Motif ID: MYFfamily.p2

Z-value: 2.794


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYF6chr12_+_796255380.741.1e-03Click!
MYF5chr12_+_796348200.712.2e-03Click!
MYOD1chr11_+_176976850.514.6e-02Click!
MYOGchr1_-_2013217110.077.9e-01Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_34948758 6.626 NM_005584
 MAB21L1
mab-21-like 1 (C. elegans)
chr5_+_113725914 6.221 NM_021614
 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr5_+_113726203 5.945 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr13_-_71338558 5.287 DACH1
dachshund homolog 1 (Drosophila)
chr13_+_34948885 5.194 NBEA
neurobeachin
chr8_+_56177567 4.970 NM_052898
 XKR4
XK, Kell blood group complex subunit-related family, member 4
chr2_-_230287442 4.879 NM_139072
 DNER
delta/notch-like EGF repeat containing
chr6_+_99389318 4.599 POU3F2
POU class 3 homeobox 2
chr13_-_71338144 4.547 DACH1
dachshund homolog 1 (Drosophila)
chr6_+_107917965 4.372 NM_018013
 SOBP
sine oculis binding protein homolog (Drosophila)
chr5_-_59225377 4.171 NM_001104631
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_130807865 3.717 NM_015103
 PLXND1
plexin D1
chr22_-_19122047 3.205 SCARF2
scavenger receptor class F, member 2
chr8_+_31616809 3.094 NM_013962
 NRG1
neuregulin 1
chr22_+_28206180 3.045 NM_021076
 NEFH
neurofilament, heavy polypeptide
chr12_+_101876151 3.016 ASCL1
achaete-scute complex homolog 1 (Drosophila)
chr2_+_104838177 2.884 NM_006236
 POU3F3
POU class 3 homeobox 3
chr8_-_23768242 2.844 NM_003155
 STC1
stanniocalcin 1
chrX_-_92815222 2.729 NM_004538
 NAP1L3
nucleosome assembly protein 1-like 3
chr8_+_65656164 2.719 BHLHE22
basic helix-loop-helix family, member e22

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 116 entries
enrichment   p-value GO term description
3.42 3.53e-02 GO:0046058 cAMP metabolic process
2.90 1.76e-03 GO:0009187 cyclic nucleotide metabolic process
2.43 2.41e-03 GO:0042472 inner ear morphogenesis
2.33 1.62e-03 GO:0042471 ear morphogenesis
2.26 6.14e-04 GO:0048839 inner ear development
2.24 4.79e-03 GO:0051048 negative regulation of secretion
2.21 3.75e-02 GO:0050770 regulation of axonogenesis
2.18 2.71e-04 GO:0043583 ear development
2.12 1.30e-03 GO:0050796 regulation of insulin secretion
2.06 1.73e-03 GO:0002791 regulation of peptide secretion
2.06 1.73e-03 GO:0090087 regulation of peptide transport
2.05 2.72e-03 GO:0090276 regulation of peptide hormone secretion
2.01 1.64e-02 GO:0048736 appendage development
2.01 1.64e-02 GO:0060173 limb development
1.99 6.05e-04 GO:0046883 regulation of hormone secretion
1.99 4.72e-02 GO:0050954 sensory perception of mechanical stimulus
1.98 3.62e-04 GO:0048562 embryonic organ morphogenesis
1.98 3.97e-02 GO:0010720 positive regulation of cell development
1.93 6.91e-03 GO:0007156 homophilic cell adhesion
1.92 3.30e-02 GO:0051384 response to glucocorticoid stimulus

Gene overrepresentation in compartment category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
2.05 3.54e-04 GO:0044420 extracellular matrix part
1.89 1.88e-03 GO:0043235 receptor complex
1.85 1.46e-03 GO:0045211 postsynaptic membrane
1.80 1.39e-07 GO:0005578 proteinaceous extracellular matrix
1.77 1.72e-08 GO:0031012 extracellular matrix
1.76 2.09e-06 GO:0044456 synapse part
1.70 2.00e-03 GO:0034702 ion channel complex
1.63 4.36e-06 GO:0045202 synapse
1.58 1.09e-04 GO:0009986 cell surface
1.48 3.15e-05 GO:0030054 cell junction
1.47 8.38e-12 GO:0031226 intrinsic to plasma membrane
1.47 1.42e-11 GO:0005887 integral to plasma membrane
1.44 2.39e-08 GO:0044421 extracellular region part
1.40 1.69e-16 GO:0044459 plasma membrane part
1.37 2.79e-04 GO:0005626 insoluble fraction
1.37 3.40e-04 GO:0005624 membrane fraction
1.33 1.50e-04 GO:0000267 cell fraction
1.32 8.33e-10 GO:0005576 extracellular region
1.32 1.33e-02 GO:0005615 extracellular space
1.24 8.40e-13 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
3.62 2.11e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
2.51 2.65e-04 GO:0004714 transmembrane receptor protein tyrosine kinase activity
2.47 1.16e-05 GO:0019199 transmembrane receptor protein kinase activity
2.26 1.11e-05 GO:0019838 growth factor binding
2.04 3.37e-02 GO:0005201 extracellular matrix structural constituent
1.93 1.02e-02 GO:0008201 heparin binding
1.78 1.54e-02 GO:0005539 glycosaminoglycan binding
1.75 1.63e-02 GO:0001871 pattern binding
1.75 1.63e-02 GO:0030247 polysaccharide binding
1.59 1.81e-03 GO:0022836 gated channel activity
1.56 2.39e-02 GO:0005261 cation channel activity
1.53 1.05e-03 GO:0005216 ion channel activity
1.51 2.39e-03 GO:0022838 substrate-specific channel activity
1.49 3.76e-03 GO:0015267 channel activity
1.49 4.27e-03 GO:0022803 passive transmembrane transporter activity
1.42 5.60e-04 GO:0005509 calcium ion binding
1.37 3.59e-02 GO:0008324 cation transmembrane transporter activity
1.36 1.05e-04 GO:0005102 receptor binding
1.35 5.62e-03 GO:0015075 ion transmembrane transporter activity
1.33 4.03e-02 GO:0043565 sequence-specific DNA binding