Motif ID: ONECUT1,2.p2

Z-value: 1.727


Transcription factors associated with ONECUT1,2.p2:

Gene SymbolEntrez IDGene Name
ONECUT1 3175 one cut homeobox 1
ONECUT2 9480 one cut homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ONECUT1chr15_-_508693790.684.1e-03Click!
ONECUT2chr18_+_532537750.674.3e-03Click!


Activity profile for motif ONECUT1,2.p2.

activity profile for motif ONECUT1,2.p2


Sorted Z-values histogram for motif ONECUT1,2.p2

Sorted Z-values for motif ONECUT1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ONECUT1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_30238961 3.680 NM_033229
TRIM15
tripartite motif containing 15
chr14_-_23117268 3.466 JPH4
junctophilin 4
chr1_-_611896 2.944 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr1_+_357502 2.794 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr12_+_47584159 2.721 NM_033124
CCDC65
coiled-coil domain containing 65
chr5_+_140723939 2.710 NM_018918
NM_032054
PCDHGA5

protocadherin gamma subfamily A, 5

chr5_+_180726874 2.520 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr9_-_21218132 2.409 NM_021268
IFNA17
interferon, alpha 17
chr1_-_150044365 2.313 NM_001004432
LINGO4
leucine rich repeat and Ig domain containing 4
chr5_+_140719773 2.193 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr15_-_100280784 2.146 NM_001004195
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr19_+_61624 2.085 NM_001005240
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr4_+_22303645 2.031 NM_001128432
NM_020973
GBA3

glucosidase, beta, acid 3 (cytosolic)

chr11_-_74478405 1.990 NM_001005285
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr5_-_156705250 1.922 NM_001001343
FNDC9
fibronectin type III domain containing 9
chr5_+_140780797 1.920 PCDHGA11
protocadherin gamma subfamily A, 11
chr7_-_23476497 1.858 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr18_-_28606839 1.857 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr5_+_127012611 1.810 NM_001048252
CTXN3
cortexin 3
chr22_+_22435207 1.735 NM_182520
C22orf15
chromosome 22 open reading frame 15
chr7_+_151284396 1.653 NM_145292
GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr5_+_140780720 1.649 NM_018914
NM_032091
NM_032092
PCDHGA11


protocadherin gamma subfamily A, 11


chrX_-_54841397 1.644 NM_198510
ITIH5L
inter-alpha (globulin) inhibitor H5-like
chr4_-_20594645 1.553 KCNIP4
Kv channel interacting protein 4
chr6_-_138581319 1.537 NM_021635
PBOV1
prostate and breast cancer overexpressed 1
chr18_-_29273979 1.520 NM_001105528
C18orf34
chromosome 18 open reading frame 34
chr15_+_70477707 1.489 NM_001080462
TMEM202
transmembrane protein 202
chr4_-_70861301 1.472 NM_001891
CSN2
casein beta
chr22_-_41366550 1.456 NM_001165877
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr14_-_23117614 1.432 JPH4
junctophilin 4
chr3_-_156876798 1.428 NM_001130960
NM_001130961
PLCH1

phospholipase C, eta 1

chr5_+_357290 1.428 NM_020731
AHRR
aryl-hydrocarbon receptor repressor
chr6_+_28032997 1.427 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr1_-_150328153 1.402 NM_001008536
TCHHL1
trichohyalin-like 1
chrX_-_131401319 1.393 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr9_-_21295311 1.380 NM_002169
IFNA5
interferon, alpha 5
chr16_-_29797172 1.340 SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr7_-_86433139 1.315 NM_152748
KIAA1324L
KIAA1324-like
chr13_+_27264779 1.312 NM_145657
GSX1
GS homeobox 1
chr5_+_140742585 1.304 NM_018920
NM_032087
PCDHGA7

protocadherin gamma subfamily A, 7

chr8_-_107023 1.254 NM_001005504
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr5_-_58918031 1.249 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_94377145 1.246 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory (inhibitor) subunit 9A


chr3_+_101720753 1.243 TMEM45A
transmembrane protein 45A
chr16_+_54782802 1.242 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr16_-_20610078 1.226 NM_052956
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr19_-_5797465 1.219 FUT3
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
chr1_-_146076704 1.211 NM_001101663
NBPF11
NBPF24
neuroblastoma breakpoint family, member 11
neuroblastoma breakpoint family, member 24
chr8_+_69026895 1.199 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr3_+_144165470 1.179 U2SURP
U2 snRNP-associated SURP domain containing
chr18_+_13601664 1.176 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr3_+_185233312 1.170 NM_001163646
HTR3D
5-hydroxytryptamine (serotonin) receptor 3 family member D
chr10_+_68355797 1.170 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr3_+_109498082 1.157 HHLA2
HERV-H LTR-associating 2
chr8_-_15140162 1.138 NM_139167
SGCZ
sarcoglycan, zeta
chr1_-_67366807 1.110 NM_001013674
C1orf141
chromosome 1 open reading frame 141
chr7_+_99263571 1.102 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr11_+_113280727 1.100 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr19_+_3831660 1.086 ATCAY
ataxia, cerebellar, Cayman type
chr19_+_3831675 1.080 ATCAY
ataxia, cerebellar, Cayman type
chr8_+_17440664 1.076 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr11_+_89624017 1.064


chr7_+_94135384 1.052 PEG10
paternally expressed 10
chrX_+_106057984 1.050 CLDN2
claudin 2
chr4_+_157044296 1.045 NM_005651
TDO2
tryptophan 2,3-dioxygenase
chr3_+_12367993 1.042 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr7_+_120490054 1.036 C7orf58
chromosome 7 open reading frame 58
chr3_-_114176401 1.035 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr11_-_128217550 1.027 NM_000220
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr4_-_116254381 1.007 NM_022569
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr14_-_23117833 0.987 NM_001146028
NM_032452
JPH4

junctophilin 4

chr6_-_41823056 0.977 NM_001166424
NM_002630
PGC

progastricsin (pepsinogen C)

chr18_+_27425727 0.976 NM_000371
TTR
transthyretin
chr7_-_121731721 0.964 NM_001024613
NM_001160264
FEZF1

FEZ family zinc finger 1

chr11_+_123625632 0.956 NM_001002905
OR8G1
olfactory receptor, family 8, subfamily G, member 1
chr5_+_57823017 0.956 NM_152687
GAPT
GRB2-binding adaptor protein, transmembrane
chr12_-_4358968 0.950 NM_020638
FGF23
fibroblast growth factor 23
chr1_+_180685878 0.945 NM_001137669
RGSL1
regulator of G-protein signaling like 1
chr10_-_98021144 0.944 NM_001114094
NM_013314
BLNK

B-cell linker

chr11_+_36546138 0.937 NM_000448
RAG1
recombination activating gene 1
chr11_+_60223622 0.936 NM_031457
MS4A8B
membrane-spanning 4-domains, subfamily A, member 8B
chr9_-_21177529 0.927 NM_021068
IFNA4
interferon, alpha 4
chrX_-_106248674 0.921 RBM41
RNA binding motif protein 41
chr1_+_111215343 0.907 NM_001040033
CD53
CD53 molecule
chr18_-_58946858 0.890 BCL2
B-cell CLL/lymphoma 2
chr4_-_145159889 0.875 NM_002100
GYPB
glycophorin B (MNS blood group)
chr8_+_110168828 0.868 NM_003301
TRHR
thyrotropin-releasing hormone receptor
chr9_+_131937163 0.868 GPR107
G protein-coupled receptor 107
chr9_-_115877104 0.867 AMBP
alpha-1-microglobulin/bikunin precursor
chr6_+_32003180 0.845 NM_000063
NM_001145903
C2

complement component 2

chr6_-_167195647 0.838 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chrX_-_10605726 0.836 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr22_+_23921072 0.830 KIAA1671
KIAA1671
chr11_+_125208420 0.828 NM_001144874
PATE4
prostate and testis expressed 4
chr16_-_11274952 0.827 NM_021247
PRM3
protamine 3
chr15_+_60726801 0.825 NM_015059
TLN2
talin 2
chr22_+_21053972 0.821


chr12_+_53178834 0.813 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chrX_+_46825179 0.813 RGN
regucalcin (senescence marker protein-30)
chr12_+_4569504 0.813 NM_003845
DYRK4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr5_-_9683462 0.804 NM_019599
TAS2R1
taste receptor, type 2, member 1
chr5_-_149772563 0.803 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chrX_+_123307812 0.802 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chr19_+_9157269 0.802 NM_175883
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr2_+_132196533 0.802 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr9_-_72926333 0.799 NM_001007471
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chrX_+_99726445 0.799 NM_022144
TNMD
tenomodulin
chr8_-_134156437 0.791 SLA
Src-like-adaptor
chr3_+_63403792 0.786 NM_144642
SYNPR
synaptoporin
chr6_+_146390474 0.784 NM_000838
NM_001114329
GRM1

glutamate receptor, metabotropic 1

chr5_+_140772691 0.778 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr20_-_22514092 0.772 NM_153675
FOXA2
forkhead box A2
chr12_+_9871343 0.771 NM_016523
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr5_-_149772528 0.765


chr1_+_110795271 0.765 NM_032414
PROK1
prokineticin 1
chr3_+_46258875 0.763 NM_001164680
NM_001837
NM_178328
NM_178329
CCR3



chemokine (C-C motif) receptor 3



chr15_-_74139123 0.763 NRG4
neuregulin 4
chr14_+_61532293 0.759 NM_031914
SYT16
synaptotagmin XVI
chr5_-_111340421 0.755 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr5_+_140227951 0.754 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr1_+_117098579 0.745 NM_001767
CD2
CD2 molecule
chr10_+_51219558 0.743 NM_002443
NM_138634
MSMB

microseminoprotein, beta-

chr2_-_163403485 0.738 NM_033272
NM_173162
KCNH7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr4_-_20914626 0.736 NM_147183
KCNIP4
Kv channel interacting protein 4
chr1_+_203804787 0.725 MFSD4
major facilitator superfamily domain containing 4
chr9_+_129066576 0.717 NM_032293
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr5_+_32824701 0.714 NM_024563
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chrX_-_102452461 0.714 NM_001168399
NM_001168400
NM_001168401
NM_032621
BEX2



brain expressed X-linked 2



chr6_+_100161370 0.707 NM_021620
PRDM13
PR domain containing 13
chr11_+_122214415 0.706 NM_019604
CRTAM
cytotoxic and regulatory T cell molecule
chr2_-_21106291 0.704 APOB
apolipoprotein B (including Ag(x) antigen)
chr12_-_10846435 0.704 NM_023919
TAS2R7
taste receptor, type 2, member 7
chrX_-_133620103 0.701 NM_021796
PLAC1
placenta-specific 1
chr4_+_47403107 0.700


chr3_-_121445831 0.698 NM_001168271
NM_153002
GPR156

G protein-coupled receptor 156

chrX_+_47114925 0.692 NM_003446
ZNF157
zinc finger protein 157
chr1_+_144004589 0.691 NM_001039703
NBPF10
NBPF8
neuroblastoma breakpoint family, member 10
neuroblastoma breakpoint family, member 8
chr7_-_142769818 0.689 NM_001031690
FAM131B
family with sequence similarity 131, member B
chr4_-_100431093 0.688 NM_000667
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr21_+_30724442 0.684 NM_181600
KRTAP13-4
keratin associated protein 13-4
chr10_+_102722275 0.673 NM_017893
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chrX_-_106248706 0.671 NM_001171080
NM_018301
RBM41

RNA binding motif protein 41

chr8_-_124818754 0.668 NM_001003954
NM_004306
ANXA13

annexin A13

chr6_+_116889248 0.668 NM_001010919
FAM26F
family with sequence similarity 26, member F
chr19_-_55539769 0.667 NAPSB
napsin B aspartic peptidase pseudogene
chrX_-_24600661 0.661 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr1_+_144374513 0.659 RNF115
ring finger protein 115
chr9_+_123123364 0.655 GSN
gelsolin
chr15_+_64787983 0.654 NM_001142861
SMAD6
SMAD family member 6
chr17_+_28342994 0.652 NM_173847
SPACA3
sperm acrosome associated 3
chr6_-_46401174 0.651 RCAN2
regulator of calcineurin 2
chr10_+_46503539 0.650 NM_005972
PPYR1
pancreatic polypeptide receptor 1
chr3_+_123385219 0.649 NM_000388
CASR
calcium-sensing receptor
chr12_-_11230809 0.646 NM_181429
TAS2R42
taste receptor, type 2, member 42
chr11_-_16953135 0.646 RPL36A
ribosomal protein L36a
chr11_+_22646229 0.643 NM_177553
GAS2
growth arrest-specific 2
chr16_-_70591377 0.642 NM_181536
PKD1L3
polycystic kidney disease 1-like 3
chr5_-_149772469 0.640 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr1_-_177378801 0.638 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr5_+_140751666 0.638 NM_014004
NM_032088
PCDHGA8

protocadherin gamma subfamily A, 8

chr4_+_37638450 0.635 NM_006607
PTTG2
pituitary tumor-transforming 2
chr3_-_168854395 0.633 WDR49
WD repeat domain 49
chr7_+_128099581 0.630 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chr1_-_144779601 0.629 NM_001101663
NBPF11
NBPF24
neuroblastoma breakpoint family, member 11
neuroblastoma breakpoint family, member 24
chr6_-_64087806 0.628 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr8_-_27997306 0.628 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr15_+_74139378 0.627 C15orf27
chromosome 15 open reading frame 27
chr3_-_42789738 0.625 NM_144719
CCDC13
coiled-coil domain containing 13
chr7_+_128795178 0.625 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr8_+_118216517 0.624 NM_001172814
NM_173851
SLC30A8

solute carrier family 30 (zinc transporter), member 8

chr9_-_69468634 0.624 NM_001126334
FOXD4L5
forkhead box D4-like 5
chr6_+_53043729 0.618 NM_012347
FBXO9
F-box protein 9
chr19_+_46762872 0.615 CEACAM21
carcinoembryonic antigen-related cell adhesion molecule 21
chr4_+_3285671 0.609 NM_002926
NM_198229
RGS12

regulator of G-protein signaling 12

chr7_+_128795280 0.600 AHCYL2
adenosylhomocysteinase-like 2
chr1_+_148747110 0.599 NM_004425
NM_022664
ECM1

extracellular matrix protein 1

chr12_-_89976261 0.598 NM_007035
KERA
keratocan
chr3_+_2117246 0.595 NM_175607
CNTN4
contactin 4
chr5_+_176449156 0.595 NM_022963
FGFR4
fibroblast growth factor receptor 4
chr11_-_129803515 0.594 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr22_-_38619739 0.593 NM_152512
ENTHD1
ENTH domain containing 1
chr18_-_3864252 0.592 DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr2_-_219906142 0.589 NM_001007089
RESP18
regulated endocrine-specific protein 18 homolog (rat)
chr6_-_50124322 0.589 NM_001037498
DEFB112
defensin, beta 112
chr3_-_148607096 0.588 NM_032153
ZIC4
Zic family member 4
chr14_+_28311740 0.586 C14orf23
chromosome 14 open reading frame 23
chr14_-_20098929 0.584 NM_001001673
NM_001110356
NM_001110357
NM_001110358
NM_001110359
NM_001110360
NM_001110361
RNASE9






ribonuclease, RNase A family, 9 (non-active)






chr7_-_105106844 0.582 NM_138495
ATXN7L1
ataxin 7-like 1
chrX_+_41433169 0.581 NM_001097579
NM_005300
GPR34

G protein-coupled receptor 34

chr3_-_139333813 0.580 NM_016161
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr14_-_20179689 0.579 NM_001001968
OR6S1
olfactory receptor, family 6, subfamily S, member 1
chr22_-_43987978 0.575 KIAA0930
KIAA0930
chr7_-_94791763 0.572 NM_000446
PON1
paraoxonase 1
chr15_+_74139325 0.571 NM_152335
C15orf27
chromosome 15 open reading frame 27
chr14_-_60185659 0.571 NM_005982
SIX1
SIX homeobox 1
chr10_-_72215116 0.570 NM_152710
C10orf27
chromosome 10 open reading frame 27
chr12_-_242255 0.568 NM_001190997
NM_016615
SLC6A13

solute carrier family 6 (neurotransmitter transporter, GABA), member 13

chr9_+_86474393 0.566 NM_001018065
NM_001018066
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr10_+_134751398 0.565 NM_001083909
GPR123
G protein-coupled receptor 123
chr5_+_140166842 0.565 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.11 5.47e-16 GO:0007606 sensory perception of chemical stimulus
3.16 1.04e-14 GO:0007608 sensory perception of smell
2.16 2.30e-09 GO:0007600 sensory perception
1.34 1.09e-07 GO:0032501 multicellular organismal process
1.78 2.36e-07 GO:0050877 neurological system process
1.67 3.43e-07 GO:0003008 system process
1.24 1.22e-04 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.44 5.44e-11 GO:0005886 plasma membrane
1.42 2.18e-10 GO:0071944 cell periphery
1.25 1.43e-06 GO:0044425 membrane part
1.26 1.26e-05 GO:0031224 intrinsic to membrane
1.25 5.91e-05 GO:0016021 integral to membrane
1.18 1.07e-04 GO:0016020 membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.46 2.66e-16 GO:0004930 G-protein coupled receptor activity
3.26 7.23e-16 GO:0004984 olfactory receptor activity
1.87 1.87e-13 GO:0004872 receptor activity
2.01 6.15e-13 GO:0004888 transmembrane receptor activity
1.72 7.99e-12 GO:0004871 signal transducer activity
1.72 7.99e-12 GO:0060089 molecular transducer activity