• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities
• All promoters sorted by FOV

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: NANOG.p2

Z-value: 0.890

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_40632456	0.892	NM_005306	FFAR2	free fatty acid receptor 2
chr18_+_18989786	0.816	NM_138375	CABLES1	Cdk5 and Abl enzyme substrate 1
chr1_-_109957195	0.713	NM_005272	GNAT2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr6_+_131613196	0.673	NM_004842 NM_138633	AKAP7	A kinase (PRKA) anchor protein 7
chr12_-_51114372	0.657	NM_004693	KRT75	keratin 75
chr1_-_116185215	0.642	NM_005599	NHLH2	nescient helix loop helix 2
chr13_+_97856148	0.609
chr4_-_186815116	0.604	NM_001145674 NM_001145675	SORBS2	sorbin and SH3 domain containing 2
chr21_+_43024936	0.600		PDE9A	phosphodiesterase 9A
chr3_-_71860958	0.592	NM_001134650	EIF4E3	eukaryotic translation initiation factor 4E family member 3
chr4_+_71806538	0.584	NM_001037442 NM_014961	RUFY3	RUN and FYVE domain containing 3
chr2_+_157822355	0.575	NM_014568	GALNT5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr7_-_96471544	0.556		DLX6-AS1	DLX6 antisense RNA 1 (non-protein coding)
chr2_-_98646367	0.552	NM_001160154	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr2_+_17861266	0.537	NM_001105569	MSGN1	mesogenin 1
chr10_-_14412813	0.528	NM_018027	FRMD4A	FERM domain containing 4A
chr3_+_130730171	0.489	NM_000539	RHO	rhodopsin
chr12_-_108736983	0.472	NM_001177431 NM_001177428 NM_001177433 NM_147204	TRPV4	transient receptor potential cation channel, subfamily V, member 4
chr7_+_128802719	0.468	NM_001130722	AHCYL2	adenosylhomocysteinase-like 2
chr7_+_116238309	0.457		CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2
chr12_-_6103945	0.455	NM_000552	VWF	von Willebrand factor
chr6_-_42798286	0.454	NM_000322	PRPH2	peripherin 2 (retinal degeneration, slow)
chr19_+_53016910	0.433	NM_000554	CRX	cone-rod homeobox
chr8_+_67201684	0.427	NM_033058 NM_184085 NM_184086 NM_184087	TRIM55	tripartite motif containing 55
chr7_-_36992221	0.424	NM_130442	ELMO1	engulfment and cell motility 1
chr3_-_11598829	0.413	NM_001128220	VGLL4	vestigial like 4 (Drosophila)
chr5_-_168204430	0.408
chr7_+_141054621	0.408	NM_001105558	WEE2	WEE1 homolog 2 (S. pombe)
chr9_-_132759045	0.388	NM_198180	QRFP	pyroglutamylated RFamide peptide
chr5_+_140703784	0.386	NM_018916 NM_032011	PCDHGA3	protocadherin gamma subfamily A, 3
chr3_+_161040439	0.383		SCHIP1	schwannomin interacting protein 1
chr11_-_58736897	0.380	NM_001039396	MPEG1	macrophage expressed 1
chr5_+_176744037	0.375	NM_001167579 NM_003052	SLC34A1	solute carrier family 34 (sodium phosphate), member 1
chr16_+_6763810	0.374	NM_001142334	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr15_-_53350383	0.374	NM_183236	RAB27A	RAB27A, member RAS oncogene family
chr21_-_30836051	0.371	NM_181612	KRTAP19-6	keratin associated protein 19-6
chr16_+_6473759	0.369		RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_-_40272239	0.360	NM_020929	LRRC4C	leucine rich repeat containing 4C
chrX_-_19727828	0.360	NM_001024666	SH3KBP1	SH3-domain kinase binding protein 1
chr1_+_15862887	0.358
chr11_+_7574992	0.357		PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_-_230717850	0.355	NM_020808	SIPA1L2	signal-induced proliferation-associated 1 like 2
chr1_+_559618	0.352
chr1_-_42156957	0.349		HIVEP3	human immunodeficiency virus type I enhancer binding protein 3
chr15_-_91078307	0.348		FAM174B	family with sequence similarity 174, member B
chr9_-_5294579	0.348	NM_005059 NM_134441	RLN2	relaxin 2
chr17_-_36418869	0.346	NM_031958	KRTAP3-1	keratin associated protein 3-1
chr4_+_3341521	0.342	NM_198227	RGS12	regulator of G-protein signaling 12
chr1_+_154386358	0.339	NM_001193301	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr5_+_127012611	0.337	NM_001048252	CTXN3	cortexin 3
chr1_-_50661716	0.335	NM_032110	DMRTA2	DMRT-like family A2
chr7_-_13992351	0.335	NM_001163150 NM_001163151 NM_001163152	ETV1	ets variant 1
chr2_+_96269703	0.332	NM_001037228	LOC285033	hypothetical protein LOC285033
chr17_-_44400952	0.330	NM_004123	GIP	gastric inhibitory polypeptide
chr1_-_30977931	0.324		LAPTM5	lysosomal protein transmembrane 5
chr18_+_13601664	0.320	NM_001003674 NM_001003675	C18orf1	chromosome 18 open reading frame 1
chr6_+_88026338	0.320		ZNF292	zinc finger protein 292
chr1_-_42156913	0.318
chr21_-_26294332	0.314		APP	amyloid beta (A4) precursor protein
chrX_-_19727775	0.308		SH3KBP1	SH3-domain kinase binding protein 1
chr12_+_45896511	0.308		FAM113B	family with sequence similarity 113, member B
chr20_+_43691797	0.307	NM_080753	WFDC10A	WAP four-disulfide core domain 10A
chr4_-_40631397	0.307		APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2
chr1_+_42934910	0.305		YBX1	Y box binding protein 1
chr1_-_153109349	0.303	NM_002249	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr1_+_196874839	0.303		PTPRC	protein tyrosine phosphatase, receptor type, C
chr11_-_17147863	0.301	NM_002645	PIK3C2A	phosphoinositide-3-kinase, class 2, alpha polypeptide
chr9_+_115265827	0.300	NM_017790	RGS3	regulator of G-protein signaling 3
chr1_-_42157077	0.299	NM_001127714 NM_024503	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3
chr10_-_74384485	0.295	NM_032562	PLA2G12B	phospholipase A2, group XIIB
chr1_-_120285753	0.293		NOTCH2	notch 2
chr5_+_125786975	0.286		GRAMD3	GRAM domain containing 3
chr4_+_77575276	0.284	NM_020859	SHROOM3	shroom family member 3
chr3_-_21767819	0.283	NM_024697	ZNF385D	zinc finger protein 385D
chr18_-_50134940	0.281	NM_139171	STARD6	StAR-related lipid transfer (START) domain containing 6
chr3_-_116272911	0.278	NM_001164343	ZBTB20	zinc finger and BTB domain containing 20
chr2_-_110665188	0.275	NM_033514	LIMS3-LOC440895 LIMS3	LIMS3-LOC440895 read-through LIM and senescent cell antigen-like domains 3
chr1_-_154484341	0.275	NM_198406 NM_024897	PAQR6	progestin and adipoQ receptor family member VI
chr7_+_104468614	0.274		MLL5	myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr8_-_40874485	0.272	NM_001135731 NM_024645	ZMAT4	zinc finger, matrin-type 4
chr5_+_140848905	0.270	NM_018929 NM_032407	PCDHGC5	protocadherin gamma subfamily C, 5
chr15_-_53349775	0.268	NM_183234 NM_004580	RAB27A	RAB27A, member RAS oncogene family
chr1_+_20489998	0.268	NM_001039500	VWA5B1	von Willebrand factor A domain containing 5B1
chr12_-_14740694	0.267	NM_004963	GUCY2C	guanylate cyclase 2C (heat stable enterotoxin receptor)
chr6_+_34314545	0.264	NM_145905	HMGA1	high mobility group AT-hook 1
chr1_+_180836050	0.261
chr7_-_107930170	0.259		PNPLA8	patatin-like phospholipase domain containing 8
chr4_+_110968594	0.254	NM_006583	RRH	retinal pigment epithelium-derived rhodopsin homolog
chr8_-_7275061	0.251	NM_018661	DEFB103B	defensin, beta 103B
chr10_+_49279647	0.251	NM_002750 NM_139046 NM_139047 NM_139049	MAPK8	mitogen-activated protein kinase 8
chr12_-_4358968	0.251	NM_020638	FGF23	fibroblast growth factor 23
chr6_-_31215089	0.250	NM_014069	PSORS1C2	psoriasis susceptibility 1 candidate 2
chr7_+_156716694	0.248
chr3_+_130014957	0.248		RAB7A	RAB7A, member RAS oncogene family
chr3_-_120861959	0.247	NM_022135	POPDC2	popeye domain containing 2
chr16_+_8714326	0.247	NM_000663	ABAT	4-aminobutyrate aminotransferase
chr12_-_51457371	0.247	NM_015848	KRT76	keratin 76
chr3_-_124893875	0.244		MYLK	myosin light chain kinase
chr13_-_31784088	0.240	NM_001136571	ZAR1L	zygote arrest 1-like
chr5_+_140790510	0.236		PCDHGA12	protocadherin gamma subfamily A, 12
chr3_+_161040343	0.236	NM_001197109	SCHIP1	schwannomin interacting protein 1
chr17_-_46479127	0.234		SPAG9	sperm associated antigen 9
chr10_-_74384569	0.234		PLA2G12B	phospholipase A2, group XIIB
chr5_+_125786717	0.231	NM_001146320 NM_001146321 NM_023927	GRAMD3	GRAM domain containing 3
chr2_+_170742900	0.230	NM_001083615 NM_001171642 NM_138995	MYO3B	myosin IIIB
chr10_+_11246934	0.228	NM_001025076 NM_001083591	CELF2	CUGBP, Elav-like family member 2
chr7_+_94135384	0.228		PEG10	paternally expressed 10
chr12_-_52281050	0.224	NM_001130059	ATF7	activating transcription factor 7
chr5_-_132228375	0.224	NM_005260	GDF9	growth differentiation factor 9
chr10_+_82163568	0.223		C10orf58	chromosome 10 open reading frame 58
chr1_+_196874759	0.223	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr7_+_147918589	0.223	NM_145304	C7orf33	chromosome 7 open reading frame 33
chr7_+_63411813	0.221		ZNF736	zinc finger protein 736
chr5_+_137701122	0.221	NM_001135647	FAM53C	family with sequence similarity 53, member C
chr13_-_98708549	0.221	NM_001098200 NM_005292	GPR18	G protein-coupled receptor 18
chr4_+_114433551	0.221		ANK2	ankyrin 2, neuronal
chr2_+_171280182	0.219
chr12_+_52105131	0.219		AMHR2	anti-Mullerian hormone receptor, type II
chr12_+_25096755	0.219		LRMP	lymphoid-restricted membrane protein
chr17_-_36456949	0.218	NM_001123387	KRTAP2-1	keratin associated protein 2-1
chr1_-_20178680	0.217	NM_001161729	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)
chr3_+_63859114	0.216	NM_001177387	ATXN7	ataxin 7
chr13_+_112825113	0.216	NM_000504	F10	coagulation factor X
chr8_+_26569709	0.212		DPYSL2	dihydropyrimidinase-like 2
chr1_-_201321711	0.211		MYOG	myogenin (myogenic factor 4)
chr3_+_46594079	0.210	NM_003212	TDGF1	teratocarcinoma-derived growth factor 1
chr11_+_123986661	0.209	NM_052959	PANX3	pannexin 3
chr2_-_55090759	0.207	NM_007008	RTN4	reticulon 4
chr8_-_67253234	0.207	NM_000756	CRH	corticotropin releasing hormone
chr6_+_143971009	0.205	NM_001100166 NM_014721	PHACTR2	phosphatase and actin regulator 2
chr5_+_140790365	0.203		PCDHGA12	protocadherin gamma subfamily A, 12
chr6_+_155579788	0.200	NM_001010927	TIAM2	T-cell lymphoma invasion and metastasis 2
chr5_+_156628929	0.199	NM_014376	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr4_-_15686838	0.199	NM_001145849 NM_001145850 NM_001145851 NM_001145852 NM_006017	PROM1	prominin 1
chr2_+_161981046	0.199		TBR1	T-box, brain, 1
chr6_+_167624792	0.199	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr12_+_108061584	0.198	NM_001093	ACACB	acetyl-CoA carboxylase beta
chr17_-_1195096	0.198		PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr2_-_37228452	0.198	NM_001135652	EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2
chr16_-_29817841	0.197	NM_001114099 NM_001114100 NM_012410 NM_201575	SEZ6L2	seizure related 6 homolog (mouse)-like 2
chr3_+_153074118	0.195	NM_033050	SUCNR1	succinate receptor 1
chr1_+_151456683	0.194	NM_001195571	PRR9	proline rich 9
chr12_+_50981915	0.193	NM_002284	KRT86	keratin 86
chr3_+_16191159	0.191	NM_054110	GALNTL2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2
chr3_-_180467483	0.191	NM_001163677 NM_171828	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr11_+_4427100	0.188	NM_001005172	OR52K2	olfactory receptor, family 52, subfamily K, member 2
chr5_-_24535386	0.187	NM_001190450	CDH10	cadherin 10, type 2 (T2-cadherin)
chr3_-_42892636	0.187	NM_004391	CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1
chr7_-_107667728	0.186	NM_001037132	NRCAM	neuronal cell adhesion molecule
chr14_-_104330982	0.186	NM_005163	AKT1	v-akt murine thymoma viral oncogene homolog 1
chr6_-_87861492	0.186	NM_000735	CGA	glycoprotein hormones, alpha polypeptide
chr17_+_4795128	0.186	NM_001193503 NM_001976 NM_053013	ENO3	enolase 3 (beta, muscle)
chr17_-_36209672	0.185	NM_181535	KRT28	keratin 28
chr11_+_65740789	0.182		PACS1	phosphofurin acidic cluster sorting protein 1
chr14_+_69307914	0.181		SRSF5	serine/arginine-rich splicing factor 5
chr7_-_99555399	0.181	NM_001190415	TAF6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr1_+_165564904	0.180	NM_001198783	POU2F1	POU class 2 homeobox 1
chr6_-_114490701	0.178	NM_153612	HS3ST5	heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr5_-_43326922	0.178		HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr22_-_39189369	0.178		MKL1	megakaryoblastic leukemia (translocation) 1
chr3_-_124822113	0.176	NM_053031 NM_053032	MYLK	myosin light chain kinase
chr10_+_35524835	0.176	NM_182721 NM_182722 NM_182723 NM_182724 NM_182725	CREM	cAMP responsive element modulator
chrX_+_71280758	0.176	NM_207422	FLJ44635	TPT1-like protein
chr14_+_77939845	0.176	NM_004796	NRXN3	neurexin 3
chr1_-_203579932	0.175		KLHDC8A	kelch domain containing 8A
chr5_-_35974493	0.175	NM_001042625 NM_144647	CAPSL	calcyphosine-like
chr17_-_36475652	0.174	NM_033184	KRTAP2-4	keratin associated protein 2-4
chr3_+_138132006	0.174	NM_001190796	NCK1	NCK adaptor protein 1
chr16_+_28797309	0.174	NM_004320 NM_173201	ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr12_+_50342814	0.174	NM_001177984	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit
chr8_+_32905027	0.174
chr4_+_71418886	0.171	NM_212557	AMTN	amelotin
chr17_-_9870292	0.170	NM_001130831	GAS7	growth arrest-specific 7
chr17_+_38306339	0.169	NM_000151	G6PC	glucose-6-phosphatase, catalytic subunit
chr1_+_165565006	0.168		POU2F1	POU class 2 homeobox 1
chr3_+_154362726	0.166		RAP2B	RAP2B, member of RAS oncogene family
chr5_+_140790310	0.166	NM_003735 NM_032094	PCDHGA12	protocadherin gamma subfamily A, 12
chr19_+_9064854	0.165	NM_001004456	OR1M1	olfactory receptor, family 1, subfamily M, member 1
chr19_+_49147219	0.164	NM_013359	ZNF221	zinc finger protein 221
chr14_-_79748273	0.163	NM_000793 NM_013989	DIO2	deiodinase, iodothyronine, type II
chr3_+_157877146	0.163	NM_001184718	TIPARP	TCDD-inducible poly(ADP-ribose) polymerase
chr5_-_149446182	0.163		CSF1R	colony stimulating factor 1 receptor
chr11_-_110755112	0.162		POU2AF1	POU class 2 associating factor 1
chr2_-_27967458	0.161		LOC100302650	hypothetical LOC100302650
chr11_-_70350509	0.161		SHANK2	SH3 and multiple ankyrin repeat domains 2
chrX_+_134482212	0.161	NM_182540	DDX26B	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr5_+_140460240	0.159	NM_018937	PCDHB3	protocadherin beta 3
chr7_-_115458010	0.159	NM_001018058 NM_012252	TFEC	transcription factor EC
chr2_-_165133239	0.158		GRB14	growth factor receptor-bound protein 14
chr1_-_155336223	0.156	NM_001004341	ETV3L	ets variant 3-like
chr1_+_242283129	0.156	NM_006352	ZNF238	zinc finger protein 238
chr3_-_184756101	0.155	NM_130446	KLHL6	kelch-like 6 (Drosophila)
chr2_+_171280046	0.155	NM_001003845	SP5	Sp5 transcription factor
chr1_+_109884016	0.155	NM_031936	GPR61	G protein-coupled receptor 61
chr17_-_19290745	0.154
chr6_-_33268177	0.154	NM_001163771 NM_080679 NM_080680 NM_080681	COL11A2	collagen, type XI, alpha 2
chr7_+_129771865	0.154	NM_001127441 NM_001127442 NM_080385	CPA5	carboxypeptidase A5
chrX_+_21960841	0.153	NM_000444	PHEX	phosphate regulating endopeptidase homolog, X-linked
chr1_-_158098962	0.152	NM_001013661	VSIG8	V-set and immunoglobulin domain containing 8
chr20_+_58004811	0.152	NM_021810	CDH26	cadherin 26

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.43	3.85e-09	GO:0032501	multicellular organismal process
1.46	3.38e-06	GO:0032502	developmental process
1.50	8.02e-06	GO:0048856	anatomical structure development
1.46	1.89e-05	GO:0007275	multicellular organismal development
1.50	1.01e-04	GO:0048731	system development
2.15	1.53e-04	GO:0045595	regulation of cell differentiation
1.63	6.83e-04	GO:0003008	system process
1.84	4.33e-03	GO:0050793	regulation of developmental process
1.54	5.18e-03	GO:0048513	organ development
1.61	9.28e-03	GO:0007399	nervous system development
1.83	1.22e-02	GO:0007600	sensory perception
2.17	1.73e-02	GO:0051094	positive regulation of developmental process
1.61	2.23e-02	GO:0050877	neurological system process
2.34	3.00e-02	GO:0045597	positive regulation of cell differentiation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
3.73	1.87e-06	GO:0005882	intermediate filament
3.48	2.46e-06	GO:0045111	intermediate filament cytoskeleton
4.80	4.61e-05	GO:0045095	keratin filament
1.30	3.35e-03	GO:0005886	plasma membrane
1.29	4.14e-03	GO:0071944	cell periphery

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.71	2.92e-02	GO:0004930	G-protein coupled receptor activity

---