Motif ID: MAFB.p2

Z-value: 2.268


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAFBchr20_-_387512890.253.5e-01Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_104838177 3.513 NM_006236
POU3F3
POU class 3 homeobox 3
chr5_+_113726203 3.395 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr22_+_28206180 3.114 NM_021076
NEFH
neurofilament, heavy polypeptide
chr1_+_63561317 2.676 NM_012183
FOXD3
forkhead box D3
chr8_+_85258007 2.479 NM_001100392
NM_001100393
RALYL

RALY RNA binding protein-like

chrX_+_68641802 2.353 NM_015686
FAM155B
family with sequence similarity 155, member B
chr14_+_28305922 2.037 NM_005249
FOXG1
forkhead box G1
chr10_+_124885556 1.950 NM_001105574
HMX3
H6 family homeobox 3
chr2_+_176680251 1.925 NM_021192
HOXD11
homeobox D11
chr6_+_72653126 1.883 RIMS1
regulating synaptic membrane exocytosis 1
chr17_-_47590669 1.849 CA10
carbonic anhydrase X
chrX_+_72140076 1.793 NM_001042506
PABPC1L2B
poly(A) binding protein, cytoplasmic 1-like 2B
chr8_+_65656164 1.791 BHLHE22
basic helix-loop-helix family, member e22
chr5_+_113725914 1.790 NM_021614
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr13_-_78075683 1.710 NM_006237
POU4F1
POU class 4 homeobox 1
chr2_+_74595073 1.664 NM_016170
TLX2
T-cell leukemia homeobox 2
chr17_+_56831951 1.654 NM_005994
TBX2
T-box 2
chr16_+_1979959 1.571 NM_004209
SYNGR3
synaptogyrin 3
chr8_+_31616809 1.529 NM_013962
NRG1
neuregulin 1
chr18_+_53253775 1.511 NM_004852
ONECUT2
one cut homeobox 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 161 entries
enrichment   p-value GO term description
2.14 5.81e-03 GO:0042472 inner ear morphogenesis
1.99 1.77e-06 GO:0045165 cell fate commitment
1.89 2.48e-02 GO:0048839 inner ear development
1.87 4.76e-02 GO:0021537 telencephalon development
1.84 1.18e-11 GO:0007411 axon guidance
1.79 2.36e-04 GO:0030900 forebrain development
1.78 8.75e-13 GO:0007409 axonogenesis
1.76 1.52e-12 GO:0048667 cell morphogenesis involved in neuron differentiation
1.75 1.62e-14 GO:0000904 cell morphogenesis involved in differentiation
1.73 5.89e-03 GO:0006813 potassium ion transport
1.72 2.69e-19 GO:0030182 neuron differentiation
1.72 2.49e-11 GO:0048812 neuron projection morphogenesis
1.72 4.73e-02 GO:0060537 muscle tissue development
1.70 3.50e-12 GO:0031175 neuron projection development
1.67 2.73e-13 GO:0048666 neuron development
1.66 2.01e-20 GO:0048699 generation of neurons
1.65 3.79e-21 GO:0022008 neurogenesis
1.64 7.03e-03 GO:0045664 regulation of neuron differentiation
1.63 7.48e-10 GO:0048858 cell projection morphogenesis
1.62 1.89e-09 GO:0032990 cell part morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 37 entries
enrichment   p-value GO term description
2.12 2.62e-05 GO:0008076 voltage-gated potassium channel complex
2.12 2.62e-05 GO:0034705 potassium channel complex
1.97 1.31e-06 GO:0034703 cation channel complex
1.79 5.28e-07 GO:0034702 ion channel complex
1.65 7.97e-04 GO:0030425 dendrite
1.57 1.70e-02 GO:0030424 axon
1.54 4.68e-06 GO:0043005 neuron projection
1.50 1.87e-03 GO:0044456 synapse part
1.49 1.50e-02 GO:0005667 transcription factor complex
1.48 9.62e-05 GO:0045202 synapse
1.33 8.91e-04 GO:0044451 nucleoplasm part
1.28 8.84e-03 GO:0031410 cytoplasmic vesicle
1.28 1.34e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.27 2.39e-02 GO:0031988 membrane-bounded vesicle
1.26 3.18e-02 GO:0031982 vesicle
1.23 2.48e-03 GO:0005654 nucleoplasm
1.20 4.75e-04 GO:0031981 nuclear lumen
1.19 4.23e-07 GO:0043234 protein complex
1.18 1.11e-03 GO:0005829 cytosol
1.18 1.67e-03 GO:0044428 nuclear part

Gene overrepresentation in function category:

Showing 1 to 20 of 30 entries
enrichment   p-value GO term description
1.95 4.20e-03 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.92 1.33e-03 GO:0005249 voltage-gated potassium channel activity
1.92 1.13e-02 GO:0019199 transmembrane receptor protein kinase activity
1.85 1.29e-02 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
1.82 2.02e-04 GO:0022843 voltage-gated cation channel activity
1.80 5.78e-06 GO:0005244 voltage-gated ion channel activity
1.80 5.78e-06 GO:0022832 voltage-gated channel activity
1.79 2.24e-03 GO:0005267 potassium channel activity
1.66 6.68e-17 GO:0043565 sequence-specific DNA binding
1.61 4.70e-03 GO:0010843 promoter binding
1.58 4.45e-05 GO:0022836 gated channel activity
1.58 6.67e-03 GO:0000975 regulatory region DNA binding
1.58 6.67e-03 GO:0001067 regulatory region nucleic acid binding
1.58 6.67e-03 GO:0044212 transcription regulatory region DNA binding
1.57 7.13e-05 GO:0016564 transcription repressor activity
1.56 7.56e-05 GO:0016563 transcription activator activity
1.52 5.73e-16 GO:0030528 transcription regulator activity
1.47 8.91e-03 GO:0008134 transcription factor binding
1.43 1.23e-10 GO:0001071 nucleic acid binding transcription factor activity
1.43 1.23e-10 GO:0003700 sequence-specific DNA binding transcription factor activity