Motif ID: NKX2-3_NKX2-5.p2

Z-value: 0.984


Transcription factors associated with NKX2-3_NKX2-5.p2:

Gene SymbolEntrez IDGene Name
NKX2-3 159296 NK2 transcription factor related, locus 3 (Drosophila)
NKX2-5 1482 NK2 transcription factor related, locus 5 (Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX2-5chr5_-_1725946910.523.9e-02Click!
NKX2-3chr10_+_101282679-0.058.6e-01Click!


Activity profile for motif NKX2-3_NKX2-5.p2.

activity profile for motif NKX2-3_NKX2-5.p2


Sorted Z-values histogram for motif NKX2-3_NKX2-5.p2

Sorted Z-values for motif NKX2-3_NKX2-5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-3_NKX2-5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_27171673 1.876 NM_152739
 HOXA9
homeobox A9
chrX_+_70682204 1.796 OGT
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr7_-_27171648 1.759 HOXA9
homeobox A9
chr7_-_27171600 1.664 HOXA9
homeobox A9
chr2_+_37282516 1.330 LOC100505876
hypothetical LOC100505876
chr5_+_71538456 1.285 MAP1B
microtubule-associated protein 1B
chrX_+_21960841 1.234 NM_000444
 PHEX
phosphate regulating endopeptidase homolog, X-linked
chr7_+_94135384 1.039 PEG10
paternally expressed 10
chrX_-_129347101 0.973 NM_178471
 GPR119
G protein-coupled receptor 119
chr6_+_155579788 0.849 NM_001010927
 TIAM2
T-cell lymphoma invasion and metastasis 2
chrX_+_66705407 0.849 NM_001011645
 AR
androgen receptor
chr9_+_129066576 0.818 NM_032293
 GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr20_+_56919233 0.809 GNAS
GNAS complex locus
chrX_+_28515479 0.805 NM_014271
 IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr5_+_140772691 0.781 NM_018913
NM_032090
 PCDHGA10

protocadherin gamma subfamily A, 10

chr10_-_31328426 0.768 NM_001143769
 ZNF438
zinc finger protein 438
chr17_-_46479127 0.751 SPAG9
sperm associated antigen 9
chr19_+_40632456 0.748 NM_005306
 FFAR2
free fatty acid receptor 2
chr5_+_156628929 0.742 NM_014376
 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr12_-_4358968 0.699 NM_020638
 FGF23
fibroblast growth factor 23

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.10 3.92e-04 GO:0007606 sensory perception of chemical stimulus
2.04 5.33e-03 GO:0007608 sensory perception of smell
1.79 5.16e-04 GO:0007600 sensory perception
1.65 7.46e-07 GO:0003008 system process
1.63 1.11e-04 GO:0050877 neurological system process
1.33 5.37e-08 GO:0032501 multicellular organismal process
1.28 9.70e-03 GO:0023052 signaling
1.24 8.73e-05 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.75 5.13e-04 GO:0005882 intermediate filament
2.46 2.87e-03 GO:0045111 intermediate filament cytoskeleton
1.29 9.69e-05 GO:0071944 cell periphery
1.28 2.40e-04 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.14 3.33e-04 GO:0004984 olfactory receptor activity
1.77 1.40e-04 GO:0004930 G-protein coupled receptor activity
1.55 1.07e-03 GO:0004888 transmembrane receptor activity
1.52 8.77e-05 GO:0004872 receptor activity
1.39 3.23e-03 GO:0004871 signal transducer activity
1.39 3.23e-03 GO:0060089 molecular transducer activity