Motif ID: MZF1.p2

Z-value: 3.317


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_637759010.185.0e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_159306532 9.549 NM_001163678
NM_003030
NM_006884
SHOX2


short stature homeobox 2


chr7_+_5289079 6.280 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr3_-_159306214 5.636


chr8_+_22513043 4.878 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr1_+_2975590 4.766 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr22_-_28972683 4.676 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr3_+_148610516 4.614 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr2_+_45022540 4.468 NM_005413
SIX3
SIX homeobox 3
chr11_+_17714070 4.456 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr2_-_200030944 4.400 NM_001172509
SATB2
SATB homeobox 2
chr13_+_113574925 4.253 NM_001143945
GAS6
growth arrest-specific 6
chr4_-_1156959 4.142 NM_001128325
SPON2
spondin 2, extracellular matrix protein
chr4_-_1156533 3.996 NM_012445
SPON2
spondin 2, extracellular matrix protein
chr2_+_104837004 3.832


chr4_-_46086528 3.831 NM_000807
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr14_-_60185659 3.774 NM_005982
SIX1
SIX homeobox 1
chr6_-_32227645 3.645 PRRT1
proline-rich transmembrane protein 1
chr4_-_1156378 3.603 SPON2
spondin 2, extracellular matrix protein
chr21_+_42946719 3.594 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr2_+_5750229 3.482 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr3_-_148607096 3.479 NM_032153
ZIC4
Zic family member 4
chr2_-_200030412 3.355 SATB2
SATB homeobox 2
chr4_-_1156458 3.334 SPON2
spondin 2, extracellular matrix protein
chr6_-_32227695 3.328 NM_030651
PRRT1
proline-rich transmembrane protein 1
chr2_+_172658453 3.301 NM_001038493
NM_178120
DLX1

distal-less homeobox 1

chr4_-_1156362 3.291 SPON2
spondin 2, extracellular matrix protein
chr17_-_44047299 3.265 NM_024016
HOXB8
homeobox B8
chr15_-_77170135 3.210 NM_001145648
NM_002891
RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

chr2_+_104838177 2.991 NM_006236
POU3F3
POU class 3 homeobox 3
chr2_+_137239583 2.942 THSD7B
thrombospondin, type I, domain containing 7B
chr9_+_70107602 2.941 NM_199135
FOXD4L3
FOXD4L6
forkhead box D4-like 3
forkhead box D4-like 6
chr15_-_86600658 2.855 NM_001007156
NM_001012338
NM_002530
NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr9_+_125813672 2.819 NM_004789
LHX2
LIM homeobox 2
chr9_+_125813849 2.817 LHX2
LIM homeobox 2
chr4_+_81406765 2.706 NM_004464
NM_033143
FGF5

fibroblast growth factor 5

chr1_-_148155986 2.696 NM_014849
SV2A
synaptic vesicle glycoprotein 2A
chr13_+_99431417 2.675


chr7_-_19123765 2.661 TWIST1
twist homolog 1 (Drosophila)
chr14_-_47213906 2.656 NM_001113498
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr4_-_46086218 2.654 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr11_-_27700180 2.643 NM_170731
BDNF
brain-derived neurotrophic factor
chr6_+_99389300 2.616 NM_005604
POU3F2
POU class 3 homeobox 2
chr21_+_46226072 2.609 NM_001848
COL6A1
collagen, type VI, alpha 1
chr20_-_22512893 2.599 FOXA2
forkhead box A2
chr19_-_13478037 2.582 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr19_-_55914837 2.574


chr15_+_65904994 2.566 NM_001031807
SKOR1
SKI family transcriptional corepressor 1
chr6_+_99389318 2.526 POU3F2
POU class 3 homeobox 2
chr1_-_29321599 2.517 NM_001171868
TMEM200B
transmembrane protein 200B
chr20_-_61755145 2.498 NM_015894
STMN3
stathmin-like 3
chr19_+_60487345 2.488 NM_032430
BRSK1
BR serine/threonine kinase 1
chr5_+_92944680 2.458 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr4_-_109308893 2.457 NM_001130713
NM_001130714
NM_016269
LEF1


lymphoid enhancer-binding factor 1


chr4_-_155632317 2.450 NM_001142552
NM_001142553
DCHS2

dachsous 2 (Drosophila)

chr13_+_87122778 2.415 NM_015567
SLITRK5
SLIT and NTRK-like family, member 5
chr13_-_113066202 2.413 GRTP1
growth hormone regulated TBC protein 1
chr19_+_12805747 2.377 MAST1
microtubule associated serine/threonine kinase 1
chr19_+_54314292 2.368 NM_003660
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr3_+_11009436 2.367 SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr5_-_92942680 2.331 FLJ42709
hypothetical LOC441094
chr13_-_49597776 2.282 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr5_-_88016397 2.275 LOC645323
hypothetical LOC645323
chr6_-_165995510 2.231 NM_001130690
NM_006661
PDE10A

phosphodiesterase 10A

chr3_+_98016114 2.219 NM_001080448
EPHA6
EPH receptor A6
chr2_+_176680251 2.206 NM_021192
HOXD11
homeobox D11
chr1_+_154878344 2.180 NM_021948
NM_198427
BCAN

brevican

chr1_+_26609819 2.179 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr19_-_53706644 2.161


chr2_+_113973130 2.157 NM_012184
FOXD4L1
forkhead box D4-like 1
chr12_+_6800950 2.133 NM_014449
NM_019858
GPR162

G protein-coupled receptor 162

chr21_-_27261276 2.113 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr9_-_110969310 2.112 NM_014334
C9orf4
chromosome 9 open reading frame 4
chr8_-_144583718 2.106 NM_201589
MAFA
v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chrX_+_136475979 2.068 NM_003413
ZIC3
Zic family member 3 (odd-paired homolog, Drosophila)
chr11_-_132318741 2.060 OPCML
opioid binding protein/cell adhesion molecule-like
chr8_-_21702273 2.045 NM_001165038
NM_001165039
NM_001495
GFRA2


GDNF family receptor alpha 2


chr19_-_19233370 2.011 HAPLN4
hyaluronan and proteoglycan link protein 4
chr19_-_60350122 1.994 TNNT1
troponin T type 1 (skeletal, slow)
chr19_+_52215982 1.994 NM_002517
NPAS1
neuronal PAS domain protein 1
chr8_-_140784416 1.973 NM_016601
KCNK9
potassium channel, subfamily K, member 9
chr19_+_659766 1.965 NM_001040134
NM_002579
PALM

paralemmin

chr6_+_69401660 1.962 NM_001704
BAI3
brain-specific angiogenesis inhibitor 3
chr8_+_1909437 1.949 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr1_+_20751518 1.948 NM_207334
FAM43B
family with sequence similarity 43, member B
chr12_+_101875581 1.939 NM_004316
ASCL1
achaete-scute complex homolog 1 (Drosophila)
chr11_-_31782169 1.938 PAX6
paired box 6
chr4_+_4912272 1.936 NM_002448
MSX1
msh homeobox 1
chr12_+_6807831 1.928 NM_014262
LEPREL2
leprecan-like 2
chr11_+_61479182 1.926 BEST1
bestrophin 1
chr1_-_103346482 1.923 COL11A1
collagen, type XI, alpha 1
chr14_-_20636909 1.918 NM_001101672
ZNF219
zinc finger protein 219
chr11_-_88436463 1.917 NM_000842
GRM5
glutamate receptor, metabotropic 5
chr15_+_78483624 1.912 NM_014862
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr20_+_19141282 1.908 NM_020689
SLC24A3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr5_-_63293715 1.895 HTR1A
5-hydroxytryptamine (serotonin) receptor 1A
chrX_+_12066505 1.895 NM_014728
FRMPD4
FERM and PDZ domain containing 4
chr10_+_102495327 1.892 NM_000278
NM_003987
NM_003988
NM_003989
NM_003990
PAX2




paired box 2




chr3_-_140148671 1.887 NM_023067
FOXL2
forkhead box L2
chr7_-_19123787 1.887 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr21_+_33364316 1.874 NM_138983
OLIG1
oligodendrocyte transcription factor 1
chr3_+_53504070 1.862 NM_000720
NM_001128839
NM_001128840
CACNA1D


calcium channel, voltage-dependent, L type, alpha 1D subunit


chrX_-_50230329 1.856 NM_001013742
DGKK
diacylglycerol kinase, kappa
chr22_+_47350781 1.855 NM_015381
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr11_-_64268841 1.855 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_+_7252225 1.822 NM_020795
NLGN2
neuroligin 2
chr5_+_82803248 1.820 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr17_-_60986905 1.809 AXIN2
axin 2
chr17_+_35036936 1.801 PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr4_+_93444572 1.798 NM_001510
GRID2
glutamate receptor, ionotropic, delta 2
chr2_-_219558517 1.798 NM_017521
FEV
FEV (ETS oncogene family)
chr12_+_56291484 1.786 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr19_+_56506907 1.785 NM_001101372
IGLON5
IgLON family member 5
chrX_+_71047344 1.784 NM_001013627
NHSL2
NHS-like 2
chr17_+_26742767 1.782 NM_032932
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr19_-_52667056 1.781 NM_015063
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr13_+_99432258 1.774 NM_007129
ZIC2
Zic family member 2 (odd-paired homolog, Drosophila)
chr6_+_133604181 1.770 NM_004100
NM_172103
NM_172105
EYA4


eyes absent homolog 4 (Drosophila)


chr10_+_83625049 1.770 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr15_+_58083798 1.766 FOXB1
forkhead box B1
chr19_-_242335 1.766 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr17_+_56884560 1.766 TBX4
T-box 4
chr11_-_64269501 1.753 NM_153819
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr10_+_50488352 1.751 NM_003055
SLC18A3
solute carrier family 18 (vesicular acetylcholine), member 3
chr1_+_26609893 1.745 LIN28A
lin-28 homolog A (C. elegans)
chr11_-_27697768 1.743 NM_001143807
BDNF
brain-derived neurotrophic factor
chr6_+_87703742 1.742 NM_000865
HTR1E
5-hydroxytryptamine (serotonin) receptor 1E
chr6_+_133604203 1.730 EYA4
eyes absent homolog 4 (Drosophila)
chr5_-_9599157 1.724 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr8_-_144313293 1.723 NM_001130478
LY6H
lymphocyte antigen 6 complex, locus H
chr17_+_38166759 1.713 RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr16_+_85101734 1.712 FOXF1
forkhead box F1
chr16_+_2954217 1.706 NM_024507
NM_172229
KREMEN2

kringle containing transmembrane protein 2

chr15_+_58083737 1.703


chr9_-_121171400 1.691 NM_014618
DBC1
deleted in bladder cancer 1
chr19_-_11452439 1.690 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chrX_-_74062005 1.684 NM_001008537
KIAA2022
KIAA2022
chr1_-_103346639 1.680 NM_001190709
NM_001854
NM_080629
NM_080630
COL11A1



collagen, type XI, alpha 1



chr2_+_70981233 1.677 VAX2
ventral anterior homeobox 2
chr18_+_53170718 1.675 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr4_-_13158391 1.671 LOC285548
hypothetical LOC285548
chr14_-_62581656 1.669 NM_139318
NM_172375
KCNH5

potassium voltage-gated channel, subfamily H (eag-related), member 5

chr10_+_22650145 1.668 BMI1
BMI1 polycomb ring finger oncogene
chr2_-_219881937 1.666 PTPRN
protein tyrosine phosphatase, receptor type, N
chr17_+_8865547 1.666 NM_004822
NTN1
netrin 1
chr8_-_41624030 1.663 NM_152568
NKX6-3
NK6 homeobox 3
chr12_+_52618815 1.649 NM_017410
HOXC13
homeobox C13
chr3_+_140148765 1.649 NM_001040061
C3orf72
chromosome 3 open reading frame 72
chr17_-_72045218 1.647 NM_134268
CYGB
cytoglobin
chr22_-_49348193 1.643 NM_001123225
C22orf41
chromosome 22 open reading frame 41
chrX_-_6155887 1.639 NM_020742
NLGN4X
neuroligin 4, X-linked
chr14_-_36058648 1.631 NM_003317
NKX2-1
NK2 homeobox 1
chr12_+_52665196 1.630 NM_017409
HOXC10
homeobox C10
chr11_+_56984702 1.618 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr3_+_11009419 1.610 NM_003042
SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr1_+_154878498 1.607 BCAN
brevican
chr12_+_52689062 1.606 NM_022658
HOXC8
homeobox C8
chr4_-_168392307 1.605 NM_001040159
NM_016950
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr22_+_28206180 1.602 NM_021076
NEFH
neurofilament, heavy polypeptide
chr17_-_29930431 1.601 NM_207454
C17orf102
chromosome 17 open reading frame 102
chr11_-_44288188 1.601 NM_021926
ALX4
ALX homeobox 4
chr17_-_69151821 1.599 NM_001144952
SDK2
sidekick homolog 2 (chicken)
chr10_-_103525646 1.595 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr20_-_30534848 1.588 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr18_-_28606839 1.586 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr2_+_171280046 1.586 NM_001003845
SP5
Sp5 transcription factor
chr6_-_165996031 1.577 LOC100132188
LP7097
chr12_-_56312696 1.573 B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr12_+_55808696 1.559 LRP1
low density lipoprotein receptor-related protein 1
chr10_+_119291945 1.557 NM_001165924
NM_004098
EMX2

empty spiracles homeobox 2

chr11_-_68537243 1.555 NM_001098515
NM_145015
MRGPRF

MAS-related GPR, member F

chr4_-_11039600 1.552 NM_005114
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr4_+_41057600 1.546


chr1_+_47654330 1.545 NM_012186
FOXE3
forkhead box E3
chr2_+_233448739 1.544 C2orf82
chromosome 2 open reading frame 82
chr5_+_152850276 1.543 NM_000827
NM_001114183
GRIA1

glutamate receptor, ionotropic, AMPA 1

chr17_+_45993338 1.535 NM_018896
NM_198376
NM_198377
NM_198378
NM_198379
NM_198380
NM_198382
NM_198383
NM_198384
NM_198385
NM_198386
NM_198387
NM_198388
NM_198396
NM_198397
CACNA1G














calcium channel, voltage-dependent, T type, alpha 1G subunit














chrX_+_152565849 1.533 DUSP9
dual specificity phosphatase 9
chr10_-_103593529 1.523 NM_014591
NM_173191
NM_173192
NM_173193
NM_173195
NM_173197
KCNIP2





Kv channel interacting protein 2





chr14_-_98807307 1.520 BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr9_+_2612134 1.514 VLDLR
very low density lipoprotein receptor
chr4_-_5940893 1.505 CRMP1
collapsin response mediator protein 1
chr19_+_60487578 1.504 BRSK1
BR serine/threonine kinase 1
chr19_+_4229597 1.501 NM_020209
SHD
Src homology 2 domain containing transforming protein D
chr9_+_8848130 1.496


chr19_+_54361216 1.495 TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr20_-_3097070 1.493 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr11_-_57171554 1.488 YPEL4
yippee-like 4 (Drosophila)
chr14_-_23117614 1.488 JPH4
junctophilin 4
chr5_-_63293301 1.484 NM_000524
HTR1A
5-hydroxytryptamine (serotonin) receptor 1A
chr16_-_10184111 1.480 NM_000833
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr14_-_60260780 1.479 SIX4
SIX homeobox 4
chr19_-_56260135 1.478 NM_015596
KLK13
kallikrein-related peptidase 13
chr7_-_122961808 1.474 NM_178827
IQUB
IQ motif and ubiquitin domain containing
chr16_-_52877868 1.474 NM_024336
IRX3
iroquois homeobox 3
chr9_-_34579679 1.472 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr11_+_66939720 1.472 NM_001166222
NM_020811
CARNS1

carnosine synthase 1

chr12_-_6668680 1.469 ZNF384
zinc finger protein 384
chr16_-_2776606 1.465 NM_152891
PRSS33
protease, serine, 33
chr10_+_119292699 1.465


chr1_-_1465602 1.462 NM_001114748
C1orf70
chromosome 1 open reading frame 70

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.14 3.08e-25 GO:0065007 biological regulation
1.14 9.91e-25 GO:0050789 regulation of biological process
1.39 1.04e-23 GO:0007399 nervous system development
1.15 1.21e-23 GO:0050794 regulation of cellular process
1.08 7.64e-21 GO:0009987 cellular process
1.22 2.64e-18 GO:0007275 multicellular organismal development
1.20 5.02e-18 GO:0032502 developmental process
1.44 2.09e-17 GO:0022008 neurogenesis
1.34 2.75e-17 GO:0009653 anatomical structure morphogenesis
1.22 9.79e-17 GO:0048856 anatomical structure development
1.23 2.09e-16 GO:0048731 system development
1.27 2.60e-15 GO:0030154 cell differentiation
1.26 5.81e-15 GO:0048523 negative regulation of cellular process
1.19 7.94e-15 GO:0023052 signaling
1.42 1.55e-14 GO:0048699 generation of neurons
1.26 1.99e-14 GO:0048869 cellular developmental process
1.24 4.66e-14 GO:0048519 negative regulation of biological process
1.46 1.68e-13 GO:0009890 negative regulation of biosynthetic process
1.23 2.61e-13 GO:0048522 positive regulation of cellular process
1.22 2.81e-13 GO:0048518 positive regulation of biological process
1.18 5.86e-13 GO:0031323 regulation of cellular metabolic process
1.45 6.07e-13 GO:0030182 neuron differentiation
1.53 8.56e-13 GO:0000904 cell morphogenesis involved in differentiation
1.38 9.67e-13 GO:0048468 cell development
1.46 1.01e-12 GO:0010558 negative regulation of macromolecule biosynthetic process
1.45 1.73e-12 GO:0031327 negative regulation of cellular biosynthetic process
1.46 3.40e-12 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.38 4.57e-12 GO:0031324 negative regulation of cellular metabolic process
1.37 9.09e-12 GO:0010605 negative regulation of macromolecule metabolic process
1.36 1.47e-11 GO:0009892 negative regulation of metabolic process
1.35 3.39e-11 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.16 4.61e-11 GO:0019222 regulation of metabolic process
1.17 1.14e-10 GO:0080090 regulation of primary metabolic process
1.17 1.92e-10 GO:0060255 regulation of macromolecule metabolic process
1.44 2.91e-10 GO:0000902 cell morphogenesis
1.58 3.92e-10 GO:0007389 pattern specification process
1.42 5.05e-10 GO:0032989 cellular component morphogenesis
1.46 7.67e-10 GO:0045892 negative regulation of transcription, DNA-dependent
1.17 8.01e-10 GO:0007165 signal transduction
1.42 8.90e-10 GO:0051172 negative regulation of nitrogen compound metabolic process
1.45 9.57e-10 GO:0051253 negative regulation of RNA metabolic process
1.46 1.43e-09 GO:0007417 central nervous system development
1.42 1.71e-09 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.43 2.11e-09 GO:0048666 neuron development
1.28 2.12e-09 GO:0051239 regulation of multicellular organismal process
1.52 3.08e-09 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.34 3.54e-09 GO:0050793 regulation of developmental process
1.49 4.27e-09 GO:0048667 cell morphogenesis involved in neuron differentiation
1.40 4.28e-09 GO:0030030 cell projection organization
1.38 1.14e-08 GO:0009790 embryo development
1.18 1.34e-08 GO:0051171 regulation of nitrogen compound metabolic process
1.24 1.81e-08 GO:0023051 regulation of signaling
1.22 1.95e-08 GO:0048513 organ development
1.40 2.13e-08 GO:0010629 negative regulation of gene expression
1.45 2.15e-08 GO:0031175 neuron projection development
1.38 2.79e-08 GO:0045595 regulation of cell differentiation
1.12 3.43e-08 GO:0043170 macromolecule metabolic process
1.13 6.55e-08 GO:0044260 cellular macromolecule metabolic process
1.47 7.00e-08 GO:0007409 axonogenesis
1.46 7.60e-08 GO:0048812 neuron projection morphogenesis
1.17 9.07e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.13 1.52e-07 GO:0051716 cellular response to stimulus
1.17 1.67e-07 GO:0031326 regulation of cellular biosynthetic process
1.17 1.81e-07 GO:0009889 regulation of biosynthetic process
1.34 2.02e-07 GO:2000026 regulation of multicellular organismal development
1.38 2.56e-07 GO:0009887 organ morphogenesis
1.32 2.75e-07 GO:0009888 tissue development
1.17 3.19e-07 GO:0071842 cellular component organization at cellular level
1.48 4.95e-07 GO:0007420 brain development
1.41 4.98e-07 GO:0048858 cell projection morphogenesis
1.27 5.26e-07 GO:0010604 positive regulation of macromolecule metabolic process
1.24 6.50e-07 GO:0009966 regulation of signal transduction
1.35 1.25e-06 GO:0051254 positive regulation of RNA metabolic process
1.40 1.41e-06 GO:0032990 cell part morphogenesis
1.34 1.61e-06 GO:0010628 positive regulation of gene expression
1.32 2.46e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16 2.47e-06 GO:0071841 cellular component organization or biogenesis at cellular level
1.57 2.68e-06 GO:0003002 regionalization
1.51 2.84e-06 GO:0048729 tissue morphogenesis
1.17 2.88e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.24 3.04e-06 GO:0009893 positive regulation of metabolic process
1.35 3.70e-06 GO:0045893 positive regulation of transcription, DNA-dependent
1.17 3.94e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.25 4.67e-06 GO:0031325 positive regulation of cellular metabolic process
1.16 5.01e-06 GO:0010468 regulation of gene expression
1.31 5.27e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
1.14 5.92e-06 GO:0016043 cellular component organization
1.44 8.31e-06 GO:0048598 embryonic morphogenesis
1.29 8.46e-06 GO:0006351 transcription, DNA-dependent
1.13 1.38e-05 GO:0071840 cellular component organization or biogenesis
1.40 1.60e-05 GO:0051094 positive regulation of developmental process
1.50 2.03e-05 GO:0035295 tube development
1.65 3.17e-05 GO:0009952 anterior/posterior pattern formation
1.16 3.33e-05 GO:0051252 regulation of RNA metabolic process
2.25 6.12e-05 GO:0001656 metanephros development
1.57 1.04e-04 GO:0032582 negative regulation of gene-specific transcription
1.18 1.06e-04 GO:0048583 regulation of response to stimulus
1.36 1.33e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.28 1.80e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.24 1.91e-04 GO:0007154 cell communication
1.44 1.97e-04 GO:0060284 regulation of cell development
1.44 2.14e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.16 2.41e-04 GO:0006355 regulation of transcription, DNA-dependent
1.26 2.45e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.40 3.13e-04 GO:0009792 embryo development ending in birth or egg hatching
1.26 3.36e-04 GO:0008219 cell death
1.74 3.49e-04 GO:0001822 kidney development
1.40 3.77e-04 GO:0043009 chordate embryonic development
1.23 3.92e-04 GO:0042981 regulation of apoptosis
1.25 4.27e-04 GO:0016265 death
1.27 4.38e-04 GO:0007267 cell-cell signaling
1.23 5.77e-04 GO:0010941 regulation of cell death
1.25 5.98e-04 GO:0009891 positive regulation of biosynthetic process
1.23 5.99e-04 GO:0043067 regulation of programmed cell death
1.61 7.75e-04 GO:0045165 cell fate commitment
1.22 8.28e-04 GO:0010646 regulation of cell communication
1.70 9.26e-04 GO:0072001 renal system development
1.40 9.95e-04 GO:0007411 axon guidance
1.54 1.19e-03 GO:0035239 tube morphogenesis
1.40 1.29e-03 GO:0045597 positive regulation of cell differentiation
1.08 1.36e-03 GO:0044238 primary metabolic process
1.43 1.38e-03 GO:0061061 muscle structure development
1.16 1.41e-03 GO:0006464 protein modification process
1.17 1.42e-03 GO:0007166 cell surface receptor linked signaling pathway
2.04 1.71e-03 GO:0021510 spinal cord development
1.23 1.83e-03 GO:0032774 RNA biosynthetic process
1.47 1.96e-03 GO:0002009 morphogenesis of an epithelium
1.59 2.03e-03 GO:0001655 urogenital system development
1.34 2.31e-03 GO:0032583 regulation of gene-specific transcription
1.35 2.38e-03 GO:0009968 negative regulation of signal transduction
1.15 2.58e-03 GO:0065008 regulation of biological quality
1.54 2.59e-03 GO:0030900 forebrain development
1.24 2.77e-03 GO:0051128 regulation of cellular component organization
1.32 3.35e-03 GO:0019226 transmission of nerve impulse
1.32 3.35e-03 GO:0035637 multicellular organismal signaling
1.08 3.91e-03 GO:0032501 multicellular organismal process
1.07 4.67e-03 GO:0044237 cellular metabolic process
1.16 5.73e-03 GO:0016070 RNA metabolic process
2.03 6.47e-03 GO:0045995 regulation of embryonic development
1.15 6.61e-03 GO:0043412 macromolecule modification
1.32 6.62e-03 GO:0023057 negative regulation of signaling
1.54 7.28e-03 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
1.32 8.13e-03 GO:0010648 negative regulation of cell communication
1.32 8.67e-03 GO:0007268 synaptic transmission
1.78 9.32e-03 GO:2000027 regulation of organ morphogenesis
1.59 9.70e-03 GO:0001763 morphogenesis of a branching structure
1.37 1.02e-02 GO:0001501 skeletal system development
1.25 1.18e-02 GO:0006915 apoptosis
1.21 1.20e-02 GO:0032879 regulation of localization
1.43 1.27e-02 GO:0051129 negative regulation of cellular component organization
1.35 1.35e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.13 1.53e-02 GO:0090304 nucleic acid metabolic process
1.66 1.57e-02 GO:0048754 branching morphogenesis of a tube
1.24 1.71e-02 GO:0012501 programmed cell death
1.30 1.76e-02 GO:0072358 cardiovascular system development
1.30 1.76e-02 GO:0072359 circulatory system development
1.28 2.29e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.70 2.32e-02 GO:0007369 gastrulation
1.25 2.36e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.16 2.37e-02 GO:0065009 regulation of molecular function
1.33 2.42e-02 GO:0060429 epithelium development
1.71 2.44e-02 GO:0048706 embryonic skeletal system development
1.45 3.11e-02 GO:0007517 muscle organ development
1.52 3.21e-02 GO:0060562 epithelial tube morphogenesis
1.39 3.23e-02 GO:0045596 negative regulation of cell differentiation
1.62 3.31e-02 GO:0006836 neurotransmitter transport
1.19 3.63e-02 GO:0032268 regulation of cellular protein metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.36 2.36e-07 GO:0030054 cell junction
1.43 2.78e-07 GO:0045202 synapse
1.05 4.52e-07 GO:0044424 intracellular part
1.05 6.43e-07 GO:0005622 intracellular
1.07 9.12e-07 GO:0005737 cytoplasm
1.09 1.21e-05 GO:0005634 nucleus
1.39 1.81e-05 GO:0043005 neuron projection
1.50 2.34e-05 GO:0016323 basolateral plasma membrane
1.42 1.04e-04 GO:0044456 synapse part
1.15 1.21e-04 GO:0044459 plasma membrane part
1.15 1.51e-04 GO:0005829 cytosol
1.05 2.42e-04 GO:0043226 organelle
1.05 3.12e-04 GO:0043227 membrane-bounded organelle
1.05 4.18e-04 GO:0043231 intracellular membrane-bounded organelle
1.05 4.95e-04 GO:0043229 intracellular organelle
1.50 1.04e-03 GO:0030424 axon
1.42 1.15e-03 GO:0005667 transcription factor complex
1.23 1.42e-03 GO:0031982 vesicle
1.11 1.91e-03 GO:0043234 protein complex
1.21 3.64e-03 GO:0042995 cell projection
1.48 6.69e-03 GO:0030136 clathrin-coated vesicle
1.22 7.27e-03 GO:0031410 cytoplasmic vesicle
1.42 9.75e-03 GO:0030135 coated vesicle
1.13 1.07e-02 GO:0031981 nuclear lumen
1.22 1.12e-02 GO:0031988 membrane-bounded vesicle
1.64 1.29e-02 GO:0008021 synaptic vesicle
1.56 1.37e-02 GO:0030055 cell-substrate junction
1.45 1.52e-02 GO:0070161 anchoring junction
1.21 1.54e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.47 1.58e-02 GO:0005912 adherens junction
1.56 3.03e-02 GO:0005925 focal adhesion
1.02 3.17e-02 GO:0044464 cell part
1.02 3.39e-02 GO:0005623 cell
1.40 3.46e-02 GO:0030425 dendrite
1.38 3.50e-02 GO:0034702 ion channel complex
1.54 3.72e-02 GO:0005924 cell-substrate adherens junction
1.11 4.59e-02 GO:0044428 nuclear part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 1.98e-27 GO:0005515 protein binding
1.47 9.64e-16 GO:0043565 sequence-specific DNA binding
1.38 5.45e-15 GO:0030528 transcription regulator activity
1.06 5.61e-13 GO:0005488 binding
1.31 1.77e-09 GO:0001071 nucleic acid binding transcription factor activity
1.31 1.77e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
1.64 1.38e-07 GO:0010843 promoter binding
1.60 6.57e-07 GO:0000975 regulatory region DNA binding
1.60 6.57e-07 GO:0001067 regulatory region nucleic acid binding
1.60 6.57e-07 GO:0044212 transcription regulatory region DNA binding
1.49 1.47e-06 GO:0008134 transcription factor binding
1.39 4.16e-06 GO:0019904 protein domain specific binding
1.33 2.39e-05 GO:0008092 cytoskeletal protein binding
1.42 9.33e-05 GO:0016563 transcription activator activity
1.42 1.48e-04 GO:0016564 transcription repressor activity
1.56 2.45e-03 GO:0003690 double-stranded DNA binding
1.48 2.85e-03 GO:0043566 structure-specific DNA binding
1.64 2.61e-02 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.49 2.85e-02 GO:0022843 voltage-gated cation channel activity
1.60 3.02e-02 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
1.36 3.56e-02 GO:0003702 RNA polymerase II transcription factor activity
1.18 3.78e-02 GO:0030234 enzyme regulator activity
1.29 4.58e-02 GO:0008047 enzyme activator activity