Motif ID: MYBL2.p2

Z-value: 1.185


Transcription factors associated with MYBL2.p2:

Gene SymbolEntrez IDGene Name
MYBL2 4605 v-myb myeloblastosis viral oncogene homolog (avian)-like 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYBL2chr20_+_41729161-0.155.7e-01Click!


Activity profile for motif MYBL2.p2.

activity profile for motif MYBL2.p2


Sorted Z-values histogram for motif MYBL2.p2

Sorted Z-values for motif MYBL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYBL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_245646080 2.179 NM_001079821
NM_001127461
NLRP3

NLR family, pyrin domain containing 3

chr5_+_73145098 2.158 RGNEF
190 kDa guanine nucleotide exchange factor
chr1_+_557269 1.659


chr11_+_20005704 1.618 NAV2
neuron navigator 2
chr1_+_20269239 1.564 NM_000929
PLA2G5
phospholipase A2, group V
chr1_+_556968 1.552


chr1_+_208472817 1.487 NM_019605
SERTAD4
SERTA domain containing 4
chr11_-_10487212 1.311 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr1_+_165330710 1.226 NM_001080426
DUSP27
dual specificity phosphatase 27 (putative)
chr21_+_36429079 1.186 NM_001236
CBR3
carbonyl reductase 3
chr2_+_64540843 1.160 HSPC159
galectin-related protein
chr3_+_100840129 1.124 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr5_-_79982584 1.099 NM_001190470
MTRNR2L2
MT-RNR2-like 2
chr1_-_24307514 1.076 MYOM3
myomesin family, member 3
chr3_+_3056307 1.075 NM_175612
CNTN4
contactin 4
chr1_+_559618 1.070


chr5_-_37220702 1.058 C5orf42
chromosome 5 open reading frame 42
chr7_+_133884388 1.036 NM_001080538
AKR1B15
aldo-keto reductase family 1, member B15
chr6_-_108252200 1.031 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr12_+_55201854 1.014 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr12_-_26169074 1.005 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr3_+_158637273 0.965 NM_002852
PTX3
pentraxin 3, long
chrX_-_10548458 0.963 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr11_-_85107569 0.953 NM_206929
SYTL2
synaptotagmin-like 2
chr10_-_28611020 0.941 NM_173496
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr11_-_85108030 0.936 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr1_+_8928508 0.929 NM_001215
CA6
carbonic anhydrase VI
chr4_+_120276386 0.881 NM_016599
MYOZ2
myozenin 2
chr6_-_21631992 0.862


chr1_-_20682541 0.859


chr15_+_78520634 0.854 ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr7_+_28497272 0.832 CREB5
cAMP responsive element binding protein 5
chr7_+_116182676 0.810


chr18_+_20294590 0.809 NM_001143828
NM_001160166
NM_021624
HRH4


histamine receptor H4


chr2_+_37425240 0.808 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr6_+_29534109 0.784 NM_030883
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr1_+_146843980 0.773 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chr7_+_150013716 0.751 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr7_+_29569913 0.747 NM_175887
PRR15
proline rich 15
chr6_-_169392771 0.744


chr11_-_124311106 0.738 HEPACAM
hepatic and glial cell adhesion molecule
chr7_+_129771865 0.735 NM_001127441
NM_001127442
NM_080385
CPA5


carboxypeptidase A5


chr12_+_32578513 0.732 FGD4
FYVE, RhoGEF and PH domain containing 4
chr7_-_111216180 0.727 DOCK4
dedicator of cytokinesis 4
chr3_-_188935363 0.713 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr16_-_71639670 0.706 NM_006885
ZFHX3
zinc finger homeobox 3
chr3_+_187840842 0.688 NM_014375
FETUB
fetuin B
chr4_+_3341521 0.685 NM_198227
RGS12
regulator of G-protein signaling 12
chr2_+_182558795 0.685 NM_001080545
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr17_-_46479127 0.684 SPAG9
sperm associated antigen 9
chr11_+_33520348 0.683 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr8_-_95343696 0.679 GEM
GTP binding protein overexpressed in skeletal muscle
chr9_+_71848316 0.674 NM_153267
MAMDC2
MAM domain containing 2
chr5_+_36642424 0.668 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_+_105602606 0.668 NM_032491
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr7_-_93027057 0.665 NM_001164738
CALCR
calcitonin receptor
chr4_+_14950657 0.662 NM_001135170
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr6_+_36773605 0.662 RAB44
RAB44, member RAS oncogene family
chr4_+_77575276 0.661 NM_020859
SHROOM3
shroom family member 3
chr17_-_61655915 0.650 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr1_+_559129 0.649


chr15_+_55298908 0.648 NM_207040
TCF12
transcription factor 12
chr11_+_110890719 0.646 NM_001100388
NM_207430
C11orf88

chromosome 11 open reading frame 88

chr9_+_124463665 0.645 NM_001005236
OR1L1
olfactory receptor, family 1, subfamily L, member 1
chr9_-_14076901 0.630 NFIB
nuclear factor I/B
chr8_-_10550026 0.630 NM_178857
RP1L1
retinitis pigmentosa 1-like 1
chr1_+_159943385 0.627 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr18_+_8708448 0.620


chr1_+_199426575 0.616 NM_001164586
IGFN1
immunoglobulin-like and fibronectin type III domain containing 1
chr1_-_120189301 0.611 NM_001047980
NBPF7
neuroblastoma breakpoint family, member 7
chr5_+_36644187 0.606 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrX_+_135106578 0.603 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr16_-_21919928 0.603 NM_173806
PDZD9
PDZ domain containing 9
chr11_-_85103438 0.598 NM_032379
SYTL2
synaptotagmin-like 2
chr6_+_152053323 0.597 NM_001122742
ESR1
estrogen receptor 1
chr5_-_54317102 0.589 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr16_+_21623784 0.588 NM_170664
OTOA
otoancorin
chr7_+_104539548 0.583 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr5_+_67558217 0.575 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr19_+_11267823 0.554 NM_012466
TSPAN16
tetraspanin 16
chr11_-_35503720 0.542 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr15_-_23201740 0.541 NM_130838
UBE3A
ubiquitin protein ligase E3A
chr21_+_29439768 0.540 C21orf7
chromosome 21 open reading frame 7
chr12_-_14858358 0.533 NM_001013698
C12orf69
chromosome 12 open reading frame 69
chr8_-_95343716 0.530 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr17_-_45617899 0.515 COL1A1
collagen, type I, alpha 1
chr3_+_115099007 0.513 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr12_+_7039453 0.510


chr17_-_45619038 0.509 COL1A1
collagen, type I, alpha 1
chr10_-_98021144 0.508 NM_001114094
NM_013314
BLNK

B-cell linker

chr3_+_160964574 0.494 SCHIP1
schwannomin interacting protein 1
chr12_+_100512877 0.491 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chr17_-_36376663 0.488 NM_213656
KRT39
keratin 39
chr10_-_105835525 0.485 COL17A1
collagen, type XVII, alpha 1
chr1_-_9052170 0.485 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr1_-_143786993 0.481 NM_022359
PDE4DIP
phosphodiesterase 4D interacting protein
chr4_+_37638450 0.480 NM_006607
PTTG2
pituitary tumor-transforming 2
chr5_-_39460787 0.472 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr6_+_148705646 0.471 SASH1
SAM and SH3 domain containing 1
chr6_+_148705421 0.469 NM_015278
SASH1
SAM and SH3 domain containing 1
chr16_+_56230707 0.467 NM_001145774
GPR56
G protein-coupled receptor 56
chr6_+_151602787 0.463 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr3_-_3127057 0.458 NM_000564
NM_175724
NM_175725
NM_175726
NM_175727
NM_175728
IL5RA





interleukin 5 receptor, alpha





chr7_+_139175420 0.458 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr10_-_21847126 0.457


chr10_-_105835609 0.457 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr2_+_135312655 0.456 NM_138326
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr4_-_77147625 0.455 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr16_+_14187965 0.449 MKL2
MKL/myocardin-like 2
chr6_+_155579788 0.445 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr2_+_151922350 0.444 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr2_+_84597087 0.443 NM_001370
DNAH6
dynein, axonemal, heavy chain 6
chrX_-_19598912 0.442 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr18_-_72820939 0.438 MBP
myelin basic protein
chr5_-_39461054 0.435 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chrX_-_128616594 0.433 NM_017413
APLN
apelin
chr1_+_44357108 0.432 NM_173484
KLF17
Kruppel-like factor 17
chr6_+_18495559 0.429 NM_182757
RNF144B
ring finger protein 144B
chr7_+_93388951 0.427 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr16_+_80086454 0.422 NM_030629
CMIP
c-Maf-inducing protein
chr4_-_39655944 0.411 NM_001100399
NM_001100400
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr6_+_41118214 0.406 NM_001010873
NM_001159726
TSPO2

translocator protein 2

chr6_+_167456230 0.405 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr1_-_9052207 0.403 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr12_-_51132129 0.397 NM_005555
KRT6B
keratin 6B
chr11_+_6762823 0.395 NM_001004489
OR2AG1
olfactory receptor, family 2, subfamily AG, member 1
chr11_+_5925152 0.393 NM_001003443
OR56A3
olfactory receptor, family 56, subfamily A, member 3
chr1_+_242283129 0.392 NM_006352
ZNF238
zinc finger protein 238
chr9_-_73865318 0.390 NM_001128618
C9orf57
chromosome 9 open reading frame 57
chr3_+_16949585 0.388 NM_015184
PLCL2
phospholipase C-like 2
chr4_-_47678187 0.387 NM_001142564
CNGA1
cyclic nucleotide gated channel alpha 1
chr19_+_16691786 0.386 NM_001007525
NWD1
NACHT and WD repeat domain containing 1
chr7_-_138014329 0.385 NM_001139456
SVOPL
SVOP-like
chr11_-_124311512 0.384 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr1_+_143326315 0.381 NM_001037675
NBPF10
NBPF9
NBPF8
neuroblastoma breakpoint family, member 10
neuroblastoma breakpoint family, member 9
neuroblastoma breakpoint family, member 8
chr16_+_24475129 0.378 RBBP6
retinoblastoma binding protein 6
chr5_-_39460687 0.378 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr1_+_171871283 0.372 NM_001195190
LOC730159
hypothetical protein LOC730159
chr11_+_60858611 0.371 DAK
dihydroxyacetone kinase 2 homolog (S. cerevisiae)
chr7_+_65057942 0.369 VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr11_+_32994303 0.368 NM_139160
DEPDC7
DEP domain containing 7
chr2_-_227952249 0.366 NM_024795
TM4SF20
transmembrane 4 L six family member 20
chr1_-_201586910 0.365 NM_002023
FMOD
fibromodulin
chrX_+_153952868 0.364 NM_001018055
NM_024332
BRCC3

BRCA1/BRCA2-containing complex, subunit 3

chr1_+_156590109 0.362 NM_001042583
NM_001042584
NM_001042585
NM_001042586
NM_001042587
NM_001185107
NM_001185108
NM_001185110
NM_001185112
NM_001185113
NM_001185114
NM_001185115
NM_030893
CD1E












CD1e molecule












chr9_+_96806235 0.359 C9orf3
chromosome 9 open reading frame 3
chr7_-_98983924 0.358 FAM200A
family with sequence similarity 200, member A
chr11_-_101906640 0.355 NM_002423
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr1_-_150398327 0.354 NM_001122965
RPTN
repetin
chr17_-_36594652 0.353 NM_033060
KRTAP4-1
keratin associated protein 4-1
chr16_-_70168449 0.351 NM_000353
TAT
tyrosine aminotransferase
chr1_+_216585298 0.351 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr2_-_134042500 0.351 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr2_-_101134146 0.350 NM_001102426
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr17_-_45582872 0.349 NM_032595
PPP1R9B
protein phosphatase 1, regulatory (inhibitor) subunit 9B
chr1_+_17448179 0.346 NM_016233
PADI3
peptidyl arginine deiminase, type III
chr1_-_191422346 0.345 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr1_+_18680010 0.338 NM_152375
KLHDC7A
kelch domain containing 7A
chr5_-_16561936 0.337 NM_019000
FAM134B
family with sequence similarity 134, member B
chr1_-_42156913 0.336


chr1_-_201586872 0.335


chr6_+_29249289 0.335 NM_030905
OR2J2
olfactory receptor, family 2, subfamily J, member 2
chr11_-_67207112 0.334 RPL37
ribosomal protein L37
chr17_-_36587965 0.334 NM_033062
KRTAP4-2
keratin associated protein 4-2
chr11_-_36576352 0.332 NM_000536
RAG2
recombination activating gene 2
chr17_-_68100537 0.331 LOC100499467
hypothetical LOC100499467
chr1_+_24518398 0.329 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr1_-_42157077 0.326 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr12_-_55637648 0.320 NM_003708
RDH16
retinol dehydrogenase 16 (all-trans)
chr6_-_136888771 0.320 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr16_-_20271530 0.318 NM_001008389
NM_003361
UMOD

uromodulin

chr6_-_32265489 0.317 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr16_+_22011362 0.316 NM_173615
VWA3A
von Willebrand factor A domain containing 3A
chr10_-_95231933 0.316 NM_013451
NM_133337
MYOF

myoferlin

chr3_+_45902999 0.315 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr3_+_33293915 0.314 NM_012157
NM_001171713
FBXL2

F-box and leucine-rich repeat protein 2

chr6_-_33016561 0.314 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr6_-_36412562 0.312 NM_001010903
C6orf222
chromosome 6 open reading frame 222
chr11_+_5862076 0.311 NM_001005165
OR52E4
olfactory receptor, family 52, subfamily E, member 4
chr1_-_116112921 0.305 NM_001232
CASQ2
calsequestrin 2 (cardiac muscle)
chr21_-_33107813 0.304 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr2_+_101874809 0.302 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr1_-_42156957 0.301 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chrX_-_19898302 0.301 NM_198279
CXorf23
chromosome X open reading frame 23
chr5_+_55098469 0.301 NM_001166534
DDX4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr3_-_113841448 0.300 CCDC80
coiled-coil domain containing 80
chr3_+_14691609 0.298 NM_001184957
NM_001184958
NM_032137
C3orf20


chromosome 3 open reading frame 20


chr7_+_142053693 0.293 NM_001190487
MTRNR2L6
MT-RNR2-like 6
chr21_-_29179482 0.293 NM_013240
NM_182749
N6AMT1

N-6 adenine-specific DNA methyltransferase 1 (putative)

chr4_-_39655554 0.293 PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr16_+_2746363 0.289


chr4_+_187227302 0.287 NM_003265
TLR3
toll-like receptor 3
chr12_-_10142779 0.286 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chr2_-_198248828 0.285 NM_144629
RFTN2
raftlin family member 2
chr3_+_189425886 0.281 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_-_9052253 0.280 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr15_-_74963246 0.278 NM_020843
SCAPER
S-phase cyclin A-associated protein in the ER
chr6_+_35373632 0.277 DEF6
differentially expressed in FDCP 6 homolog (mouse)
chr6_-_24491498 0.276 NM_001195610
DCDC2
doublecortin domain containing 2
chr1_-_21373816 0.276 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
3.44 2.56e-03 GO:0030016 myofibril
3.24 5.65e-03 GO:0043292 contractile fiber
3.35 2.08e-02 GO:0030017 sarcomere
3.11 2.75e-02 GO:0044449 contractile fiber part

Nothing significant found in function category.