Motif ID: MSX1,2.p2

Z-value: 0.625


Transcription factors associated with MSX1,2.p2:

Gene SymbolEntrez IDGene Name
MSX1 4487 msh homeobox 1
MSX2 4488 msh homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MSX1chr4_+_49122720.648.0e-03Click!
MSX2chr5_+_1740841370.097.4e-01Click!


Activity profile for motif MSX1,2.p2.

activity profile for motif MSX1,2.p2


Sorted Z-values histogram for motif MSX1,2.p2

Sorted Z-values for motif MSX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MSX1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_151456683 0.729 NM_001195571
 PRR9
proline rich 9
chr1_-_188713324 0.704 NM_199051
 FAM5C
family with sequence similarity 5, member C
chr7_-_96471544 0.599 DLX6-AS1
DLX6 antisense RNA 1 (non-protein coding)
chr11_-_83071084 0.542 NM_001142702
 DLG2
discs, large homolog 2 (Drosophila)
chr6_-_52060327 0.524 NM_138694
NM_170724
 PKHD1

polycystic kidney and hepatic disease 1 (autosomal recessive)

chrX_+_115481774 0.451 NM_007231
 SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr4_-_41579325 0.448


chr17_+_65582981 0.423 NM_018658
NM_170741
 KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr2_-_68952006 0.419 NM_014482
 BMP10
bone morphogenetic protein 10
chr17_-_30909219 0.406 NM_001129820
 SLFN14
schlafen family member 14
chr7_+_94377145 0.392 NM_001166161
NM_001166162
NM_001166163
 PPP1R9A


protein phosphatase 1, regulatory (inhibitor) subunit 9A


chr3_-_127810087 0.386 NM_001039783
 TXNRD3IT1
thioredoxin reductase 3 intronic transcript 1
chr12_+_70119785 0.380 LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr4_-_159311959 0.373 FAM198B
family with sequence similarity 198, member B
chrX_-_11194015 0.373 NM_013423
 ARHGAP6
Rho GTPase activating protein 6
chr9_+_119506428 0.358 TLR4
toll-like receptor 4
chr7_+_80069439 0.354 NM_001001547
 CD36
CD36 molecule (thrombospondin receptor)
chr3_+_129690735 0.345


chr19_-_14030970 0.334 NM_001145028
 PALM3
paralemmin 3
chr4_-_66218777 0.326 EPHA5
EPH receptor A5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.08 3.78e-02 GO:0009605 response to external stimulus
1.88 4.92e-02 GO:0050877 neurological system process
1.87 5.23e-03 GO:0003008 system process
1.49 8.30e-05 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
30.96 1.52e-02 GO:0071437 invadopodium
2.29 1.47e-03 GO:0005624 membrane fraction
2.28 1.14e-03 GO:0005626 insoluble fraction
1.94 1.38e-02 GO:0000267 cell fraction
1.69 1.78e-08 GO:0071944 cell periphery
1.67 6.60e-08 GO:0005886 plasma membrane
1.64 8.33e-03 GO:0044459 plasma membrane part
1.61 3.40e-02 GO:0005576 extracellular region
1.34 2.08e-03 GO:0044425 membrane part
1.28 2.16e-03 GO:0016020 membrane

Nothing significant found in function category.