Motif ID: NFATC1..3.p2

Z-value: 2.034


Transcription factors associated with NFATC1..3.p2:

Gene SymbolEntrez IDGene Name
NFATC1 4772 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 4773 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 4775 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFATC2chr20_-_49592654-0.533.5e-02Click!
NFATC1chr18_+_75354312-0.322.2e-01Click!
NFATC3chr16_+_66676833-0.039.0e-01Click!


Activity profile for motif NFATC1..3.p2.

activity profile for motif NFATC1..3.p2


Sorted Z-values histogram for motif NFATC1..3.p2

Sorted Z-values for motif NFATC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFATC1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_150533948 2.078 NM_001184723
NM_138786
 TM4SF18

transmembrane 4 L six family member 18

chr1_+_24518398 1.831 NM_198173
NM_198174
 GRHL3

grainyhead-like 3 (Drosophila)

chr1_-_203657803 1.781 NM_001001552
NM_001199050
NM_001199051
NM_001199052
 LEMD1



LEM domain containing 1



chr4_-_77147625 1.633 NM_002416
 CXCL9
chemokine (C-X-C motif) ligand 9
chr11_+_113280727 1.605 NM_006028
 HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr6_-_2580296 1.590 NM_152554
 C6orf195
chromosome 6 open reading frame 195
chr2_+_178893216 1.576 NM_145739
 OSBPL6
oxysterol binding protein-like 6
chr18_-_51219880 1.567 TCF4
transcription factor 4
chr2_+_69055208 1.549 NM_019617
 GKN1
gastrokine 1
chr6_-_132980901 1.548 NM_014626
 TAAR2
trace amine associated receptor 2
chr1_+_24518501 1.533 NM_001195010
 GRHL3
grainyhead-like 3 (Drosophila)
chr10_-_116434364 1.520 NM_001003407
NM_001003408
 ABLIM1

actin binding LIM protein 1

chr5_+_38481392 1.456 NM_182801
 EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr4_-_100575313 1.409 NM_001166504
NM_000673
 ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr11_-_124311512 1.363 NM_152722
 HEPACAM
hepatic and glial cell adhesion molecule
chr12_+_32578513 1.356 FGD4
FYVE, RhoGEF and PH domain containing 4
chr11_-_85115105 1.341 NM_206927
NM_206928
 SYTL2

synaptotagmin-like 2

chr8_-_134141586 1.321 NM_006748
 SLA
Src-like-adaptor
chr18_+_18989786 1.272 NM_138375
 CABLES1
Cdk5 and Abl enzyme substrate 1
chr18_+_27281729 1.225 NM_001944
 DSG3
desmoglein 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.80 7.75e-06 GO:0007608 sensory perception of smell
1.79 1.43e-06 GO:0007606 sensory perception of chemical stimulus
1.51 7.16e-05 GO:0007600 sensory perception
1.32 1.45e-02 GO:0050877 neurological system process
1.14 6.93e-04 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.81 3.90e-02 GO:0070161 anchoring junction
1.43 9.67e-04 GO:0005615 extracellular space
1.41 1.12e-04 GO:0044421 extracellular region part
1.28 1.10e-04 GO:0005576 extracellular region
1.19 1.39e-05 GO:0071944 cell periphery
1.19 1.65e-05 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.85 6.26e-07 GO:0004984 olfactory receptor activity
1.75 4.62e-02 GO:0005125 cytokine activity
1.48 8.01e-05 GO:0004930 G-protein coupled receptor activity
1.31 8.50e-03 GO:0004888 transmembrane receptor activity
1.26 1.12e-03 GO:0004871 signal transducer activity
1.26 1.12e-03 GO:0060089 molecular transducer activity
1.26 9.74e-03 GO:0004872 receptor activity