Motif ID: PAX4.p2

Z-value: 1.235


Transcription factors associated with PAX4.p2:

Gene SymbolEntrez IDGene Name
PAX4 5078 paired box 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX4chr7_-_1270428100.126.7e-01Click!


Activity profile for motif PAX4.p2.

activity profile for motif PAX4.p2


Sorted Z-values histogram for motif PAX4.p2

Sorted Z-values for motif PAX4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_101475149 1.727 S1PR1
sphingosine-1-phosphate receptor 1
chr2_+_223625105 1.439 NM_080671
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr8_-_21827057 1.273 NM_003974
DOK2
docking protein 2, 56kDa
chr20_-_30703219 1.258 NM_182584
C20orf203
chromosome 20 open reading frame 203
chr1_+_101474892 1.170 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr2_-_64944214 1.053


chr6_-_2580296 1.017 NM_152554
C6orf195
chromosome 6 open reading frame 195
chr19_+_2928480 0.950 NM_001143986
NM_024760
TLE6

transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)

chr11_+_1830763 0.925 NM_002339
LSP1
lymphocyte-specific protein 1
chr1_+_20353284 0.826


chr17_+_36515166 0.825 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr20_-_23010786 0.817 CD93
CD93 molecule
chr6_-_105734535 0.812 NM_022361
POPDC3
popeye domain containing 3
chr11_+_72653197 0.797 NM_176796
NM_176797
P2RY6

pyrimidinergic receptor P2Y, G-protein coupled, 6

chr19_+_59833719 0.792 NM_001081638
NM_001081639
NM_001081637
LILRB1


leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1


chr6_+_34964999 0.780 NM_015245
ANKS1A
ankyrin repeat and sterile alpha motif domain containing 1A
chr22_-_30018329 0.780 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr20_-_118263 0.724 NM_001037732
DEFB128
defensin, beta 128
chr11_+_57285809 0.710 NM_001085458
NM_001085459
NM_001085460
NM_001085461
NM_001085462
NM_001085463
NM_001085464
NM_001085465
NM_001085466
NM_001085467
NM_001085468
NM_001085469
NM_001331
CTNND1












catenin (cadherin-associated protein), delta 1












chr18_+_71051713 0.703 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr2_-_96351345 0.698


chr2_+_203587807 0.673 NM_001114132
NBEAL1
neurobeachin-like 1
chr8_+_32525269 0.669 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr2_-_10747553 0.658 NM_024894
NOL10
nucleolar protein 10
chr13_+_75232797 0.649 NM_015842
LMO7
LIM domain 7
chr1_-_208024491 0.647 NM_152485
C1orf74
chromosome 1 open reading frame 74
chr17_+_73054614 0.647


chr5_+_150137700 0.639 NM_032947
C5orf62
chromosome 5 open reading frame 62
chr6_-_130072971 0.634 NM_033515
ARHGAP18
Rho GTPase activating protein 18
chr2_+_217206450 0.624 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr1_+_151147646 0.611 NM_005547
IVL
involucrin
chr6_+_15354278 0.610 NM_004973
JARID2
jumonji, AT rich interactive domain 2
chr2_-_217267742 0.602 IGFBP5
insulin-like growth factor binding protein 5
chr1_-_148936123 0.596 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr3_+_120781212 0.595 NM_001125
ADPRH
ADP-ribosylarginine hydrolase
chr12_-_93568336 0.582 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr18_-_59137488 0.579 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr6_+_135558744 0.577 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr12_-_16650697 0.553 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_+_31703387 0.552 NM_173802
METTL20
methyltransferase like 20
chr14_+_38804226 0.550 NM_203354
CTAGE5
CTAGE family, member 5
chr2_-_10747438 0.547 NOL10
nucleolar protein 10
chr1_-_238842071 0.544 NM_022469
GREM2
gremlin 2
chr9_-_5175601 0.542 NM_007179
INSL6
insulin-like 6
chr11_+_28088406 0.538 METTL15
methyltransferase like 15
chr6_+_111409933 0.530 NM_032194
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr10_+_124204168 0.525 NM_001099667
ARMS2
age-related maculopathy susceptibility 2
chr17_-_44037332 0.521 NM_018952
HOXB6
homeobox B6
chr16_+_51646292 0.514 NM_025134
CHD9
chromodomain helicase DNA binding protein 9
chr2_-_232087293 0.513 C2orf52
chromosome 2 open reading frame 52
chr14_-_23623657 0.502 NM_006177
NRL
neural retina leucine zipper
chr17_-_44154878 0.495 NM_032391
PRAC
prostate cancer susceptibility candidate
chr7_+_133884388 0.493 NM_001080538
AKR1B15
aldo-keto reductase family 1, member B15
chr20_+_51023159 0.493 TSHZ2
teashirt zinc finger homeobox 2
chr12_-_53314891 0.483 NM_033277
LACRT
lacritin
chr2_-_121759237 0.483 NM_014553
TFCP2L1
transcription factor CP2-like 1
chr19_-_59516155 0.479 NM_181879
NM_181985
NM_181986
NM_021250
LILRA5



leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5



chr13_-_46368968 0.478 NM_000621
NM_001165947
HTR2A

5-hydroxytryptamine (serotonin) receptor 2A

chr20_-_33580861 0.474 NM_001145350
C20orf173
chromosome 20 open reading frame 173
chr2_-_237987509 0.469 COL6A3
collagen, type VI, alpha 3
chr2_+_217206327 0.466 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr2_-_215711313 0.465 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chrX_+_154880439 0.463 NM_002186
IL9R
interleukin 9 receptor
chr2_-_176656935 0.457 NM_001080458
EVX2
even-skipped homeobox 2
chr4_+_47181987 0.452 NM_020453
ATP10D
ATPase, class V, type 10D
chr3_-_143649472 0.451 NM_001042604
NM_019001
XRN1

5'-3' exoribonuclease 1

chr12_-_16652202 0.450 NM_001001395
LMO3
LIM domain only 3 (rhombotin-like 2)
chr16_+_15435825 0.445 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr5_-_133332173 0.439 NM_020199
C5orf15
chromosome 5 open reading frame 15
chr2_-_237987545 0.439 COL6A3
collagen, type VI, alpha 3
chr2_-_237987553 0.439 COL6A3
collagen, type VI, alpha 3
chr1_-_109420091 0.431 NM_005645
TAF13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr12_-_94469357 0.425 NM_032147
USP44
ubiquitin specific peptidase 44
chr1_-_26571812 0.422 NM_001114759
NM_173574
ZNF683

zinc finger protein 683

chr5_+_108111421 0.422 NM_005246
FER
fer (fps/fes related) tyrosine kinase
chr2_-_237987554 0.422 COL6A3
collagen, type VI, alpha 3
chr6_+_31662454 0.420 NM_205837
LST1
leukocyte specific transcript 1
chr2_+_185171337 0.415 NM_194250
ZNF804A
zinc finger protein 804A
chr11_-_94603857 0.409 NM_144665
SESN3
sestrin 3
chr7_-_38279757 0.405 NM_001003799
NM_001003806
TARP

TRGV9
TCR gamma alternate reading frame protein

T cell receptor gamma variable 9
chr20_-_44426407 0.405 NM_015945
NM_173073
NM_173179
SLC35C2


solute carrier family 35, member C2


chr13_-_28190961 0.402 NM_001135919
NM_181785
SLC46A3

solute carrier family 46, member 3

chr20_-_47307554 0.390 ZNFX1
zinc finger, NFX1-type containing 1
chr6_-_133161318 0.389 NM_052831
C6orf192
chromosome 6 open reading frame 192
chr2_-_237987579 0.388 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr6_+_32713160 0.386 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr4_-_113426332 0.383 NM_052864
TIFA
TRAF-interacting protein with forkhead-associated domain
chr7_+_134567270 0.377 NM_182489
STRA8
stimulated by retinoic acid gene 8 homolog (mouse)
chr7_+_93388951 0.374 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr2_+_190234369 0.370 NM_019048
ASNSD1
asparagine synthetase domain containing 1
chr19_-_59476734 0.369 NM_001080978
NM_005874
LILRB2

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2

chr17_+_69781980 0.369 NM_001172810
NM_023036
DNAI2

dynein, axonemal, intermediate chain 2

chr5_+_162862808 0.367 NM_182796
MAT2B
methionine adenosyltransferase II, beta
chr12_+_120055013 0.365 NM_002562
P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
chr2_+_170259195 0.364 NM_144711
NM_001008489
PHOSPHO2-KLHL23
KLHL23
PHOSPHO2
PHOSPHO2-KLHL23 read-through transcript
kelch-like 23 (Drosophila)
phosphatase, orphan 2
chr2_-_20886293 0.364 NM_021925
C2orf43
chromosome 2 open reading frame 43
chr15_+_79213660 0.363 NM_173528
C15orf26
chromosome 15 open reading frame 26
chr10_-_35419486 0.361 NM_001198777
CUL2
cullin 2
chr3_+_187866464 0.361 NM_000412
HRG
histidine-rich glycoprotein
chr1_+_12046020 0.359 NM_001243
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr4_+_26194643 0.358 NM_018317
TBC1D19
TBC1 domain family, member 19
chr6_+_35308605 0.357 SCUBE3
signal peptide, CUB domain, EGF-like 3
chr4_+_120029426 0.353 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr17_+_55269974 0.348


chr19_+_59796858 0.345 NM_006863
LILRA1
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
chr5_-_93472993 0.345 NM_001163417
NM_001163418
NM_032042
FAM172A


family with sequence similarity 172, member A


chr12_+_103375116 0.341 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr16_-_28528780 0.334 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr4_-_121207338 0.331 NM_002358
MAD2L1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr6_+_31661934 0.329 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr1_-_202730135 0.329 PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr5_+_167846023 0.327 NM_002887
RARS
arginyl-tRNA synthetase
chr6_+_17390910 0.323 NM_153020
RBM24
RNA binding motif protein 24
chr11_+_31347947 0.323 NM_181706
DNAJC24
DnaJ (Hsp40) homolog, subfamily C, member 24
chr17_+_50699965 0.322 HLF
hepatic leukemia factor
chr5_-_137099361 0.319 KLHL3
kelch-like 3 (Drosophila)
chr12_-_28016182 0.319 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr19_-_57243884 0.319 NM_014650
ZNF432
zinc finger protein 432
chr17_+_72376022 0.318 NM_144677
MGAT5B
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr12_+_103677388 0.317 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr22_+_35290271 0.316


chr17_+_4795128 0.314 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr7_-_55897938 0.312 NM_207366
SEPT14
septin 14
chr6_-_117096594 0.309 NM_145062
ZUFSP
zinc finger with UFM1-specific peptidase domain
chr5_+_36644187 0.309 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr22_-_41447214 0.306 A4GALT
alpha 1,4-galactosyltransferase
chr15_+_49988882 0.304 TMOD3
tropomodulin 3 (ubiquitous)
chr2_-_213723298 0.304 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr8_-_102029997 0.304 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr2_-_40593074 0.304 NM_001112802
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr2_-_218551786 0.300 TNS1
tensin 1
chr5_-_169340321 0.300 NM_001129891
FAM196B
family with sequence similarity 196, member B
chr17_-_30414789 0.298 NM_001017368
RFFL
ring finger and FYVE-like domain containing 1
chr11_+_6475065 0.297 NM_144666
NM_173589
DNHD1

dynein heavy chain domain 1

chr1_+_234624266 0.297 NM_145861
EDARADD
EDAR-associated death domain
chr3_+_51870684 0.297 NM_203424
IQCF2
IQ motif containing F2
chr3_-_79899748 0.296 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr2_-_198248828 0.294 NM_144629
RFTN2
raftlin family member 2
chr7_+_26298136 0.291 SNX10
sorting nexin 10
chr2_+_73973600 0.291 NM_001615
ACTG2
actin, gamma 2, smooth muscle, enteric
chr15_-_32289480 0.289 C15orf29
chromosome 15 open reading frame 29
chr2_-_170259105 0.285 NM_001085447
C2orf77
chromosome 2 open reading frame 77
chr9_-_4289915 0.283 GLIS3
GLIS family zinc finger 3
chr16_+_70437394 0.282 NM_001137675
ATXN1L
ataxin 1-like
chr6_+_134800533 0.280 LOC154092
hypothetical LOC154092
chr18_-_51406359 0.278 TCF4
transcription factor 4
chr4_+_39874921 0.278 NM_004310
RHOH
ras homolog gene family, member H
chr12_+_56284867 0.277 NM_178502
DTX3
deltex homolog 3 (Drosophila)
chr10_-_69661860 0.274 NM_145178
ATOH7
atonal homolog 7 (Drosophila)
chr12_-_121224676 0.272 NM_001014336
IL31
interleukin 31
chr22_-_41095123 0.270


chr10_-_116276560 0.268 ABLIM1
actin binding LIM protein 1
chr4_-_174557191 0.263 NM_007281
SCRG1
stimulator of chondrogenesis 1
chr9_+_78305368 0.263 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr2_+_122124034 0.263 LOC254128
hypothetical LOC254128
chr7_+_116238309 0.252 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr15_-_80428760 0.251 NM_001164465
GOLGA6L10
golgin A6 family-like 10
chr2_+_12774264 0.251 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr2_+_99163968 0.251 NM_145212
MRPL30
mitochondrial ribosomal protein L30
chr18_-_22696532 0.247 NM_004028
AQP4
aquaporin 4
chr3_-_143649552 0.247 XRN1
5'-3' exoribonuclease 1
chr17_+_40655060 0.246 NM_005892
FMNL1
formin-like 1
chr6_+_158990982 0.243 NM_001009991
SYTL3
synaptotagmin-like 3
chr1_+_34098662 0.243 NM_145205
HMGB4
high-mobility group box 4
chr8_+_67507271 0.242 NM_144650
ADHFE1
alcohol dehydrogenase, iron containing, 1
chr2_+_99164064 0.241 MRPL30
mitochondrial ribosomal protein L30
chr2_-_222145240 0.241 NM_004438
EPHA4
EPH receptor A4
chr4_+_113958652 0.240 NM_001127493
ANK2
ankyrin 2, neuronal
chr6_+_26381122 0.239 NM_003525
HIST1H2BI
histone cluster 1, H2bi
chr11_+_124967961 0.239 STT3A
STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
chr17_-_24973940 0.238 CORO6
coronin 6
chr4_-_187114863 0.237 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr2_+_173308880 0.237 RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr12_-_102967828 0.237 GLT8D2
glycosyltransferase 8 domain containing 2
chr6_+_31690957 0.236 NM_004847
NM_001623
AIF1

allograft inflammatory factor 1

chr9_-_135923373 0.233 BRD3
bromodomain containing 3
chr19_+_14405100 0.233 NM_002741
PKN1
protein kinase N1
chr5_+_42792676 0.230 NM_001134848
CCDC152
coiled-coil domain containing 152
chr8_+_86563382 0.230 NM_000067
CA2
carbonic anhydrase II
chr19_+_46121963 0.229 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr4_-_109308893 0.227 NM_001130713
NM_001130714
NM_016269
LEF1


lymphoid enhancer-binding factor 1


chr20_-_51644187 0.226 ZNF217
zinc finger protein 217
chr3_-_73756668 0.225 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr20_-_33783409 0.225 RBM39
RNA binding motif protein 39
chr14_-_19951417 0.223 NM_007110
TEP1
telomerase-associated protein 1
chr4_-_88531353 0.222 NM_016245
HSD17B11
hydroxysteroid (17-beta) dehydrogenase 11
chr3_-_157755603 0.220 NM_007107
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr19_-_60528480 0.219 NM_001085488
TMEM150B
transmembrane protein 150B
chr5_+_115448592 0.219 NM_016144
COMMD10
COMM domain containing 10
chr1_-_238842011 0.217 GREM2
gremlin 2
chr11_-_59334706 0.214 NM_017840
MRPL16
mitochondrial ribosomal protein L16
chr2_-_37269193 0.213 NM_001032377
SULT6B1
sulfotransferase family, cytosolic, 6B, member 1
chr18_+_12981329 0.213 NM_032142
CEP192
centrosomal protein 192kDa
chr4_-_82345224 0.211 NM_006259
PRKG2
protein kinase, cGMP-dependent, type II
chr4_-_40212670 0.211 NM_019027
RBM47
RNA binding motif protein 47
chr20_-_19984685 0.210 NM_016652
CRNKL1
crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr9_-_88064338 0.209 NM_001010907
C9orf153
chromosome 9 open reading frame 153
chr12_+_69148120 0.209


chr6_+_26071255 0.209 TRIM38
tripartite motif containing 38
chr7_+_26158257 0.207 NM_004289
NFE2L3
nuclear factor (erythroid-derived 2)-like 3

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.