Motif ID: LMO2.p2

Z-value: 1.324


Transcription factors associated with LMO2.p2:

Gene SymbolEntrez IDGene Name
LMO2 4005 LIM domain only 2 (rhombotin-like 1)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
LMO2chr11_-_338478340.648.1e-03Click!


Activity profile for motif LMO2.p2.

activity profile for motif LMO2.p2


Sorted Z-values histogram for motif LMO2.p2

Sorted Z-values for motif LMO2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LMO2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_3556420 3.897 NM_017818
WDR8
WD repeat domain 8
chr1_+_1062137 2.731 LOC254099
hypothetical protein LOC254099
chr9_+_967386 2.463 DMRT3
doublesex and mab-3 related transcription factor 3
chr2_+_171280944 2.372 SP5
Sp5 transcription factor
chr20_-_3097070 2.320 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr14_+_73775927 2.257 NM_182894
VSX2
visual system homeobox 2
chr10_+_94823221 2.224 NM_057157
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr19_-_7845325 1.990 NM_001190467
FLJ22184
hypothetical protein FLJ22184
chr5_-_95794416 1.893 NM_000439
PCSK1
proprotein convertase subtilisin/kexin type 1
chr8_-_144862266 1.879 NM_001162914
LOC100130274
coiled-coil domain containing 121-like
chr18_-_55091596 1.876 NM_013435
RAX
retina and anterior neural fold homeobox
chr18_-_45975163 1.863 NM_001080467
MYO5B
myosin VB
chr9_+_966963 1.860 NM_021240
DMRT3
doublesex and mab-3 related transcription factor 3
chr8_+_11599119 1.849 NM_002052
GATA4
GATA binding protein 4
chr1_+_229365296 1.839 NM_001004342
TRIM67
tripartite motif containing 67
chr3_+_138965844 1.713 SOX14
SRY (sex determining region Y)-box 14
chr3_+_54131613 1.709 CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr7_-_72822471 1.699 NM_001306
CLDN3
claudin 3
chr3_+_54131731 1.688 NM_018398
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr10_+_22674379 1.683 NM_012443
NM_172242
SPAG6

sperm associated antigen 6

chr5_+_76284435 1.666 NM_001882
CRHBP
corticotropin releasing hormone binding protein
chr9_-_96441409 1.656 FBP1
fructose-1,6-bisphosphatase 1
chr18_+_65219114 1.648 NM_152721
DOK6
docking protein 6
chr12_+_131705438 1.595 NM_012226
NM_016318
NM_170682
NM_170683
NM_174872
NM_174873
P2RX2





purinergic receptor P2X, ligand-gated ion channel, 2





chr2_+_208979800 1.594 NM_005048
PTH2R
parathyroid hormone 2 receptor
chrX_+_152562013 1.594 DUSP9
dual specificity phosphatase 9
chr8_-_17315171 1.575 MTMR7
myotubularin related protein 7
chrX_-_13866451 1.570 GPM6B
glycoprotein M6B
chr2_-_73350103 1.542 NM_001080410
FBXO41
F-box protein 41
chrX_-_13866565 1.518 NM_001001994
GPM6B
glycoprotein M6B
chr8_-_140784416 1.507 NM_016601
KCNK9
potassium channel, subfamily K, member 9
chr1_-_40555413 1.491 COL9A2
collagen, type IX, alpha 2
chr1_-_114497994 1.489 NM_205848
SYT6
synaptotagmin VI
chr3_+_129117007 1.465 KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr10_-_98935369 1.444 SLIT1
slit homolog 1 (Drosophila)
chr2_-_198359182 1.444 NM_197970
BOLL
bol, boule-like (Drosophila)
chr7_+_156491223 1.439 MNX1
motor neuron and pancreas homeobox 1
chr1_-_40555511 1.437 NM_001852
COL9A2
collagen, type IX, alpha 2
chr7_-_44331544 1.432 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr13_-_77390907 1.423 NM_001122659
NM_003991
EDNRB

endothelin receptor type B

chr17_+_5913149 1.415 WSCD1
WSC domain containing 1
chr15_+_48261649 1.414 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr17_-_8809656 1.391 NM_001142633
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr12_-_33483847 1.387 NM_198992
SYT10
synaptotagmin X
chr4_-_165523856 1.364 NM_001166373
MARCH1
membrane-associated ring finger (C3HC4) 1
chr2_-_133144094 1.362 LYPD1
LY6/PLAUR domain containing 1
chr21_-_38954433 1.357 ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr14_+_71468902 1.353 RGS6
regulator of G-protein signaling 6
chr5_-_132976121 1.343 NM_015082
FSTL4
follistatin-like 4
chr9_-_96441567 1.328 FBP1
fructose-1,6-bisphosphatase 1
chr19_-_40325194 1.318 LGI4
leucine-rich repeat LGI family, member 4
chr9_+_134447795 1.317 NM_020064
BARHL1
BarH-like homeobox 1
chr16_-_2186465 1.311 NM_020764
CASKIN1
CASK interacting protein 1
chr22_+_38720881 1.304 NM_138435
FAM83F
family with sequence similarity 83, member F
chr17_+_7495140 1.292 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr4_-_15694407 1.283 PROM1
prominin 1
chr1_+_1971762 1.265 NM_002744
PRKCZ
protein kinase C, zeta
chr19_-_11452439 1.259 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr1_+_237616457 1.258 CHRM3
cholinergic receptor, muscarinic 3
chr1_-_74912009 1.256 NM_001002912
C1orf173
chromosome 1 open reading frame 173
chr1_-_92724181 1.247 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chr2_-_241408296 1.238 NM_004321
KIF1A
kinesin family member 1A
chr17_+_36647795 1.235 NM_031963
KRTAP9-8
keratin associated protein 9-8
chr3_+_120904555 1.227 NM_033364
C3orf15
chromosome 3 open reading frame 15
chr21_+_33364316 1.213 NM_138983
OLIG1
oligodendrocyte transcription factor 1
chr15_-_50375143 1.193 NM_018728
MYO5C
myosin VC
chrX_-_13866366 1.190


chr19_-_45424403 1.187 NM_024877
CNTD2
cyclin N-terminal domain containing 2
chr2_+_222997529 1.176 NM_152386
SGPP2
sphingosine-1-phosphate phosphatase 2
chr20_-_42872295 1.161 NM_182970
RIMS4
regulating synaptic membrane exocytosis 4
chr11_+_627268 1.147 NM_000797
DRD4
dopamine receptor D4
chr13_+_112681626 1.146 NM_024979
MCF2L
MCF.2 cell line derived transforming sequence-like
chr13_+_77170470 1.137 NM_001040153
SLAIN1
SLAIN motif family, member 1
chr9_-_96441654 1.125 NM_000507
FBP1
fructose-1,6-bisphosphatase 1
chr21_+_36993860 1.118 NM_005069
NM_009586
SIM2

single-minded homolog 2 (Drosophila)

chrX_+_82649924 1.110 NM_000307
POU3F4
POU class 3 homeobox 4
chr4_-_2390050 1.096 NM_001172656
NM_001172657
NM_001172658
NM_020972
ZFYVE28



zinc finger, FYVE domain containing 28



chr4_+_82171142 1.089 NM_001201
BMP3
bone morphogenetic protein 3
chr10_-_98470164 1.088 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr2_-_219633481 1.088 NM_002181
IHH
Indian hedgehog
chr4_-_15694691 1.081 NM_001145847
NM_001145848
PROM1

prominin 1

chr13_-_78075683 1.079 NM_006237
POU4F1
POU class 4 homeobox 1
chr17_+_40089270 1.070 NM_001145080
C17orf104
chromosome 17 open reading frame 104
chr5_-_95793618 1.069 NM_001177875
PCSK1
proprotein convertase subtilisin/kexin type 1
chr5_-_146238336 1.067 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr12_-_61614930 1.067 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr4_+_3738093 1.060 NM_000683
ADRA2C
adrenergic, alpha-2C-, receptor
chr11_-_1563056 1.051 NM_001005922
KRTAP5-1
keratin associated protein 5-1
chr9_-_92444886 1.049 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr14_+_61653827 1.043 FLJ43390
hypothetical LOC646113
chr17_-_7106497 1.043 CLDN7
claudin 7
chr14_+_30413393 1.041 NM_001135058
NM_004086
COCH

coagulation factor C homolog, cochlin (Limulus polyphemus)

chr11_+_45900731 1.039 GYLTL1B
glycosyltransferase-like 1B
chr9_+_86475130 1.036 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr10_-_98935652 1.033 NM_003061
SLIT1
slit homolog 1 (Drosophila)
chr8_+_21937533 1.026 NPM2
nucleophosmin/nucleoplasmin 2
chr5_-_114543632 1.023 NM_001017397
NM_001017398
NM_018700
TRIM36


tripartite motif containing 36


chr5_-_59225377 1.021 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_47595190 1.012 NM_006574
CSPG5
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr8_-_17315386 1.012 NM_004686
MTMR7
myotubularin related protein 7
chr13_-_71338144 1.011 DACH1
dachshund homolog 1 (Drosophila)
chr19_+_59618416 1.009 NM_001005367
NM_020659
TTYH1

tweety homolog 1 (Drosophila)

chr5_-_132976094 1.004 FSTL4
follistatin-like 4
chr2_+_222997456 1.004 SGPP2
sphingosine-1-phosphate phosphatase 2
chr1_+_60053050 1.003 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr10_+_94823636 1.003 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr12_-_61615124 1.001 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr13_+_30378311 0.999 NM_032849
C13orf33
chromosome 13 open reading frame 33
chr8_+_1937711 0.990 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr20_-_26137755 0.989 LOC284801
hypothetical protein LOC284801
chr11_-_129803515 0.989 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr19_-_14177980 0.983 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr16_+_66022520 0.981 NM_000196
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr16_+_66022551 0.980 HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr10_-_135088065 0.974 NM_001012508
SPRN
shadow of prion protein homolog (zebrafish)
chr10_-_132999798 0.970 TCERG1L
transcription elongation regulator 1-like
chr5_-_1348103 0.966 NM_001193376
NM_198253
TERT

telomerase reverse transcriptase

chr16_+_972064 0.962 SOX8
SRY (sex determining region Y)-box 8
chr17_+_45405128 0.957 NM_001934
DLX4
distal-less homeobox 4
chr19_+_868285 0.955 NM_032551
KISS1R
KISS1 receptor
chr18_+_73090913 0.953 NM_001480
GALR1
galanin receptor 1
chr4_+_2390469 0.950 NM_001193282
LOC402160
hypothetical protein LOC402160
chr10_-_98935570 0.943 SLIT1
slit homolog 1 (Drosophila)
chr13_-_50315832 0.942 NM_198989
DLEU7
deleted in lymphocytic leukemia, 7
chr14_+_28306633 0.942 FOXG1
forkhead box G1
chrX_+_115481774 0.940 NM_007231
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chrX_+_23262905 0.939 NM_173495
PTCHD1
patched domain containing 1
chr2_+_73282893 0.935 NM_001134462
NOTO
notochord homeobox
chr22_-_49317408 0.935 ODF3B
outer dense fiber of sperm tails 3B
chr11_+_817584 0.929 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr14_-_103058568 0.926 CKB
creatine kinase, brain
chr9_-_90983195 0.925 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr19_+_19510098 0.923 CILP2
cartilage intermediate layer protein 2
chr1_-_92721943 0.921 NM_001127215
GFI1
growth factor independent 1 transcription repressor
chr4_-_144841277 0.919 NM_001168235
FREM3
FRAS1 related extracellular matrix 3
chr2_-_192767494 0.919 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr5_+_80292313 0.918 NM_006909
RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr1_+_12149637 0.914 NM_001066
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr1_-_92721633 0.911 GFI1
growth factor independent 1 transcription repressor
chr14_+_104402626 0.907 NM_001112726
NM_015005
KIAA0284

KIAA0284

chr15_+_45263517 0.905 NM_001198999
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr17_+_26839143 0.903 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr4_-_15694764 0.892 PROM1
prominin 1
chr5_+_80292213 0.890 RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr4_+_156349230 0.885 NM_000910
NPY2R
neuropeptide Y receptor Y2
chr2_+_137239583 0.885 THSD7B
thrombospondin, type I, domain containing 7B
chr10_+_105027431 0.885 INA
internexin neuronal intermediate filament protein, alpha
chr1_-_218168404 0.885


chr3_+_138966268 0.884 NM_004189
SOX14
SRY (sex determining region Y)-box 14
chr5_+_126654354 0.877 NM_032446
MEGF10
multiple EGF-like-domains 10
chr1_+_95355415 0.873 NM_152487
TMEM56
transmembrane protein 56
chrX_+_115481848 0.873 SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr5_+_79366746 0.870 NM_003248
THBS4
thrombospondin 4
chr3_+_161426322 0.864 LOC401097
hypothetical protein LOC401097
chr3_-_69064364 0.862 NM_001005527
NM_182522
FAM19A4

family with sequence similarity 19 (chemokine (C-C motif)-like), member A4

chr14_-_99695684 0.862 NM_206918
DEGS2
degenerative spermatocyte homolog 2, lipid desaturase (Drosophila)
chr2_-_233501069 0.861 NM_001114090
NGEF
neuronal guanine nucleotide exchange factor
chr19_+_1022208 0.859 HMHA1
histocompatibility (minor) HA-1
chr3_+_98016114 0.859 NM_001080448
EPHA6
EPH receptor A6
chr6_-_110786167 0.859 NM_001123364
C6orf186
chromosome 6 open reading frame 186
chr19_-_11550765 0.858 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr9_-_38610579 0.851 ANKRD18A
ankyrin repeat domain 18A
chr1_+_175407153 0.849 NM_021165
FAM5B
family with sequence similarity 5, member B
chr11_-_118739838 0.847 USP2
ubiquitin specific peptidase 2
chr7_-_150128331 0.846 NM_001101311
NM_001101312
NM_001101314
TMEM176B


transmembrane protein 176B


chr16_+_971808 0.845 NM_014587
SOX8
SRY (sex determining region Y)-box 8
chr9_+_17568952 0.842 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr3_-_22389126 0.840 ZNF385D
zinc finger protein 385D
chr17_+_19853200 0.838 SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr17_+_36599664 0.834 NM_001190460
KRTAP9-1
keratin associated protein 9-1
chr1_+_116181927 0.834 NHLH2
nescient helix loop helix 2
chr22_-_22511173 0.832 NM_001002862
NM_001135751
NM_198440
DERL3


Der1-like domain family, member 3


chr22_-_42069211 0.830 NM_173050
SCUBE1
signal peptide, CUB domain, EGF-like 1
chr4_+_25266532 0.830 NM_001177998
NM_006424
SLC34A2

solute carrier family 34 (sodium phosphate), member 2

chr7_-_124192265 0.826 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr18_-_42590989 0.823 NM_013305
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr8_+_17478214 0.823 NM_006207
PDGFRL
platelet-derived growth factor receptor-like
chr10_-_132999973 0.822 NM_174937
TCERG1L
transcription elongation regulator 1-like
chr19_+_6415259 0.821 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr17_-_6887965 0.814 NM_153357
SLC16A11
solute carrier family 16, member 11 (monocarboxylic acid transporter 11)
chr16_-_2330738 0.813 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr18_-_33399997 0.806 NM_001025087
NM_001025088
NM_001025089
NM_020180
CELF4



CUGBP, Elav-like family member 4



chr3_-_124650081 0.802 NM_183357
ADCY5
adenylate cyclase 5
chr7_+_140420500 0.799 NM_001195278
LOC100131199
transmembrane protein 178-like
chr14_+_103674812 0.799 NM_015656
KIF26A
kinesin family member 26A
chr3_-_13436802 0.796 NM_024923
NUP210
nucleoporin 210kDa
chr19_+_44681374 0.794 NM_016941
NM_203486
DLL3

delta-like 3 (Drosophila)

chr1_-_40027108 0.792 NM_001720
BMP8B
bone morphogenetic protein 8b
chr12_+_120944174 0.791 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr10_-_134449467 0.790 NM_177400
NKX6-2
NK6 homeobox 2
chr17_+_14145051 0.784 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chrX_-_71442488 0.783 NM_001144885
NM_001144887
CITED1

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1

chr6_+_118335381 0.782 NM_001029858
SLC35F1
solute carrier family 35, member F1
chr9_-_138757175 0.781 NM_001001712
LCN10
lipocalin 10
chr13_-_52211836 0.781 LECT1
leukocyte cell derived chemotaxin 1
chr19_+_10392128 0.780 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr19_+_7834124 0.776 EVI5L
ecotropic viral integration site 5-like
chr1_-_40027097 0.773 BMP8B
bone morphogenetic protein 8b
chr9_-_139183675 0.773


chr17_+_7495436 0.771 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.32 2.88e-13 GO:0007275 multicellular organismal development
1.30 3.61e-13 GO:0032502 developmental process
1.33 9.87e-13 GO:0048856 anatomical structure development
1.34 6.48e-12 GO:0048731 system development
1.49 1.23e-11 GO:0007399 nervous system development
1.41 1.25e-11 GO:0030154 cell differentiation
1.40 3.36e-11 GO:0048869 cellular developmental process
1.56 1.13e-08 GO:0048468 cell development
1.57 2.58e-08 GO:0048699 generation of neurons
1.55 4.06e-08 GO:0022008 neurogenesis
1.14 2.56e-07 GO:0065007 biological regulation
1.23 5.66e-07 GO:0023052 signaling
1.09 8.66e-07 GO:0009987 cellular process
1.58 1.39e-06 GO:0030182 neuron differentiation
1.36 2.23e-06 GO:0023051 regulation of signaling
1.14 6.62e-06 GO:0050794 regulation of cellular process
1.46 7.30e-06 GO:0032879 regulation of localization
1.13 1.72e-05 GO:0050789 regulation of biological process
1.42 3.09e-05 GO:0010646 regulation of cell communication
1.16 3.78e-05 GO:0032501 multicellular organismal process
1.51 5.17e-05 GO:0051049 regulation of transport
1.30 5.73e-05 GO:0048513 organ development
1.56 2.01e-04 GO:0048666 neuron development
1.73 4.87e-04 GO:0051046 regulation of secretion
1.62 5.76e-04 GO:0060341 regulation of cellular localization
1.20 6.09e-04 GO:0007165 signal transduction
1.57 7.62e-04 GO:0000904 cell morphogenesis involved in differentiation
1.31 9.08e-04 GO:0009653 anatomical structure morphogenesis
1.34 9.32e-04 GO:0051239 regulation of multicellular organismal process
1.55 1.28e-03 GO:0007417 central nervous system development
1.28 1.32e-03 GO:0007166 cell surface receptor linked signaling pathway
1.56 1.35e-03 GO:0031175 neuron projection development
1.25 2.09e-03 GO:0065008 regulation of biological quality
1.59 2.11e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.48 2.41e-03 GO:0032989 cellular component morphogenesis
1.72 3.85e-03 GO:0051960 regulation of nervous system development
1.65 4.17e-03 GO:0044057 regulation of system process
1.56 5.11e-03 GO:0048812 neuron projection morphogenesis
1.57 7.37e-03 GO:0007409 axonogenesis
1.16 7.69e-03 GO:0051716 cellular response to stimulus
2.45 7.88e-03 GO:0050770 regulation of axonogenesis
1.17 8.90e-03 GO:0051179 localization
1.46 1.10e-02 GO:0000902 cell morphogenesis
1.64 1.18e-02 GO:0060284 regulation of cell development
1.73 1.24e-02 GO:0050767 regulation of neurogenesis
1.41 1.35e-02 GO:2000026 regulation of multicellular organismal development
1.36 1.88e-02 GO:0006811 ion transport
1.47 1.98e-02 GO:0007186 G-protein coupled receptor protein signaling pathway
1.78 2.81e-02 GO:0045664 regulation of neuron differentiation
1.27 2.85e-02 GO:0065009 regulation of molecular function
3.56 3.25e-02 GO:0016338 calcium-independent cell-cell adhesion
1.42 3.86e-02 GO:0030030 cell projection organization
1.60 3.88e-02 GO:0051050 positive regulation of transport
1.36 4.25e-02 GO:0040011 locomotion
1.90 4.49e-02 GO:0046883 regulation of hormone secretion
1.27 4.49e-02 GO:0009966 regulation of signal transduction
2.93 4.77e-02 GO:0050772 positive regulation of axonogenesis
1.21 4.87e-02 GO:0042221 response to chemical stimulus
1.38 4.98e-02 GO:0007267 cell-cell signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.34 1.66e-09 GO:0044459 plasma membrane part
1.63 7.58e-08 GO:0030054 cell junction
1.19 2.03e-06 GO:0005886 plasma membrane
1.19 4.56e-06 GO:0071944 cell periphery
1.12 9.97e-06 GO:0016020 membrane
1.65 3.00e-05 GO:0045202 synapse
1.13 4.18e-05 GO:0044425 membrane part
1.72 1.42e-04 GO:0044456 synapse part
1.39 5.72e-04 GO:0005626 insoluble fraction
1.39 9.37e-04 GO:0005624 membrane fraction
1.33 1.21e-03 GO:0000267 cell fraction
1.78 2.81e-03 GO:0005911 cell-cell junction
1.11 1.15e-02 GO:0031224 intrinsic to membrane
2.10 1.70e-02 GO:0008021 synaptic vesicle
1.11 2.54e-02 GO:0016021 integral to membrane
1.46 4.38e-02 GO:0043005 neuron projection

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.44 3.90e-05 GO:0022891 substrate-specific transmembrane transporter activity
1.41 5.83e-05 GO:0022857 transmembrane transporter activity
1.33 4.52e-04 GO:0005215 transporter activity
1.45 5.37e-04 GO:0043565 sequence-specific DNA binding
1.35 1.14e-03 GO:0022892 substrate-specific transporter activity
1.41 1.35e-03 GO:0015075 ion transmembrane transporter activity
1.52 6.53e-03 GO:0022803 passive transmembrane transporter activity
1.33 7.17e-03 GO:0001071 nucleic acid binding transcription factor activity
1.33 7.17e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.51 1.02e-02 GO:0015267 channel activity
1.50 2.09e-02 GO:0005216 ion channel activity
1.50 2.36e-02 GO:0022838 substrate-specific channel activity