Motif ID: PAX2.p2

Z-value: 1.853


Transcription factors associated with PAX2.p2:

Gene SymbolEntrez IDGene Name
PAX2 5076 paired box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX2chr10_+_102495327-0.194.9e-01Click!


Activity profile for motif PAX2.p2.

activity profile for motif PAX2.p2


Sorted Z-values histogram for motif PAX2.p2

Sorted Z-values for motif PAX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_45542653 2.543 NM_001169106
NM_001169107
NM_015262
 FAM21C


FAM21A
family with sequence similarity 21, member C


family with sequence similarity 21, member A
chr6_-_84994032 2.295 NM_014895
 KIAA1009
KIAA1009
chr11_+_66915997 1.902 NM_004584
 RAD9A
RAD9 homolog A (S. pombe)
chr20_+_46971618 1.691 NM_006420
 ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr14_+_76634323 1.661 NM_033426
 KIAA1737
KIAA1737
chr2_-_176575171 1.616 NM_030650
 KIAA1715
KIAA1715
chr10_-_45410197 1.580 NM_001002265
NM_145021
 MARCH8

membrane-associated ring finger (C3HC4) 8

chr6_+_127629677 1.551 NM_030963
 RNF146
ring finger protein 146
chr11_-_85457469 1.497 PICALM
phosphatidylinositol binding clathrin assembly protein
chr2_+_42249896 1.481 NM_001145076
NM_019063
 EML4

echinoderm microtubule associated protein like 4

chr17_+_25467948 1.450 NM_032141
 CCDC55
coiled-coil domain containing 55
chr6_+_160310118 1.418 NM_000876
 IGF2R
insulin-like growth factor 2 receptor
chr2_+_177785667 1.386 NM_194247
 HNRNPA3P1
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
heterogeneous nuclear ribonucleoprotein A3
chr20_+_37024383 1.319 NM_001190809
NM_021931
 DHX35

DEAH (Asp-Glu-Ala-His) box polypeptide 35

chr20_+_2744947 1.257 NM_001167670
 LOC100288797
hypothetical protein LOC100288797
chr17_-_39556483 1.257 HDAC5
histone deacetylase 5
chr2_+_62787534 1.168 NM_001142614
 EHBP1
EH domain binding protein 1
chr22_+_38903825 1.158 NM_001162501
NM_015088
 TNRC6B

trinucleotide repeat containing 6B

chr2_+_46779827 1.143 NM_144949
 SOCS5
suppressor of cytokine signaling 5
chr17_-_39556535 1.139 NM_001015053
NM_005474
 HDAC5

histone deacetylase 5


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 30 entries
enrichment   p-value GO term description
1.76 3.63e-02 GO:0033365 protein localization to organelle
1.69 7.63e-03 GO:0048285 organelle fission
1.65 3.30e-02 GO:0000280 nuclear division
1.65 3.30e-02 GO:0007067 mitosis
1.62 9.67e-03 GO:0016568 chromatin modification
1.62 4.93e-02 GO:0000087 M phase of mitotic cell cycle
1.53 5.41e-03 GO:0034613 cellular protein localization
1.52 7.48e-03 GO:0070727 cellular macromolecule localization
1.49 9.68e-05 GO:0046907 intracellular transport
1.47 4.76e-02 GO:0016071 mRNA metabolic process
1.36 6.41e-03 GO:0007049 cell cycle
1.35 8.33e-07 GO:0010467 gene expression
1.34 1.14e-05 GO:0016070 RNA metabolic process
1.33 1.92e-02 GO:0051649 establishment of localization in cell
1.32 1.17e-06 GO:0090304 nucleic acid metabolic process
1.31 1.27e-02 GO:0033036 macromolecule localization
1.31 1.53e-02 GO:0051641 cellular localization
1.30 1.90e-03 GO:0006996 organelle organization
1.29 1.42e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 6.41e-07 GO:0034641 cellular nitrogen compound metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
1.86 1.72e-02 GO:0005769 early endosome
1.47 1.57e-02 GO:0044427 chromosomal part
1.41 2.55e-02 GO:0005694 chromosome
1.32 4.55e-04 GO:0005654 nucleoplasm
1.27 2.71e-05 GO:0044428 nuclear part
1.26 5.83e-04 GO:0031981 nuclear lumen
1.26 2.08e-02 GO:0005739 mitochondrion
1.24 3.03e-04 GO:0031974 membrane-enclosed lumen
1.24 4.09e-04 GO:0043233 organelle lumen
1.23 5.14e-07 GO:0032991 macromolecular complex
1.23 1.27e-03 GO:0070013 intracellular organelle lumen
1.23 2.98e-03 GO:0005829 cytosol
1.22 4.08e-13 GO:0005634 nucleus
1.22 5.18e-05 GO:0043234 protein complex
1.19 9.08e-10 GO:0044422 organelle part
1.19 1.54e-09 GO:0044446 intracellular organelle part
1.18 7.60e-03 GO:0043228 non-membrane-bounded organelle
1.18 7.60e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.17 1.40e-17 GO:0043231 intracellular membrane-bounded organelle
1.17 2.44e-17 GO:0043227 membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.76 4.92e-03 GO:0003713 transcription coactivator activity
1.69 1.46e-02 GO:0019787 small conjugating protein ligase activity
1.68 3.66e-02 GO:0004842 ubiquitin-protein ligase activity
1.62 7.94e-04 GO:0003712 transcription cofactor activity
1.62 9.02e-04 GO:0000988 protein binding transcription factor activity
1.62 9.02e-04 GO:0000989 transcription factor binding transcription factor activity
1.20 2.24e-02 GO:0000166 nucleotide binding
1.19 3.18e-15 GO:0005515 protein binding
1.15 4.08e-02 GO:0003676 nucleic acid binding
1.08 1.84e-08 GO:0005488 binding