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• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: PAX5.p2

Z-value: 2.958

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr8_+_22513043	3.555	NM_001013842 NM_001198827 NM_173686	C8orf58	chromosome 8 open reading frame 58
chr8_-_99906944	3.309	NM_006281	STK3	serine/threonine kinase 3
chr5_+_76047536	2.914	NM_001992	F2R	coagulation factor II (thrombin) receptor
chr2_+_235525355	2.611	NM_014521	SH3BP4	SH3-domain binding protein 4
chr1_-_22136263	2.429	NM_005529	HSPG2	heparan sulfate proteoglycan 2
chr4_+_3264509	2.400		RGS12	regulator of G-protein signaling 12
chr11_-_2907169	2.391	NM_003311	PHLDA2	pleckstrin homology-like domain, family A, member 2
chr20_-_43410437	2.342	NM_002999	SDC4	syndecan 4
chr1_+_25999245	2.226	NM_020451 NM_206926	SEPN1	selenoprotein N, 1
chr4_-_809879	2.215	NM_006651	CPLX1	complexin 1
chr7_-_525556	2.189		PDGFA	platelet-derived growth factor alpha polypeptide
chr7_+_5289079	2.104	NM_001040661 NM_153247	SLC29A4	solute carrier family 29 (nucleoside transporters), member 4
chr14_+_99329198	2.087	NM_001008707 NM_004434	EML1	echinoderm microtubule associated protein like 1
chr2_+_10101081	1.996	NM_003597 NM_001177716	KLF11	Kruppel-like factor 11
chr3_-_71857097	1.948	NM_001134651	EIF4E3	eukaryotic translation initiation factor 4E family member 3
chr17_+_77582774	1.935	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr18_-_802268	1.907	NM_005433	YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr8_+_1699418	1.851		CLN8	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr3_-_125085834	1.823	NM_053025 NM_053026 NM_053027 NM_053028	MYLK	myosin light chain kinase
chr19_-_1518875	1.814	NM_001174118 NM_203304	MEX3D	mex-3 homolog D (C. elegans)
chr17_-_39265965	1.798	NM_001932	MPP3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr6_+_12120709	1.788	NM_002114	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1
chr16_+_88422354	1.767	NM_032451	SPIRE2	spire homolog 2 (Drosophila)
chr22_-_41913076	1.763	NM_015140	TTLL12	tubulin tyrosine ligase-like family, member 12
chr21_+_46226072	1.759	NM_001848	COL6A1	collagen, type VI, alpha 1
chr22_+_48966480	1.756	NM_025204	TRABD	TraB domain containing
chr13_-_105985313	1.752	NM_004093	EFNB2	ephrin-B2
chr22_+_48966394	1.720		TRABD	TraB domain containing
chr22_-_41913002	1.694		TTLL12	tubulin tyrosine ligase-like family, member 12
chrX_+_43399101	1.688		MAOA	monoamine oxidase A
chr11_+_359723	1.684	NM_178537	B4GALNT4	beta-1,4-N-acetyl-galactosaminyl transferase 4
chr11_+_101485946	1.679	NM_001130145 NM_001195044 NM_006106	YAP1	Yes-associated protein 1
chr10_-_30064600	1.657	NM_003174	SVIL	supervillin
chr20_-_38751289	1.650	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr22_-_41913075	1.628		TTLL12	tubulin tyrosine ligase-like family, member 12
chr8_+_136538739	1.618	NM_006558	KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3
chr11_+_12652427	1.618	NM_021961	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr6_-_138470160	1.615	NM_022121	PERP	PERP, TP53 apoptosis effector
chr17_-_78199384	1.610	NM_019613	WDR45L	WDR45-like
chr1_-_223907283	1.587	NM_001008493 NM_018212	ENAH	enabled homolog (Drosophila)
chr1_+_113734997	1.565	NM_001142782 NM_152900	MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3
chr2_-_36384	1.554	NM_001077710	FAM110C	family with sequence similarity 110, member C
chr8_+_1699276	1.546	NM_018941	CLN8	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr11_+_35922106	1.532	NM_174902	LDLRAD3	low density lipoprotein receptor class A domain containing 3
chr3_-_51976428	1.523	NM_020418 NM_001174100 NM_033008	PCBP4	poly(rC) binding protein 4
chr7_-_101906311	1.503	NM_006234	POLR2J2 POLR2J	polymerase (RNA) II (DNA directed) polypeptide J2 polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
chr14_+_67069668	1.498	NM_020715	PLEKHH1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr10_-_105604942	1.493	NM_014631	SH3PXD2A	SH3 and PX domains 2A
chr13_+_43845977	1.487	NM_001010897	SERP2	stress-associated endoplasmic reticulum protein family member 2
chr7_-_28186671	1.486		JAZF1	JAZF zinc finger 1
chr20_-_3336586	1.479		C20orf194	chromosome 20 open reading frame 194
chr7_+_44110470	1.478	NM_001129	AEBP1	AE binding protein 1
chr8_-_142080169	1.460	NM_005607 NM_153831	PTK2	PTK2 protein tyrosine kinase 2
chr2_-_16710551	1.444	NM_030797	FAM49A	family with sequence similarity 49, member A
chr2_-_127694123	1.412		CYP27C1	cytochrome P450, family 27, subfamily C, polypeptide 1
chr2_-_235070431	1.407	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr14_+_20608179	1.407	NM_018071	ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40
chr14_+_93710401	1.407	NM_020958 NM_058237	PPP4R4	protein phosphatase 4, regulatory subunit 4
chr2_-_204108151	1.396	NM_203365 NM_213589	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr15_-_88159061	1.395	NM_001150	ANPEP	alanyl (membrane) aminopeptidase
chr1_+_32979930	1.395	NM_020888	KIAA1522	KIAA1522
chr16_+_1604641	1.366	NM_020825	CRAMP1L	Crm, cramped-like (Drosophila)
chr4_+_152549776	1.364	NM_001109977	FAM160A1	family with sequence similarity 160, member A1
chr8_-_13034873	1.360		DLC1	deleted in liver cancer 1
chr14_-_99842519	1.359	NM_001039355	SLC25A29	solute carrier family 25, member 29
chr18_+_7557313	1.352	NM_001105244 NM_002845	PTPRM	protein tyrosine phosphatase, receptor type, M
chr8_+_25097983	1.349		DOCK5	dedicator of cytokinesis 5
chr3_-_127558747	1.342	NM_014079	KLF15	Kruppel-like factor 15
chr20_+_55359551	1.320	NM_003610	RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr6_+_158164269	1.319	NM_016224	SNX9	sorting nexin 9
chr2_-_171725150	1.314		TLK1	tousled-like kinase 1
chr2_+_159533329	1.309	NM_001145909 NM_033394	TANC1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr1_+_43769065	1.307	NM_002840 NM_130440	PTPRF	protein tyrosine phosphatase, receptor type, F
chr17_-_39265705	1.304		MPP3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chrX_+_18353623	1.303	NM_003159	CDKL5	cyclin-dependent kinase-like 5
chr20_-_60375695	1.298	NM_005560	LAMA5	laminin, alpha 5
chr20_+_55359706	1.291		RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr4_-_7991992	1.288	NM_001134647 NM_198595	AFAP1	actin filament associated protein 1
chr21_+_45318861	1.282	NM_001112 NM_001160230 NM_015833 NM_015834	ADARB1	adenosine deaminase, RNA-specific, B1
chr11_+_117983515	1.273	NM_001144758 NM_001144759	PHLDB1	pleckstrin homology-like domain, family B, member 1
chr5_-_114533448	1.271		TRIM36	tripartite motif containing 36
chr16_-_65287967	1.258	NM_178818 NM_181521	CMTM4	CKLF-like MARVEL transmembrane domain containing 4
chr11_-_27679022	1.255	NM_001143812	BDNF	brain-derived neurotrophic factor
chr14_-_52487558	1.248	NM_001134999 NM_001135000 NM_006832	FERMT2	fermitin family member 2
chr13_+_26029879	1.240		WASF3	WAS protein family, member 3
chr21_+_45649429	1.235	NM_130445	COL18A1	collagen, type XVIII, alpha 1
chr5_+_52320660	1.234	NM_002203	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr1_-_115433570	1.232	NM_005725	TSPAN2	tetraspanin 2
chr7_+_128257698	1.232	NM_001127487 NM_001458	FLNC	filamin C, gamma
chr1_-_93919789	1.227	NM_003567	BCAR3	breast cancer anti-estrogen resistance 3
chr7_+_115926855	1.224		CAV2	caveolin 2
chr5_+_172000793	1.220	NM_001142651	NEURL1B	neuralized homolog 1B (Drosophila)
chr1_+_204049053	1.191
chr21_+_32706615	1.191	NM_058187	C21orf63	chromosome 21 open reading frame 63
chr7_-_526005	1.182	NM_002607 NM_033023	PDGFA	platelet-derived growth factor alpha polypeptide
chr17_-_71386229	1.173	NM_033452	TRIM47	tripartite motif containing 47
chr2_+_10101822	1.169	NM_001177718	KLF11	Kruppel-like factor 11
chr2_+_10009242	1.163	NM_198182	GRHL1	grainyhead-like 1 (Drosophila)
chr3_+_160964574	1.163		SCHIP1	schwannomin interacting protein 1
chr15_-_27901828	1.159	NM_003257 NM_175610	TJP1	tight junction protein 1 (zona occludens 1)
chr9_+_137511448	1.154	NM_014811	KIAA0649	KIAA0649
chr19_-_55914837	1.153
chr3_-_187025501	1.149	NM_001007225 NM_006548	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr2_-_101134146	1.145	NM_001102426	TBC1D8	TBC1 domain family, member 8 (with GRAM domain)
chr19_+_50004134	1.139	NM_001013257 NM_005581	BCAM	basal cell adhesion molecule (Lutheran blood group)
chr8_+_22479115	1.131	NM_001018003	SORBS3	sorbin and SH3 domain containing 3
chr22_+_37193961	1.130	NM_006855 NM_016657	KDELR3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr14_-_94855848	1.129	NM_024734	CLMN	calmin (calponin-like, transmembrane)
chr14_-_64638809	1.119		MAX	MYC associated factor X
chr12_+_13044604	1.119		HTR7P1	5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
chr1_+_117253882	1.114	NM_020440	PTGFRN	prostaglandin F2 receptor negative regulator
chr19_+_39664706	1.101	NM_001080436	WTIP	Wilms tumor 1 interacting protein
chr11_-_94603857	1.100	NM_144665	SESN3	sestrin 3
chr14_-_104515738	1.096	NM_138420	AHNAK2	AHNAK nucleoprotein 2
chrX_+_17665483	1.091	NM_001037535 NM_001037536 NM_001037540 NM_006746	SCML1	sex comb on midleg-like 1 (Drosophila)
chr14_-_52487386	1.082		FERMT2	fermitin family member 2
chr21_-_39607288	1.081		BRWD1	bromodomain and WD repeat domain containing 1
chr9_+_129414287	1.075	NM_001032221 NM_003165	STXBP1	syntaxin binding protein 1
chr19_-_11390948	1.072	NM_001035223 NM_001161616	RGL3	ral guanine nucleotide dissociation stimulator-like 3
chr7_-_117300763	1.070	NM_033427	CTTNBP2	cortactin binding protein 2
chr6_+_158164294	1.062		SNX9	sorting nexin 9
chr15_+_92575767	1.061		MCTP2	multiple C2 domains, transmembrane 2
chr4_-_86106567	1.057	NM_014991	WDFY3	WD repeat and FYVE domain containing 3
chr8_-_10625352	1.055	NM_031439	SOX7	SRY (sex determining region Y)-box 7
chrX_-_152853402	1.052	NM_003491	NAA10	N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr12_-_13044314	1.052		HEBP1	heme binding protein 1
chr11_-_47164514	1.048	NM_001184974 NM_016223	PACSIN3	protein kinase C and casein kinase substrate in neurons 3
chr2_+_8739563	1.045	NM_002166	ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr19_+_40900965	1.043		MLL4	myeloid/lymphoid or mixed-lineage leukemia 4
chr2_+_54536780	1.034	NM_003128	SPTBN1	spectrin, beta, non-erythrocytic 1
chr5_-_171814026	1.034	NM_001017995	SH3PXD2B	SH3 and PX domains 2B
chr17_-_43470134	1.033	NM_016429	COPZ2	coatomer protein complex, subunit zeta 2
chr1_+_945331	1.032	NM_198576	AGRN	agrin
chr14_+_74815233	1.031	NM_005252	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr12_+_2938703	1.029	NM_003213 NM_201441 NM_201443	TEAD4	TEA domain family member 4
chr22_+_48951286	1.028	NM_001160300 NM_052839	PANX2	pannexin 2
chr4_+_77446700	1.028	NM_003943	STBD1	starch binding domain 1
chrX_+_51092407	1.025		NUDT10	nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr1_-_85131439	1.020	NM_012152	LPAR3	lysophosphatidic acid receptor 3
chr11_-_27678551	1.019	NM_001143813 NM_001143814 NM_001709	BDNF	brain-derived neurotrophic factor
chr3_-_185461768	1.014	NM_033259	CAMK2N2	calcium/calmodulin-dependent protein kinase II inhibitor 2
chr12_+_970613	1.013	NM_178039 NM_178040	ERC1	ELKS/RAB6-interacting/CAST family member 1
chr3_+_161955980	1.012		PPM1L	protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr1_+_15957832	1.008	NM_017556	FBLIM1	filamin binding LIM protein 1
chr11_-_27450808	1.004	NM_018490	LGR4	leucine-rich repeat containing G protein-coupled receptor 4
chr8_-_18915443	0.996	NM_015310	PSD3	pleckstrin and Sec7 domain containing 3
chr6_-_80713589	0.981	NM_022726	ELOVL4	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr19_+_15079141	0.980	NM_033025	SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr7_-_139123906	0.974	NM_001113239 NM_022740	HIPK2	homeodomain interacting protein kinase 2
chr1_+_945472	0.974		AGRN	agrin
chr1_+_24701886	0.974	NM_013441	RCAN3	RCAN family member 3
chr2_+_33025872	0.968	NM_206943	LTBP1	latent transforming growth factor beta binding protein 1
chr19_+_38979502	0.960	NM_001129994 NM_001129995 NM_024076	KCTD15	potassium channel tetramerisation domain containing 15
chr6_+_83130673	0.958	NM_001166392	TPBG	trophoblast glycoprotein
chr12_-_13044448	0.957		HEBP1	heme binding protein 1
chr19_-_51168396	0.957	NM_002516	NOVA2	neuro-oncological ventral antigen 2
chr1_-_117011824	0.956	NM_001007237 NM_001542	IGSF3	immunoglobulin superfamily, member 3
chr21_+_41461962	0.949		BACE2	beta-site APP-cleaving enzyme 2
chr1_-_1465602	0.949	NM_001114748	C1orf70	chromosome 1 open reading frame 70
chr8_-_13035102	0.948	NM_006094	DLC1	deleted in liver cancer 1
chr13_+_26029799	0.947	NM_006646	WASF3	WAS protein family, member 3
chr13_-_76499297	0.944	NM_012158	FBXL3	F-box and leucine-rich repeat protein 3
chr9_-_76692082	0.940	NM_001177311	TRPM6	transient receptor potential cation channel, subfamily M, member 6
chr6_-_105734535	0.938	NM_022361	POPDC3	popeye domain containing 3
chr19_-_15421761	0.936	NM_021241	WIZ	widely interspaced zinc finger motifs
chr9_+_494661	0.935	NM_015158	KANK1	KN motif and ankyrin repeat domains 1
chr5_-_171813960	0.921		SH3PXD2B	SH3 and PX domains 2B
chr9_+_139892049	0.920	NM_000718	CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit
chr12_-_13044467	0.920	NM_015987	HEBP1	heme binding protein 1
chr4_-_177950658	0.918	NM_005429	VEGFC	vascular endothelial growth factor C
chr12_-_103055924	0.917	NM_006166	NFYB	nuclear transcription factor Y, beta
chr12_+_3056781	0.916	NM_001168320 NM_006675	TSPAN9	tetraspanin 9
chr20_+_336941	0.915		RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr9_-_73573121	0.913	NM_001135820 NM_013390	TMEM2	transmembrane protein 2
chr1_+_64983312	0.907	NM_018211	RAVER2	ribonucleoprotein, PTB-binding 2
chr16_-_265868	0.904	NM_003834 NM_183337	RGS11	regulator of G-protein signaling 11
chr12_+_120322226	0.899	NM_025126 NM_194271	RNF34	ring finger protein 34
chr1_-_33139425	0.892	NM_033504	TMEM54	transmembrane protein 54
chr17_-_45562112	0.892	NM_174920	SAMD14	sterile alpha motif domain containing 14
chr12_-_41269679	0.890	NM_153026	PRICKLE1	prickle homolog 1 (Drosophila)
chr20_-_60074237	0.887	NM_003185	TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr11_-_86343859	0.885	NM_012193	FZD4	frizzled homolog 4 (Drosophila)
chr17_-_6400470	0.880	NM_001165966 NM_031220	PITPNM3	PITPNM family member 3
chr4_-_125853166	0.880	NM_001167882 NM_020337	ANKRD50	ankyrin repeat domain 50
chr12_+_2939250	0.879		TEAD4	TEA domain family member 4
chr12_+_26003218	0.875	NM_001164748 NM_007211	RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr2_-_9061193	0.870	NM_138799	MBOAT2	membrane bound O-acyltransferase domain containing 2
chr15_+_67239853	0.867	NM_015554	GLCE	glucuronic acid epimerase
chr7_+_89678935	0.865	NM_152999 NM_001040665	STEAP2	six transmembrane epithelial antigen of the prostate 2
chr14_+_104402626	0.863	NM_001112726 NM_015005	KIAA0284	KIAA0284
chr1_-_3437834	0.863		MEGF6	multiple EGF-like-domains 6
chr1_-_109386112	0.862	NM_001142550 NM_001142551 NM_014969	WDR47	WD repeat domain 47
chr10_-_15250616	0.862	NM_004808	NMT2	N-myristoyltransferase 2
chr19_+_61742111	0.860	NM_020828	ZFP28	zinc finger protein 28 homolog (mouse)
chr4_+_154606900	0.860	NM_001131007 NM_015196	KIAA0922	KIAA0922
chr10_-_62373828	0.859	NM_014836	RHOBTB1	Rho-related BTB domain containing 1
chr2_-_8895129	0.858	NM_020738	KIDINS220	kinase D-interacting substrate, 220kDa
chr1_-_166372526	0.856		GPR161	G protein-coupled receptor 161
chr7_-_28186867	0.853	NM_175061	JAZF1	JAZF zinc finger 1
chr5_-_131591380	0.852	NM_001017974 NM_001142598 NM_001142599	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.09	8.47e-21	GO:0009987	cellular process
1.13	5.51e-16	GO:0050794	regulation of cellular process
1.12	1.54e-14	GO:0050789	regulation of biological process
1.11	3.97e-14	GO:0065007	biological regulation
1.26	8.48e-14	GO:0048523	negative regulation of cellular process
1.13	8.61e-13	GO:0044237	cellular metabolic process
1.32	1.31e-12	GO:0009966	regulation of signal transduction
1.16	5.60e-12	GO:0044260	cellular macromolecule metabolic process
1.25	3.03e-10	GO:0043412	macromolecule modification
1.22	3.54e-10	GO:0048519	negative regulation of biological process
1.25	4.60e-10	GO:0006464	protein modification process
1.15	9.15e-10	GO:0051716	cellular response to stimulus
1.26	1.02e-09	GO:0023051	regulation of signaling
1.21	1.17e-09	GO:0044267	cellular protein metabolic process
1.10	3.39e-09	GO:0008152	metabolic process
1.17	4.84e-09	GO:0007165	signal transduction
1.11	4.94e-09	GO:0044238	primary metabolic process
1.20	4.69e-08	GO:0048522	positive regulation of cellular process
1.13	4.93e-08	GO:0043170	macromolecule metabolic process
1.15	8.19e-08	GO:0023052	signaling
1.18	1.01e-07	GO:0048518	positive regulation of biological process
1.46	2.08e-06	GO:0009968	negative regulation of signal transduction
1.21	2.50e-06	GO:0048583	regulation of response to stimulus
1.23	2.68e-06	GO:0009653	anatomical structure morphogenesis
1.24	4.89e-06	GO:0035556	intracellular signal transduction
1.13	9.12e-06	GO:0019222	regulation of metabolic process
1.13	1.61e-05	GO:0031323	regulation of cellular metabolic process
1.15	1.64e-05	GO:0019538	protein metabolic process
1.14	1.85e-05	GO:0016043	cellular component organization
1.13	4.84e-05	GO:0080090	regulation of primary metabolic process
1.41	5.05e-05	GO:0010648	negative regulation of cell communication
1.32	5.41e-05	GO:0019220	regulation of phosphate metabolic process
1.32	5.41e-05	GO:0051174	regulation of phosphorus metabolic process
1.13	8.03e-05	GO:0060255	regulation of macromolecule metabolic process
1.13	8.18e-05	GO:0071840	cellular component organization or biogenesis
1.29	1.08e-04	GO:0051128	regulation of cellular component organization
1.29	1.21e-04	GO:0031399	regulation of protein modification process
1.39	1.29e-04	GO:0023057	negative regulation of signaling
1.32	1.46e-04	GO:0042325	regulation of phosphorylation
1.27	1.52e-04	GO:0022008	neurogenesis
1.32	2.04e-04	GO:0030030	cell projection organization
1.24	2.53e-04	GO:0008104	protein localization
1.32	2.54e-04	GO:0007167	enzyme linked receptor protein signaling pathway
1.26	2.76e-04	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.32	2.84e-04	GO:0001932	regulation of protein phosphorylation
1.20	2.85e-04	GO:0007399	nervous system development
1.53	3.69e-04	GO:0048011	nerve growth factor receptor signaling pathway
1.45	4.16e-04	GO:0060284	regulation of cell development
1.86	4.39e-04	GO:0060828	regulation of canonical Wnt receptor signaling pathway
1.21	4.74e-04	GO:0033036	macromolecule localization
1.35	5.69e-04	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.26	5.91e-04	GO:0050793	regulation of developmental process
1.26	6.57e-04	GO:0045184	establishment of protein localization
1.30	7.39e-04	GO:0045595	regulation of cell differentiation
1.26	8.87e-04	GO:0015031	protein transport
1.14	9.12e-04	GO:0071842	cellular component organization at cellular level
1.13	9.24e-04	GO:0048856	anatomical structure development
1.32	1.02e-03	GO:0000902	cell morphogenesis
1.24	1.16e-03	GO:0006793	phosphorus metabolic process
1.24	1.16e-03	GO:0006796	phosphate metabolic process
1.12	1.18e-03	GO:0051179	localization
1.26	1.32e-03	GO:0048699	generation of neurons
1.23	1.34e-03	GO:0010941	regulation of cell death
1.67	1.38e-03	GO:0030111	regulation of Wnt receptor signaling pathway
1.16	1.44e-03	GO:0048869	cellular developmental process
1.19	1.51e-03	GO:0065009	regulation of molecular function
1.50	1.51e-03	GO:0051129	negative regulation of cellular component organization
1.30	2.01e-03	GO:0032989	cellular component morphogenesis
1.39	2.03e-03	GO:0051056	regulation of small GTPase mediated signal transduction
1.23	2.25e-03	GO:0043067	regulation of programmed cell death
1.11	2.54e-03	GO:0032502	developmental process
1.33	2.72e-03	GO:0048585	negative regulation of response to stimulus
1.13	2.80e-03	GO:0071841	cellular component organization or biogenesis at cellular level
1.36	2.99e-03	GO:0008285	negative regulation of cell proliferation
1.23	3.25e-03	GO:0042981	regulation of apoptosis
1.33	3.40e-03	GO:0000904	cell morphogenesis involved in differentiation
1.16	3.54e-03	GO:0030154	cell differentiation
1.23	3.82e-03	GO:0032268	regulation of cellular protein metabolic process
1.43	3.83e-03	GO:0001944	vasculature development
1.24	3.92e-03	GO:0048468	cell development
1.23	4.08e-03	GO:0009892	negative regulation of metabolic process
1.22	4.27e-03	GO:0007049	cell cycle
1.22	4.33e-03	GO:0051246	regulation of protein metabolic process
1.24	4.36e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.13	5.29e-03	GO:0051171	regulation of nitrogen compound metabolic process
1.20	5.65e-03	GO:0051641	cellular localization
1.61	5.90e-03	GO:0016055	Wnt receptor signaling pathway
1.32	6.39e-03	GO:0043549	regulation of kinase activity
2.00	6.46e-03	GO:0090090	negative regulation of canonical Wnt receptor signaling pathway
1.33	7.09e-03	GO:0072358	cardiovascular system development
1.33	7.09e-03	GO:0072359	circulatory system development
1.13	7.10e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25	7.19e-03	GO:0033554	cellular response to stress
1.42	9.05e-03	GO:0051270	regulation of cellular component movement
1.12	9.49e-03	GO:0048731	system development
1.20	9.68e-03	GO:0010604	positive regulation of macromolecule metabolic process
1.44	9.93e-03	GO:0030334	regulation of cell migration
1.23	1.00e-02	GO:0031324	negative regulation of cellular metabolic process
1.26	1.01e-02	GO:0006468	protein phosphorylation
1.20	1.07e-02	GO:0031325	positive regulation of cellular metabolic process
1.43	1.13e-02	GO:2000145	regulation of cell motility
1.25	1.14e-02	GO:0046907	intracellular transport
1.41	1.30e-02	GO:0040012	regulation of locomotion
1.25	1.41e-02	GO:2000026	regulation of multicellular organismal development
1.19	1.42e-02	GO:0009893	positive regulation of metabolic process
1.77	1.69e-02	GO:0030178	negative regulation of Wnt receptor signaling pathway
1.25	1.73e-02	GO:0012501	programmed cell death
1.30	1.74e-02	GO:0051338	regulation of transferase activity
1.25	1.92e-02	GO:0006915	apoptosis
1.30	2.30e-02	GO:0032990	cell part morphogenesis
1.30	2.33e-02	GO:0031175	neuron projection development
1.92	2.40e-02	GO:0046519	sphingoid metabolic process
1.31	2.73e-02	GO:0045859	regulation of protein kinase activity
1.21	2.82e-02	GO:0042127	regulation of cell proliferation
1.30	2.84e-02	GO:0048858	cell projection morphogenesis
1.24	3.47e-02	GO:0051173	positive regulation of nitrogen compound metabolic process
1.31	3.55e-02	GO:0048812	neuron projection morphogenesis
1.31	4.09e-02	GO:0060548	negative regulation of cell death
1.31	4.11e-02	GO:0048667	cell morphogenesis involved in neuron differentiation
1.87	4.13e-02	GO:0042058	regulation of epidermal growth factor receptor signaling pathway
1.10	4.19e-02	GO:0007275	multicellular organismal development
1.26	4.47e-02	GO:0045893	positive regulation of transcription, DNA-dependent
1.22	4.63e-02	GO:0008219	cell death
1.12	4.94e-02	GO:0031326	regulation of cellular biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.10	9.02e-36	GO:0005622	intracellular
1.10	4.77e-34	GO:0044424	intracellular part
1.15	5.02e-33	GO:0005737	cytoplasm
1.10	5.94e-21	GO:0043226	organelle
1.10	1.05e-20	GO:0043229	intracellular organelle
1.15	1.09e-19	GO:0044444	cytoplasmic part
1.11	1.59e-19	GO:0043227	membrane-bounded organelle
1.11	2.98e-19	GO:0043231	intracellular membrane-bounded organelle
1.26	2.08e-14	GO:0005829	cytosol
1.12	6.79e-11	GO:0005634	nucleus
1.03	1.38e-10	GO:0005623	cell
1.03	1.77e-10	GO:0044464	cell part
1.11	7.13e-08	GO:0044422	organelle part
1.75	2.55e-07	GO:0005912	adherens junction
1.10	3.58e-07	GO:0044446	intracellular organelle part
1.67	2.20e-06	GO:0070161	anchoring junction
1.16	4.32e-05	GO:0070013	intracellular organelle lumen
1.79	6.24e-05	GO:0005925	focal adhesion
1.15	7.24e-05	GO:0043233	organelle lumen
1.16	9.31e-05	GO:0044428	nuclear part
1.15	1.05e-04	GO:0031974	membrane-enclosed lumen
1.73	2.42e-04	GO:0005924	cell-substrate adherens junction
1.48	3.16e-04	GO:0016323	basolateral plasma membrane
1.69	5.32e-04	GO:0030055	cell-substrate junction
1.16	5.38e-04	GO:0031981	nuclear lumen
1.22	6.16e-04	GO:0005794	Golgi apparatus
1.19	9.83e-04	GO:0005654	nucleoplasm
1.51	1.69e-03	GO:0031252	cell leading edge
1.16	2.46e-03	GO:0012505	endomembrane system
1.12	2.86e-03	GO:0043228	non-membrane-bounded organelle
1.12	2.86e-03	GO:0043232	intracellular non-membrane-bounded organelle
1.16	3.23e-03	GO:0005856	cytoskeleton
2.05	3.98e-03	GO:0008287	protein serine/threonine phosphatase complex
1.26	4.79e-03	GO:0030054	cell junction
1.12	2.02e-02	GO:0031090	organelle membrane
1.50	2.12e-02	GO:0005769	early endosome
1.22	2.73e-02	GO:0015630	microtubule cytoskeleton
1.31	3.05e-02	GO:0048471	perinuclear region of cytoplasm
1.62	4.02e-02	GO:0016327	apicolateral plasma membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.14	1.10e-23	GO:0005515	protein binding
1.07	5.23e-14	GO:0005488	binding
1.44	8.13e-08	GO:0030695	GTPase regulator activity
1.43	1.39e-07	GO:0060589	nucleoside-triphosphatase regulator activity
1.41	4.75e-06	GO:0019904	protein domain specific binding
1.17	1.39e-05	GO:0000166	nucleotide binding
1.27	1.47e-05	GO:0030234	enzyme regulator activity
1.29	5.71e-05	GO:0019899	enzyme binding
1.18	8.28e-05	GO:0035639	purine ribonucleoside triphosphate binding
1.28	9.17e-05	GO:0016301	kinase activity
1.17	9.34e-05	GO:0032553	ribonucleotide binding
1.17	9.34e-05	GO:0032555	purine ribonucleotide binding
1.17	1.10e-04	GO:0017076	purine nucleotide binding
1.19	3.71e-04	GO:0005524	ATP binding
1.24	4.77e-04	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.18	6.38e-04	GO:0030554	adenyl nucleotide binding
1.18	6.59e-04	GO:0032559	adenyl ribonucleotide binding
1.31	7.86e-04	GO:0008092	cytoskeletal protein binding
1.35	7.97e-04	GO:0004674	protein serine/threonine kinase activity
1.26	1.47e-03	GO:0042802	identical protein binding
1.40	2.48e-03	GO:0008134	transcription factor binding
1.25	2.79e-03	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.34	3.02e-03	GO:0008047	enzyme activator activity
1.39	5.59e-03	GO:0005083	small GTPase regulator activity
1.63	5.94e-03	GO:0017124	SH3 domain binding
1.08	6.41e-03	GO:0003824	catalytic activity
2.02	7.67e-03	GO:0019888	protein phosphatase regulator activity
1.26	9.23e-03	GO:0004672	protein kinase activity
1.92	1.36e-02	GO:0019208	phosphatase regulator activity
1.14	2.12e-02	GO:0016740	transferase activity
1.38	2.66e-02	GO:0005096	GTPase activator activity
1.47	3.58e-02	GO:0000287	magnesium ion binding
1.47	4.58e-02	GO:0004721	phosphoprotein phosphatase activity
1.47	4.58e-02	GO:0005085	guanyl-nucleotide exchange factor activity
1.33	4.89e-02	GO:0003779	actin binding

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