Motif ID: LEF1_TCF7_TCF7L1,2.p2

Z-value: 1.033


Transcription factors associated with LEF1_TCF7_TCF7L1,2.p2:

Gene SymbolEntrez IDGene Name
LEF1 51176 lymphoid enhancer-binding factor 1
TCF7 6932 transcription factor 7 (T-cell specific, HMG-box)
TCF7L1 83439 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 6934 transcription factor 7-like 2 (T-cell specific, HMG-box)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF7L2chr10_+_1146999530.263.3e-01Click!
TCF7chr5_+_133478252-0.185.2e-01Click!
TCF7L1chr2_+_852138840.048.7e-01Click!
LEF1chr4_-_109308893-0.039.2e-01Click!


Activity profile for motif LEF1_TCF7_TCF7L1,2.p2.

activity profile for motif LEF1_TCF7_TCF7L1,2.p2


Sorted Z-values histogram for motif LEF1_TCF7_TCF7L1,2.p2

Sorted Z-values for motif LEF1_TCF7_TCF7L1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LEF1_TCF7_TCF7L1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_52713098 1.654 NM_018953
HOXC5
homeobox C5
chr1_-_116184846 1.447 NM_001111061
NHLH2
nescient helix loop helix 2
chr17_-_76985538 0.839


chr20_-_32363268 0.838 NM_001161766
AHCY
adenosylhomocysteinase
chr8_+_102574012 0.792 GRHL2
grainyhead-like 2 (Drosophila)
chr15_+_41672543 0.787 NM_020990
CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chr1_-_116185215 0.757 NM_005599
NHLH2
nescient helix loop helix 2
chr1_+_13784553 0.750 NM_001006624
NM_001006625
PDPN

podoplanin

chr11_-_110888273 0.710 NM_017589
BTG4
B-cell translocation gene 4
chr2_+_69093641 0.710 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr6_-_24753934 0.707 NM_001168375
NM_001168376
NM_001168374
NM_001168377
NM_014809
KIAA0319




KIAA0319




chr10_-_123346148 0.695 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr17_-_36760581 0.674 NM_004138
KRT33A
keratin 33A
chr2_+_169634330 0.662 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr2_+_17861266 0.650 NM_001105569
MSGN1
mesogenin 1
chr2_+_220017617 0.616 SPEG
SPEG complex locus
chr10_+_53744043 0.608 NM_012242
DKK1
dickkopf homolog 1 (Xenopus laevis)
chr2_+_190981257 0.604 NM_017694
MFSD6
major facilitator superfamily domain containing 6
chr2_+_135312655 0.601 NM_138326
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr12_+_10222823 0.596 NM_153022
C12orf59
chromosome 12 open reading frame 59

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.