Motif ID: PATZ1.p2

Z-value: 1.185


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PATZ1chr22_-_300717610.477.0e-02Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_132961723 2.579 AIF1L
allograft inflammatory factor 1-like
chr22_-_19122107 1.988 NM_153334
NM_182895
SCARF2

scavenger receptor class F, member 2

chr9_+_132961683 1.929 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr22_-_19122047 1.730 SCARF2
scavenger receptor class F, member 2
chr2_+_10101081 1.432 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr8_+_1699418 1.337 CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr1_+_181259317 1.317


chr12_-_105165805 1.242 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr19_-_59676153 1.218 NM_145057
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr8_+_22513043 1.201 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr19_-_51168396 1.149 NM_002516
NOVA2
neuro-oncological ventral antigen 2
chr7_-_107883929 1.091 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr20_-_30534848 1.022 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr4_+_3264509 0.973 RGS12
regulator of G-protein signaling 12
chr15_-_76890626 0.940 NM_014272
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr22_+_18081968 0.903 NM_002688
SEPT5
septin 5
chr7_-_28186671 0.886 JAZF1
JAZF zinc finger 1
chr17_-_74433048 0.874 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr1_-_223907283 0.858 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr7_-_102044419 0.832 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr17_-_74432800 0.820 TIMP2
TIMP metallopeptidase inhibitor 2
chr6_+_37245860 0.808 NM_002648
PIM1
pim-1 oncogene
chrX_-_1291526 0.786 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr1_-_1465602 0.782 NM_001114748
C1orf70
chromosome 1 open reading frame 70
chr1_-_32574185 0.777 NM_023009
MARCKSL1
MARCKS-like 1
chr4_+_145786622 0.761 NM_022475
HHIP
hedgehog interacting protein
chr6_+_11646472 0.761 NM_001100829
TMEM170B
transmembrane protein 170B
chr8_+_1699276 0.758 NM_018941
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr12_-_47468985 0.755 NM_020983
ADCY6
adenylate cyclase 6
chr22_+_21742727 0.753 GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr2_+_54536780 0.748 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr17_-_74432671 0.748 TIMP2
TIMP metallopeptidase inhibitor 2
chr12_+_50271283 0.746 NM_014191
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr17_+_77582774 0.724 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr2_+_25118417 0.723 NM_014971
EFR3B
EFR3 homolog B (S. cerevisiae)
chr6_-_42527760 0.697 NM_033502
TRERF1
transcriptional regulating factor 1
chr1_+_113734997 0.684 NM_001142782
NM_152900
MAGI3

membrane associated guanylate kinase, WW and PDZ domain containing 3

chr22_-_17659183 0.680 NM_001835
NM_007098
CLTCL1

clathrin, heavy chain-like 1

chr8_+_142207866 0.672 NM_014957
DENND3
DENN/MADD domain containing 3
chr21_+_46226072 0.659 NM_001848
COL6A1
collagen, type VI, alpha 1
chr12_+_69046241 0.656 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr1_-_6480035 0.649 PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr7_-_94123308 0.645 SGCE
sarcoglycan, epsilon
chr7_-_27120015 0.639 HOXA3
homeobox A3
chr22_-_21231421 0.635 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr1_+_181258952 0.631 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chrX_-_19815586 0.629 NM_031892
SH3KBP1
SH3-domain kinase binding protein 1
chr1_+_199884072 0.627 NM_020443
NAV1
neuron navigator 1
chrX_+_152413540 0.622 NM_001711
BGN
biglycan
chr7_-_158073121 0.620 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr6_+_43151922 0.616 NM_002821
NM_152880
NM_152881
NM_152882
PTK7



PTK7 protein tyrosine kinase 7



chr1_+_6767968 0.599 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr8_+_146248634 0.598 C8orf33
chromosome 8 open reading frame 33
chr22_+_40107878 0.597 NM_003216
TEF
thyrotrophic embryonic factor
chr7_+_73080362 0.593 NM_000501
NM_001081752
NM_001081753
NM_001081754
NM_001081755
ELN




elastin




chr17_+_4683280 0.580 NM_001024937
NM_015716
NM_153827
NM_170663
MINK1



misshapen-like kinase 1



chr6_+_44346457 0.579 NM_001137560
TMEM151B
transmembrane protein 151B
chr6_-_31977747 0.577 NM_181842
ZBTB12
zinc finger and BTB domain containing 12
chr8_+_144706699 0.576 NM_001166237
GSDMD
gasdermin D
chr9_-_131845277 0.573 NM_015033
FNBP1
formin binding protein 1
chr19_+_47480445 0.573 NM_015125
CIC
capicua homolog (Drosophila)
chr7_-_102044374 0.572 RASA4
RAS p21 protein activator 4
chr7_-_28186867 0.568 NM_175061
JAZF1
JAZF zinc finger 1
chr7_+_73080422 0.565 ELN
elastin
chr19_+_40958206 0.562 NM_001172630
NM_052948
ARHGAP33

Rho GTPase activating protein 33

chr7_-_526005 0.561 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr19_+_14405216 0.560 PKN1
protein kinase N1
chr9_-_129557373 0.555 NM_001142534
NM_001142533
SH2D3C

SH2 domain containing 3C

chr12_-_103055924 0.551 NM_006166
NFYB
nuclear transcription factor Y, beta
chr19_-_55914837 0.550


chr11_+_65049152 0.549 SCYL1
SCY1-like 1 (S. cerevisiae)
chr20_-_30535045 0.548 C20orf112
chromosome 20 open reading frame 112
chr7_+_73080404 0.548 ELN
elastin
chr16_+_29730909 0.546 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr1_+_199884152 0.545 NAV1
neuron navigator 1
chr7_-_143622188 0.544 ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr9_-_131845077 0.543 FNBP1
formin binding protein 1
chr7_+_143683365 0.542 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr1_-_6480058 0.542 NM_001042663
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr20_-_47618059 0.542 NM_000961
PTGIS
prostaglandin I2 (prostacyclin) synthase
chr2_+_85834111 0.538 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr8_+_31010319 0.538 NM_000553
WRN
Werner syndrome, RecQ helicase-like
chr7_-_94123413 0.537 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr9_-_122679387 0.537 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr22_-_49042065 0.535 NM_002969
MAPK12
mitogen-activated protein kinase 12
chr7_+_73080387 0.531 ELN
elastin
chr1_-_202387532 0.526 ETNK2
ethanolamine kinase 2
chr11_+_65049102 0.526 NM_001048218
NM_020680
SCYL1

SCY1-like 1 (S. cerevisiae)

chr7_+_90063543 0.525 CDK14
cyclin-dependent kinase 14
chr15_-_62854749 0.522 NM_194272
RBPMS2
RNA binding protein with multiple splicing 2
chr10_-_49483002 0.521 NM_021226
ARHGAP22
Rho GTPase activating protein 22
chr2_+_54537842 0.521 SPTBN1
spectrin, beta, non-erythrocytic 1
chr17_-_41018291 0.520


chr5_-_1165106 0.519 NM_006598
SLC12A7
solute carrier family 12 (potassium/chloride transporters), member 7
chr17_-_17667580 0.515 SREBF1
sterol regulatory element binding transcription factor 1
chr7_-_94123362 0.515 SGCE
sarcoglycan, epsilon
chr20_-_62181231 0.514 NM_005873
RGS19
regulator of G-protein signaling 19
chr6_+_31190505 0.510 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr11_+_63829616 0.507 NM_004451
ESRRA
estrogen-related receptor alpha
chr6_-_112301123 0.504 NM_002037
FYN
FYN oncogene related to SRC, FGR, YES
chr22_+_19649417 0.502 NM_001018060
NM_144704
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr7_+_44110470 0.502 NM_001129
AEBP1
AE binding protein 1
chr19_-_8581559 0.501 NM_030957
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr15_-_53822468 0.501 NM_173814
PRTG
protogenin
chr17_+_1906262 0.496 NM_001098202
HIC1
hypermethylated in cancer 1
chr7_-_143622233 0.495 ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr3_+_37878647 0.489 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chrX_-_19815526 0.488 SH3KBP1
SH3-domain kinase binding protein 1
chr7_-_27136876 0.487 NM_002141
HOXA4
homeobox A4
chr7_+_44110527 0.486 AEBP1
AE binding protein 1
chr16_+_29731058 0.482 PRRT2
proline-rich transmembrane protein 2
chr1_+_200124412 0.479 NM_198149
SHISA4
shisa homolog 4 (Xenopus laevis)
chr7_+_128257698 0.476 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr19_+_40213431 0.475 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr12_+_50104859 0.474 NM_001039960
NM_004858
SLC4A8

solute carrier family 4, sodium bicarbonate cotransporter, member 8

chr5_+_92946348 0.472 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr9_+_127549437 0.467 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr2_+_64534774 0.466 NM_014181
HSPC159
galectin-related protein
chr7_-_143523582 0.465 NM_001003702
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chrX_+_111212908 0.461 NM_001004308
ZCCHC16
zinc finger, CCHC domain containing 16
chr17_+_78630793 0.461 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr15_-_19221463 0.459


chr19_-_7896974 0.457 NM_206833
CTXN1
cortexin 1
chr2_+_173000590 0.456 ITGA6
integrin, alpha 6
chr22_-_35835548 0.456 TMPRSS6
transmembrane protease, serine 6
chr22_+_19649460 0.455 AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr1_+_3531410 0.455 NM_182752
TPRG1L
tumor protein p63 regulated 1-like
chr9_+_135314907 0.453 NM_001135775
NM_017586
C9orf7

chromosome 9 open reading frame 7

chrX_-_152749190 0.453 NM_032512
PDZD4
PDZ domain containing 4
chr7_+_73136254 0.452 LIMK1
LIM domain kinase 1
chr14_-_64508547 0.449 NM_198686
RAB15
RAB15, member RAS onocogene family
chr20_-_62181588 0.448 NM_001039467
RGS19
regulator of G-protein signaling 19
chr7_+_101861007 0.447 ORAI2
ORAI calcium release-activated calcium modulator 2
chr17_+_71097147 0.447 MYO15B
myosin XVB pseudogene
chr16_+_84202515 0.444 NM_001134473
KIAA0182
KIAA0182
chr21_-_44485269 0.443 ICOSLG
inducible T-cell co-stimulator ligand
chr3_-_38666122 0.440 NM_000335
NM_001099404
NM_001099405
NM_198056
NM_001160160
NM_001160161
SCN5A





sodium channel, voltage-gated, type V, alpha subunit





chr7_-_127833231 0.438 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr22_-_19716837 0.437 NM_004173
SLC7A4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
chr6_+_41714171 0.437 NM_005586
MDFI
MyoD family inhibitor
chr17_-_76622967 0.436 FLJ90757
hypothetical LOC440465
chr9_+_132874324 0.434 NM_006059
LAMC3
laminin, gamma 3
chr22_-_17303654 0.433 PRODH
proline dehydrogenase (oxidase) 1
chr19_+_15079141 0.429 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr4_-_83702123 0.427 NM_001080506
TMEM150C
transmembrane protein 150C
chr15_-_58671929 0.427 NM_134262
RORA
RAR-related orphan receptor A
chr6_-_33393471 0.426 NM_005453
ZBTB22
zinc finger and BTB domain containing 22
chr7_-_142816019 0.417 NM_005232
EPHA1
EPH receptor A1
chr19_-_15421761 0.417 NM_021241
WIZ
widely interspaced zinc finger motifs
chr16_+_6009095 0.412 NM_001142333
NM_018723
RBFOX1

RNA binding protein, fox-1 homolog (C. elegans) 1

chr3_+_112273464 0.412 NM_015480
PVRL3
poliovirus receptor-related 3
chr17_+_26446082 0.411 NF1
neurofibromin 1
chr2_+_10101822 0.409 NM_001177718
KLF11
Kruppel-like factor 11
chr3_-_14964403 0.408


chr19_-_56178882 0.405 NM_139277
NM_005046
KLK7

kallikrein-related peptidase 7

chr22_-_17546234 0.405 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr10_-_105604942 0.405 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr9_+_139091759 0.404 NM_207309
UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr22_+_21742364 0.404 NM_002073
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr5_+_52320660 0.402 NM_002203
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr6_-_143307976 0.401 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr16_+_80036275 0.400 NM_198390
CMIP
c-Maf-inducing protein
chr17_+_63252704 0.399 BPTF
bromodomain PHD finger transcription factor
chrX_+_152413646 0.399 BGN
biglycan
chr1_+_9275542 0.396 SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr9_-_124030770 0.395 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr2_-_179837490 0.395 NM_178123
SESTD1
SEC14 and spectrin domains 1
chr8_+_136539290 0.392 KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr18_+_75256954 0.392 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr15_+_71763773 0.388 CD276
CD276 molecule
chr7_+_101860958 0.387 NM_001126340
NM_032831
ORAI2

ORAI calcium release-activated calcium modulator 2

chr6_+_17501589 0.385 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr15_+_71763830 0.384 CD276
CD276 molecule
chr22_-_17546296 0.383 NM_005984
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr15_+_24799174 0.381 NM_033223
GABRG3
gamma-aminobutyric acid (GABA) A receptor, gamma 3
chr11_-_9069668 0.380 NM_001170690
NM_020974
SCUBE2

signal peptide, CUB domain, EGF-like 2

chr22_-_18384251 0.377 NM_001670
ARVCF
armadillo repeat gene deleted in velocardiofacial syndrome
chr5_-_171814026 0.377 NM_001017995
SH3PXD2B
SH3 and PX domains 2B
chr5_-_38592439 0.376 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr9_+_127550298 0.376 NM_001134778
PBX3
pre-B-cell leukemia homeobox 3
chrX_-_19815370 0.376 SH3KBP1
SH3-domain kinase binding protein 1
chrX_+_153318452 0.375 NM_001493
GDI1
GDP dissociation inhibitor 1
chr19_+_10404110 0.375 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr19_-_36531958 0.375 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr21_+_42946719 0.372 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr10_-_75241347 0.372 NDST2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr1_-_31485320 0.368 NM_024522
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr8_-_38444675 0.367 FGFR1
fibroblast growth factor receptor 1
chr10_-_25281510 0.366 NM_020200
PRTFDC1
phosphoribosyl transferase domain containing 1
chr19_+_14405100 0.366 NM_002741
PKN1
protein kinase N1
chr20_-_55274497 0.366 BMP7
bone morphogenetic protein 7
chr2_+_42128521 0.366 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr9_+_139092016 0.366 UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr1_-_3437834 0.365 MEGF6
multiple EGF-like-domains 6
chr14_-_94855848 0.365 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr5_-_172689111 0.365 NM_003714
STC2
stanniocalcin 2
chr19_-_13977875 0.365 RFX1
regulatory factor X, 1 (influences HLA class II expression)
chr22_-_17545872 0.364 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr19_-_4408789 0.363 NM_025241
UBXN6
UBX domain protein 6
chr8_+_37773991 0.363 GPR124
G protein-coupled receptor 124

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.14 1.60e-21 GO:0044237 cellular metabolic process
1.17 2.00e-20 GO:0044260 cellular macromolecule metabolic process
1.07 2.08e-20 GO:0009987 cellular process
1.10 1.51e-14 GO:0008152 metabolic process
1.11 2.68e-14 GO:0044238 primary metabolic process
1.13 1.49e-13 GO:0043170 macromolecule metabolic process
1.15 1.11e-10 GO:0016043 cellular component organization
1.09 1.20e-10 GO:0050794 regulation of cellular process
1.17 2.37e-10 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15 2.72e-10 GO:0071840 cellular component organization or biogenesis
1.15 3.25e-10 GO:0034641 cellular nitrogen compound metabolic process
1.18 5.57e-10 GO:0044267 cellular protein metabolic process
1.15 1.77e-09 GO:0006807 nitrogen compound metabolic process
1.08 2.61e-09 GO:0050789 regulation of biological process
1.14 8.79e-09 GO:0031323 regulation of cellular metabolic process
1.08 1.26e-08 GO:0065007 biological regulation
1.19 3.13e-08 GO:0006464 protein modification process
1.15 6.28e-08 GO:0048518 positive regulation of biological process
1.16 1.49e-07 GO:0048522 positive regulation of cellular process
1.18 2.52e-07 GO:0043412 macromolecule modification
1.15 2.87e-07 GO:0071842 cellular component organization at cellular level
1.13 3.69e-07 GO:0080090 regulation of primary metabolic process
1.13 4.11e-07 GO:0060255 regulation of macromolecule metabolic process
1.14 7.53e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.16 8.38e-07 GO:0090304 nucleic acid metabolic process
1.34 2.01e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.11 2.25e-06 GO:0019222 regulation of metabolic process
1.19 2.50e-06 GO:0006996 organelle organization
1.12 5.81e-06 GO:0051179 localization
1.16 6.42e-06 GO:0048523 negative regulation of cellular process
1.26 6.81e-06 GO:0051128 regulation of cellular component organization
1.13 1.01e-05 GO:0019538 protein metabolic process
1.38 1.96e-05 GO:0044419 interspecies interaction between organisms
1.20 1.97e-05 GO:0033036 macromolecule localization
1.38 2.64e-05 GO:0016568 chromatin modification
1.14 2.91e-05 GO:0044249 cellular biosynthetic process
1.13 7.07e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.14 8.13e-05 GO:0048519 negative regulation of biological process
1.16 1.01e-04 GO:0016070 RNA metabolic process
1.13 1.27e-04 GO:0009058 biosynthetic process
1.50 1.32e-04 GO:0016569 covalent chromatin modification
1.27 1.45e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.13 1.53e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 1.58e-04 GO:0006793 phosphorus metabolic process
1.21 1.58e-04 GO:0006796 phosphate metabolic process
1.25 1.65e-04 GO:0016192 vesicle-mediated transport
1.12 1.81e-04 GO:0051234 establishment of localization
1.50 1.95e-04 GO:0016570 histone modification
1.34 2.04e-04 GO:0007264 small GTPase mediated signal transduction
1.12 2.38e-04 GO:0006810 transport
1.15 2.60e-04 GO:0010467 gene expression
1.16 3.31e-04 GO:0034645 cellular macromolecule biosynthetic process
1.18 6.28e-04 GO:0051641 cellular localization
1.12 6.49e-04 GO:0010468 regulation of gene expression
1.22 7.79e-04 GO:0006351 transcription, DNA-dependent
1.15 7.97e-04 GO:0009059 macromolecule biosynthetic process
1.26 8.37e-04 GO:0051276 chromosome organization
1.17 1.01e-03 GO:0009966 regulation of signal transduction
1.15 1.22e-03 GO:0023051 regulation of signaling
1.20 1.37e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.17 1.46e-03 GO:0035556 intracellular signal transduction
1.18 1.53e-03 GO:0031325 positive regulation of cellular metabolic process
1.12 1.68e-03 GO:0031326 regulation of cellular biosynthetic process
1.12 1.69e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.12 1.82e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.13 1.97e-03 GO:0051252 regulation of RNA metabolic process
1.11 1.99e-03 GO:0009889 regulation of biosynthetic process
1.21 2.46e-03 GO:0016310 phosphorylation
1.36 2.49e-03 GO:0051130 positive regulation of cellular component organization
1.23 3.30e-03 GO:0006468 protein phosphorylation
1.42 3.64e-03 GO:0001701 in utero embryonic development
1.09 3.86e-03 GO:0023052 signaling
1.18 4.59e-03 GO:0022607 cellular component assembly
1.18 5.08e-03 GO:0008104 protein localization
1.17 5.89e-03 GO:0009893 positive regulation of metabolic process
1.08 6.38e-03 GO:0051716 cellular response to stimulus
1.19 7.13e-03 GO:0009892 negative regulation of metabolic process
1.39 7.17e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.18 8.27e-03 GO:0032268 regulation of cellular protein metabolic process
1.18 8.55e-03 GO:0051246 regulation of protein metabolic process
1.17 8.90e-03 GO:0051649 establishment of localization in cell
1.17 1.07e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.26 1.49e-02 GO:0006325 chromatin organization
1.23 1.93e-02 GO:0051726 regulation of cell cycle
1.38 2.00e-02 GO:0045786 negative regulation of cell cycle
1.19 2.16e-02 GO:0045184 establishment of protein localization
1.09 2.25e-02 GO:0007165 signal transduction
1.12 2.49e-02 GO:0006355 regulation of transcription, DNA-dependent
1.20 2.78e-02 GO:0031399 regulation of protein modification process
1.20 2.88e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.19 2.96e-02 GO:0031324 negative regulation of cellular metabolic process
1.26 3.18e-02 GO:0045859 regulation of protein kinase activity
1.20 3.39e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29 3.45e-02 GO:0043009 chordate embryonic development
1.16 3.50e-02 GO:0044085 cellular component biogenesis
1.18 3.74e-02 GO:0032774 RNA biosynthetic process
1.20 4.13e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.19 4.23e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.19 4.67e-02 GO:0033554 cellular response to stress
1.18 4.86e-02 GO:0010605 negative regulation of macromolecule metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 5.82e-40 GO:0044424 intracellular part
1.09 7.32e-39 GO:0005622 intracellular
1.12 3.58e-34 GO:0043227 membrane-bounded organelle
1.12 8.79e-34 GO:0043231 intracellular membrane-bounded organelle
1.10 4.81e-30 GO:0043226 organelle
1.10 1.74e-29 GO:0043229 intracellular organelle
1.12 7.05e-29 GO:0005737 cytoplasm
1.16 2.96e-27 GO:0005634 nucleus
1.23 1.33e-16 GO:0044428 nuclear part
1.12 1.25e-15 GO:0044444 cytoplasmic part
1.22 6.38e-14 GO:0005829 cytosol
1.22 3.47e-12 GO:0031981 nuclear lumen
1.11 4.72e-11 GO:0044446 intracellular organelle part
1.18 8.46e-11 GO:0043233 organelle lumen
1.18 9.09e-11 GO:0070013 intracellular organelle lumen
1.10 1.02e-10 GO:0044422 organelle part
1.17 5.77e-10 GO:0031974 membrane-enclosed lumen
1.24 6.26e-10 GO:0005654 nucleoplasm
1.02 2.28e-06 GO:0044464 cell part
1.02 2.54e-06 GO:0005623 cell
1.16 4.15e-05 GO:0012505 endomembrane system
1.22 5.44e-04 GO:0044451 nucleoplasm part
1.18 2.24e-02 GO:0031988 membrane-bounded vesicle
1.10 3.41e-02 GO:0031090 organelle membrane
1.18 4.49e-02 GO:0016023 cytoplasmic membrane-bounded vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 1.28e-33 GO:0005515 protein binding
1.07 7.03e-27 GO:0005488 binding
1.25 1.53e-05 GO:0016301 kinase activity
1.25 2.24e-05 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.22 2.75e-05 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.13 4.55e-05 GO:0000166 nucleotide binding
1.08 1.10e-04 GO:0003824 catalytic activity
1.26 1.26e-04 GO:0004672 protein kinase activity
1.31 1.29e-04 GO:0004674 protein serine/threonine kinase activity
1.10 6.56e-04 GO:0003676 nucleic acid binding
1.35 6.72e-04 GO:0008134 transcription factor binding
1.22 1.04e-03 GO:0019899 enzyme binding
1.14 1.05e-03 GO:0016740 transferase activity
1.18 2.69e-03 GO:0030528 transcription regulator activity
1.13 4.47e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.65 4.85e-03 GO:0042393 histone binding
1.12 5.79e-03 GO:0017076 purine nucleotide binding
1.12 6.70e-03 GO:0032553 ribonucleotide binding
1.12 6.70e-03 GO:0032555 purine ribonucleotide binding
1.23 1.04e-02 GO:0008092 cytoskeletal protein binding
1.11 1.13e-02 GO:0003677 DNA binding
1.25 1.97e-02 GO:0019904 protein domain specific binding
1.18 2.63e-02 GO:0003723 RNA binding
1.37 3.34e-02 GO:0003682 chromatin binding
1.39 3.83e-02 GO:0000287 magnesium ion binding
1.19 4.37e-02 GO:0043565 sequence-specific DNA binding