Motif ID: MAFB.p2

Z-value: 2.268


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAFBchr20_-_387512890.253.5e-01Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_104838177 3.513 NM_006236
POU3F3
POU class 3 homeobox 3
chr5_+_113726203 3.395 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr22_+_28206180 3.114 NM_021076
NEFH
neurofilament, heavy polypeptide
chr1_+_63561317 2.676 NM_012183
FOXD3
forkhead box D3
chr8_+_85258007 2.479 NM_001100392
NM_001100393
RALYL

RALY RNA binding protein-like

chrX_+_68641802 2.353 NM_015686
FAM155B
family with sequence similarity 155, member B
chr14_+_28305922 2.037 NM_005249
FOXG1
forkhead box G1
chr10_+_124885556 1.950 NM_001105574
HMX3
H6 family homeobox 3
chr2_+_176680251 1.925 NM_021192
HOXD11
homeobox D11
chr6_+_72653126 1.883 RIMS1
regulating synaptic membrane exocytosis 1
chr17_-_47590669 1.849 CA10
carbonic anhydrase X
chrX_+_72140076 1.793 NM_001042506
PABPC1L2B
poly(A) binding protein, cytoplasmic 1-like 2B
chr8_+_65656164 1.791 BHLHE22
basic helix-loop-helix family, member e22
chr5_+_113725914 1.790 NM_021614
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr13_-_78075683 1.710 NM_006237
POU4F1
POU class 4 homeobox 1
chr2_+_74595073 1.664 NM_016170
TLX2
T-cell leukemia homeobox 2
chr17_+_56831951 1.654 NM_005994
TBX2
T-box 2
chr16_+_1979959 1.571 NM_004209
SYNGR3
synaptogyrin 3
chr8_+_31616809 1.529 NM_013962
NRG1
neuregulin 1
chr18_+_53253775 1.511 NM_004852
ONECUT2
one cut homeobox 2
chr17_-_71747867 1.510 NM_052916
RNF157
ring finger protein 157
chr17_+_56832255 1.506 TBX2
T-box 2
chr16_-_47873183 1.492 NM_004352
CBLN1
cerebellin 1 precursor
chr15_-_81037554 1.397 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr6_+_72653369 1.368 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr14_-_59407103 1.354 NM_021136
RTN1
reticulon 1
chr14_+_28306633 1.328 FOXG1
forkhead box G1
chr4_-_111763655 1.314 NM_000325
PITX2
paired-like homeodomain 2
chr10_-_132999798 1.311 TCERG1L
transcription elongation regulator 1-like
chr11_-_32413635 1.261 NM_000378
NM_024424
NM_024426
WT1


Wilms tumor 1


chr3_+_85090721 1.254 NM_001167674
NM_001167675
CADM2

cell adhesion molecule 2

chr19_-_13478037 1.253 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr10_-_99780574 1.239 NM_018058
CRTAC1
cartilage acidic protein 1
chr1_+_63561632 1.234 FOXD3
forkhead box D3
chr17_-_44058612 1.233 NM_024017
HOXB9
homeobox B9
chr18_-_24010944 1.219 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr4_+_61749540 1.211 LPHN3
latrophilin 3
chr10_-_99780336 1.209 CRTAC1
cartilage acidic protein 1
chr8_+_85258056 1.201 NM_173848
RALYL
RALY RNA binding protein-like
chr7_+_7188667 1.201 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr1_-_6162669 1.182 NM_015557
CHD5
chromodomain helicase DNA binding protein 5
chr5_-_44424423 1.177 NM_004465
FGF10
fibroblast growth factor 10
chr4_-_105631915 1.172 NM_025212
CXXC4
CXXC finger protein 4
chr3_-_88190737 1.170 NM_001008390
NM_003663
CGGBP1

CGG triplet repeat binding protein 1

chr9_-_34579679 1.152 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr14_+_73775927 1.150 NM_182894
VSX2
visual system homeobox 2
chr6_+_124166767 1.144 NM_001040214
NM_153355
NKAIN2

Na+/K+ transporting ATPase interacting 2

chr15_-_50869379 1.142 NM_004498
ONECUT1
one cut homeobox 1
chr6_+_19946591 1.131


chr9_+_966963 1.125 NM_021240
DMRT3
doublesex and mab-3 related transcription factor 3
chr10_+_83625049 1.107 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr1_-_102235377 1.101 NM_058170
OLFM3
olfactomedin 3
chrX_-_72215949 1.095 NM_001012977
PABPC1L2A
PABPC1L2B
poly(A) binding protein, cytoplasmic 1-like 2A
poly(A) binding protein, cytoplasmic 1-like 2B
chr1_-_99242765 1.094 NM_001010861
NM_001037317
LPPR5

lipid phosphate phosphatase-related protein type 5

chr22_+_24895454 1.092 SEZ6L
seizure related 6 homolog (mouse)-like
chr2_-_192767494 1.088 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr2_-_42573980 1.081 KCNG3
potassium voltage-gated channel, subfamily G, member 3
chr3_+_71885890 1.077 NM_018971
GPR27
G protein-coupled receptor 27
chr4_-_74343320 1.077 NM_032217
NM_198889
ANKRD17

ankyrin repeat domain 17

chr3_-_62835601 1.075


chrX_-_74062005 1.073 NM_001008537
KIAA2022
KIAA2022
chr2_+_185171537 1.070 ZNF804A
zinc finger protein 804A
chr16_+_25610847 1.062 NM_006040
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr20_-_31495086 1.050 NM_003098
SNTA1
syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
chr14_+_37748031 1.046 SSTR1
somatostatin receptor 1
chr15_-_98699628 1.043 NM_139057
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr2_-_206659140 1.037 NM_017759
INO80D
INO80 complex subunit D
chr2_-_47650973 1.032 NM_022055
KCNK12
potassium channel, subfamily K, member 12
chr2_-_219566364 1.030 NM_005209
NM_057093
NM_057094
CRYBA2


crystallin, beta A2


chr4_-_111763356 1.023 PITX2
paired-like homeodomain 2
chr3_+_148610516 1.022 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr17_+_56832492 1.009 TBX2
T-box 2
chr12_+_93066370 1.002 NM_005761
PLXNC1
plexin C1
chr8_+_56177567 0.999 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr3_+_49566901 0.998 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr5_-_146238336 0.992 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr4_+_158361185 0.991 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr10_-_73518315 0.986 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr10_-_132999973 0.980 NM_174937
TCERG1L
transcription elongation regulator 1-like
chr12_-_79855618 0.980 NM_004664
LIN7A
lin-7 homolog A (C. elegans)
chr13_+_34414390 0.979 NM_015678
NBEA
neurobeachin
chr13_+_27264779 0.979 NM_145657
GSX1
GS homeobox 1
chr4_-_168392266 0.969 SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr14_+_37748345 0.968 SSTR1
somatostatin receptor 1
chr12_-_79855580 0.963 LIN7A
lin-7 homolog A (C. elegans)
chr1_-_102234959 0.953 OLFM3
olfactomedin 3
chr15_+_31390454 0.952 NM_001036
RYR3
ryanodine receptor 3
chr1_-_175400573 0.942 NM_004319
NM_207108
ASTN1

astrotactin 1

chr13_+_27610379 0.939 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chrX_-_107866262 0.933 NM_003604
IRS4
insulin receptor substrate 4
chr11_-_129803515 0.926 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr2_+_185171682 0.926 ZNF804A
zinc finger protein 804A
chr9_+_99656013 0.922


chr3_-_71886203 0.922 NM_001134649
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr2_+_198377561 0.912 NM_006226
PLCL1
phospholipase C-like 1
chr6_+_99389318 0.895 POU3F2
POU class 3 homeobox 2
chr13_-_71338558 0.895 DACH1
dachshund homolog 1 (Drosophila)
chr2_-_88707978 0.890 NM_004836
EIF2AK3
eukaryotic translation initiation factor 2-alpha kinase 3
chr8_+_24827181 0.879 NEFM
neurofilament, medium polypeptide
chr5_+_170779664 0.876 FGF18
fibroblast growth factor 18
chr11_-_129803712 0.873 NM_007037
ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chrX_+_21302317 0.869 NM_001168647
NM_001168648
NM_001168649
NM_014927
CNKSR2



connector enhancer of kinase suppressor of Ras 2



chr15_-_32875040 0.868 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr19_+_11510578 0.863 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr18_-_30056431 0.863 NM_001198547
NOL4
nucleolar protein 4
chr20_+_52525538 0.860 NM_018431
DOK5
docking protein 5
chr17_+_14145051 0.854 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr10_+_25504295 0.853 NM_020752
GPR158
G protein-coupled receptor 158
chr5_-_147142457 0.853 JAKMIP2
janus kinase and microtubule interacting protein 2
chr4_-_41848874 0.840 BEND4
BEN domain containing 4
chr8_-_121893468 0.840 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr7_-_27206249 0.839 NM_000522
HOXA13
homeobox A13
chr2_-_236741352 0.839 NM_001485
GBX2
gastrulation brain homeobox 2
chr4_+_147779492 0.838 NM_004575
POU4F2
POU class 4 homeobox 2
chr5_+_75734759 0.835 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chrX_+_136476353 0.833 ZIC3
Zic family member 3 (odd-paired homolog, Drosophila)
chrX_-_30237403 0.831 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr5_+_140780797 0.830 PCDHGA11
protocadherin gamma subfamily A, 11
chr5_-_147142444 0.827 NM_014790
JAKMIP2
janus kinase and microtubule interacting protein 2
chr11_-_75599433 0.820 WNT11
wingless-type MMTV integration site family, member 11
chr7_-_103417198 0.817 NM_005045
NM_173054
RELN

reelin

chr8_+_24827173 0.817 NM_005382
NEFM
neurofilament, medium polypeptide
chr18_+_74841262 0.810 NM_171999
SALL3
sal-like 3 (Drosophila)
chr1_+_175407153 0.807 NM_021165
FAM5B
family with sequence similarity 5, member B
chr14_-_26136799 0.805 NM_002515
NM_006489
NM_006491
NOVA1


neuro-oncological ventral antigen 1


chr13_-_27441143 0.803 CDX2
caudal type homeobox 2
chr6_+_1257674 0.795 NM_033260
FOXQ1
forkhead box Q1
chr2_-_227371698 0.795 NM_005544
IRS1
insulin receptor substrate 1
chr4_-_17632456 0.792 NM_001166139
NM_153686
LCORL

ligand dependent nuclear receptor corepressor-like

chr17_+_25467948 0.789 NM_032141
CCDC55
coiled-coil domain containing 55
chr3_-_124650081 0.786 NM_183357
ADCY5
adenylate cyclase 5
chrX_-_1470862 0.769 NM_001636
SLC25A6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chrX_+_147389825 0.767 NM_001169122
NM_001169123
NM_001169124
NM_001169125
NM_002025
AFF2




AF4/FMR2 family, member 2




chr15_-_81113676 0.764 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr6_+_110406890 0.763 NM_005284
GPR6
G protein-coupled receptor 6
chr5_+_140780720 0.761 NM_018914
NM_032091
NM_032092
PCDHGA11


protocadherin gamma subfamily A, 11


chr4_-_174686918 0.760 HAND2
heart and neural crest derivatives expressed 2
chr17_+_56884560 0.760 TBX4
T-box 4
chr11_+_17714070 0.759 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr16_+_65840275 0.754 NM_004594
SLC9A5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr8_+_85258257 0.753 RALYL
RALY RNA binding protein-like
chr4_-_85638410 0.753 NM_006168
NKX6-1
NK6 homeobox 1
chr12_-_78852815 0.752 PPP1R12A
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr11_-_132318741 0.751 OPCML
opioid binding protein/cell adhesion molecule-like
chr14_-_62581656 0.747 NM_139318
NM_172375
KCNH5

potassium voltage-gated channel, subfamily H (eag-related), member 5

chr5_-_63293301 0.747 NM_000524
HTR1A
5-hydroxytryptamine (serotonin) receptor 1A
chr19_-_16599986 0.747 NM_004831
MED26
mediator complex subunit 26
chrX_+_151557292 0.747 NM_018558
GABRQ
gamma-aminobutyric acid (GABA) receptor, theta
chr11_+_108798084 0.742 C11orf87
chromosome 11 open reading frame 87
chr9_-_16717887 0.742 BNC2
basonuclin 2
chr11_+_65945050 0.742 NM_178864
NPAS4
neuronal PAS domain protein 4
chr11_+_22171150 0.737 NM_001142649
NM_213599
ANO5

anoctamin 5

chr1_-_239587007 0.734 RGS7
regulator of G-protein signaling 7
chr2_-_219881937 0.727 PTPRN
protein tyrosine phosphatase, receptor type, N
chr20_-_32163743 0.726 NM_003908
EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr1_-_111018798 0.726 KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr6_+_72653420 0.724 RIMS1
regulating synaptic membrane exocytosis 1
chr8_+_1937711 0.723 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr20_+_20296744 0.723 NM_002196
INSM1
insulinoma-associated 1
chr4_+_3738093 0.718 NM_000683
ADRA2C
adrenergic, alpha-2C-, receptor
chr10_-_73518284 0.715 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr4_-_174687104 0.715 HAND2
heart and neural crest derivatives expressed 2
chr5_-_147142368 0.714 JAKMIP2
janus kinase and microtubule interacting protein 2
chr10_-_73518269 0.708 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr15_+_41597097 0.705 NM_002373
MAP1A
microtubule-associated protein 1A
chr3_+_3816079 0.703 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr4_-_44145266 0.702 KCTD8
potassium channel tetramerisation domain containing 8
chr3_-_10724715 0.702 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr7_+_33911636 0.700 NM_133468
BMPER
BMP binding endothelial regulator
chr1_-_175400665 0.698 ASTN1
astrotactin 1
chr17_-_25642962 0.696 NM_000386
BLMH
bleomycin hydrolase
chr22_+_24895424 0.696 NM_001184773
NM_001184774
NM_001184775
NM_001184776
NM_001184777
NM_021115
SEZ6L





seizure related 6 homolog (mouse)-like





chr9_+_967386 0.695 DMRT3
doublesex and mab-3 related transcription factor 3
chr19_+_2427122 0.695 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chrX_+_23262905 0.694 NM_173495
PTCHD1
patched domain containing 1
chr13_-_50315832 0.692 NM_198989
DLEU7
deleted in lymphocytic leukemia, 7
chr8_-_132122016 0.692 NM_001115
ADCY8
adenylate cyclase 8 (brain)
chr1_-_38285033 0.692 NM_002699
POU3F1
POU class 3 homeobox 1
chr16_+_550394 0.681 NM_145270
C16orf11
chromosome 16 open reading frame 11
chr5_+_31229609 0.680 CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr22_+_24895623 0.679 SEZ6L
seizure related 6 homolog (mouse)-like
chr12_+_46133 0.679 NM_001170738
IQSEC3
IQ motif and Sec7 domain 3
chr6_+_45498354 0.676 RUNX2
runt-related transcription factor 2
chr4_-_44145580 0.673 NM_198353
KCTD8
potassium channel tetramerisation domain containing 8
chr3_+_54131731 0.671 NM_018398
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr11_-_88864061 0.671 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr9_-_37024358 0.671 NM_016734
PAX5
paired box 5
chr2_-_166359016 0.668 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr7_-_20791907 0.668


chr9_-_84867862 0.666 NM_152573
RASEF
RAS and EF-hand domain containing
chr11_+_108798047 0.665 NM_207645
C11orf87
chromosome 11 open reading frame 87
chr1_+_154878344 0.662 NM_021948
NM_198427
BCAN

brevican

chr2_+_185171480 0.662 ZNF804A
zinc finger protein 804A
chr3_+_195889845 0.660 FAM43A
family with sequence similarity 43, member A
chr2_-_219558517 0.658 NM_017521
FEV
FEV (ETS oncogene family)
chr7_+_94374862 0.657 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr14_-_91576037 0.656 NM_004239
TRIP11
thyroid hormone receptor interactor 11
chr4_-_139382672 0.653 NM_014331
SLC7A11
solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
chr11_+_56984702 0.652 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr9_-_10602722 0.651 NM_002839
PTPRD
protein tyrosine phosphatase, receptor type, D

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.65 3.79e-21 GO:0022008 neurogenesis
1.50 8.81e-21 GO:0007399 nervous system development
1.66 2.01e-20 GO:0048699 generation of neurons
1.72 2.69e-19 GO:0030182 neuron differentiation
1.33 2.72e-19 GO:0048731 system development
1.38 1.35e-17 GO:0030154 cell differentiation
1.29 5.67e-17 GO:0048856 anatomical structure development
1.37 8.81e-17 GO:0048869 cellular developmental process
1.10 9.50e-17 GO:0009987 cellular process
1.15 2.54e-16 GO:0065007 biological regulation
1.27 2.95e-16 GO:0007275 multicellular organismal development
1.16 4.91e-16 GO:0050794 regulation of cellular process
1.56 1.75e-15 GO:0048468 cell development
1.24 4.79e-15 GO:0032502 developmental process
1.75 1.62e-14 GO:0000904 cell morphogenesis involved in differentiation
1.32 1.87e-14 GO:0048519 negative regulation of biological process
1.41 2.51e-14 GO:0009653 anatomical structure morphogenesis
1.34 2.69e-14 GO:0048523 negative regulation of cellular process
1.15 2.93e-14 GO:0050789 regulation of biological process
1.67 2.73e-13 GO:0048666 neuron development
1.78 8.75e-13 GO:0007409 axonogenesis
1.76 1.52e-12 GO:0048667 cell morphogenesis involved in neuron differentiation
1.70 3.50e-12 GO:0031175 neuron projection development
1.84 1.18e-11 GO:0007411 axon guidance
1.23 2.16e-11 GO:0060255 regulation of macromolecule metabolic process
1.72 2.49e-11 GO:0048812 neuron projection morphogenesis
1.22 3.83e-11 GO:0031323 regulation of cellular metabolic process
1.46 1.67e-10 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.22 1.69e-10 GO:0080090 regulation of primary metabolic process
1.19 2.97e-10 GO:0044260 cellular macromolecule metabolic process
1.59 3.52e-10 GO:0000902 cell morphogenesis
1.63 7.48e-10 GO:0048858 cell projection morphogenesis
1.56 8.35e-10 GO:0032989 cellular component morphogenesis
1.20 1.79e-09 GO:0019222 regulation of metabolic process
1.62 1.89e-09 GO:0032990 cell part morphogenesis
1.30 2.94e-09 GO:0048513 organ development
1.25 4.83e-09 GO:0010468 regulation of gene expression
1.53 8.06e-09 GO:0030030 cell projection organization
1.60 1.00e-08 GO:0007417 central nervous system development
1.25 1.00e-08 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.24 1.11e-08 GO:0009889 regulation of biosynthetic process
1.24 1.61e-08 GO:0048518 positive regulation of biological process
1.25 1.80e-08 GO:0010556 regulation of macromolecule biosynthetic process
1.25 1.96e-08 GO:0048522 positive regulation of cellular process
1.24 2.05e-08 GO:0031326 regulation of cellular biosynthetic process
1.39 3.70e-08 GO:0010646 regulation of cell communication
1.35 5.33e-08 GO:0009893 positive regulation of metabolic process
1.37 9.90e-08 GO:0010604 positive regulation of macromolecule metabolic process
1.25 1.89e-07 GO:0006355 regulation of transcription, DNA-dependent
1.35 2.28e-07 GO:0031325 positive regulation of cellular metabolic process
1.48 2.57e-07 GO:0010628 positive regulation of gene expression
1.57 2.62e-07 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.14 3.07e-07 GO:0032501 multicellular organismal process
1.18 3.76e-07 GO:0023052 signaling
1.15 3.89e-07 GO:0043170 macromolecule metabolic process
1.24 4.55e-07 GO:0051252 regulation of RNA metabolic process
1.27 4.86e-07 GO:0010467 gene expression
1.21 1.65e-06 GO:0051171 regulation of nitrogen compound metabolic process
1.99 1.77e-06 GO:0045165 cell fate commitment
1.47 2.64e-06 GO:0045893 positive regulation of transcription, DNA-dependent
1.45 2.87e-06 GO:0051254 positive regulation of RNA metabolic process
1.39 2.91e-06 GO:0040011 locomotion
1.47 4.08e-06 GO:0009887 organ morphogenesis
1.12 4.48e-06 GO:0044237 cellular metabolic process
1.28 4.97e-06 GO:0023051 regulation of signaling
1.27 5.58e-06 GO:0016070 RNA metabolic process
1.61 6.12e-06 GO:0007420 brain development
1.41 7.22e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49 9.10e-06 GO:0051253 negative regulation of RNA metabolic process
1.21 9.15e-06 GO:0044267 cellular protein metabolic process
1.31 1.03e-05 GO:0051239 regulation of multicellular organismal process
1.20 1.25e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.40 1.25e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.48 1.65e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.45 1.79e-05 GO:0010629 negative regulation of gene expression
1.49 2.24e-05 GO:0006935 chemotaxis
1.49 2.24e-05 GO:0042330 taxis
1.36 2.81e-05 GO:0010605 negative regulation of macromolecule metabolic process
1.39 4.29e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
1.34 4.36e-05 GO:0009892 negative regulation of metabolic process
1.37 4.56e-05 GO:0031328 positive regulation of cellular biosynthetic process
1.33 6.74e-05 GO:0032268 regulation of cellular protein metabolic process
1.43 9.49e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.48 1.11e-04 GO:0019226 transmission of nerve impulse
1.48 1.11e-04 GO:0035637 multicellular organismal signaling
1.19 1.16e-04 GO:0071842 cellular component organization at cellular level
1.35 1.17e-04 GO:0031324 negative regulation of cellular metabolic process
1.50 1.33e-04 GO:0007268 synaptic transmission
1.16 1.40e-04 GO:0016043 cellular component organization
1.35 1.58e-04 GO:0009891 positive regulation of biosynthetic process
1.42 1.64e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.41 1.79e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.18 1.95e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.16 2.28e-04 GO:0071840 cellular component organization or biogenesis
1.39 2.34e-04 GO:0009890 negative regulation of biosynthetic process
1.79 2.36e-04 GO:0030900 forebrain development
1.30 2.54e-04 GO:0051246 regulation of protein metabolic process
1.39 2.65e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.39 3.90e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.48 3.90e-04 GO:0023057 negative regulation of signaling
1.31 4.55e-04 GO:0007154 cell communication
1.48 4.65e-04 GO:0010648 negative regulation of cell communication
1.54 4.97e-04 GO:0007389 pattern specification process
1.48 5.25e-04 GO:0032583 regulation of gene-specific transcription
1.60 6.42e-04 GO:0051960 regulation of nervous system development
1.45 7.05e-04 GO:0072358 cardiovascular system development
1.45 7.05e-04 GO:0072359 circulatory system development
1.33 7.77e-04 GO:0006351 transcription, DNA-dependent
1.35 8.42e-04 GO:0007267 cell-cell signaling
1.15 9.68e-04 GO:0007165 signal transduction
1.30 1.08e-03 GO:0009605 response to external stimulus
1.47 1.52e-03 GO:0009968 negative regulation of signal transduction
1.15 1.55e-03 GO:0051179 localization
1.19 1.58e-03 GO:0065008 regulation of biological quality
1.09 1.62e-03 GO:0008152 metabolic process
1.42 1.66e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.31 1.75e-03 GO:0050793 regulation of developmental process
1.47 2.31e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.37 2.32e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.60 2.53e-03 GO:0050767 regulation of neurogenesis
1.35 3.20e-03 GO:0045595 regulation of cell differentiation
1.21 3.26e-03 GO:0006464 protein modification process
1.22 3.40e-03 GO:0009059 macromolecule biosynthetic process
1.32 3.63e-03 GO:0044093 positive regulation of molecular function
1.13 4.14e-03 GO:0051716 cellular response to stimulus
1.35 4.36e-03 GO:0009790 embryo development
1.09 4.75e-03 GO:0044238 primary metabolic process
1.22 4.86e-03 GO:0034645 cellular macromolecule biosynthetic process
1.23 5.76e-03 GO:0009966 regulation of signal transduction
2.14 5.81e-03 GO:0042472 inner ear morphogenesis
1.73 5.89e-03 GO:0006813 potassium ion transport
1.32 6.45e-03 GO:0031399 regulation of protein modification process
1.64 7.03e-03 GO:0045664 regulation of neuron differentiation
1.51 7.56e-03 GO:0060284 regulation of cell development
1.20 7.62e-03 GO:0007166 cell surface receptor linked signaling pathway
1.32 7.93e-03 GO:2000026 regulation of multicellular organismal development
1.28 8.22e-03 GO:0032774 RNA biosynthetic process
1.30 1.03e-02 GO:0009888 tissue development
1.33 1.17e-02 GO:0019220 regulation of phosphate metabolic process
1.33 1.17e-02 GO:0051174 regulation of phosphorus metabolic process
1.46 1.26e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.15 1.29e-02 GO:0019538 protein metabolic process
1.56 1.88e-02 GO:0048568 embryonic organ development
1.40 2.04e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.27 2.06e-02 GO:0042127 regulation of cell proliferation
1.26 2.34e-02 GO:0042981 regulation of apoptosis
1.15 2.41e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.89 2.48e-02 GO:0048839 inner ear development
1.25 2.58e-02 GO:0010941 regulation of cell death
1.47 3.12e-02 GO:0051098 regulation of binding
1.50 3.35e-02 GO:0061061 muscle structure development
1.61 3.45e-02 GO:0048732 gland development
1.25 3.51e-02 GO:0043067 regulation of programmed cell death
1.41 3.54e-02 GO:0016477 cell migration
1.17 3.67e-02 GO:0090304 nucleic acid metabolic process
1.39 3.76e-02 GO:0051094 positive regulation of developmental process
1.18 4.46e-02 GO:0043412 macromolecule modification
1.72 4.73e-02 GO:0060537 muscle tissue development
1.87 4.76e-02 GO:0021537 telencephalon development
1.50 4.79e-02 GO:0051101 regulation of DNA binding
1.21 4.83e-02 GO:0065009 regulation of molecular function

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 8.14e-16 GO:0044424 intracellular part
1.08 1.10e-14 GO:0005622 intracellular
1.10 4.22e-09 GO:0043231 intracellular membrane-bounded organelle
1.10 4.44e-09 GO:0043227 membrane-bounded organelle
1.08 3.67e-08 GO:0043226 organelle
1.08 3.78e-08 GO:0043229 intracellular organelle
1.14 5.20e-08 GO:0005634 nucleus
1.19 4.23e-07 GO:0043234 protein complex
1.79 5.28e-07 GO:0034702 ion channel complex
1.09 8.18e-07 GO:0005737 cytoplasm
1.97 1.31e-06 GO:0034703 cation channel complex
1.17 2.22e-06 GO:0032991 macromolecular complex
1.54 4.68e-06 GO:0043005 neuron projection
2.12 2.62e-05 GO:0008076 voltage-gated potassium channel complex
2.12 2.62e-05 GO:0034705 potassium channel complex
1.48 9.62e-05 GO:0045202 synapse
1.20 4.75e-04 GO:0031981 nuclear lumen
1.65 7.97e-04 GO:0030425 dendrite
1.33 8.91e-04 GO:0044451 nucleoplasm part
1.18 1.11e-03 GO:0005829 cytosol
1.18 1.67e-03 GO:0044428 nuclear part
1.50 1.87e-03 GO:0044456 synapse part
1.23 2.48e-03 GO:0005654 nucleoplasm
1.16 2.80e-03 GO:0031974 membrane-enclosed lumen
1.16 3.44e-03 GO:0043233 organelle lumen
1.09 5.38e-03 GO:0044446 intracellular organelle part
1.16 5.61e-03 GO:0070013 intracellular organelle lumen
1.09 6.17e-03 GO:0044422 organelle part
1.03 8.12e-03 GO:0044464 cell part
1.03 8.57e-03 GO:0005623 cell
1.28 8.84e-03 GO:0031410 cytoplasmic vesicle
1.08 9.91e-03 GO:0044444 cytoplasmic part
1.28 1.34e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.49 1.50e-02 GO:0005667 transcription factor complex
1.57 1.70e-02 GO:0030424 axon
1.27 2.39e-02 GO:0031988 membrane-bounded vesicle
1.26 3.18e-02 GO:0031982 vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 1.14e-19 GO:0005515 protein binding
1.66 6.68e-17 GO:0043565 sequence-specific DNA binding
1.52 5.73e-16 GO:0030528 transcription regulator activity
1.07 8.08e-12 GO:0005488 binding
1.43 1.23e-10 GO:0001071 nucleic acid binding transcription factor activity
1.43 1.23e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
1.80 5.78e-06 GO:0005244 voltage-gated ion channel activity
1.80 5.78e-06 GO:0022832 voltage-gated channel activity
1.58 4.45e-05 GO:0022836 gated channel activity
1.57 7.13e-05 GO:0016564 transcription repressor activity
1.56 7.56e-05 GO:0016563 transcription activator activity
1.82 2.02e-04 GO:0022843 voltage-gated cation channel activity
1.92 1.33e-03 GO:0005249 voltage-gated potassium channel activity
1.79 2.24e-03 GO:0005267 potassium channel activity
1.14 2.37e-03 GO:0003676 nucleic acid binding
1.95 4.20e-03 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.16 4.55e-03 GO:0003677 DNA binding
1.61 4.70e-03 GO:0010843 promoter binding
1.58 6.67e-03 GO:0000975 regulatory region DNA binding
1.58 6.67e-03 GO:0001067 regulatory region nucleic acid binding
1.58 6.67e-03 GO:0044212 transcription regulatory region DNA binding
1.47 8.91e-03 GO:0008134 transcription factor binding
1.41 9.39e-03 GO:0005216 ion channel activity
1.92 1.13e-02 GO:0019199 transmembrane receptor protein kinase activity
1.85 1.29e-02 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
1.40 1.37e-02 GO:0022838 substrate-specific channel activity
1.39 1.72e-02 GO:0015267 channel activity
1.38 1.98e-02 GO:0022803 passive transmembrane transporter activity
1.37 2.63e-02 GO:0019904 protein domain specific binding
1.15 4.34e-02 GO:0000166 nucleotide binding