Motif ID: NKX3-1.p2

Z-value: 1.305


Transcription factors associated with NKX3-1.p2:

Gene SymbolEntrez IDGene Name
NKX3-1 4824 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX3-1chr8_-_23596346-0.165.4e-01Click!


Activity profile for motif NKX3-1.p2.

activity profile for motif NKX3-1.p2


Sorted Z-values histogram for motif NKX3-1.p2

Sorted Z-values for motif NKX3-1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_21399132 3.008 NM_002170
IFNA8
interferon, alpha 8
chr3_+_174598937 2.875 NM_014932
NLGN1
neuroligin 1
chr7_+_94377145 2.742 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory (inhibitor) subunit 9A


chr6_+_132000134 2.638 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr22_+_38652555 2.533 GRAP2
GRB2-related adaptor protein 2
chr18_-_29273979 2.370 NM_001105528
C18orf34
chromosome 18 open reading frame 34
chrX_+_99726445 1.864 NM_022144
TNMD
tenomodulin
chr7_+_45899621 1.767


chr3_-_121445831 1.670 NM_001168271
NM_153002
GPR156

G protein-coupled receptor 156

chr4_+_119174947 1.667 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr1_-_3556420 1.525 NM_017818
WDR8
WD repeat domain 8
chr11_-_13474101 1.502 NM_000315
PTH
parathyroid hormone
chr5_+_147238466 1.466 NM_054023
SCGB3A2
secretoglobin, family 3A, member 2
chr11_+_89507465 1.446 NM_005467
NAALAD2
N-acetylated alpha-linked acidic dipeptidase 2
chr9_-_21177529 1.433 NM_021068
IFNA4
interferon, alpha 4
chr3_-_99236520 1.425 NM_001105580
GABRR3
gamma-aminobutyric acid (GABA) receptor, rho 3
chr11_-_100505667 1.419 NM_000926
PGR
progesterone receptor
chr12_-_5925658 1.341 NM_020373
ANO2
anoctamin 2
chr3_+_129124591 1.333 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr1_-_60312013 1.323 NM_152377
C1orf87
chromosome 1 open reading frame 87

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
3.18 3.75e-13 GO:0007608 sensory perception of smell
3.07 1.45e-13 GO:0007606 sensory perception of chemical stimulus
2.16 3.88e-08 GO:0007600 sensory perception
1.69 9.45e-05 GO:0050877 neurological system process
1.65 1.26e-05 GO:0003008 system process
1.29 6.58e-05 GO:0032501 multicellular organismal process
1.22 4.00e-03 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.63 5.15e-08 GO:0005576 extracellular region
1.63 2.95e-02 GO:0005615 extracellular space
1.58 1.06e-02 GO:0044421 extracellular region part
1.39 1.10e-07 GO:0005886 plasma membrane
1.39 1.20e-07 GO:0071944 cell periphery
1.24 9.10e-04 GO:0016021 integral to membrane
1.23 9.93e-04 GO:0031224 intrinsic to membrane
1.22 3.31e-04 GO:0044425 membrane part
1.15 2.40e-02 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
17.26 2.98e-06 GO:0005132 interferon-alpha/beta receptor binding
13.15 4.24e-02 GO:0030021 extracellular matrix structural constituent conferring compression resistance
13.15 4.24e-02 GO:0030345 structural constituent of tooth enamel
3.28 3.49e-14 GO:0004984 olfactory receptor activity
2.38 6.67e-13 GO:0004930 G-protein coupled receptor activity
1.95 3.62e-10 GO:0004888 transmembrane receptor activity
1.74 1.13e-08 GO:0004872 receptor activity
1.53 2.15e-05 GO:0004871 signal transducer activity
1.53 2.15e-05 GO:0060089 molecular transducer activity