Motif ID: KLF4.p3

Z-value: 2.289


Transcription factors associated with KLF4.p3:

Gene SymbolEntrez IDGene Name
KLF4 9314 Kruppel-like factor 4 (gut)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
KLF4chr9_-_109291130-0.146.0e-01Click!


Activity profile for motif KLF4.p3.

activity profile for motif KLF4.p3


Sorted Z-values histogram for motif KLF4.p3

Sorted Z-values for motif KLF4.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF4.p3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_63965156 4.626 NM_017983
 WIPI1
WD repeat domain, phosphoinositide interacting 1
chr6_-_4080700 4.296 NM_001166010
NM_006117
NM_206836
 PECI


peroxisomal D3,D2-enoyl-CoA isomerase


chr20_-_39680405 2.792 NM_032221
 CHD6
chromodomain helicase DNA binding protein 6
chr3_-_12983959 2.603 NM_014869
 IQSEC1
IQ motif and Sec7 domain 1
chr9_-_129573330 2.576 NM_005489
 SH2D3C
SH2 domain containing 3C
chr2_-_37752272 2.556 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr17_+_58954418 2.542 NM_030779
NM_173092
 KCNH6

potassium voltage-gated channel, subfamily H (eag-related), member 6

chr17_-_46298671 2.534 TOB1
transducer of ERBB2, 1
chr20_-_51644187 2.514 ZNF217
zinc finger protein 217
chr6_+_44346457 2.351 NM_001137560
 TMEM151B
transmembrane protein 151B
chr22_-_37062114 2.307 CSNK1E
casein kinase 1, epsilon
chr2_-_36678657 2.265 NM_001042548
NM_005102
 FEZ2

fasciculation and elongation protein zeta 2 (zygin II)

chr8_-_99906944 2.196 NM_006281
 STK3
serine/threonine kinase 3
chr2_-_37752731 2.157 NM_006449
 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr14_-_104718565 2.122 NM_177533
 NUDT14
nudix (nucleoside diphosphate linked moiety X)-type motif 14
chr22_-_49050847 2.104 NM_002751
 MAPK11
mitogen-activated protein kinase 11
chr7_-_134845363 2.052 NM_001008225
NM_001190847
NM_001190848
NM_001190849
NM_001190850
NM_013316
 CNOT4





CCR4-NOT transcription complex, subunit 4





chr12_+_47498778 2.010 NM_000725
 CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr20_-_32877029 2.002 NM_014071
 NCOA6
nuclear receptor coactivator 6
chr2_-_17563186 1.968 NM_001099218
 RAD51AP2
RAD51 associated protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 91 entries
enrichment   p-value GO term description
1.67 4.92e-03 GO:0006338 chromatin remodeling
1.41 1.37e-02 GO:0016570 histone modification
1.40 2.04e-02 GO:0016569 covalent chromatin modification
1.39 2.74e-06 GO:0016568 chromatin modification
1.38 2.29e-02 GO:0044087 regulation of cellular component biogenesis
1.32 6.80e-03 GO:0070647 protein modification by small protein conjugation or removal
1.32 4.38e-02 GO:0032446 protein modification by small protein conjugation
1.31 6.39e-03 GO:0018193 peptidyl-amino acid modification
1.28 1.15e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.27 3.37e-03 GO:0006325 chromatin organization
1.26 3.51e-02 GO:0044262 cellular carbohydrate metabolic process
1.25 1.13e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.25 1.13e-03 GO:0051276 chromosome organization
1.25 2.83e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.25 3.58e-02 GO:0072358 cardiovascular system development
1.25 3.58e-02 GO:0072359 circulatory system development
1.24 2.26e-03 GO:0051254 positive regulation of RNA metabolic process
1.24 1.44e-02 GO:0044265 cellular macromolecule catabolic process
1.24 2.36e-02 GO:0070727 cellular macromolecule localization
1.23 2.07e-04 GO:0046907 intracellular transport

Gene overrepresentation in compartment category:

Showing 1 to 20 of 55 entries
enrichment   p-value GO term description
1.92 2.01e-02 GO:0032153 cell division site
1.92 2.01e-02 GO:0032155 cell division site part
1.59 1.31e-03 GO:0016585 chromatin remodeling complex
1.58 2.67e-02 GO:0034399 nuclear periphery
1.51 8.41e-03 GO:0005925 focal adhesion
1.51 4.78e-02 GO:0000790 nuclear chromatin
1.46 3.53e-02 GO:0005924 cell-substrate adherens junction
1.41 9.90e-03 GO:0005912 adherens junction
1.37 1.21e-02 GO:0030424 axon
1.37 2.24e-02 GO:0070161 anchoring junction
1.34 4.39e-02 GO:0005819 spindle
1.32 3.04e-02 GO:0016604 nuclear body
1.30 7.63e-03 GO:0015629 actin cytoskeleton
1.29 2.57e-08 GO:0044451 nucleoplasm part
1.26 1.80e-02 GO:0048471 perinuclear region of cytoplasm
1.26 2.59e-02 GO:0005815 microtubule organizing center
1.24 6.26e-11 GO:0005654 nucleoplasm
1.24 3.80e-02 GO:0043005 neuron projection
1.22 3.32e-02 GO:0000139 Golgi membrane
1.21 1.01e-14 GO:0044428 nuclear part

Gene overrepresentation in function category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
1.38 1.12e-03 GO:0019900 kinase binding
1.37 9.89e-03 GO:0019901 protein kinase binding
1.36 1.89e-04 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.34 3.03e-03 GO:0016881 acid-amino acid ligase activity
1.30 3.10e-09 GO:0019899 enzyme binding
1.29 3.36e-02 GO:0008134 transcription factor binding
1.27 9.49e-04 GO:0016874 ligase activity
1.25 1.15e-02 GO:0019904 protein domain specific binding
1.25 4.72e-02 GO:0000988 protein binding transcription factor activity
1.25 4.72e-02 GO:0000989 transcription factor binding transcription factor activity
1.19 4.15e-02 GO:0043565 sequence-specific DNA binding
1.18 1.38e-03 GO:0030528 transcription regulator activity
1.16 2.88e-02 GO:0001071 nucleic acid binding transcription factor activity
1.16 2.88e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.15 1.81e-07 GO:0000166 nucleotide binding
1.15 8.35e-04 GO:0032559 adenyl ribonucleotide binding
1.15 1.00e-03 GO:0030554 adenyl nucleotide binding
1.14 2.87e-32 GO:0005515 protein binding
1.14 6.72e-05 GO:0032553 ribonucleotide binding
1.14 6.72e-05 GO:0032555 purine ribonucleotide binding