244383	1.334	NM_000331 NM_001178006 NM_199161	SAA1	serum amyloid A1
chr11_-_18226743	1.301	NM_001127380 NM_030754	SAA2	serum amyloid A2
chr2_-_55774451	1.295	NM_033109	PNPT1	polyribonucleotide nucleotidyltransferase 1
chr1_+_110254755	1.292	NM_000757 NM_172210 NM_172211 NM_172212	CSF1	colony stimulating factor 1 (macrophage)
chr5_-_95184121	1.291		GLRX	glutaredoxin (thioltransferase)
chr1_+_149165438	1.289	NM_001145415 NM_012432	SETDB1	SET domain, bifurcated 1
chr16_-_18845223	1.288	NM_015092	SMG1	SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr1_-_180824967	1.269		RNASEL	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
chr2_-_151826504	1.267	NM_198557	RBM43	RNA binding motif protein 43
chr1_+_87368044	1.267		LOC339524	hypothetical LOC339524
chr6_-_133126278	1.266	NM_078488	VNN2	vanin 2
chr3_+_114733907	1.266	NM_017699	SIDT1	SID1 transmembrane family, member 1
chr3_-_102888090	1.266	NM_000986	RPL24	ribosomal protein L24
chr6_-_31432543	1.250		HLA-B	major histocompatibility complex, class I, B
chr22_+_34374421	1.248		APOL6	apolipoprotein L, 6
chr17_-_57295451	1.246	NM_032043	BRIP1	BRCA1 interacting protein C-terminal helicase 1
chr6_-_24827265	1.236	NM_030939	C6orf62	chromosome 6 open reading frame 62
chr3_-_69381995	1.231		FRMD4B	FERM domain containing 4B
chr22_+_25155220	1.225	NM_020437	ASPHD2	aspartate beta-hydroxylase domain containing 2
chr22_-_21204597	1.225	NM_080740	ZNF280A	zinc finger protein 280A
chr19_+_49361054	1.219	NM_001146220 NM_001032373 NM_001032374 NM_015919 NM_001032372	ZNF226	zinc finger protein 226
chr8_-_143864933	1.215	NM_003695	LY6D	lymphocyte antigen 6 complex, locus D
chr12_+_111860384	1.201		OAS3	2'-5'-oligoadenylate synthetase 3, 100kDa
chr11_-_62363551	1.197		WDR74	WD repeat domain 74
chr19_-_51909416	1.197	NM_001079882	PRKD2	protein kinase D2
chr16_-_11257539	1.191	NM_003745	SOCS1	suppressor of cytokine signaling 1
chr2_+_190014403	1.191	NM_032168	WDR75	WD repeat domain 75
chr1_-_247086686	1.166	NM_030645	SH3BP5L	SH3-binding domain protein 5-like
chr6_+_20642665	1.161	NM_017774	CDKAL1	CDK5 regulatory subunit associated protein 1-like 1
chr11_-_104344473	1.157	NM_001225	CASP4	caspase 4, apoptosis-related cysteine peptidase
chr2_+_201806410	1.149	NM_001080124 NM_001228 NM_033355 NM_033358	CASP8	caspase 8, apoptosis-related cysteine peptidase
chr11_+_28088406	1.147		METTL15	methyltransferase like 15
chr6_+_20510019	1.144	NM_001949	E2F3	E2F transcription factor 3
chr5_+_36642213	1.140	NM_001166696 NM_004172	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_150993299	1.138	NM_001144960	C3orf16	chromosome 3 open reading frame 16
chr6_+_26195426	1.136	NM_000410 NM_139003 NM_139004 NM_139006 NM_139007 NM_139008 NM_139009 NM_139010 NM_139011	HFE	hemochromatosis
chr6_+_17501589	1.134	NM_006366	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)
chr4_-_40212670	1.132	NM_019027	RBM47	RNA binding motif protein 47
chr6_-_121697305	1.129	NM_152730	C6orf170	chromosome 6 open reading frame 170
chr17_+_76988134	1.126	NM_001080519	BAHCC1	BAH domain and coiled-coil containing 1
chr8_+_22075112	1.116	NM_001172357 NM_001172410 NM_003018	SFTPC	surfactant protein C
chr5_+_56507029	1.104	NM_001127235	GPBP1	GC-rich promoter binding protein 1
chr19_+_17377502	1.101		LOC100507535	hypothetical LOC100507535
chr11_+_7463175	1.098	NM_198474	OLFML1	olfactomedin-like 1
chr14_+_93646831	1.096	NM_001130080 NM_005532	IFI27	interferon, alpha-inducible protein 27
chr12_-_4628436	1.096		AKAP3	A kinase (PRKA) anchor protein 3
chr6_-_48186868	1.086		C6orf138	chromosome 6 open reading frame 138
chr5_-_159730196	1.079	NM_031908	C1QTNF2	C1q and tumor necrosis factor related protein 2
chr5_-_95184221	1.073	NM_001118890 NM_002064	GLRX	glutaredoxin (thioltransferase)
chr22_+_38903825	1.073	NM_001162501 NM_015088	TNRC6B	trinucleotide repeat containing 6B
chr20_+_13924263	1.072		MACROD2	MACRO domain containing 2
chr2_+_85665041	1.053	NM_006634	VAMP5	vesicle-associated membrane protein 5 (myobrevin)
chr16_+_48616593	1.052	NM_153261	TMEM188	transmembrane protein 188
chr8_-_95343696	1.047		GEM	GTP binding protein overexpressed in skeletal muscle
chr6_+_37509028	1.038		FTSJD2	FtsJ methyltransferase domain containing 2
chr14_-_34169047	1.035	NM_021249 NM_152233	SNX6	sorting nexin 6
chr3_+_139388770	1.028	NM_014154 NM_015396 NM_213654	ARMC8	armadillo repeat containing 8
chr14_-_22549168	1.014	NM_001130706 NM_001130708 NM_021944	C14orf93	chromosome 14 open reading frame 93
chr10_+_82290554	1.007	NM_001145719	SH2D4B	SH2 domain containing 4B
chr2_-_162883062	0.996	NM_022168	IFIH1	interferon induced with helicase C domain 1
chr1_-_13546097	0.990	NM_001024661 NM_001099854	PRAMEF13 PRAMEF14	PRAME family member 13 PRAME family member 14
chr15_+_67094087	0.985	NM_001184779 NM_024505	NOX5	NADPH oxidase, EF-hand calcium binding domain 5
chr13_-_40533072	0.980		ELF1	E74-like factor 1 (ets domain transcription factor)
chr6_+_6533932	0.978	NM_004271	LY86	lymphocyte antigen 86
chr17_-_51155073	0.977	NM_018286	TMEM100	transmembrane protein 100
chr6_-_170704251	0.975		PSMB1	proteasome (prosome, macropain) subunit, beta type, 1
chr15_+_82945223	0.973	NM_001007072 NM_017894 NM_181877	ZSCAN2	zinc finger and SCAN domain containing 2
chr6_+_32929902	0.972	NM_002800	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chr14_+_72595055	0.972		RBM25	RNA binding motif protein 25
chr2_+_69822609	0.969	NM_001153	ANXA4	annexin A4
chr14_-_34168911	0.965		SNX6	sorting nexin 6
chr6_+_37508830	0.957	NM_015050	FTSJD2	FtsJ methyltransferase domain containing 2
chr9_+_5440455	0.942	NM_014143	CD274	CD274 molecule
chr2_+_230900121	0.940	NM_138402	SP140L	SP140 nuclear body protein-like
chr10_+_91082218	0.936	NM_001031683	IFIT3	interferon-induced protein with tetratricopeptide repeats 3
chr2_-_151854379	0.931		NMI	N-myc (and STAT) interactor
chr6_-_150253729	0.920	NM_139165	RAET1E	retinoic acid early transcript 1E
chr10_+_115429622	0.916		CASP7	caspase 7, apoptosis-related cysteine peptidase
chr12_-_8584658	0.915	NM_014358	CLEC4E	C-type lectin domain family 4, member E
chr1_+_234625338	0.913	NM_080738	EDARADD	EDAR-associated death domain
chr11_-_64520964	0.912	NM_138456	BATF2	basic leucine zipper transcription factor, ATF-like 2
chr6_-_170704304	0.901	NM_002793	PSMB1	proteasome (prosome, macropain) subunit, beta type, 1
chr22_+_34979118	0.900		APOL1	apolipoprotein L, 1
chr20_+_226200	0.898	NM_033089	ZCCHC3	zinc finger, CCHC domain containing 3
chr11_+_63060848	0.895	NM_004585	RARRES3	retinoic acid receptor responder (tazarotene induced) 3
chr1_-_27871245	0.894		IFI6	interferon, alpha-inducible protein 6
chr6_-_110843432	0.893	NM_003649 NM_004032	DDO	D-aspartate oxidase
chr1_-_27871287	0.892		IFI6	interferon, alpha-inducible protein 6
chr22_+_17012704	0.889	NM_017414	USP18	ubiquitin specific peptidase 18
chr16_-_73292188	0.888	NM_001142497 NM_152649	MLKL	mixed lineage kinase domain-like
chr12_+_106236281	0.883	NM_001018072	BTBD11	BTB (POZ) domain containing 11
chr5_-_147191428	0.879	NM_003122	SPINK1	serine peptidase inhibitor, Kazal type 1
chr14_+_72595020	0.878		RBM25	RNA binding motif protein 25
chr4_+_89519134	0.876		HERC6	hect domain and RLD 6
chr2_-_151854619	0.874	NM_004688	NMI	N-myc (and STAT) interactor
chr6_-_32929721	0.873	NM_000593	TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr15_-_97607108	0.871	NM_001040655 NM_001040656 NM_001040657 NM_001040658 NM_001040659 NM_001040660 NM_022905	TTC23	tetratricopeptide repeat domain 23
chr6_-_32929570	0.871		TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr16_-_74239030	0.857	NM_001130089 NM_005548	KARS	lysyl-tRNA synthetase
chr11_-_62364203	0.854	NM_018093	WDR74	WD repeat domain 74
chr2_-_242449662	0.851	NM_005018	PDCD1	programmed cell death 1
chr6_+_112481970	0.839	NM_003880 NM_198239	WISP3	WNT1 inducible signaling pathway protein 3
chr7_-_76883642	0.838	NM_017439	PION	pigeon homolog (Drosophila)
chr11_-_4585947	0.838	NM_018073	TRIM68	tripartite motif containing 68
chr1_+_159462456	0.837	NM_032174	TOMM40L	translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr1_+_161558346	0.830	NM_031423 NM_145697	NUF2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr10_+_91051685	0.827	NM_001547	IFIT2	interferon-induced protein with tetratricopeptide repeats 2
chr2_+_33554824	0.824	NM_001139488	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr11_-_82289006	0.821	NM_005040 NM_199418	PRCP	prolylcarboxypeptidase (angiotensinase C)
chr19_-_17377383	0.815	NM_004335	BST2	bone marrow stromal cell antigen 2
chr17_+_53602013	0.813	NM_001004707	OR4D2	olfactory receptor, family 4, subfamily D, member 2
chr1_+_24518501	0.806	NM_001195010	GRHL3	grainyhead-like 3 (Drosophila)
chr10_+_22765996	0.804		LOC100289455	hypothetical LOC100289455
chr9_-_134271985	0.803	NM_007344	TTF1	transcription termination factor, RNA polymerase I
chr10_-_45410197	0.803	NM_001002265 NM_145021	MARCH8	membrane-associated ring finger (C3HC4) 8
chr14_-_22358752	0.799	NM_001126106	SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr18_-_13905534	0.799	NM_000529	MC2R	melanocortin 2 receptor (adrenocorticotropic hormone)
chr7_+_138469029	0.797	NM_001144920 NM_001144923 NM_024926	TTC26	tetratricopeptide repeat domain 26
chr15_-_72775378	0.797		EDC3	enhancer of mRNA decapping 3 homolog (S. cerevisiae)
chr14_+_72594985	0.797		RBM25	RNA binding motif protein 25
chr7_+_100515439	0.796	NM_030961	TRIM56	tripartite motif containing 56
chr17_-_44037332	0.793	NM_018952	HOXB6	homeobox B6
chr2_+_68855436	0.792	NM_001166276 NM_014882	ARHGAP25	Rho GTPase activating protein 25

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.87	2.51e-09	GO:0002376	immune system process
5.88	2.86e-09	GO:0034340	response to type I interferon
2.13	1.16e-08	GO:0006955	immune response
5.71	1.72e-08	GO:0060337	type I interferon-mediated signaling pathway
5.71	1.72e-08	GO:0071357	cellular response to type I interferon
2.56	2.58e-07	GO:0045087	innate immune response
5.77	3.78e-07	GO:0006521	regulation of cellular amino acid metabolic process
4.51	1.29e-06	GO:2000045	regulation of G1/S transition of mitotic cell cycle
1.89	2.84e-06	GO:0051704	multi-organism process
4.80	5.16e-06	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
5.01	5.86e-06	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
5.01	5.86e-06	GO:0072395	signal transduction involved in cell cycle checkpoint
5.01	5.86e-06	GO:0072401	signal transduction involved in DNA integrity checkpoint
5.01	5.86e-06	GO:0072404	signal transduction involved in G1/S transition checkpoint
5.01	5.86e-06	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
5.01	5.86e-06	GO:0072422	signal transduction involved in DNA damage checkpoint
5.01	5.86e-06	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
5.01	5.86e-06	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
4.73	6.89e-06	GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint
4.60	1.21e-05	GO:0051352	negative regulation of ligase activity
4.60	1.21e-05	GO:0051444	negative regulation of ubiquitin-protein ligase activity
4.39	1.26e-05	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
4.78	1.44e-05	GO:0033238	regulation of cellular amine metabolic process
4.78	1.44e-05	GO:0071158	positive regulation of cell cycle arrest
4.53	1.58e-05	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.89	1.60e-05	GO:0006952	defense response
4.33	1.63e-05	GO:0031575	mitotic cell cycle G1/S transition checkpoint
4.33	1.63e-05	GO:0071779	G1/S transition checkpoint
4.12	4.30e-05	GO:0051351	positive regulation of ligase activity
3.12	5.25e-05	GO:0031400	negative regulation of protein modification process
3.61	7.02e-05	GO:0042770	signal transduction in response to DNA damage
4.13	9.16e-05	GO:0051443	positive regulation of ubiquitin-protein ligase activity
3.93	1.06e-04	GO:0030330	DNA damage response, signal transduction by p53 class mediator
3.77	1.17e-04	GO:0051340	regulation of ligase activity
2.31	1.20e-04	GO:0044419	interspecies interaction between organisms
3.89	1.32e-04	GO:0031397	negative regulation of protein ubiquitination
4.02	1.45e-04	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
3.03	1.68e-04	GO:0009615	response to virus
2.61	1.70e-04	GO:0032269	negative regulation of cellular protein metabolic process
8.05	2.03e-04	GO:0048002	antigen processing and presentation of peptide antigen
3.76	2.48e-04	GO:0051438	regulation of ubiquitin-protein ligase activity
3.25	3.38e-04	GO:0007093	mitotic cell cycle checkpoint
3.43	3.74e-04	GO:0031398	positive regulation of protein ubiquitination
1.42	4.54e-04	GO:0006950	response to stress
3.92	4.83e-04	GO:0000216	M/G1 transition of mitotic cell cycle
9.90	4.99e-04	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
2.50	5.23e-04	GO:0051248	negative regulation of protein metabolic process
3.37	5.32e-04	GO:0051320	S phase
1.98	7.30e-04	GO:0016071	mRNA metabolic process
1.90	7.85e-04	GO:0009057	macromolecule catabolic process
2.71	8.28e-04	GO:0019221	cytokine-mediated signaling pathway
13.79	8.92e-04	GO:0019883	antigen processing and presentation of endogenous antigen
1.97	9.93e-04	GO:0044265	cellular macromolecule catabolic process
3.28	1.56e-03	GO:0000084	S phase of mitotic cell cycle
2.21	1.91e-03	GO:0044257	cellular protein catabolic process
2.28	2.21e-03	GO:0034097	response to cytokine stimulus
2.53	2.78e-03	GO:0071345	cellular response to cytokine stimulus
2.90	3.23e-03	GO:0000082	G1/S transition of mitotic cell cycle
2.85	4.24e-03	GO:0031396	regulation of protein ubiquitination
3.19	4.48e-03	GO:0000077	DNA damage checkpoint
2.15	7.10e-03	GO:0051603	proteolysis involved in cellular protein catabolic process
2.20	7.40e-03	GO:0031401	positive regulation of protein modification process
2.07	1.16e-02	GO:0030163	protein catabolic process
1.99	1.18e-02	GO:0051707	response to other organism
2.99	1.30e-02	GO:0031570	DNA integrity checkpoint
2.14	1.33e-02	GO:0006511	ubiquitin-dependent protein catabolic process
2.78	1.68e-02	GO:0010565	regulation of cellular ketone metabolic process
1.54	1.99e-02	GO:0044248	cellular catabolic process
2.10	2.17e-02	GO:0019941	modification-dependent protein catabolic process
2.09	2.54e-02	GO:0043632	modification-dependent macromolecule catabolic process
1.84	3.10e-02	GO:0009607	response to biotic stimulus
1.46	4.53e-02	GO:0009056	catabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
4.85	1.53e-06	GO:0000502	proteasome complex
8.05	2.90e-05	GO:0005839	proteasome core complex
1.13	1.47e-02	GO:0005737	cytoplasm

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
7.66	8.24e-05	GO:0004298	threonine-type endopeptidase activity
7.66	8.24e-05	GO:0070003	threonine-type peptidase activity

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