Motif ID: MZF1.p2

Z-value: 3.317


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_637759010.185.0e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_159306532 9.549 NM_001163678
NM_003030
NM_006884
 SHOX2


short stature homeobox 2


chr7_+_5289079 6.280 NM_001040661
NM_153247
 SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr3_-_159306214 5.636


chr8_+_22513043 4.878 NM_001013842
NM_001198827
NM_173686
 C8orf58


chromosome 8 open reading frame 58


chr1_+_2975590 4.766 NM_022114
NM_199454
 PRDM16

PR domain containing 16

chr22_-_28972683 4.676 NM_002309
 LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr3_+_148610516 4.614 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr2_+_45022540 4.468 NM_005413
 SIX3
SIX homeobox 3
chr11_+_17714070 4.456 NM_001112741
NM_004976
 KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr2_-_200030944 4.400 NM_001172509
 SATB2
SATB homeobox 2
chr13_+_113574925 4.253 NM_001143945
 GAS6
growth arrest-specific 6
chr4_-_1156959 4.142 NM_001128325
 SPON2
spondin 2, extracellular matrix protein
chr4_-_1156533 3.996 NM_012445
 SPON2
spondin 2, extracellular matrix protein
chr2_+_104837004 3.832


chr4_-_46086528 3.831 NM_000807
 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr14_-_60185659 3.774 NM_005982
 SIX1
SIX homeobox 1
chr6_-_32227645 3.645 PRRT1
proline-rich transmembrane protein 1
chr4_-_1156378 3.603 SPON2
spondin 2, extracellular matrix protein
chr21_+_42946719 3.594 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
 PDE9A



















phosphodiesterase 9A



















chr2_+_5750229 3.482 NM_003108
 SOX11
SRY (sex determining region Y)-box 11

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 167 entries
enrichment   p-value GO term description
2.25 6.12e-05 GO:0001656 metanephros development
2.04 1.71e-03 GO:0021510 spinal cord development
2.03 6.47e-03 GO:0045995 regulation of embryonic development
1.78 9.32e-03 GO:2000027 regulation of organ morphogenesis
1.74 3.49e-04 GO:0001822 kidney development
1.71 2.44e-02 GO:0048706 embryonic skeletal system development
1.70 9.26e-04 GO:0072001 renal system development
1.70 2.32e-02 GO:0007369 gastrulation
1.66 1.57e-02 GO:0048754 branching morphogenesis of a tube
1.65 3.17e-05 GO:0009952 anterior/posterior pattern formation
1.62 3.31e-02 GO:0006836 neurotransmitter transport
1.61 7.75e-04 GO:0045165 cell fate commitment
1.59 2.03e-03 GO:0001655 urogenital system development
1.59 9.70e-03 GO:0001763 morphogenesis of a branching structure
1.58 3.92e-10 GO:0007389 pattern specification process
1.57 2.68e-06 GO:0003002 regionalization
1.57 1.04e-04 GO:0032582 negative regulation of gene-specific transcription
1.54 1.19e-03 GO:0035239 tube morphogenesis
1.54 2.59e-03 GO:0030900 forebrain development
1.54 7.28e-03 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter

Gene overrepresentation in compartment category:

Showing 1 to 20 of 37 entries
enrichment   p-value GO term description
1.64 1.29e-02 GO:0008021 synaptic vesicle
1.56 1.37e-02 GO:0030055 cell-substrate junction
1.56 3.03e-02 GO:0005925 focal adhesion
1.54 3.72e-02 GO:0005924 cell-substrate adherens junction
1.50 2.34e-05 GO:0016323 basolateral plasma membrane
1.50 1.04e-03 GO:0030424 axon
1.48 6.69e-03 GO:0030136 clathrin-coated vesicle
1.47 1.58e-02 GO:0005912 adherens junction
1.45 1.52e-02 GO:0070161 anchoring junction
1.43 2.78e-07 GO:0045202 synapse
1.42 1.04e-04 GO:0044456 synapse part
1.42 1.15e-03 GO:0005667 transcription factor complex
1.42 9.75e-03 GO:0030135 coated vesicle
1.40 3.46e-02 GO:0030425 dendrite
1.39 1.81e-05 GO:0043005 neuron projection
1.38 3.50e-02 GO:0034702 ion channel complex
1.36 2.36e-07 GO:0030054 cell junction
1.23 1.42e-03 GO:0031982 vesicle
1.22 7.27e-03 GO:0031410 cytoplasmic vesicle
1.22 1.12e-02 GO:0031988 membrane-bounded vesicle

Gene overrepresentation in function category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
1.64 1.38e-07 GO:0010843 promoter binding
1.64 2.61e-02 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.60 6.57e-07 GO:0000975 regulatory region DNA binding
1.60 6.57e-07 GO:0001067 regulatory region nucleic acid binding
1.60 6.57e-07 GO:0044212 transcription regulatory region DNA binding
1.60 3.02e-02 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
1.56 2.45e-03 GO:0003690 double-stranded DNA binding
1.49 1.47e-06 GO:0008134 transcription factor binding
1.49 2.85e-02 GO:0022843 voltage-gated cation channel activity
1.48 2.85e-03 GO:0043566 structure-specific DNA binding
1.47 9.64e-16 GO:0043565 sequence-specific DNA binding
1.42 9.33e-05 GO:0016563 transcription activator activity
1.42 1.48e-04 GO:0016564 transcription repressor activity
1.39 4.16e-06 GO:0019904 protein domain specific binding
1.38 5.45e-15 GO:0030528 transcription regulator activity
1.36 3.56e-02 GO:0003702 RNA polymerase II transcription factor activity
1.33 2.39e-05 GO:0008092 cytoskeletal protein binding
1.31 1.77e-09 GO:0001071 nucleic acid binding transcription factor activity
1.31 1.77e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
1.29 4.58e-02 GO:0008047 enzyme activator activity