Motif ID: MYFfamily.p2

Z-value: 2.794


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYF6chr12_+_796255380.741.1e-03Click!
MYF5chr12_+_796348200.712.2e-03Click!
MYOD1chr11_+_176976850.514.6e-02Click!
MYOGchr1_-_2013217110.077.9e-01Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_34948758 6.626 NM_005584
MAB21L1
mab-21-like 1 (C. elegans)
chr5_+_113725914 6.221 NM_021614
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr5_+_113726203 5.945 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr13_-_71338558 5.287 DACH1
dachshund homolog 1 (Drosophila)
chr13_+_34948885 5.194 NBEA
neurobeachin
chr8_+_56177567 4.970 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr2_-_230287442 4.879 NM_139072
DNER
delta/notch-like EGF repeat containing
chr6_+_99389318 4.599 POU3F2
POU class 3 homeobox 2
chr13_-_71338144 4.547 DACH1
dachshund homolog 1 (Drosophila)
chr6_+_107917965 4.372 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr5_-_59225377 4.171 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_130807865 3.717 NM_015103
PLXND1
plexin D1
chr22_-_19122047 3.205 SCARF2
scavenger receptor class F, member 2
chr8_+_31616809 3.094 NM_013962
NRG1
neuregulin 1
chr22_+_28206180 3.045 NM_021076
NEFH
neurofilament, heavy polypeptide
chr12_+_101876151 3.016 ASCL1
achaete-scute complex homolog 1 (Drosophila)
chr2_+_104838177 2.884 NM_006236
POU3F3
POU class 3 homeobox 3
chr8_-_23768242 2.844 NM_003155
STC1
stanniocalcin 1
chrX_-_92815222 2.729 NM_004538
NAP1L3
nucleosome assembly protein 1-like 3
chr8_+_65656164 2.719 BHLHE22
basic helix-loop-helix family, member e22
chrX_-_99551926 2.618 NM_001105243
NM_001184880
NM_020766
PCDH19


protocadherin 19


chr17_+_14145051 2.481 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chrX_-_74062005 2.439 NM_001008537
KIAA2022
KIAA2022
chr8_+_1937711 2.437 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr5_-_178705036 2.410 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr4_+_61749540 2.406 LPHN3
latrophilin 3
chrX_-_107866262 2.388 NM_003604
IRS4
insulin receptor substrate 4
chr3_-_62835601 2.298


chrX_-_30237403 2.262 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr9_-_139183675 2.260


chr5_-_146238336 2.248 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr6_+_45498354 2.235 RUNX2
runt-related transcription factor 2
chr19_-_15204194 2.227 NM_024794
EPHX3
epoxide hydrolase 3
chr1_+_219119623 2.224 HLX
H2.0-like homeobox
chr18_-_24010944 2.215 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr10_-_132999798 2.205 TCERG1L
transcription elongation regulator 1-like
chr8_+_37773991 2.195 GPR124
G protein-coupled receptor 124
chr17_-_4636248 2.191 NM_001144939
NM_001144940
NM_001144941
NM_182566
VMO1



vitelline membrane outer layer 1 homolog (chicken)



chr7_-_137182125 2.159 NM_004717
DGKI
diacylglycerol kinase, iota
chr15_+_90738108 2.125 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr6_+_5030718 2.120 NM_001145115
PPP1R3G
protein phosphatase 1, regulatory (inhibitor) subunit 3G
chr2_-_27384617 2.091 NM_003353
UCN
urocortin
chr3_+_161426322 2.042 LOC401097
hypothetical protein LOC401097
chr19_+_1236766 2.031 NM_001405
EFNA2
ephrin-A2
chr10_-_132999973 2.027 NM_174937
TCERG1L
transcription elongation regulator 1-like
chr18_-_21185968 2.025 ZNF521
zinc finger protein 521
chr11_-_617172 1.982 NM_021920
SCT
secretin
chr8_-_140784416 1.968 NM_016601
KCNK9
potassium channel, subfamily K, member 9
chr5_+_137829077 1.925 NM_001964
EGR1
early growth response 1
chr4_-_155631861 1.920 DCHS2
dachsous 2 (Drosophila)
chr16_+_85101734 1.885 FOXF1
forkhead box F1
chr14_+_28306633 1.876 FOXG1
forkhead box G1
chr16_+_85101605 1.870 NM_001451
FOXF1
forkhead box F1
chrX_-_110400406 1.855 NM_014289
CAPN6
calpain 6
chr4_+_172971149 1.836 NM_001034845
GALNTL6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr8_-_133562185 1.833 NM_004519
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr11_-_129803712 1.820 NM_007037
ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr15_-_53822468 1.801 NM_173814
PRTG
protogenin
chr1_-_29321599 1.798 NM_001171868
TMEM200B
transmembrane protein 200B
chr13_-_78075683 1.798 NM_006237
POU4F1
POU class 4 homeobox 1
chrX_-_24941098 1.769 ARX
aristaless related homeobox
chr3_+_3816079 1.733 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr2_+_114916368 1.720 NM_020868
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr8_-_133561933 1.719 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr12_+_6807831 1.715 NM_014262
LEPREL2
leprecan-like 2
chr4_+_147779492 1.705 NM_004575
POU4F2
POU class 4 homeobox 2
chr10_-_73518315 1.701 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr5_+_126654354 1.697 NM_032446
MEGF10
multiple EGF-like-domains 10
chr2_-_192767844 1.669 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr3_+_142252890 1.667 SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr3_+_26639300 1.654 NM_052953
LRRC3B
leucine rich repeat containing 3B
chr4_+_134292630 1.645 PCDH10
protocadherin 10
chr2_-_39040981 1.643 LOC375196
hypothetical LOC375196
chrX_-_110400321 1.640 CAPN6
calpain 6
chr5_-_178704934 1.634 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr5_+_92946348 1.623 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr7_+_137182230 1.617


chr8_+_85258056 1.607 NM_173848
RALYL
RALY RNA binding protein-like
chr15_-_50869379 1.604 NM_004498
ONECUT1
one cut homeobox 1
chr19_-_13478037 1.588 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr8_+_37773915 1.586 GPR124
G protein-coupled receptor 124
chr1_+_100777044 1.571 GPR88
G protein-coupled receptor 88
chr6_+_129245978 1.550 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chr5_-_147142457 1.537 JAKMIP2
janus kinase and microtubule interacting protein 2
chr11_-_129803515 1.534 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr5_+_170779264 1.531 NM_003862
FGF18
fibroblast growth factor 18
chr4_-_168392307 1.528 NM_001040159
NM_016950
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr3_+_141136896 1.527 CLSTN2
calsyntenin 2
chr8_+_85258007 1.508 NM_001100392
NM_001100393
RALYL

RALY RNA binding protein-like

chr3_+_161425946 1.508 NM_001168214
LOC401097
hypothetical protein LOC401097
chr12_+_6808025 1.498 LEPREL2
leprecan-like 2
chr14_+_58174489 1.486 NM_001079520
NM_016651
DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

chr19_+_18584666 1.482 NM_012109
TMEM59L
transmembrane protein 59-like
chr6_+_45498262 1.481 RUNX2
runt-related transcription factor 2
chr12_+_130878870 1.476 NM_016155
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr4_-_13155135 1.453 NM_001189
NKX3-2
NK3 homeobox 2
chr11_+_627268 1.446 NM_000797
DRD4
dopamine receptor D4
chr9_-_119217147 1.442 ASTN2
astrotactin 2
chr4_-_168392266 1.432 SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr10_+_83625049 1.431 NM_001010848
NM_001165972
NRG3

neuregulin 3

chrX_+_53095230 1.426 NM_018969
GPR173
G protein-coupled receptor 173
chr3_-_144164867 1.426 NM_198504
PAQR9
progestin and adipoQ receptor family member IX
chr15_-_39593285 1.426 NM_001135685
NM_002344
NM_206961
LTK


leukocyte receptor tyrosine kinase


chr7_+_153380673 1.419 NM_130797
DPP6
dipeptidyl-peptidase 6
chr15_-_63457378 1.419 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr7_-_72822471 1.418 NM_001306
CLDN3
claudin 3
chr4_-_142273881 1.410 NM_020724
RNF150
ring finger protein 150
chrX_+_12066505 1.385 NM_014728
FRMPD4
FERM and PDZ domain containing 4
chr10_-_73518269 1.384 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr1_-_11841476 1.384 NM_002521
NPPB
natriuretic peptide B
chr11_-_2113297 1.378 IGF2
insulin-like growth factor 2 (somatomedin A)
chr10_+_23521464 1.376 NM_178161
PTF1A
pancreas specific transcription factor, 1a
chr5_+_115326035 1.366 NM_173800
AQPEP
laeverin
chr6_+_43151922 1.365 NM_002821
NM_152880
NM_152881
NM_152882
PTK7



PTK7 protein tyrosine kinase 7



chr10_+_25504295 1.355 NM_020752
GPR158
G protein-coupled receptor 158
chr9_-_103540038 1.352 GRIN3A
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
chr10_+_115793795 1.346 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr3_+_112273464 1.333 NM_015480
PVRL3
poliovirus receptor-related 3
chr13_+_34948977 1.333 NBEA
neurobeachin
chr11_+_14621972 1.332 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr16_-_47872880 1.326


chr8_+_99508425 1.321 NM_020697
KCNS2
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr22_-_19122107 1.315 NM_153334
NM_182895
SCARF2

scavenger receptor class F, member 2

chr16_+_2009741 1.300 NPW
neuropeptide W
chr11_-_132907499 1.296 NM_001012393
OPCML
opioid binding protein/cell adhesion molecule-like
chr3_+_195889845 1.285 FAM43A
family with sequence similarity 43, member A
chr22_+_19699441 1.280 NM_001159554
NM_005446
P2RX6

purinergic receptor P2X, ligand-gated ion channel, 6

chr1_+_211190631 1.277 VASH2
vasohibin 2
chr9_-_139184247 1.272 NM_001013653
LRRC26
leucine rich repeat containing 26
chr6_+_72653126 1.235 RIMS1
regulating synaptic membrane exocytosis 1
chr10_-_73518284 1.228 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr3_+_112273352 1.226 PVRL3
poliovirus receptor-related 3
chrX_-_53367246 1.224 NM_001111125
IQSEC2
IQ motif and Sec7 domain 2
chr4_+_15313850 1.219 BST1
bone marrow stromal cell antigen 1
chr6_-_33268177 1.214 NM_001163771
NM_080679
NM_080680
NM_080681
COL11A2



collagen, type XI, alpha 2



chr17_-_15104768 1.212 NM_153322
PMP22
peripheral myelin protein 22
chr10_-_118022965 1.195 NM_005264
GFRA1
GDNF family receptor alpha 1
chr10_+_52504239 1.176 NM_006258
PRKG1
protein kinase, cGMP-dependent, type I
chr5_-_147142249 1.176 JAKMIP2
janus kinase and microtubule interacting protein 2
chr16_-_2186465 1.175 NM_020764
CASKIN1
CASK interacting protein 1
chr8_+_143542378 1.175 NM_001702
BAI1
brain-specific angiogenesis inhibitor 1
chr12_+_93066370 1.174 NM_005761
PLXNC1
plexin C1
chr7_+_98084531 1.171 NM_002523
NPTX2
neuronal pentraxin II
chr20_-_30534848 1.168 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr8_+_106400322 1.167 NM_012082
ZFPM2
zinc finger protein, multitype 2
chrX_+_149280486 1.167 MAMLD1
mastermind-like domain containing 1
chr3_-_124650081 1.158 NM_183357
ADCY5
adenylate cyclase 5
chr5_+_75414994 1.153 NM_014979
SV2C
synaptic vesicle glycoprotein 2C
chr16_+_55180767 1.152 NM_005954
MT3
metallothionein 3
chr10_-_30356344 1.151 KIAA1462
KIAA1462
chr8_-_121893468 1.151 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr12_+_79634820 1.150 NM_005593
MYF5
myogenic factor 5
chr18_-_21186107 1.149 NM_015461
ZNF521
zinc finger protein 521
chr4_-_168392151 1.147 SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr8_+_37773564 1.144 GPR124
G protein-coupled receptor 124
chr9_-_38414422 1.137 NM_001007563
IGFBPL1
insulin-like growth factor binding protein-like 1
chr9_+_86474500 1.125 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr19_+_47509274 1.122 NM_173633
TMEM145
transmembrane protein 145
chr1_-_102235377 1.118 NM_058170
OLFM3
olfactomedin 3
chrX_+_117992623 1.104 NM_001031855
NM_024778
LONRF3

LON peptidase N-terminal domain and ring finger 3

chr3_+_141136691 1.103 NM_022131
CLSTN2
calsyntenin 2
chr1_-_102234959 1.099 OLFM3
olfactomedin 3
chr10_+_42892506 1.097 NM_020630
NM_020975
RET

ret proto-oncogene

chr8_+_37773553 1.096 NM_032777
GPR124
G protein-coupled receptor 124
chr16_-_47872973 1.096 CBLN1
cerebellin 1 precursor
chr15_+_97462675 1.091 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr19_+_56319948 1.089 NM_001198558
NM_014441
SIGLEC9

sialic acid binding Ig-like lectin 9

chr13_-_109236897 1.085 NM_003749
IRS2
insulin receptor substrate 2
chr12_+_70119785 1.084 LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr3_-_18441763 1.078 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr1_-_32002222 1.076 NM_001703
BAI2
brain-specific angiogenesis inhibitor 2
chr1_+_22909916 1.071 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr6_+_150326802 1.069 NM_025218
ULBP1
UL16 binding protein 1
chr8_+_24827181 1.062 NEFM
neurofilament, medium polypeptide
chr9_-_100510657 1.062 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr19_+_55985483 1.061 NM_033068
ACPT
acid phosphatase, testicular
chr21_+_33364420 1.060 OLIG1
oligodendrocyte transcription factor 1
chr9_-_119217128 1.057 NM_014010
ASTN2
astrotactin 2
chr11_+_359723 1.054 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr22_+_22445035 1.051 NM_005940
MMP11
matrix metallopeptidase 11 (stromelysin 3)
chr8_+_24827173 1.049 NM_005382
NEFM
neurofilament, medium polypeptide
chr4_+_7245218 1.047 NM_020777
SORCS2
sortilin-related VPS10 domain containing receptor 2
chr14_-_50631407 1.043 TRIM9
tripartite motif containing 9
chr12_+_50342814 1.041 NM_001177984
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr7_+_96473225 1.027 NM_005222
DLX6
distal-less homeobox 6
chr9_+_86474457 1.023 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr6_+_99389300 1.019 NM_005604
POU3F2
POU class 3 homeobox 2
chr8_+_104452961 1.018 NM_138455
CTHRC1
collagen triple helix repeat containing 1
chr11_-_86343737 1.017 FZD4
frizzled homolog 4 (Drosophila)
chr19_-_51829778 1.012 NM_033258
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr3_+_142253102 1.010 SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr13_+_34414390 1.009 NM_015678
NBEA
neurobeachin
chr9_+_86474553 1.007 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr5_-_139992621 1.006 NM_000591
CD14
CD14 molecule
chr16_-_47873183 1.006 NM_004352
CBLN1
cerebellin 1 precursor
chr5_+_137829065 1.005 EGR1
early growth response 1
chrX_+_23262905 1.004 NM_173495
PTCHD1
patched domain containing 1
chr13_+_30378311 0.993 NM_032849
C13orf33
chromosome 13 open reading frame 33
chr10_+_134893766 0.987 NM_003577
UTF1
undifferentiated embryonic cell transcription factor 1
chr1_+_109594163 0.983 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.35 8.40e-21 GO:0007275 multicellular organismal development
1.40 3.24e-20 GO:0048731 system development
1.57 1.07e-19 GO:0007399 nervous system development
1.32 6.83e-19 GO:0032502 developmental process
1.25 8.88e-19 GO:0032501 multicellular organismal process
1.35 2.07e-18 GO:0048856 anatomical structure development
1.31 2.17e-17 GO:0023052 signaling
1.30 8.69e-14 GO:0007165 signal transduction
1.70 1.08e-13 GO:0007155 cell adhesion
1.70 1.08e-13 GO:0022610 biological adhesion
1.48 1.81e-13 GO:0009653 anatomical structure morphogenesis
1.42 1.40e-12 GO:0007166 cell surface receptor linked signaling pathway
1.62 3.49e-12 GO:0048699 generation of neurons
1.59 8.50e-12 GO:0022008 neurogenesis
1.58 1.80e-11 GO:0048468 cell development
1.67 3.46e-11 GO:0030182 neuron differentiation
1.36 1.84e-10 GO:0030154 cell differentiation
1.37 2.62e-10 GO:0048513 organ development
1.35 3.31e-10 GO:0048869 cellular developmental process
1.70 2.03e-08 GO:0007417 central nervous system development
1.64 4.51e-08 GO:0048666 neuron development
1.61 1.35e-07 GO:0009887 organ morphogenesis
1.15 2.24e-07 GO:0050896 response to stimulus
1.19 9.68e-07 GO:0051716 cellular response to stimulus
1.38 1.71e-06 GO:0051239 regulation of multicellular organismal process
1.63 2.11e-06 GO:0031175 neuron projection development
1.27 4.31e-06 GO:0042221 response to chemical stimulus
1.65 6.75e-06 GO:0048812 neuron projection morphogenesis
1.72 7.09e-06 GO:0007420 brain development
1.65 8.18e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.61 9.31e-06 GO:0000904 cell morphogenesis involved in differentiation
1.12 1.10e-05 GO:0050794 regulation of cellular process
1.48 1.25e-05 GO:0007267 cell-cell signaling
1.76 1.34e-05 GO:0007610 behavior
1.11 2.08e-05 GO:0065007 biological regulation
1.41 2.31e-05 GO:0032879 regulation of localization
1.53 2.84e-05 GO:0000902 cell morphogenesis
1.58 3.30e-05 GO:0048858 cell projection morphogenesis
1.73 4.36e-05 GO:0051046 regulation of secretion
1.50 4.84e-05 GO:0030030 cell projection organization
1.57 6.01e-05 GO:0032990 cell part morphogenesis
1.39 6.37e-05 GO:0007154 cell communication
1.25 7.51e-05 GO:0065008 regulation of biological quality
1.42 8.79e-05 GO:0040011 locomotion
1.49 8.92e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.57 9.01e-05 GO:0019226 transmission of nerve impulse
1.57 9.01e-05 GO:0035637 multicellular organismal signaling
1.50 9.14e-05 GO:0032989 cellular component morphogenesis
1.61 9.26e-05 GO:0007409 axonogenesis
1.11 1.10e-04 GO:0050789 regulation of biological process
1.81 1.78e-04 GO:0030168 platelet activation
1.64 2.14e-04 GO:0048598 embryonic morphogenesis
2.18 2.71e-04 GO:0043583 ear development
1.67 2.74e-04 GO:0044057 regulation of system process
1.57 2.94e-04 GO:0051094 positive regulation of developmental process
1.39 3.10e-04 GO:0050793 regulation of developmental process
1.66 3.29e-04 GO:0007411 axon guidance
1.98 3.62e-04 GO:0048562 embryonic organ morphogenesis
1.58 3.78e-04 GO:0060341 regulation of cellular localization
1.99 6.05e-04 GO:0046883 regulation of hormone secretion
2.26 6.14e-04 GO:0048839 inner ear development
1.66 6.79e-04 GO:0001501 skeletal system development
1.56 6.87e-04 GO:0007268 synaptic transmission
1.77 7.35e-04 GO:0048568 embryonic organ development
1.66 9.82e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.34 1.09e-03 GO:0010646 regulation of cell communication
1.53 1.13e-03 GO:0072358 cardiovascular system development
1.53 1.13e-03 GO:0072359 circulatory system development
1.88 1.24e-03 GO:0030900 forebrain development
2.12 1.30e-03 GO:0050796 regulation of insulin secretion
1.66 1.41e-03 GO:0016337 cell-cell adhesion
2.33 1.62e-03 GO:0042471 ear morphogenesis
1.41 1.73e-03 GO:2000026 regulation of multicellular organismal development
2.06 1.73e-03 GO:0002791 regulation of peptide secretion
2.06 1.73e-03 GO:0090087 regulation of peptide transport
2.90 1.76e-03 GO:0009187 cyclic nucleotide metabolic process
1.41 2.05e-03 GO:0051049 regulation of transport
1.42 2.24e-03 GO:0045595 regulation of cell differentiation
2.43 2.41e-03 GO:0042472 inner ear morphogenesis
2.05 2.72e-03 GO:0090276 regulation of peptide hormone secretion
1.49 2.90e-03 GO:0006935 chemotaxis
1.49 2.90e-03 GO:0042330 taxis
1.61 3.01e-03 GO:0045597 positive regulation of cell differentiation
2.24 4.79e-03 GO:0051048 negative regulation of secretion
1.45 6.83e-03 GO:0007186 G-protein coupled receptor protein signaling pathway
1.93 6.91e-03 GO:0007156 homophilic cell adhesion
1.41 7.13e-03 GO:0009719 response to endogenous stimulus
1.47 7.50e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.33 8.18e-03 GO:0009605 response to external stimulus
1.59 8.37e-03 GO:0051050 positive regulation of transport
1.35 1.03e-02 GO:0009888 tissue development
1.24 1.07e-02 GO:0003008 system process
1.63 1.18e-02 GO:0051960 regulation of nervous system development
1.86 1.61e-02 GO:0045165 cell fate commitment
1.46 1.62e-02 GO:0001775 cell activation
2.01 1.64e-02 GO:0048736 appendage development
2.01 1.64e-02 GO:0060173 limb development
1.65 2.15e-02 GO:0050767 regulation of neurogenesis
1.46 2.16e-02 GO:0050801 ion homeostasis
1.60 2.25e-02 GO:0007423 sensory organ development
1.59 2.58e-02 GO:0001944 vasculature development
1.59 2.58e-02 GO:0040012 regulation of locomotion
1.80 2.72e-02 GO:0006813 potassium ion transport
1.58 2.88e-02 GO:0019932 second-messenger-mediated signaling
1.59 3.01e-02 GO:0051270 regulation of cellular component movement
1.56 3.01e-02 GO:0060284 regulation of cell development
1.92 3.30e-02 GO:0051384 response to glucocorticoid stimulus
3.42 3.53e-02 GO:0046058 cAMP metabolic process
1.23 3.59e-02 GO:0023051 regulation of signaling
1.27 3.70e-02 GO:0010033 response to organic substance
2.21 3.75e-02 GO:0050770 regulation of axonogenesis
1.17 3.85e-02 GO:0048518 positive regulation of biological process
1.98 3.97e-02 GO:0010720 positive regulation of cell development
1.39 4.28e-02 GO:0009725 response to hormone stimulus
1.47 4.48e-02 GO:0006873 cellular ion homeostasis
1.99 4.72e-02 GO:0050954 sensory perception of mechanical stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.40 1.69e-16 GO:0044459 plasma membrane part
1.24 8.40e-13 GO:0005886 plasma membrane
1.23 2.90e-12 GO:0071944 cell periphery
1.47 8.38e-12 GO:0031226 intrinsic to plasma membrane
1.47 1.42e-11 GO:0005887 integral to plasma membrane
1.16 9.28e-11 GO:0044425 membrane part
1.18 1.45e-10 GO:0031224 intrinsic to membrane
1.32 8.33e-10 GO:0005576 extracellular region
1.17 1.39e-08 GO:0016021 integral to membrane
1.77 1.72e-08 GO:0031012 extracellular matrix
1.44 2.39e-08 GO:0044421 extracellular region part
1.12 6.79e-08 GO:0016020 membrane
1.80 1.39e-07 GO:0005578 proteinaceous extracellular matrix
1.76 2.09e-06 GO:0044456 synapse part
1.63 4.36e-06 GO:0045202 synapse
1.48 3.15e-05 GO:0030054 cell junction
1.58 1.09e-04 GO:0009986 cell surface
1.33 1.50e-04 GO:0000267 cell fraction
1.37 2.79e-04 GO:0005626 insoluble fraction
1.37 3.40e-04 GO:0005624 membrane fraction
2.05 3.54e-04 GO:0044420 extracellular matrix part
1.85 1.46e-03 GO:0045211 postsynaptic membrane
1.89 1.88e-03 GO:0043235 receptor complex
1.70 2.00e-03 GO:0034702 ion channel complex
1.32 1.33e-02 GO:0005615 extracellular space

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.26 1.11e-05 GO:0019838 growth factor binding
2.47 1.16e-05 GO:0019199 transmembrane receptor protein kinase activity
1.28 3.74e-05 GO:0004872 receptor activity
1.36 1.05e-04 GO:0005102 receptor binding
2.51 2.65e-04 GO:0004714 transmembrane receptor protein tyrosine kinase activity
1.23 4.05e-04 GO:0004871 signal transducer activity
1.23 4.05e-04 GO:0060089 molecular transducer activity
1.42 5.60e-04 GO:0005509 calcium ion binding
1.53 1.05e-03 GO:0005216 ion channel activity
1.59 1.81e-03 GO:0022836 gated channel activity
1.51 2.39e-03 GO:0022838 substrate-specific channel activity
1.49 3.76e-03 GO:0015267 channel activity
1.49 4.27e-03 GO:0022803 passive transmembrane transporter activity
1.35 5.62e-03 GO:0015075 ion transmembrane transporter activity
1.93 1.02e-02 GO:0008201 heparin binding
1.78 1.54e-02 GO:0005539 glycosaminoglycan binding
1.75 1.63e-02 GO:0001871 pattern binding
1.75 1.63e-02 GO:0030247 polysaccharide binding
1.25 1.83e-02 GO:0004888 transmembrane receptor activity
3.62 2.11e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
1.56 2.39e-02 GO:0005261 cation channel activity
2.04 3.37e-02 GO:0005201 extracellular matrix structural constituent
1.37 3.59e-02 GO:0008324 cation transmembrane transporter activity
1.29 3.84e-02 GO:0022891 substrate-specific transmembrane transporter activity
1.33 4.03e-02 GO:0043565 sequence-specific DNA binding