Motif ID: KLF12.p2

Z-value: 3.102


Transcription factors associated with KLF12.p2:

Gene SymbolEntrez IDGene Name
KLF12 11278 Kruppel-like factor 12

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
KLF12chr13_-_73605914-0.155.8e-01Click!


Activity profile for motif KLF12.p2.

activity profile for motif KLF12.p2


Sorted Z-values histogram for motif KLF12.p2

Sorted Z-values for motif KLF12.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF12.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_27180398 2.731 NM_018951
HOXA10
homeobox A10
chr10_+_94439658 2.505 NM_002729
HHEX
hematopoietically expressed homeobox
chr2_+_176702667 2.387 NM_019558
HOXD8
homeobox D8
chr13_-_27967215 2.215 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr3_-_193609531 2.164 NM_021032
FGF12
fibroblast growth factor 12
chrX_+_67965517 2.149 NM_004429
EFNB1
ephrin-B1
chr3_-_173648896 2.148 NM_004122
NM_198407
GHSR

growth hormone secretagogue receptor

chr10_+_106390848 2.065 NM_014978
SORCS3
sortilin-related VPS10 domain containing receptor 3
chr1_-_90955365 1.997 NM_020063
BARHL2
BarH-like homeobox 2
chr17_+_23723220 1.884 SARM1
sterile alpha and TIR motif containing 1
chrX_-_71268475 1.882 NM_001024455
RGAG4
retrotransposon gag domain containing 4
chr1_+_63561632 1.870 FOXD3
forkhead box D3
chr12_+_79625538 1.783 NM_002469
MYF6
myogenic factor 6 (herculin)
chr16_-_47873183 1.780 NM_004352
CBLN1
cerebellin 1 precursor
chr1_+_152741318 1.763 NM_001098475
NM_182499
TDRD10

tudor domain containing 10

chrX_-_111953009 1.748 NM_001113490
AMOT
angiomotin
chr6_-_33268177 1.684 NM_001163771
NM_080679
NM_080680
NM_080681
COL11A2



collagen, type XI, alpha 2



chr12_+_52665196 1.684 NM_017409
HOXC10
homeobox C10
chr1_+_16247870 1.651 NM_001165945
CLCNKB
chloride channel Kb
chr8_-_140784416 1.626 NM_016601
KCNK9
potassium channel, subfamily K, member 9
chr1_+_157441824 1.623 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr4_-_111763356 1.612 PITX2
paired-like homeodomain 2
chr17_+_23723180 1.588 SARM1
sterile alpha and TIR motif containing 1
chr3_-_130761967 1.545 PLXND1
plexin D1
chrX_-_44945025 1.544 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr1_+_63561317 1.534 NM_012183
FOXD3
forkhead box D3
chr1_+_150852910 1.519 NM_178433
LCE3B
late cornified envelope 3B
chr2_-_192767494 1.514 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr1_+_235272324 1.498 NM_001035
RYR2
ryanodine receptor 2 (cardiac)
chr18_+_30810889 1.497 NM_001143826
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr17_+_77925441 1.497 NM_018949
UTS2R
urotensin 2 receptor
chr11_-_118716244 1.405 MFRP
membrane frizzled-related protein
chr15_+_39573363 1.371 NM_002220
ITPKA
inositol 1,4,5-trisphosphate 3-kinase A
chr20_-_33705244 1.368 NM_003915
CPNE1
copine I
chr3_-_129690056 1.359 NM_001145661
GATA2
GATA binding protein 2
chr22_-_37970902 1.342 NM_002608
PDGFB
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
chr1_-_110414756 1.339 NM_006492
ALX3
ALX homeobox 3
chr12_-_79855580 1.331 LIN7A
lin-7 homolog A (C. elegans)
chr16_-_47872880 1.320


chrX_-_53367246 1.320 NM_001111125
IQSEC2
IQ motif and Sec7 domain 2
chr16_-_47872973 1.310 CBLN1
cerebellin 1 precursor
chr11_-_56846246 1.308 TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr6_+_137285071 1.297 NM_001008783
SLC35D3
solute carrier family 35, member D3
chrX_-_131918905 1.297 HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr4_+_2031036 1.290 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr15_-_70288071 1.288 PKM2
pyruvate kinase, muscle
chr11_-_1006736 1.286 MUC6
mucin 6, oligomeric mucus/gel-forming
chrX_+_136475979 1.281 NM_003413
ZIC3
Zic family member 3 (odd-paired homolog, Drosophila)
chr17_-_34084682 1.280 NM_001130677
C17orf96
chromosome 17 open reading frame 96
chr17_+_23723113 1.276 NM_015077
SARM1
sterile alpha and TIR motif containing 1
chr15_-_80123935 1.271 MEX3B
mex-3 homolog B (C. elegans)
chr1_-_86394695 1.261 NM_152890
COL24A1
collagen, type XXIV, alpha 1
chr2_-_128138435 1.249 NM_017980
LIMS2
LIM and senescent cell antigen-like domains 2
chr21_+_44530148 1.249 NM_000383
AIRE
autoimmune regulator
chr8_-_145609737 1.248 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr2_+_112372671 1.231 MERTK
c-mer proto-oncogene tyrosine kinase
chr11_-_2108035 1.221 IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_+_42128521 1.209 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr8_-_132122016 1.208 NM_001115
ADCY8
adenylate cyclase 8 (brain)
chr12_-_79855618 1.207 NM_004664
LIN7A
lin-7 homolog A (C. elegans)
chr11_+_65164963 1.201


chr11_+_65164767 1.199 SIPA1
signal-induced proliferation-associated 1
chr19_-_44386731 1.198 NM_001080468
SYCN
syncollin
chr8_+_56177567 1.197 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr10_+_106391032 1.196 SORCS3
sortilin-related VPS10 domain containing receptor 3
chr1_-_202387532 1.194 ETNK2
ethanolamine kinase 2
chr3_-_129689394 1.186 NM_001145662
GATA2
GATA binding protein 2
chr2_+_112372651 1.178 NM_006343
MERTK
c-mer proto-oncogene tyrosine kinase
chr7_-_27191287 1.168 NM_005523
HOXA11
homeobox A11
chr16_+_88169612 1.166 NM_014427
NM_153636
CPNE7

copine VII

chr4_-_155631861 1.153 DCHS2
dachsous 2 (Drosophila)
chr19_+_54886160 1.150 NM_001136052
NM_152359
CPT1C

carnitine palmitoyltransferase 1C

chr10_+_24023680 1.146 NM_001098500
KIAA1217
KIAA1217
chr14_+_103675194 1.145 KIF26A
kinesin family member 26A
chr16_+_86194075 1.141 JPH3
junctophilin 3
chr2_-_42573980 1.132 KCNG3
potassium voltage-gated channel, subfamily G, member 3
chr16_-_3783475 1.129 CREBBP
CREB binding protein
chr1_+_31823097 1.117 TINAGL1
tubulointerstitial nephritis antigen-like 1
chrX_-_69396241 1.114 NM_002565
P2RY4
pyrimidinergic receptor P2Y, G-protein coupled, 4
chr22_+_23153529 1.110 NM_000675
ADORA2A
adenosine A2a receptor
chr5_-_140663615 1.103 NM_031947
SLC25A2
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2
chr19_+_2200112 1.103 NM_000479
AMH
anti-Mullerian hormone
chr1_+_160618143 1.101 NM_001085375
C1orf226
chromosome 1 open reading frame 226
chr15_+_65904994 1.090 NM_001031807
SKOR1
SKI family transcriptional corepressor 1
chr9_+_34642125 1.086 NM_001142784
IL11RA
interleukin 11 receptor, alpha
chr11_-_118716736 1.076 C1QTNF5
MFRP
C1q and tumor necrosis factor related protein 5
membrane frizzled-related protein
chr2_-_25390266 1.076 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr2_-_228754585 1.067 NM_001142644
NM_030623
SPHKAP

SPHK1 interactor, AKAP domain containing

chr17_+_40089270 1.066 NM_001145080
C17orf104
chromosome 17 open reading frame 104
chr1_+_199108705 1.058 NM_005298
GPR25
G protein-coupled receptor 25
chr16_+_162845 1.055 NM_000517
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr6_+_108593907 1.054 NM_003269
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr10_-_105604942 1.045 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr1_+_34415139 1.038 NM_001134734
C1orf94
chromosome 1 open reading frame 94
chr11_-_66092534 1.036 NM_003793
CTSF
cathepsin F
chr20_+_34206070 1.032 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr2_+_104837004 1.029


chr2_+_24126140 1.027 FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr3_-_129694717 1.026 NM_032638
GATA2
GATA binding protein 2
chr1_-_47428190 1.023 PDZK1IP1
PDZK1 interacting protein 1
chr19_-_55912006 1.020 NM_016148
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr1_+_36160375 1.020 EIF2C1
eukaryotic translation initiation factor 2C, 1
chr7_-_27190882 1.018 HOXA11
homeobox A11
chr1_-_201583989 1.012 FMOD
fibromodulin
chrX_-_109925941 1.010 NM_001143981
NM_001143982
NM_001143983
CHRDL1


chordin-like 1


chr1_+_20751518 1.008 NM_207334
FAM43B
family with sequence similarity 43, member B
chr16_+_86194170 1.008 JPH3
junctophilin 3
chr9_+_115970599 1.008 COL27A1
collagen, type XXVII, alpha 1
chr14_+_94160046 1.007


chr2_+_24126087 1.006 NM_004116
NM_054033
FKBP1B

FK506 binding protein 1B, 12.6 kDa

chr11_-_76059435 1.005 NM_001128922
LRRC32
leucine rich repeat containing 32
chr5_+_60663842 1.002 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr1_-_201321711 1.000 MYOG
myogenin (myogenic factor 4)
chr4_-_165523856 0.991 NM_001166373
MARCH1
membrane-associated ring finger (C3HC4) 1
chr3_-_51971915 0.986 NM_033010
PCBP4
poly(rC) binding protein 4
chrX_-_135166306 0.982 NM_001173516
MAP7D3
MAP7 domain containing 3
chr4_-_108176901 0.980 NM_014421
DKK2
dickkopf homolog 2 (Xenopus laevis)
chr1_-_26245031 0.978 NM_001004434
NM_032513
SLC30A2

solute carrier family 30 (zinc transporter), member 2

chr1_+_212228482 0.977 NM_002763
PROX1
prospero homeobox 1
chr2_+_85834111 0.968 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr1_-_38285033 0.965 NM_002699
POU3F1
POU class 3 homeobox 1
chr4_+_172971149 0.964 NM_001034845
GALNTL6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr1_-_1840564 0.963 NM_178545
TMEM52
transmembrane protein 52
chrX_+_151837064 0.960 NM_001178113
ZNF185
zinc finger protein 185 (LIM domain)
chr19_-_40673185 0.951 NM_207392
KRTDAP
keratinocyte differentiation-associated protein
chr3_-_130807865 0.950 NM_015103
PLXND1
plexin D1
chr21_-_31175722 0.947 NM_175858
KRTAP11-1
keratin associated protein 11-1
chrX_-_109925648 0.945 NM_145234
CHRDL1
chordin-like 1
chr6_+_22677635 0.944 NM_138574
HDGFL1
hepatoma derived growth factor-like 1
chrX_-_62921937 0.944 NM_001173479
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chrX_-_106033202 0.938 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr11_+_64737886 0.938 NM_001004326
SLC22A20
solute carrier family 22, member 20
chr17_-_32368033 0.928


chr3_+_171619346 0.925 NM_005602
CLDN11
claudin 11
chr1_-_47428310 0.918 NM_005764
PDZK1IP1
PDZK1 interacting protein 1
chr14_-_103058568 0.912 CKB
creatine kinase, brain
chr6_+_19945578 0.912 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr3_+_213535 0.912 NM_006614
CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr18_+_48120539 0.908 NM_005215
DCC
deleted in colorectal carcinoma
chr1_-_114156429 0.906 NM_018364
RSBN1
round spermatid basic protein 1
chr5_+_88220846 0.904


chr22_-_37598176 0.900 NM_014292
CBX6
chromobox homolog 6
chr11_+_113435640 0.896 NM_006006
ZBTB16
zinc finger and BTB domain containing 16
chr1_-_201321999 0.895 NM_002479
MYOG
myogenin (myogenic factor 4)
chr5_+_145698779 0.892 NM_002700
POU4F3
POU class 4 homeobox 3
chr13_-_78075683 0.891 NM_006237
POU4F1
POU class 4 homeobox 1
chr19_-_60646041 0.887 NM_001145176
SHISA7
shisa homolog 7 (Xenopus laevis)
chrX_+_51091822 0.885 NM_153183
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr1_+_151015471 0.885 NM_178354
LCE1F
late cornified envelope 1F
chr19_+_40534284 0.882 NM_005303
FFAR1
free fatty acid receptor 1
chr17_-_77512346 0.882 NM_178493
NOTUM
notum pectinacetylesterase homolog (Drosophila)
chr22_-_42069211 0.877 NM_173050
SCUBE1
signal peptide, CUB domain, EGF-like 1
chr13_+_57105859 0.877 PCDH17
protocadherin 17
chr7_-_99365178 0.877 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr15_+_76343540 0.876 NM_018602
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr1_-_204179169 0.875 NM_052934
NM_134325
SLC26A9

solute carrier family 26, member 9

chr1_+_168899936 0.875 NM_006902
NM_022716
PRRX1

paired related homeobox 1

chr12_+_77782648 0.874 SYT1
synaptotagmin I
chr8_-_27171852 0.873 STMN4
stathmin-like 4
chr11_+_113435506 0.871 ZBTB16
zinc finger and BTB domain containing 16
chrX_-_134013644 0.867 NM_001078172
NM_001134321
FAM127B

family with sequence similarity 127, member B

chrX_+_106050261 0.867 NM_020384
CLDN2
claudin 2
chr9_-_138462384 0.865 SEC16A
SEC16 homolog A (S. cerevisiae)
chr12_+_52103905 0.863 NM_001164690
NM_001164691
NM_020547
AMHR2


anti-Mullerian hormone receptor, type II


chr1_+_1557419 0.862 NM_006983
MMP23B
matrix metallopeptidase 23B
chr10_-_44200458 0.860 NM_000609
NM_001033886
NM_001178134
NM_199168
CXCL12



chemokine (C-X-C motif) ligand 12



chr1_+_157441133 0.860 NM_002036
DARC
Duffy blood group, chemokine receptor
chr1_-_37991160 0.860 EPHA10
EPH receptor A10
chr12_+_77782579 0.860 NM_005639
SYT1
synaptotagmin I
chr9_+_94987032 0.856 NM_006648
WNK2
WNK lysine deficient protein kinase 2
chr6_+_99389300 0.855 NM_005604
POU3F2
POU class 3 homeobox 2
chr22_-_17892859 0.854 NM_001130861
NM_003277
CLDN5

claudin 5

chr3_+_185430910 0.853 NM_138345
VWA5B2
von Willebrand factor A domain containing 5B2
chr10_-_103525646 0.851 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr15_-_75694674 0.848 LINGO1
leucine rich repeat and Ig domain containing 1
chr8_+_1936549 0.847 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr20_-_3097070 0.844 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr1_+_6767968 0.840 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr15_-_76313896 0.840 NM_015162
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr1_+_154386358 0.836 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr4_-_45820686 0.834 NM_173536
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr6_-_71069347 0.834 NM_001851
COL9A1
collagen, type IX, alpha 1
chr15_-_38362078 0.831 NM_001190479
LOC100131244
hypothetical protein LOC100131244
chr11_-_1725924 0.829 NM_001170820
LOC402778
CD225 family protein FLJ76511
chr5_-_146238336 0.828 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr1_+_33124658 0.825 NM_002143
HPCA
hippocalcin
chrX_-_131181141 0.822 RAP2C
RAP2C, member of RAS oncogene family
chr5_+_76542461 0.821 NM_001029851
NM_001029852
NM_001029853
NM_001029854
NM_003719
PDE8B




phosphodiesterase 8B




chr11_+_70937113 0.814 NM_005553
KRTAP5-9
keratin associated protein 5-9
chrX_+_135079461 0.814 NM_001167819
FHL1
four and a half LIM domains 1
chr3_+_213430 0.813 CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chrX_-_139414890 0.813 NM_005634
SOX3
SRY (sex determining region Y)-box 3
chr22_-_37598115 0.812 CBX6
chromobox homolog 6
chr6_+_99389318 0.811 POU3F2
POU class 3 homeobox 2
chr3_-_117647011 0.809 LSAMP
limbic system-associated membrane protein
chr9_+_138991775 0.806 NM_000954
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr1_-_17318452 0.803 NM_007365
PADI2
peptidyl arginine deiminase, type II
chr5_+_137829065 0.803 EGR1
early growth response 1
chr21_+_33364420 0.800 OLIG1
oligodendrocyte transcription factor 1
chr5_-_132189762 0.796 NM_133456
SHROOM1
shroom family member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.43 5.20e-15 GO:0007399 nervous system development
1.25 1.23e-13 GO:0007275 multicellular organismal development
1.28 1.34e-13 GO:0048731 system development
1.24 1.36e-13 GO:0032502 developmental process
1.18 6.41e-13 GO:0032501 multicellular organismal process
1.33 1.52e-12 GO:0030154 cell differentiation
1.32 6.25e-12 GO:0048869 cellular developmental process
1.25 7.53e-12 GO:0048856 anatomical structure development
1.49 3.04e-11 GO:0022008 neurogenesis
1.50 1.15e-10 GO:0048699 generation of neurons
1.62 4.91e-09 GO:0019226 transmission of nerve impulse
1.62 4.91e-09 GO:0035637 multicellular organismal signaling
1.51 7.90e-09 GO:0030182 neuron differentiation
1.11 8.55e-08 GO:0065007 biological regulation
1.42 1.15e-07 GO:0048468 cell development
1.12 4.43e-07 GO:0050794 regulation of cellular process
1.18 7.40e-07 GO:0023052 signaling
1.33 1.00e-06 GO:0051239 regulation of multicellular organismal process
1.58 1.40e-06 GO:0007268 synaptic transmission
1.30 1.74e-06 GO:0009653 anatomical structure morphogenesis
1.49 3.08e-06 GO:0048666 neuron development
1.52 3.26e-06 GO:0007417 central nervous system development
1.11 3.90e-06 GO:0050789 regulation of biological process
1.21 6.49e-06 GO:0048518 positive regulation of biological process
1.56 6.60e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.55 7.11e-06 GO:0048812 neuron projection morphogenesis
1.41 9.20e-06 GO:0007267 cell-cell signaling
1.56 1.10e-05 GO:0007409 axonogenesis
1.50 1.55e-05 GO:0048858 cell projection morphogenesis
1.50 2.54e-05 GO:0000904 cell morphogenesis involved in differentiation
1.34 3.04e-05 GO:0007154 cell communication
1.49 3.16e-05 GO:0032990 cell part morphogenesis
1.33 4.47e-05 GO:0010646 regulation of cell communication
1.60 5.08e-05 GO:0007411 axon guidance
1.43 5.67e-05 GO:0030030 cell projection organization
1.49 6.33e-05 GO:0031175 neuron projection development
1.26 6.34e-05 GO:0023051 regulation of signaling
1.41 6.69e-05 GO:0045595 regulation of cell differentiation
1.24 1.16e-04 GO:0007166 cell surface receptor linked signaling pathway
1.20 1.49e-04 GO:0048522 positive regulation of cellular process
1.33 1.82e-04 GO:0032879 regulation of localization
1.34 2.16e-04 GO:0050793 regulation of developmental process
1.55 2.28e-04 GO:0007420 brain development
1.41 2.32e-04 GO:0032989 cellular component morphogenesis
1.42 2.87e-04 GO:0000902 cell morphogenesis
1.22 3.12e-04 GO:0048513 organ development
1.21 3.66e-04 GO:0065008 regulation of biological quality
1.56 3.75e-04 GO:0044057 regulation of system process
2.74 9.39e-04 GO:0003014 renal system process
1.15 1.21e-03 GO:0007165 signal transduction
1.32 2.87e-03 GO:0040011 locomotion
1.19 3.02e-03 GO:0048523 negative regulation of cellular process
1.05 3.46e-03 GO:0009987 cellular process
1.18 3.63e-03 GO:0048519 negative regulation of biological process
1.33 4.59e-03 GO:2000026 regulation of multicellular organismal development
1.23 7.87e-03 GO:0009966 regulation of signal transduction
1.20 7.98e-03 GO:0048583 regulation of response to stimulus
1.50 1.03e-02 GO:0060284 regulation of cell development
1.52 1.13e-02 GO:0030029 actin filament-based process
1.28 1.26e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.13 1.27e-02 GO:0051179 localization
1.55 2.01e-02 GO:0030036 actin cytoskeleton organization
1.77 2.05e-02 GO:0048705 skeletal system morphogenesis
1.20 2.27e-02 GO:0003008 system process
2.32 2.54e-02 GO:0048167 regulation of synaptic plasticity
1.28 3.05e-02 GO:0006811 ion transport
1.37 3.21e-02 GO:0006935 chemotaxis
1.37 3.21e-02 GO:0042330 taxis
1.67 3.48e-02 GO:0006813 potassium ion transport
1.34 3.63e-02 GO:0010629 negative regulation of gene expression
1.33 3.95e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.37 4.49e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.31 4.80e-02 GO:0009890 negative regulation of biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.16 1.37e-07 GO:0071944 cell periphery
1.16 1.70e-07 GO:0005886 plasma membrane
1.24 2.24e-07 GO:0044459 plasma membrane part
1.58 3.06e-07 GO:0045202 synapse
1.81 5.79e-06 GO:0030424 axon
1.53 8.92e-06 GO:0043005 neuron projection
1.61 1.30e-05 GO:0044456 synapse part
1.08 2.13e-04 GO:0016020 membrane
1.31 3.33e-04 GO:0042995 cell projection
1.32 3.39e-04 GO:0005626 insoluble fraction
1.37 5.33e-04 GO:0030054 cell junction
1.09 1.31e-03 GO:0044425 membrane part
2.03 1.66e-03 GO:0033267 axon part
1.29 2.61e-03 GO:0005624 membrane fraction
1.61 3.43e-03 GO:0030425 dendrite
2.26 4.34e-03 GO:0043197 dendritic spine
1.95 5.21e-03 GO:0014069 postsynaptic density
1.23 8.49e-03 GO:0000267 cell fraction
1.09 1.06e-02 GO:0031224 intrinsic to membrane
2.17 1.15e-02 GO:0044309 neuron spine
1.21 1.45e-02 GO:0005887 integral to plasma membrane
1.09 1.45e-02 GO:0016021 integral to membrane
1.38 1.72e-02 GO:0044463 cell projection part
1.63 1.86e-02 GO:0045211 postsynaptic membrane
1.44 2.12e-02 GO:0015629 actin cytoskeleton
1.21 2.42e-02 GO:0031226 intrinsic to plasma membrane
1.77 2.67e-02 GO:0005925 focal adhesion
2.18 4.35e-02 GO:0044306 neuron projection terminus
1.47 4.61e-02 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.56 6.14e-12 GO:0043565 sequence-specific DNA binding
1.37 3.19e-07 GO:0001071 nucleic acid binding transcription factor activity
1.37 3.19e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.29 3.00e-04 GO:0030528 transcription regulator activity
2.83 1.42e-03 GO:0008066 glutamate receptor activity
1.51 1.59e-03 GO:0022836 gated channel activity
1.43 2.32e-03 GO:0015267 channel activity
1.43 2.70e-03 GO:0022803 passive transmembrane transporter activity
1.43 3.08e-03 GO:0022838 substrate-specific channel activity
1.43 3.56e-03 GO:0005216 ion channel activity
1.52 5.43e-03 GO:0005261 cation channel activity
1.45 1.16e-02 GO:0003779 actin binding
1.72 1.71e-02 GO:0005267 potassium channel activity
1.58 1.76e-02 GO:0005244 voltage-gated ion channel activity
1.58 1.76e-02 GO:0022832 voltage-gated channel activity
1.33 2.88e-02 GO:0008092 cytoskeletal protein binding
1.27 4.63e-02 GO:0015075 ion transmembrane transporter activity