Motif ID: NKX6-1,2.p2

Z-value: 0.982


Transcription factors associated with NKX6-1,2.p2:

Gene SymbolEntrez IDGene Name
NKX6-1 4825 NK6 homeobox 1
NKX6-2 84504 NK6 homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX6-2chr10_-_1344494670.107.1e-01Click!
NKX6-1chr4_-_856384100.039.1e-01Click!


Activity profile for motif NKX6-1,2.p2.

activity profile for motif NKX6-1,2.p2


Sorted Z-values histogram for motif NKX6-1,2.p2

Sorted Z-values for motif NKX6-1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX6-1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_52696908 1.820 NM_014620
NM_153693
 HOXC4
HOXC6
homeobox C4
homeobox C6
chr9_-_21375258 1.690 NM_000605
 IFNA2
interferon, alpha 2
chr12_-_28016182 1.342 NM_002820
NM_198965
 PTHLH

parathyroid hormone-like hormone

chr4_-_90978469 1.078 NM_001146055
 SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr12_+_52697160 1.064 HOXC5
HOXC6
homeobox C5
homeobox C6
chr8_-_82769761 1.026 NM_001010893
 SLC10A5
solute carrier family 10 (sodium/bile acid cotransporter family), member 5
chr13_+_23042722 1.006 NM_148957
 TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr3_-_171070314 1.002 NM_024727
 LRRC31
leucine rich repeat containing 31
chr1_-_116184846 0.988 NM_001111061
 NHLH2
nescient helix loop helix 2
chr22_-_34892170 0.919 NM_145641
NM_145642
 APOL3

apolipoprotein L, 3

chr3_-_148607096 0.878 NM_032153
 ZIC4
Zic family member 4
chr20_+_19985289 0.849 NM_001167816
 C20orf26
chromosome 20 open reading frame 26
chr10_-_100985548 0.842 NM_001166244
NM_001166245
NM_001166246
NM_021828
 HPSE2



heparanase 2



chr20_-_19984685 0.819 NM_016652
 CRNKL1
crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr17_-_53849888 0.816 RNF43
ring finger protein 43
chr5_+_140709907 0.813 NM_018922
NM_032095
 PCDHGB1

protocadherin gamma subfamily B, 1

chr6_-_46811388 0.796 NM_001168357
 PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr10_-_14412813 0.754 NM_018027
 FRMD4A
FERM domain containing 4A
chr11_-_7684516 0.750 NM_198185
 OVCH2
ovochymase 2 (gene/pseudogene)
chr18_-_55136673 0.740 NM_181654
 CPLX4
complexin 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
3.37 1.87e-04 GO:0007156 homophilic cell adhesion
1.44 4.47e-02 GO:0003008 system process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.20 7.58e-03 GO:0031224 intrinsic to membrane
1.20 1.07e-02 GO:0016021 integral to membrane
1.16 3.97e-02 GO:0044425 membrane part

Nothing significant found in function category.