Motif ID: MAZ.p2

Z-value: 2.923


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_297253110.146.1e-01Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_103525646 6.492 NM_006119
NM_033163
NM_033164
NM_033165
 FGF8



fibroblast growth factor 8 (androgen-induced)



chr4_-_809879 6.355 NM_006651
 CPLX1
complexin 1
chr19_+_659766 5.566 NM_001040134
NM_002579
 PALM

paralemmin

chr19_-_2672337 4.833 NM_145173
 DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr6_-_94185780 4.553 NM_004440
 EPHA7
EPH receptor A7
chr11_-_118739838 4.478 USP2
ubiquitin specific peptidase 2
chr19_-_55524445 4.137 NM_004977
 KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr5_-_134397740 4.096 NM_002653
 PITX1
paired-like homeodomain 1
chr7_-_158073121 4.069 NM_002847
NM_130842
NM_130843
 PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr4_-_5940893 3.976 CRMP1
collapsin response mediator protein 1
chr16_-_2186465 3.938 NM_020764
 CASKIN1
CASK interacting protein 1
chr1_-_11674264 3.904 NM_001127325
 MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr6_-_33268177 3.869 NM_001163771
NM_080679
NM_080680
NM_080681
 COL11A2



collagen, type XI, alpha 2



chr13_-_113066202 3.757 GRTP1
growth hormone regulated TBC protein 1
chr11_+_56984702 3.563 NM_178570
 RTN4RL2
reticulon 4 receptor-like 2
chr4_-_5945596 3.562 NM_001014809
 CRMP1
collapsin response mediator protein 1
chr19_-_242335 3.543 NM_003712
NM_177526
 PPAP2C

phosphatidic acid phosphatase type 2C

chr7_+_5289079 3.421 NM_001040661
NM_153247
 SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr11_-_118740069 3.350 NM_171997
 USP2
ubiquitin specific peptidase 2
chr15_-_86600658 3.222 NM_001007156
NM_001012338
NM_002530
 NTRK3


neurotrophic tyrosine kinase, receptor, type 3



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 111 entries
enrichment   p-value GO term description
1.99 3.94e-02 GO:0071804 cellular potassium ion transport
1.99 3.94e-02 GO:0071805 potassium ion transmembrane transport
1.68 1.31e-08 GO:0006813 potassium ion transport
1.43 1.88e-02 GO:0030900 forebrain development
1.43 3.77e-02 GO:0048562 embryonic organ morphogenesis
1.39 6.80e-13 GO:0030182 neuron differentiation
1.39 2.11e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.38 6.44e-08 GO:0031175 neuron projection development
1.38 5.60e-07 GO:0048812 neuron projection morphogenesis
1.38 1.65e-06 GO:0007409 axonogenesis
1.38 1.19e-04 GO:0007411 axon guidance
1.36 5.72e-15 GO:0022008 neurogenesis
1.36 7.61e-14 GO:0048699 generation of neurons
1.36 1.62e-08 GO:0048666 neuron development
1.36 2.96e-07 GO:0032990 cell part morphogenesis
1.36 3.13e-07 GO:0000904 cell morphogenesis involved in differentiation
1.36 5.68e-07 GO:0048858 cell projection morphogenesis
1.35 1.12e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.35 1.08e-03 GO:0015672 monovalent inorganic cation transport
1.35 4.35e-02 GO:0048568 embryonic organ development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 34 entries
enrichment   p-value GO term description
1.63 6.50e-04 GO:0008076 voltage-gated potassium channel complex
1.63 6.50e-04 GO:0034705 potassium channel complex
1.48 2.35e-03 GO:0034703 cation channel complex
1.38 2.30e-02 GO:0043025 neuronal cell body
1.37 3.77e-03 GO:0034702 ion channel complex
1.33 3.34e-05 GO:0045202 synapse
1.33 1.54e-03 GO:0044456 synapse part
1.33 9.96e-03 GO:0005667 transcription factor complex
1.32 2.66e-02 GO:0016323 basolateral plasma membrane
1.30 1.42e-06 GO:0030054 cell junction
1.29 1.14e-03 GO:0043005 neuron projection
1.27 4.84e-02 GO:0005578 proteinaceous extracellular matrix
1.15 4.05e-07 GO:0044459 plasma membrane part
1.14 2.48e-05 GO:0005829 cytosol
1.13 5.14e-05 GO:0070013 intracellular organelle lumen
1.13 1.24e-04 GO:0043233 organelle lumen
1.13 4.37e-04 GO:0044428 nuclear part
1.13 9.05e-04 GO:0031981 nuclear lumen
1.12 2.80e-04 GO:0031974 membrane-enclosed lumen
1.10 3.61e-03 GO:0043234 protein complex

Gene overrepresentation in function category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
2.07 3.33e-02 GO:0015079 potassium ion transmembrane transporter activity
1.66 7.81e-07 GO:0005267 potassium channel activity
1.62 4.18e-04 GO:0005249 voltage-gated potassium channel activity
1.59 1.39e-08 GO:0005244 voltage-gated ion channel activity
1.59 1.39e-08 GO:0022832 voltage-gated channel activity
1.59 5.14e-06 GO:0022843 voltage-gated cation channel activity
1.49 2.44e-08 GO:0005261 cation channel activity
1.42 1.11e-06 GO:0022836 gated channel activity
1.41 1.42e-15 GO:0043565 sequence-specific DNA binding
1.39 2.50e-07 GO:0005216 ion channel activity
1.37 4.47e-07 GO:0015267 channel activity
1.37 6.13e-07 GO:0022803 passive transmembrane transporter activity
1.37 9.08e-07 GO:0022838 substrate-specific channel activity
1.34 4.90e-02 GO:0000975 regulatory region DNA binding
1.34 4.90e-02 GO:0001067 regulatory region nucleic acid binding
1.34 4.90e-02 GO:0044212 transcription regulatory region DNA binding
1.31 1.84e-12 GO:0001071 nucleic acid binding transcription factor activity
1.31 1.84e-12 GO:0003700 sequence-specific DNA binding transcription factor activity
1.31 1.31e-04 GO:0019904 protein domain specific binding
1.31 5.35e-03 GO:0016563 transcription activator activity