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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: PAX6.p2

Z-value: 0.498

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_+_70646008	0.807	NM_001126102 NM_005143	HP	haptoglobin
chr16_+_70654625	0.583	NM_020995	HPR	haptoglobin-related protein
chr2_+_39000007	0.511	NM_001145451	ARHGEF33	Rho guanine nucleotide exchange factor (GEF) 33
chr4_-_174557191	0.498	NM_007281	SCRG1	stimulator of chondrogenesis 1
chr12_-_68379331	0.384	NM_032735	BEST3	bestrophin 3
chr9_+_102380156	0.372	NM_001018116	MURC	muscle-related coiled-coil protein
chr3_-_15538164	0.308	NM_005677 NM_080539	COLQ	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chrX_-_148604506	0.275	NM_001011544	MAGEA11	melanoma antigen family A, 11
chrX_+_2680092	0.270	NM_001141919 NM_001141920 NM_175569	XGPY2 XG	Xg pseudogene, Y-linked 2 Xg blood group
chr19_+_15920817	0.267	NM_001004465	OR10H4	olfactory receptor, family 10, subfamily H, member 4
chr6_+_155579788	0.262	NM_001010927	TIAM2	T-cell lymphoma invasion and metastasis 2
chr1_-_6502655	0.225	NM_198681	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr1_-_12830728	0.225	NM_001146181	HNRNPCL1 LOC649330	heterogeneous nuclear ribonucleoprotein C-like 1 heterogeneous nuclear ribonucleoprotein C-like
chr19_-_56825400	0.202	NM_003830	SIGLEC5	sialic acid binding Ig-like lectin 5
chr4_+_77575276	0.192	NM_020859	SHROOM3	shroom family member 3
chr16_-_46823682	0.190	NM_033151	ABCC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr12_-_131725848	0.190		POLE	polymerase (DNA directed), epsilon
chr19_-_14800275	0.187	NM_017506	OR7A5	olfactory receptor, family 7, subfamily A, member 5
chr5_+_79651545	0.186	NM_032567	SPZ1	spermatogenic leucine zipper 1
chrX_-_13745134	0.185		GPM6B	glycoprotein M6B
chr4_+_77829634	0.183		SHROOM3	shroom family member 3
chr2_-_171631728	0.181	NM_001136555	TLK1	tousled-like kinase 1
chr11_+_55776251	0.174	NM_001004747	OR5T3	olfactory receptor, family 5, subfamily T, member 3
chr4_-_26100986	0.168	NM_000730	CCKAR	cholecystokinin A receptor
chrX_-_138742050	0.165	NM_001010986 NM_173694	ATP11C	ATPase, class VI, type 11C
chrX_-_15242589	0.159	NM_001012428	ASB11	ankyrin repeat and SOCS box containing 11
chr15_-_48192804	0.155		ATP8B4	ATPase, class I, type 8B, member 4
chr5_-_141318810	0.155	NM_016580	PCDH12	protocadherin 12
chr10_-_82039158	0.154	NM_000429	MAT1A	methionine adenosyltransferase I, alpha
chr10_-_7699192	0.154		ITIH5	inter-alpha (globulin) inhibitor H5
chrX_-_52700674	0.139	NM_173358	SSX7	synovial sarcoma, X breakpoint 7
chr7_-_72761367	0.137		STX1A	syntaxin 1A (brain)
chr3_-_152585226	0.135	NM_022788	P2RY12	purinergic receptor P2Y, G-protein coupled, 12
chr11_-_58099884	0.130	NM_004811	LPXN	leupaxin
chr10_+_35934343	0.125	NM_153368	GJD4	gap junction protein, delta 4, 40.1kDa
chr11_+_19328846	0.124	NM_001111018	NAV2	neuron navigator 2
chr19_+_59941785	0.121	NM_015868	KIR2DS2 KIR2DL3	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
chr2_+_178893216	0.119	NM_145739	OSBPL6	oxysterol binding protein-like 6
chr1_+_35623688	0.115		ZMYM4	zinc finger, MYM-type 4
chr13_+_52500830	0.113	NM_006418	OLFM4	olfactomedin 4
chr12_+_55201854	0.109	NM_002898	RBMS2	RNA binding motif, single stranded interacting protein 2
chr1_-_54861656	0.106	NM_176782	FAM151A	family with sequence similarity 151, member A
chr16_-_11282595	0.105	NM_002761	PRM1	protamine 1
chr6_+_25760352	0.104	NM_006998	SCGN	secretagogin, EF-hand calcium binding protein
chr5_-_135259403	0.103	NM_000590	IL9	interleukin 9
chr3_-_58627509	0.102	NM_138805	FAM3D	family with sequence similarity 3, member D
chr4_-_170314382	0.100		SH3RF1	SH3 domain containing ring finger 1
chr1_+_93830106	0.098		LOC100129046	hypothetical LOC100129046
chr6_-_42270671	0.097	NM_002098	GUCA1B	guanylate cyclase activator 1B (retina)
chr5_-_125956996	0.097		ALDH7A1	aldehyde dehydrogenase 7 family, member A1
chr5_+_55182963	0.096	NM_139017	IL31RA	interleukin 31 receptor A
chr17_-_31528027	0.095	NM_001001417	TBC1D3B TBC1D3C TBC1D3G TBC1D3F	TBC1 domain family, member 3B TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3F
chr3_-_150533948	0.093	NM_001184723 NM_138786	TM4SF18	transmembrane 4 L six family member 18
chr13_-_109600709	0.092		COL4A1	collagen, type IV, alpha 1
chr11_+_111294868	0.092		C11orf52	chromosome 11 open reading frame 52
chr1_+_113038202	0.092		MOV10	Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_+_165564904	0.091	NM_001198783	POU2F1	POU class 2 homeobox 1
chrX_-_65176564	0.090	NM_001100431 NM_001184830 NM_001184831 NM_007268	VSIG4	V-set and immunoglobulin domain containing 4
chr2_+_170074457	0.088	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chr19_+_9064854	0.087	NM_001004456	OR1M1	olfactory receptor, family 1, subfamily M, member 1
chr10_+_18280773	0.086	NM_001145195 NM_152725	SLC39A12	solute carrier family 39 (zinc transporter), member 12
chr17_-_36294962	0.085	NM_019010	KRT20	keratin 20
chrX_-_13745234	0.084	NM_001001995 NM_001001996 NM_005278	GPM6B	glycoprotein M6B
chr1_+_246703249	0.084	NM_001005495	OR2T3	olfactory receptor, family 2, subfamily T, member 3
chr3_-_120861959	0.083	NM_022135	POPDC2	popeye domain containing 2
chr1_+_207944807	0.081	NM_005525	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1
chr16_-_71650034	0.080	NM_001164766	ZFHX3	zinc finger homeobox 3
chr3_+_16949585	0.078	NM_015184	PLCL2	phospholipase C-like 2
chr1_-_209732881	0.077	NM_001164688 NM_183059	RD3	retinal degeneration 3
chrX_+_103243762	0.075	NM_001143978	ZCCHC18	zinc finger, CCHC domain containing 18
chr1_-_246804680	0.075	NM_001001821	OR2T34	olfactory receptor, family 2, subfamily T, member 34
chr10_+_114033403	0.074	NM_058222	TECTB	tectorin beta
chr1_+_93830169	0.074		LOC100129046	hypothetical LOC100129046
chr8_-_7710547	0.065	NM_001037668 NM_001040705	DEFB107A DEFB107B	defensin, beta 107A defensin, beta 107B
chrX_-_130251068	0.062	NM_001170961 NM_001170962 NM_001555 NM_205833	IGSF1	immunoglobulin superfamily, member 1
chr17_-_31831093	0.061	NM_001123392 NM_032258	TBC1D3C TBC1D3G TBC1D3 TBC1D3H TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3H TBC1 domain family, member 3F
chr6_-_28591542	0.061	NM_182701	GPX6	glutathione peroxidase 6 (olfactory)
chr4_-_10295412	0.059	NM_052964	CLNK	cytokine-dependent hematopoietic cell linker
chr1_+_61697209	0.059		NFIA	nuclear factor I/A
chr20_+_31106797	0.058	NM_182658	C20orf185	chromosome 20 open reading frame 185
chrX_-_130250880	0.057		IGSF1	immunoglobulin superfamily, member 1
chrX_-_13745108	0.056		GPM6B	glycoprotein M6B
chr11_-_123130435	0.056	NM_001005188	OR6X1	olfactory receptor, family 6, subfamily X, member 1
chr6_-_50097606	0.054	NM_001037497 NM_001037728	DEFB110	defensin, beta 110 locus
chrX_+_48127911	0.053	NM_001034832 NM_001040612 NM_005636 NM_175729	SSX4B SSX4	synovial sarcoma, X breakpoint 4B synovial sarcoma, X breakpoint 4
chr6_-_152681171	0.053	NM_015293	SYNE1	spectrin repeat containing, nuclear envelope 1
chr12_+_10351683	0.052	NM_002262 NM_007334	KLRD1	killer cell lectin-like receptor subfamily D, member 1
chr6_-_131333173	0.051		EPB41L2	erythrocyte membrane protein band 4.1-like 2
chrX_+_52797004	0.049	NM_003147 NM_175698 NM_001164417	SSX2 SSX2B	synovial sarcoma, X breakpoint 2 synovial sarcoma, X breakpoint 2B
chr21_+_38566298	0.049	NM_170737	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr13_+_23742846	0.048		SPATA13	spermatogenesis associated 13
chr11_+_76561471	0.047		MYO7A	myosin VIIA
chr18_+_17076166	0.047	NM_001142966	GREB1L	growth regulation by estrogen in breast cancer-like
chr11_+_111294810	0.047	NM_080659	C11orf52	chromosome 11 open reading frame 52
chr3_-_14558591	0.045	NM_001080423	GRIP2	glutamate receptor interacting protein 2
chr1_+_145841569	0.043	NM_005267	GJA8	gap junction protein, alpha 8, 50kDa
chr2_-_138762909	0.043
chr17_-_8602601	0.042	NM_001128076	SPDYE4	speedy homolog E4 (Xenopus laevis)
chr16_+_52037186	0.042		RBL2	retinoblastoma-like 2 (p130)
chr7_+_45033757	0.042	NM_001029835	CCM2	cerebral cavernous malformation 2
chr10_-_79298876	0.041		DLG5	discs, large homolog 5 (Drosophila)
chr5_-_79982584	0.040	NM_001190470	MTRNR2L2	MT-RNR2-like 2
chr1_+_97033103	0.040
chr21_+_38550739	0.039	NM_170736	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr8_-_62764839	0.038	NM_001164750 NM_001164751 NM_001164752 NM_001164753 NM_020164 NM_032467 NM_032468	ASPH	aspartate beta-hydroxylase
chr15_+_27001131	0.037	NM_001130414 NM_005503	APBA2	amyloid beta (A4) precursor protein-binding, family A, member 2
chr17_-_33602374	0.037	NM_032258	TBC1D3C TBC1D3G TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3F
chr11_+_117452995	0.037		TMPRSS4	transmembrane protease, serine 4
chr2_+_119416214	0.037	NM_006770	MARCO	macrophage receptor with collagenous structure
chr5_+_147672181	0.036	NM_032566	SPINK7	serine peptidase inhibitor, Kazal type 7 (putative)
chr8_-_27525084	0.035	NM_001171138	CLU	clusterin
chr8_+_7340777	0.035	NM_001037668 NM_001040705	DEFB107A DEFB107B	defensin, beta 107A defensin, beta 107B
chr11_-_117252541	0.035		FXYD6	FXYD domain containing ion transport regulator 6
chrX_-_48156287	0.035	NM_001034832 NM_001040612 NM_005636 NM_175729	SSX4B SSX4	synovial sarcoma, X breakpoint 4B synovial sarcoma, X breakpoint 4
chr15_-_23204887	0.035	NM_000462	UBE3A	ubiquitin protein ligase E3A
chr1_-_13263334	0.034	NM_001012276	PRAMEF8 PRAMEF7	PRAME family member 8 PRAME family member 7
chr20_-_45360903	0.034		ZMYND8	zinc finger, MYND-type containing 8
chr12_-_55790355	0.034	NM_001178079	STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr3_-_196792059	0.034		APOD	apolipoprotein D
chr7_+_72913424	0.033	NM_182504	WBSCR28	Williams-Beuren syndrome chromosome region 28
chr5_-_114965959	0.033	NM_021649	TICAM2	toll-like receptor adaptor molecule 2
chrX_-_13744933	0.032		GPM6B	glycoprotein M6B
chr9_+_130485754	0.030	NM_001122821	SET	SET nuclear oncogene
chr11_-_11331411	0.030		CSNK2A1P	casein kinase 2, alpha 1 polypeptide pseudogene
chr8_-_93181091	0.030	NM_001198628	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr16_-_27806978	0.030	NM_144675	GSG1L	GSG1-like
chr12_-_69317441	0.029	NM_001109754	PTPRB	protein tyrosine phosphatase, receptor type, B
chr3_+_52212969	0.028		ALAS1	aminolevulinate, delta-, synthase 1
chr2_-_18634257	0.028	NM_001002006 NM_033253	NT5C1B-RDH14 NT5C1B	NT5C1B-RDH14 readthrough 5'-nucleotidase, cytosolic IB
chr1_+_78888064	0.028	NM_006417	IFI44	interferon-induced protein 44
chr10_-_45350804	0.028	NM_001002266	MARCH8	membrane-associated ring finger (C3HC4) 8
chr5_+_121493113	0.028	NM_207317	ZNF474	zinc finger protein 474
chr5_-_58918031	0.027	NM_006203	PDE4D	phosphodiesterase 4D, cAMP-specific
chr21_-_38792173	0.026	NM_001136155 NM_182918	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr9_+_122923864	0.025		CEP110	centrosomal protein 110kDa
chr15_+_63124760	0.025	NM_178859	OSTBETA	organic solute transporter beta
chr17_-_31616071	0.024	NM_001001418 NM_032258	TBC1D3B TBC1D3C TBC1D3G TBC1D3F	TBC1 domain family, member 3B TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3F
chrX_+_50670474	0.024	NM_005448	BMP15	bone morphogenetic protein 15
chr2_-_133256097	0.023		NCKAP5	NCK-associated protein 5
chr3_-_121117647	0.022		GSK3B	glycogen synthase kinase 3 beta
chr17_+_22982344	0.021		LGALS9	lectin, galactoside-binding, soluble, 9
chr8_+_18123456	0.020	NM_001160174	NAT1	N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr5_+_42792676	0.018	NM_001134848	CCDC152	coiled-coil domain containing 152
chr12_+_8557402	0.018	NM_080387	CLEC4D	C-type lectin domain family 4, member D
chrX_-_76823813	0.018
chr15_+_43331719	0.017	NM_004212	SLC28A2	solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
chr6_+_167624792	0.016	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr2_+_115538716	0.016	NM_001178037	DPP10	dipeptidyl-peptidase 10 (non-functional)
chr19_-_59019240	0.016	NM_144687	NLRP12	NLR family, pyrin domain containing 12
chr1_+_165565006	0.014		POU2F1	POU class 2 homeobox 1
chr6_-_31954795	0.014	NM_001178044 NM_025257	SLC44A4	solute carrier family 44, member 4
chr1_-_161105174	0.014	NM_178550	C1orf110	chromosome 1 open reading frame 110
chr21_-_30855478	0.013	NM_181614	KRTAP19-7	keratin associated protein 19-7
chr2_-_157890400	0.013	NM_020711	ERMN	ermin, ERM-like protein
chr12_+_108035424	0.013
chr7_-_26198673	0.013		HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1
chr17_-_33552166	0.013	NM_001123391 NM_032258	TBC1D3C TBC1D3G TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3F
chr19_+_56990222	0.013	NM_002030	FPR3	formyl peptide receptor 3
chr19_+_54299686	0.012		SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)
chr21_-_30510113	0.012	NM_199328	CLDN8	claudin 8
chr17_-_34209671	0.012	NM_003559	PIP4K2B	phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr12_+_18305740	0.012	NM_004570	PIK3C2G	phosphoinositide-3-kinase, class 2, gamma polypeptide
chr11_-_4827013	0.011	NM_001004758	OR51S1	olfactory receptor, family 51, subfamily S, member 1
chr1_+_202033273	0.011	NM_001174108	ZBED6	zinc finger, BED-type containing 6
chr4_+_100714995	0.011		MTTP	microsomal triglyceride transfer protein
chr17_+_22982372	0.010		LGALS9	lectin, galactoside-binding, soluble, 9
chr3_+_109498082	0.010		HHLA2	HERV-H LTR-associating 2
chr14_-_30927931	0.010	NM_015473	HEATR5A	HEAT repeat containing 5A
chr1_-_245902965	0.009	NM_001005487	OR13G1	olfactory receptor, family 13, subfamily G, member 1
chr4_+_89115825	0.009	NM_000582 NM_001040058 NM_001040060	SPP1	secreted phosphoprotein 1
chrX_+_92815667	0.009	NM_001171109 NM_001171110 NM_001171111 NM_173698	FAM133A	family with sequence similarity 133, member A
chr1_-_87152372	0.008		SEP15	15 kDa selenoprotein
chr12_-_43555607	0.008	NM_001145109	NELL2	NEL-like 2 (chicken)
chr17_+_8154280	0.008	NM_173728	ARHGEF15	Rho guanine nucleotide exchange factor (GEF) 15
chrX_-_84250629	0.007	NM_001012980	SATL1	spermidine/spermine N1-acetyl transferase-like 1
chr5_-_142795269	0.007	NM_001018074 NM_001018075 NM_001018077	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr14_-_87806913	0.007	NM_138318	KCNK10	potassium channel, subfamily K, member 10
chrX_+_49718954	0.007	NM_000084	CLCN5	chloride channel 5
chr19_-_62659665	0.006	NM_020633	VN1R1	vomeronasal 1 receptor 1
chr7_+_80105907	0.005		CD36	CD36 molecule (thrombospondin receptor)
chr2_+_214984705	0.004	NM_001080500	VWC2L	von Willebrand factor C domain containing protein 2-like
chr4_-_185963859	0.004		ACSL1	acyl-CoA synthetase long-chain family member 1
chr1_+_84382562	0.003		PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr11_+_834445	0.002	NM_001025237	TSPAN4	tetraspanin 4
chr5_-_169657312	0.002		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr3_+_153499883	0.001	NM_207293 NM_207294 NM_207295 NM_207296 NM_207297	MBNL1	muscleblind-like (Drosophila)
chr9_-_16860664	0.001		BNC2	basonuclin 2
chr12_-_43556220	0.001		NELL2	NEL-like 2 (chicken)
chr16_-_29514140	0.001
chr9_-_115901157	0.000	NM_138424	KIF12	kinesin family member 12

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
5.38	1.30e-03	GO:0046578	regulation of Ras protein signal transduction
12.46	4.42e-03	GO:0032313	regulation of Rab GTPase activity
12.46	4.42e-03	GO:0032483	regulation of Rab protein signal transduction

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
12.22	1.33e-03	GO:0005097	Rab GTPase activator activity
4.01	1.40e-02	GO:0005083	small GTPase regulator activity

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