Motif ID: MYB.p2

Z-value: 1.866


Transcription factors associated with MYB.p2:

Gene SymbolEntrez IDGene Name
MYB 4602 v-myb myeloblastosis viral oncogene homolog (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYBchr6_+_1355442140.562.5e-02Click!


Activity profile for motif MYB.p2.

activity profile for motif MYB.p2


Sorted Z-values histogram for motif MYB.p2

Sorted Z-values for motif MYB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_35347791 2.422 RALGAPA1
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr2_-_176575171 2.343 NM_030650
KIAA1715
KIAA1715
chr16_-_22293097 2.233 NM_001802
CDR2
cerebellar degeneration-related protein 2, 62kDa
chr10_+_32775027 2.076 NM_001026383
NM_145023
CCDC7

coiled-coil domain containing 7

chr3_-_121295202 1.958 GSK3B
glycogen synthase kinase 3 beta
chr9_+_4669557 1.897 NM_017913
CDC37L1
cell division cycle 37 homolog (S. cerevisiae)-like 1
chr2_+_201099093 1.812 NM_001160033
NM_001160046
NM_152524
SGOL2


shugoshin-like 2 (S. pombe)


chr2_-_61098867 1.800 NM_144709
PUS10
pseudouridylate synthase 10
chr2_+_61098200 1.759 NM_002618
PEX13
peroxisomal biogenesis factor 13
chr2_+_61098355 1.501 PEX13
peroxisomal biogenesis factor 13
chr1_-_84928473 1.400 NM_001166295
NM_001166417
NM_001166293
NM_001166294
NM_014021
SSX2IP




synovial sarcoma, X breakpoint 2 interacting protein




chr2_+_85619797 1.384 NM_005911
MAT2A
methionine adenosyltransferase II, alpha
chr14_+_59628381 1.357 NM_022495
C14orf135
chromosome 14 open reading frame 135
chr14_-_22840249 1.320


chr2_-_55500450 1.317 NM_001135597
NM_018084
CCDC88A

coiled-coil domain containing 88A

chr2_-_172675873 1.218 DLX2
distal-less homeobox 2
chr1_+_32251988 1.186 NM_006559
KHDRBS1
KH domain containing, RNA binding, signal transduction associated 1
chr1_+_144188375 1.170 NM_153713
LIX1L
Lix1 homolog (mouse)-like
chr11_+_32808045 1.148 NM_024081
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr14_-_35348086 1.125 NM_014990
NM_194301
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr2_+_85619802 1.123 MAT2A
methionine adenosyltransferase II, alpha
chr16_+_14072380 1.118 NM_014048
MKL2
MKL/myocardin-like 2
chr1_+_153799637 1.118 LOC645676
hypothetical LOC645676
chr2_-_38831901 1.080 NM_001031684
NM_001195446
SRSF7

serine/arginine-rich splicing factor 7

chr13_+_48720047 1.061 NM_001193478
NM_030911
CDADC1

cytidine and dCMP deaminase domain containing 1

chr2_+_233093416 1.057 NM_001195129
LOC646960
trypsin serine protease-like
chr17_-_46553083 1.043 NM_001130528
NM_003971
SPAG9

sperm associated antigen 9

chr2_+_53867571 1.041 NM_001127397
NM_001127398
NM_015701
ERLEC1


endoplasmic reticulum lectin 1


chr1_-_45924770 1.041 NM_021639
GPBP1L1
GC-rich promoter binding protein 1-like 1
chr6_-_119079712 1.029 NM_001042475
NM_206921
C6orf204

chromosome 6 open reading frame 204

chr2_-_69467825 1.006 NM_002056
GFPT1
glutamine--fructose-6-phosphate transaminase 1
chr1_+_109036431 0.984 NM_018061
PRPF38B
PRP38 pre-mRNA processing factor 38 (yeast) domain containing B
chr2_-_667367 0.984 NM_152834
TMEM18
transmembrane protein 18
chr12_-_10766965 0.950 CSDA
cold shock domain protein A
chr2_-_128285136 0.948 WDR33
WD repeat domain 33
chr16_+_22216223 0.943 NM_018119
POLR3E
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr2_+_227898163 0.930 MFF
mitochondrial fission factor
chr10_+_106103503 0.911 NM_001008723
CCDC147
coiled-coil domain containing 147
chr11_+_74137548 0.911 NM_001098638
RNF169
ring finger protein 169
chr15_-_41000100 0.905 NM_173500
TTBK2
tau tubulin kinase 2
chr2_-_9688552 0.898 NM_006826
YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr20_+_56861430 0.897 NM_001077490
NM_080425
GNAS

GNAS complex locus

chr2_+_96790298 0.897 NM_020184
CNNM4
cyclin M4
chr7_+_64136078 0.894 CCT6P3
chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr17_+_38719371 0.891 NM_145041
TMEM106A
FLJ77644
transmembrane protein 106A
hypothetical LOC728772
chr12_-_56200547 0.884 NM_001195053
NM_001195054
NM_001195055
NM_001195056
NM_001195057
NM_004083
DDIT3





DNA-damage-inducible transcript 3





chr16_+_19442679 0.883 NM_001199022
NM_014711
CP110

CP110 protein

chr6_+_52637116 0.879 LOC730101
hypothetical LOC730101
chr20_+_29790564 0.865 NM_012112
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr14_-_22468393 0.863 PRMT5
protein arginine methyltransferase 5
chr20_+_1254033 0.859 LOC100507495
hypothetical LOC100507495
chr2_-_128285214 0.858 NM_001006622
NM_001006623
NM_018383
WDR33


WD repeat domain 33


chr12_+_4253143 0.858 NM_001759
CCND2
cyclin D2
chr20_-_44151971 0.857 NM_020967
NCOA5
nuclear receptor coactivator 5
chr6_+_45497796 0.839 NM_004348
RUNX2
runt-related transcription factor 2
chr2_+_111152272 0.839


chr16_+_24459173 0.836 RBBP6
retinoblastoma binding protein 6
chr10_-_101935777 0.831 NM_001100626
ERLIN1
ER lipid raft associated 1
chr17_-_50854054 0.813 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr7_-_134845363 0.812 NM_001008225
NM_001190847
NM_001190848
NM_001190849
NM_001190850
NM_013316
CNOT4





CCR4-NOT transcription complex, subunit 4





chr7_+_7974941 0.801 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr17_+_44263370 0.796 NM_005831
CALCOCO2
calcium binding and coiled-coil domain 2
chr20_+_33506322 0.794 NM_007186
CEP250
centrosomal protein 250kDa
chr21_-_33935883 0.793 NM_145858
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr15_-_76378957 0.792 NM_025234
WDR61
WD repeat domain 61
chr2_+_208839195 0.792 NM_001178000
NM_015040
NM_152671
PIKFYVE


phosphoinositide kinase, FYVE finger containing


chr14_-_30565275 0.788 NM_001083893
NM_014574
STRN3

striatin, calmodulin binding protein 3

chr20_-_44151952 0.787 NCOA5
nuclear receptor coactivator 5
chr2_-_177838104 0.778 NM_006164
NFE2L2
nuclear factor (erythroid-derived 2)-like 2
chr11_+_34029764 0.776 NM_005898
NM_203364
CAPRIN1

cell cycle associated protein 1

chr2_-_9687817 0.772 YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr2_+_213857347 0.771 NM_001025436
NM_024532
SPAG16

sperm associated antigen 16

chr17_-_8643163 0.761 NM_152599
MFSD6L
major facilitator superfamily domain containing 6-like
chr10_-_21503025 0.752 NM_001173484
NM_213569
NEBL

nebulette

chr4_-_101090454 0.736 H2AFZ
H2A histone family, member Z
chr6_-_134680888 0.729 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr14_+_35365266 0.726 NM_032352
BRMS1L
breast cancer metastasis-suppressor 1-like
chr14_+_38714111 0.721 NM_002687
PNN
pinin, desmosome associated protein
chr18_-_44730706 0.718 SMAD7
SMAD family member 7
chr2_+_208839325 0.716 PIKFYVE
phosphoinositide kinase, FYVE finger containing
chr18_+_12981329 0.709 NM_032142
CEP192
centrosomal protein 192kDa
chr9_+_107360203 0.708 NM_001079802
NM_001198963
NM_006731
FKTN


fukutin


chr20_+_62357490 0.702 NM_001104925
NM_018257
PCMTD2

protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2

chr2_-_20413838 0.697 PUM2
pumilio homolog 2 (Drosophila)
chr2_-_227372574 0.696 IRS1
insulin receptor substrate 1
chr2_+_60836858 0.693 NM_022894
PAPOLG
poly(A) polymerase gamma
chr14_-_22468445 0.692 NM_001039619
NM_006109
PRMT5

protein arginine methyltransferase 5

chr21_-_14677310 0.687 NM_006948
HSPA13
heat shock protein 70kDa family, member 13
chr10_+_116687904 0.685 NM_139169
TRUB1
TruB pseudouridine (psi) synthase homolog 1 (E. coli)
chr3_+_49034494 0.684 NDUFAF3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr15_+_38673734 0.684 NM_144508
NM_170589
CASC5

cancer susceptibility candidate 5

chr4_-_101090431 0.673 H2AFZ
H2A histone family, member Z
chr20_-_54400628 0.662 NM_003600
NM_198433
NM_198434
NM_198435
NM_198436
NM_198437
AURKA





aurora kinase A





chr5_+_52131686 0.662 PELO
pelota homolog (Drosophila)
chr1_+_42920946 0.660 YBX1
Y box binding protein 1
chr17_+_42023353 0.658 NM_006178
NSF
N-ethylmaleimide-sensitive factor
chr11_+_86426518 0.657 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr16_+_29725311 0.656 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr15_-_39195701 0.656 INO80
INO80 homolog (S. cerevisiae)
chr11_-_110888273 0.652 NM_017589
BTG4
B-cell translocation gene 4
chr20_-_44151924 0.646 NCOA5
nuclear receptor coactivator 5
chr14_+_70178126 0.644 NM_015351
TTC9
tetratricopeptide repeat domain 9
chr4_-_174327377 0.644


chr6_+_28335070 0.637 NM_001007531
NKAPL
NFKB activating protein-like
chr2_-_53867488 0.631 NM_016115
NM_145863
ASB3

ankyrin repeat and SOCS box containing 3

chr6_-_26164478 0.631 NM_005319
HIST1H1C
histone cluster 1, H1c
chr8_+_66719441 0.627 NM_001145839
NM_014637
MTFR1

mitochondrial fission regulator 1

chr3_-_48105287 0.627 MAP4
microtubule-associated protein 4
chr17_+_57909979 0.625 NM_001112707
NM_006852
TLK2

tousled-like kinase 2

chr6_+_70633168 0.625 NM_001858
COL19A1
collagen, type XIX, alpha 1
chr17_-_58239382 0.621 NM_152598
MARCH10
membrane-associated ring finger (C3HC4) 10
chr10_+_92970487 0.620 PCGF5
polycomb group ring finger 5
chr19_-_15404495 0.620 WIZ
widely interspaced zinc finger motifs
chr12_+_92295738 0.618 NM_019094
NM_199040
NUDT4

NUDT4P1
nudix (nucleoside diphosphate linked moiety X)-type motif 4

nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1
chr16_+_48616593 0.618 NM_153261
TMEM188
transmembrane protein 188
chr15_-_39195621 0.617 NM_017553
INO80
INO80 homolog (S. cerevisiae)
chr14_+_23771464 0.615 NM_001002000
NM_001002001
GMPR2

guanosine monophosphate reductase 2

chr20_-_49008445 0.613 NM_003859
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr20_-_39379533 0.612 ZHX3
zinc fingers and homeoboxes 3
chr17_-_44794325 0.604 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr10_+_102123589 0.603 NCRNA00263
non-protein coding RNA 263
chr2_+_172658453 0.601 NM_001038493
NM_178120
DLX1

distal-less homeobox 1

chr17_+_18588050 0.601 NM_031456
FBXW10
CDRT1
F-box and WD repeat domain containing 10
CMT1A duplicated region transcript 1
chr6_-_57194977 0.600 NM_016277
RAB23
RAB23, member RAS oncogene family
chr1_-_115039614 0.598 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr14_-_22521544 0.597 NM_032876
JUB
jub, ajuba homolog (Xenopus laevis)
chr14_+_30098079 0.596 NM_017769
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr6_+_89848229 0.595 PNRC1
proline-rich nuclear receptor coactivator 1
chr6_-_13819463 0.593 RANBP9
RAN binding protein 9
chr2_-_111152075 0.593 NM_004336
BUB1
budding uninhibited by benzimidazoles 1 homolog (yeast)
chr3_-_69212192 0.590 NM_003968
NM_198195
UBA3

ubiquitin-like modifier activating enzyme 3

chr17_+_71292437 0.589 UNK
unkempt homolog (Drosophila)
chr12_-_26169074 0.589 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr12_-_121577410 0.589 NM_023012
RSRC2
arginine/serine-rich coiled-coil 2
chr3_+_52419713 0.586 PHF7
PHD finger protein 7
chr10_-_21502993 0.578 NEBL
nebulette
chr1_+_170768914 0.578 NM_016227
C1orf9
chromosome 1 open reading frame 9
chr16_-_15889968 0.578 C16orf63
chromosome 16 open reading frame 63
chr1_-_77920914 0.576 NM_015534
ZZZ3
zinc finger, ZZ-type containing 3
chr16_+_10945815 0.573 NM_015226
CLEC16A
C-type lectin domain family 16, member A
chr11_+_18374388 0.573 NM_001165414
LDHA
lactate dehydrogenase A
chr16_+_29724926 0.572 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr20_+_62266217 0.569 MYT1
myelin transcription factor 1
chr6_+_99979490 0.564


chr17_+_27701251 0.560 NM_001032293
NM_001098507
NM_003457
ZNF207


zinc finger protein 207


chr16_+_31036474 0.558 NM_032188
NM_182958
MYST1

MYST histone acetyltransferase 1

chr2_-_61618165 0.558 XPO1
exportin 1 (CRM1 homolog, yeast)
chr16_-_15889947 0.556 NM_144600
C16orf63
chromosome 16 open reading frame 63
chr10_-_1769669 0.556 NM_018702
ADARB2
adenosine deaminase, RNA-specific, B2
chr2_-_166358792 0.555 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr2_-_174536761 0.549 SP3
Sp3 transcription factor
chr2_+_74629654 0.546 NM_001197260
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr11_+_65021684 0.545 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr4_-_101090505 0.539 NM_002106
H2AFZ
H2A histone family, member Z
chr6_+_167332781 0.536 NM_007045
NM_194429
FGFR1OP

CCR6
FGFR1 oncogene partner

chemokine (C-C motif) receptor 6
chr20_+_62266270 0.536 NM_004535
MYT1
myelin transcription factor 1
chr6_+_14033076 0.534 NM_001165032
NM_152737
RNF182

ring finger protein 182

chr2_-_9688450 0.532 YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr14_+_23771942 0.528 NM_001002002
NM_016576
GMPR2

guanosine monophosphate reductase 2

chr8_+_30133354 0.525 NM_006571
DCTN6
dynactin 6
chr6_-_27548438 0.524 NM_007149
ZNF184
zinc finger protein 184
chr14_-_22974707 0.518 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr2_-_174537021 0.517 NM_001017371
SP3
Sp3 transcription factor
chr10_-_104943000 0.517 NM_001134373
NM_012229
NT5C2

5'-nucleotidase, cytosolic II

chr16_-_46976649 0.515 NM_003031
SIAH1
seven in absentia homolog 1 (Drosophila)
chr2_+_73466329 0.514 NM_015120
ALMS1
Alstrom syndrome 1
chr14_-_23771312 0.510 NEDD8
neural precursor cell expressed, developmentally down-regulated 8
chr2_+_160277273 0.510 MARCH7
membrane-associated ring finger (C3HC4) 7
chr5_-_43592847 0.508 NM_006451
NM_182789
PAIP1

poly(A) binding protein interacting protein 1

chr1_+_10995265 0.508 NM_007375
TARDBP
TAR DNA binding protein
chr12_+_65949631 0.505 CAND1
cullin-associated and neddylation-dissociated 1
chr22_+_39583001 0.505 NM_022098
XPNPEP3
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr16_+_83239627 0.505 NM_024731
KLHL36
kelch-like 36 (Drosophila)
chr2_-_68238079 0.498 NM_138458
WDR92
WD repeat domain 92
chr16_+_55777739 0.498 NM_133368
RSPRY1
ring finger and SPRY domain containing 1
chr9_+_2005218 0.497 NM_003070
NM_139045
SMARCA2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr17_-_40122542 0.495 NM_001099225
NM_144609
CCDC43

coiled-coil domain containing 43

chr10_+_92970302 0.492 NM_032373
PCGF5
polycomb group ring finger 5
chr11_+_82545784 0.491 NM_015885
PCF11
PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)
chr15_-_61680003 0.490 LOC100130855
hypothetical LOC100130855
chr10_-_92607397 0.489 HTR7
5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
chr2_+_171381626 0.487 GAD1
glutamate decarboxylase 1 (brain, 67kDa)
chr15_+_38673509 0.483 CASC5
cancer susceptibility candidate 5
chr14_-_23771399 0.479 NEDD8
neural precursor cell expressed, developmentally down-regulated 8
chr1_+_107484151 0.477 NM_001113226
NM_001113228
NM_014917
NTNG1


netrin G1


chr5_+_69356827 0.477 NM_001178087
NM_022978
NM_021967
NM_022968
SERF1B

SERF1A

small EDRK-rich factor 1B (centromeric)

small EDRK-rich factor 1A (telomeric)

chr17_+_11864841 0.476 NM_003010
MAP2K4
mitogen-activated protein kinase kinase 4
chr3_+_198961620 0.467 FYTTD1
forty-two-three domain containing 1
chr1_-_153799186 0.467 ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr4_-_47611255 0.467 NM_152995
NFXL1
nuclear transcription factor, X-box binding-like 1
chr6_+_157140733 0.467 NM_017519
NM_020732
ARID1B

AT rich interactive domain 1B (SWI1-like)

chr10_+_97657711 0.465 NM_001130446
C10orf131
chromosome 10 open reading frame 131
chr8_+_65655367 0.460 NM_152414
BHLHE22
basic helix-loop-helix family, member e22
chr2_-_37752731 0.459 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr14_-_54948290 0.458 NM_014924
ATG14
ATG14 autophagy related 14 homolog (S. cerevisiae)
chr15_-_47700342 0.456 NM_152647
C15orf33
chromosome 15 open reading frame 33
chr16_-_66258072 0.456 NM_032140
C16orf48
chromosome 16 open reading frame 48
chr10_+_103103797 0.454 NM_003939
NM_033637
BTRC

beta-transducin repeat containing

chr5_+_139999182 0.454 NM_018502
TMCO6
transmembrane and coiled-coil domains 6
chr6_+_41148869 0.453 NFYA
nuclear transcription factor Y, alpha

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.39 1.93e-15 GO:0044260 cellular macromolecule metabolic process
1.31 8.19e-12 GO:0043170 macromolecule metabolic process
1.82 1.65e-11 GO:0007049 cell cycle
1.91 9.93e-11 GO:0022402 cell cycle process
2.09 1.60e-10 GO:0000278 mitotic cell cycle
1.49 1.06e-09 GO:0090304 nucleic acid metabolic process
1.55 1.85e-08 GO:0006996 organelle organization
1.40 3.61e-08 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22 4.66e-08 GO:0044237 cellular metabolic process
1.85 1.41e-07 GO:0022403 cell cycle phase
1.21 2.08e-07 GO:0044238 primary metabolic process
1.50 2.11e-07 GO:0016070 RNA metabolic process
2.04 2.53e-07 GO:0006325 chromatin organization
2.17 4.52e-07 GO:0016568 chromatin modification
1.18 3.61e-06 GO:0008152 metabolic process
1.32 4.31e-06 GO:0034641 cellular nitrogen compound metabolic process
3.11 4.81e-06 GO:0000086 G2/M transition of mitotic cell cycle
1.37 6.03e-06 GO:0044267 cellular protein metabolic process
1.35 6.23e-06 GO:0071841 cellular component organization or biogenesis at cellular level
1.35 7.28e-06 GO:0071842 cellular component organization at cellular level
1.31 8.54e-06 GO:0006807 nitrogen compound metabolic process
1.80 1.06e-05 GO:0051276 chromosome organization
1.29 1.19e-05 GO:0071840 cellular component organization or biogenesis
1.29 2.72e-05 GO:0016043 cellular component organization
2.14 3.71e-05 GO:0000087 M phase of mitotic cell cycle
1.39 1.82e-04 GO:0010467 gene expression
2.09 2.01e-04 GO:0000280 nuclear division
2.09 2.01e-04 GO:0007067 mitosis
1.79 2.11e-04 GO:0016071 mRNA metabolic process
2.07 2.29e-04 GO:0051329 interphase of mitotic cell cycle
2.06 2.60e-04 GO:0048285 organelle fission
1.87 2.95e-04 GO:0000279 M phase
2.03 4.28e-04 GO:0051325 interphase
5.94 7.29e-04 GO:0007098 centrosome cycle
1.27 1.88e-03 GO:0019538 protein metabolic process
2.00 2.84e-03 GO:0032446 protein modification by small protein conjugation
1.96 2.99e-03 GO:0008380 RNA splicing
1.35 3.07e-03 GO:0006464 protein modification process
2.01 3.25e-03 GO:0007017 microtubule-based process
1.88 3.36e-03 GO:0051301 cell division
1.64 3.48e-03 GO:0051726 regulation of cell cycle
2.03 4.24e-03 GO:0016567 protein ubiquitination
1.88 5.79e-03 GO:0070647 protein modification by small protein conjugation or removal
1.33 6.44e-03 GO:0043412 macromolecule modification
1.69 6.68e-03 GO:0044265 cellular macromolecule catabolic process
7.98 6.89e-03 GO:0051298 centrosome duplication
1.81 7.13e-03 GO:0006397 mRNA processing
2.84 7.58e-03 GO:0000236 mitotic prometaphase
1.08 9.06e-03 GO:0009987 cellular process
1.51 1.10e-02 GO:0006351 transcription, DNA-dependent
1.93 1.33e-02 GO:0010608 posttranscriptional regulation of gene expression
1.43 1.36e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.34 1.84e-02 GO:0034645 cellular macromolecule biosynthetic process
1.34 1.85e-02 GO:0009059 macromolecule biosynthetic process
2.24 1.98e-02 GO:0000226 microtubule cytoskeleton organization
2.37 4.66e-02 GO:0007050 cell cycle arrest

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.20 6.94e-30 GO:0044424 intracellular part
1.19 1.62e-29 GO:0005622 intracellular
1.35 8.36e-20 GO:0005634 nucleus
1.20 1.87e-19 GO:0043229 intracellular organelle
1.20 4.07e-19 GO:0043226 organelle
1.21 3.52e-17 GO:0043231 intracellular membrane-bounded organelle
1.21 5.32e-17 GO:0043227 membrane-bounded organelle
1.60 4.18e-16 GO:0044428 nuclear part
1.29 7.04e-14 GO:0044446 intracellular organelle part
1.28 3.80e-13 GO:0044422 organelle part
1.56 2.42e-11 GO:0031981 nuclear lumen
1.19 3.62e-11 GO:0005737 cytoplasm
1.91 9.06e-10 GO:0015630 microtubule cytoskeleton
1.62 1.04e-09 GO:0005654 nucleoplasm
1.33 4.89e-09 GO:0032991 macromolecular complex
1.44 8.00e-09 GO:0070013 intracellular organelle lumen
1.42 3.04e-08 GO:0043233 organelle lumen
1.41 4.77e-08 GO:0031974 membrane-enclosed lumen
2.19 9.56e-08 GO:0005815 microtubule organizing center
1.36 1.09e-07 GO:0043228 non-membrane-bounded organelle
1.36 1.09e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.34 1.69e-07 GO:0043234 protein complex
2.37 1.74e-06 GO:0005813 centrosome
1.81 4.92e-06 GO:0005694 chromosome
1.88 8.20e-06 GO:0044427 chromosomal part
1.53 2.53e-05 GO:0044430 cytoskeletal part
1.65 3.42e-05 GO:0044451 nucleoplasm part
2.38 3.45e-05 GO:0005819 spindle
1.35 6.46e-05 GO:0005829 cytosol
2.02 1.05e-04 GO:0005874 microtubule
1.17 1.51e-04 GO:0044444 cytoplasmic part
1.37 1.27e-03 GO:0005856 cytoskeleton
3.06 1.62e-03 GO:0000922 spindle pole
2.65 4.61e-03 GO:0000776 kinetochore
1.92 6.91e-03 GO:0005635 nuclear envelope
4.86 1.35e-02 GO:0080008 CUL4 RING ubiquitin ligase complex
2.15 1.95e-02 GO:0000775 chromosome, centromeric region
2.67 2.40e-02 GO:0000777 condensed chromosome kinetochore

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.24 1.35e-14 GO:0005515 protein binding
1.11 1.14e-09 GO:0005488 binding
1.28 1.79e-05 GO:0003676 nucleic acid binding
1.56 3.25e-04 GO:0003723 RNA binding
1.90 1.78e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.55 1.84e-03 GO:0019899 enzyme binding
1.29 2.23e-03 GO:0000166 nucleotide binding
2.01 2.84e-03 GO:0019787 small conjugating protein ligase activity
2.03 3.29e-03 GO:0004842 ubiquitin-protein ligase activity
1.92 4.06e-03 GO:0016881 acid-amino acid ligase activity
3.27 1.59e-02 GO:0042054 histone methyltransferase activity
1.31 3.26e-02 GO:0030554 adenyl nucleotide binding
2.86 3.34e-02 GO:0008276 protein methyltransferase activity
2.60 3.43e-02 GO:0031625 ubiquitin protein ligase binding
1.30 4.83e-02 GO:0032559 adenyl ribonucleotide binding