Motif ID: PBX1.p2

Z-value: 0.965


Transcription factors associated with PBX1.p2:

Gene SymbolEntrez IDGene Name
PBX1 5087 pre-B-cell leukemia homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PBX1chr1_+_1627955380.638.5e-03Click!


Activity profile for motif PBX1.p2.

activity profile for motif PBX1.p2


Sorted Z-values histogram for motif PBX1.p2

Sorted Z-values for motif PBX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PBX1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_23008742 1.760 NGDN
neuroguidin, EIF4E binding protein
chr18_+_42780784 1.405 NM_031303
KATNAL2
katanin p60 subunit A-like 2
chr14_+_23008723 1.405 NM_001042635
NM_015514
NGDN

neuroguidin, EIF4E binding protein

chr6_-_27222556 1.381 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr12_+_21570457 1.291 NM_030572
C12orf39
chromosome 12 open reading frame 39
chr4_+_8935987 1.188 NM_001105662
USP17L2
USP17L6P
USP17
ubiquitin specific peptidase 17-like 2
ubiquitin specific peptidase 17-like 6 (pseudogene)
ubiquitin specific peptidase 17
chr4_+_8940733 1.036 NM_001105662
USP17L2
USP17L6P
USP17
ubiquitin specific peptidase 17-like 2
ubiquitin specific peptidase 17-like 6 (pseudogene)
ubiquitin specific peptidase 17
chr17_-_40594652 0.965


chr5_+_90711887 0.927 LOC100129716
hypothetical LOC100129716
chr10_+_69539255 0.901 NM_032578
MYPN
myopalladin
chr6_+_27222839 0.874 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr2_+_12774264 0.849 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr5_+_162797149 0.840 NM_004060
NM_199246
CCNG1

cyclin G1

chr7_+_133982070 0.814 NM_001724
NM_199186
BPGM

2,3-bisphosphoglycerate mutase

chr5_-_89741233 0.775 NM_004365
CETN3
centrin, EF-hand protein, 3
chr8_-_12033677 0.770 NM_201402
USP17L2
ubiquitin specific peptidase 17-like 2
chr13_-_32757835 0.733 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr17_+_43328514 0.726 NM_003110
SP2
Sp2 transcription factor
chr8_+_99145925 0.718 NM_001170806
NM_173549
C8orf47

chromosome 8 open reading frame 47

chr2_+_85676347 0.717 NM_016494
RNF181
ring finger protein 181
chr6_+_26307691 0.702 NM_003522
HIST1H2BF
histone cluster 1, H2bf
chr17_-_43977273 0.692 NM_002145
HOXB2
homeobox B2
chr6_+_160131472 0.683 NM_014161
MRPL18
mitochondrial ribosomal protein L18
chr17_+_56109940 0.679 NM_001099432
NM_017679
BCAS3

breast carcinoma amplified sequence 3

chr6_-_26343139 0.675 NM_005320
HIST1H1D
histone cluster 1, H1d
chr6_+_26232351 0.669 NM_003512
HIST1H2AC
histone cluster 1, H2ac
chr15_-_62460622 0.653 NM_001029989
NM_014736
KIAA0101

KIAA0101

chr2_+_20510312 0.645 NM_004040
RHOB
ras homolog gene family, member B
chr6_-_26232109 0.635 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr16_-_68346299 0.634 NM_014062
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr16_+_24459173 0.618 RBBP6
retinoblastoma binding protein 6
chr15_+_39032927 0.617 NM_001142776
NM_024111
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr3_+_173951163 0.613 ECT2
epithelial cell transforming sequence 2 oncogene
chr7_-_135083906 0.605 NM_205855
FAM180A
family with sequence similarity 180, member A
chr6_+_26212082 0.603 NM_003542
HIST1H4C
histone cluster 1, H4c
chr4_-_177950658 0.602 NM_005429
VEGFC
vascular endothelial growth factor C
chr17_+_53670785 0.593 NM_001160102
NM_006151
LPO

lactoperoxidase

chr16_-_3246587 0.591 NM_000243
NM_001198536
MEFV

Mediterranean fever

chr6_-_63053811 0.588 NM_152688
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr14_+_22860547 0.586 PABPN1
poly(A) binding protein, nuclear 1
chr1_+_162795328 0.585 NM_002585
PBX1
pre-B-cell leukemia homeobox 1
chr5_+_139999182 0.580 NM_018502
TMCO6
transmembrane and coiled-coil domains 6
chr1_+_16220952 0.576 NM_001042704
NM_004070
CLCNKA

CLCNKB
chloride channel Ka

chloride channel Kb
chr1_-_152162074 0.557 NM_020699
GATAD2B
GATA zinc finger domain containing 2B
chr13_+_94052022 0.552 NM_180989
GPR180
G protein-coupled receptor 180
chr6_+_26153590 0.541 NM_003531
HIST1H3C
histone cluster 1, H3c
chr6_-_26307418 0.535 NM_021065
NM_003530
HIST1H2AD
HIST1H3D
histone cluster 1, H2ad
histone cluster 1, H3d
chr12_-_28016182 0.522 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr2_+_183651713 0.521 DUSP19
dual specificity phosphatase 19
chr2_+_44249565 0.506 PPM1B
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr16_+_11346780 0.502 NM_152308
C16orf75
chromosome 16 open reading frame 75
chr6_+_111302679 0.501 NM_001634
NM_001033059
AMD1

adenosylmethionine decarboxylase 1

chr3_+_195336625 0.496 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr20_+_186376 0.488 NM_207469
DEFB132
defensin, beta 132
chr14_+_23654161 0.484 DCAF11
DDB1 and CUL4 associated factor 11
chr6_-_27943287 0.484 NM_005322
HIST1H1B
histone cluster 1, H1b
chr16_-_68880844 0.477 AARS
alanyl-tRNA synthetase
chr6_+_26381122 0.474 NM_003525
HIST1H2BI
histone cluster 1, H2bi
chr17_-_36074812 0.473 NM_152349
KRT222
keratin 222
chr3_-_53139457 0.473 NM_052859
RFT1
RFT1 homolog (S. cerevisiae)
chr16_-_68880908 0.466 NM_001605
AARS
alanyl-tRNA synthetase
chr4_-_140696740 0.462 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr17_-_41794825 0.453 NM_001039083
NM_001103154
ARL17A
ARL17B

ADP-ribosylation factor-like 17A
ADP-ribosylation factor-like 17B

chr2_-_183439515 0.451 NM_001463
FRZB
frizzled-related protein
chr14_+_22860511 0.450 PABPN1
poly(A) binding protein, nuclear 1
chr14_-_22722680 0.445 NM_012244
SLC7A8
solute carrier family 7 (amino acid transporter, L-type), member 8
chr17_-_43328141 0.444


chr10_-_108448990 0.441 SORCS1
sortilin-related VPS10 domain containing receptor 1
chr7_+_106596641 0.440 NM_012257
HBP1
HMG-box transcription factor 1
chr2_-_189752575 0.438 NM_000393
COL5A2
collagen, type V, alpha 2
chr20_+_18396030 0.437 NM_006466
POLR3F
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chr2_+_62786290 0.437 NM_001142616
NM_015252
EHBP1

EH domain binding protein 1

chr20_+_29790564 0.429 NM_012112
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr20_-_54400628 0.422 NM_003600
NM_198433
NM_198434
NM_198435
NM_198436
NM_198437
AURKA





aurora kinase A





chr9_+_91115924 0.420 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr12_-_56200547 0.419 NM_001195053
NM_001195054
NM_001195055
NM_001195056
NM_001195057
NM_004083
DDIT3





DNA-damage-inducible transcript 3





chr3_+_195336631 0.418 HES1
hairy and enhancer of split 1, (Drosophila)
chr2_-_211049619 0.416 NM_001136574
NM_006055
NM_001136575
LANCL1


LanC lantibiotic synthetase component C-like 1 (bacterial)


chr15_+_39363442 0.415 LOC729082
hypothetical LOC729082
chr2_+_183651531 0.410 NM_001142314
NM_080876
DUSP19

dual specificity phosphatase 19

chr12_+_27568311 0.410 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr16_+_11346812 0.408 C16orf75
chromosome 16 open reading frame 75
chr15_+_41597097 0.399 NM_002373
MAP1A
microtubule-associated protein 1A
chr14_-_68329407 0.397 NM_004926
ZFP36L1
zinc finger protein 36, C3H type-like 1
chr4_-_48477021 0.393 FRYL
FRY-like
chr22_-_37520049 0.392 DNAL4
dynein, axonemal, light chain 4
chr17_-_71174816 0.385 NM_004259
NM_001003715
NM_001003716
RECQL5


RecQ protein-like 5


chr22_+_38903825 0.383 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr10_+_124310170 0.382 NM_004406
NM_007329
NM_017579
DMBT1


deleted in malignant brain tumors 1


chr6_-_169395847 0.382 THBS2
thrombospondin 2
chr10_-_21847126 0.380


chr10_-_44794146 0.379 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr16_-_19440786 0.378 NM_016641
GDE1
glycerophosphodiester phosphodiesterase 1
chr1_+_13948518 0.373 PRDM2
PR domain containing 2, with ZNF domain
chr6_-_26358811 0.370 NM_021018
HIST1H3F
histone cluster 1, H3f
chrX_+_110252960 0.367 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr6_-_32892705 0.365 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr10_+_63331401 0.364 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr6_-_166960690 0.363 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr14_+_73621408 0.363 NM_001024674
LIN52
lin-52 homolog (C. elegans)
chr12_+_21059896 0.362 NM_001009562
LST-3TM12
organic anion transporter LST-3b
chr17_+_43539909 0.361 NM_152244
NM_013323
SNX11

sorting nexin 11

chr2_-_154043403 0.358 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr6_+_160103500 0.356 ACAT2
acetyl-CoA acetyltransferase 2
chr3_-_150422474 0.352 NM_000096
CP
ceruloplasmin (ferroxidase)
chr17_-_42012324 0.348 NM_001113738
NM_016632
NM_001039083
ARL17A

ARL17B
ADP-ribosylation factor-like 17A

ADP-ribosylation factor-like 17B
chr2_+_183651756 0.332 DUSP19
dual specificity phosphatase 19
chr17_+_43540124 0.330 SNX11
sorting nexin 11
chr6_-_166960649 0.328 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_+_109036431 0.328 NM_018061
PRPF38B
PRP38 pre-mRNA processing factor 38 (yeast) domain containing B
chr12_-_51233001 0.327 NM_033448
KRT71
keratin 71
chr11_+_95163457 0.319 CEP57
centrosomal protein 57kDa
chr2_+_218843358 0.316 NM_001077399
NM_015488
PNKD

paroxysmal nonkinesigenic dyskinesia

chr17_+_71174993 0.315 NM_013260
SAP30BP
SAP30 binding protein
chr3_-_46993225 0.315 NM_144716
CCDC12
coiled-coil domain containing 12
chr1_+_13948504 0.315 PRDM2
PR domain containing 2, with ZNF domain
chr20_-_13567529 0.312 NM_017714
TASP1
taspase, threonine aspartase, 1
chr16_+_18986721 0.304 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr16_+_67778441 0.303 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr4_-_48477038 0.298 NM_015030
FRYL
FRY-like
chr1_+_13948448 0.298 NM_001007257
PRDM2
PR domain containing 2, with ZNF domain
chr7_-_30510849 0.295 NM_024051
GGCT
gamma-glutamylcyclotransferase
chr6_-_46728188 0.294 NM_016593
CYP39A1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr10_-_101180191 0.293 NM_002079
GOT1
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
chr10_-_115923874 0.292 C10orf118
chromosome 10 open reading frame 118
chr5_+_176494690 0.292 NSD1
nuclear receptor binding SET domain protein 1
chr12_+_49728350 0.290 NM_001024668
NM_015416
LETMD1

LETM1 domain containing 1

chr16_+_18986417 0.288 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr1_-_17638797 0.288 NM_018715
RCC2
regulator of chromosome condensation 2
chr16_+_18986459 0.287 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr3_+_157343444 0.286 NM_003471
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr7_-_526005 0.285 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr14_+_64041257 0.283 ZBTB1
zinc finger and BTB domain containing 1
chr22_-_37520092 0.277 NM_005740
DNAL4
dynein, axonemal, light chain 4
chr21_-_33935883 0.276 NM_145858
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr5_-_171814026 0.276 NM_001017995
SH3PXD2B
SH3 and PX domains 2B
chr12_-_54150188 0.275 NM_001005499
OR6C70
olfactory receptor, family 6, subfamily C, member 70
chr1_-_42574116 0.275 NM_001198850
FOXJ3
forkhead box J3
chr14_-_35859545 0.274 NM_001144891
NM_016586
MBIP

MAP3K12 binding inhibitory protein 1

chr1_-_13546097 0.272 NM_001024661
NM_001099854
PRAMEF13
PRAMEF14
PRAME family member 13
PRAME family member 14
chr6_-_25679197 0.272


chr15_-_35179185 0.272 MEIS2
Meis homeobox 2
chr14_-_23653965 0.269 NRL
neural retina leucine zipper
chr2_-_88208650 0.268 NM_001443
FABP1
fatty acid binding protein 1, liver
chr7_-_121571472 0.266 NM_005763
AASS
aminoadipate-semialdehyde synthase
chr14_+_51025604 0.264 NM_001042481
FRMD6
FERM domain containing 6
chr16_-_15889947 0.263 NM_144600
C16orf63
chromosome 16 open reading frame 63
chr4_-_118226119 0.260 NM_152402
TRAM1L1
translocation associated membrane protein 1-like 1
chr3_+_112934016 0.259 NM_001134437
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr15_-_35178888 0.253 NM_172316
MEIS2
Meis homeobox 2
chr14_-_22722658 0.253 SLC7A8
solute carrier family 7 (amino acid transporter, L-type), member 8
chr18_+_45342398 0.252 NM_006033
LIPG
lipase, endothelial
chr17_-_71023221 0.252 NM_020753
CASKIN2
CASK interacting protein 2
chr20_+_18436525 0.249 SEC23B
Sec23 homolog B (S. cerevisiae)
chr2_+_27109341 0.242 TMEM214
transmembrane protein 214
chr12_+_63090008 0.242 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr18_+_12981329 0.239 NM_032142
CEP192
centrosomal protein 192kDa
chr6_+_135544170 0.239 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr12_+_52689062 0.238 NM_022658
HOXC8
homeobox C8
chr17_+_76133206 0.236 NM_001163034
NM_020761
RPTOR

regulatory associated protein of MTOR, complex 1

chr2_+_191453791 0.235 NM_014905
GLS
glutaminase
chr2_-_88707978 0.234 NM_004836
EIF2AK3
eukaryotic translation initiation factor 2-alpha kinase 3
chr17_+_38576707 0.233 NM_005899
NBR1
neighbor of BRCA1 gene 1
chr14_-_105804211 0.232 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr11_+_61647990 0.230 NM_001040694
NM_020238
INCENP

inner centromere protein antigens 135/155kDa

chr6_+_83834080 0.230 NM_015018
DOPEY1
dopey family member 1
chr3_-_71196696 0.230 FOXP1
forkhead box P1
chr8_-_108579270 0.229 NM_001146
ANGPT1
angiopoietin 1
chr12_+_64982542 0.228 NM_033647
HELB
helicase (DNA) B
chr15_+_91244422 0.228 NM_001042572
NM_001271
CHD2

chromodomain helicase DNA binding protein 2

chr3_+_161040343 0.225 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr2_-_97646758 0.225 ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr12_-_118799457 0.224 NM_007174
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr17_+_20970828 0.222 NM_015510
DHRS7B
dehydrogenase/reductase (SDR family) member 7B
chr16_-_74024750 0.221 NM_006324
CFDP1
craniofacial development protein 1
chr6_+_126143971 0.217 NCOA7
nuclear receptor coactivator 7
chr16_+_81218074 0.217 NM_001257
CDH13
cadherin 13, H-cadherin (heart)
chr20_-_5879036 0.214 NM_015939
TRMT6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr16_-_778375 0.213 NM_058192
RPUSD1
RNA pseudouridylate synthase domain containing 1
chr1_-_239749634 0.212 FH
fumarate hydratase
chr17_-_71023048 0.211 CASKIN2
CASK interacting protein 2
chr11_-_85074848 0.211 NM_152723
CCDC89
coiled-coil domain containing 89
chr15_+_91244563 0.211 CHD2
chromodomain helicase DNA binding protein 2
chr1_+_25629968 0.211 NM_018202
TMEM57
transmembrane protein 57
chr9_-_98421894 0.211 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr6_-_166960496 0.210 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr17_-_39333490 0.210 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr6_+_26473376 0.210 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr14_-_21172837 0.209 NM_001005466
OR10G2
olfactory receptor, family 10, subfamily G, member 2
chr5_-_58607673 0.208 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr10_+_96512447 0.206 NM_000769
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr20_+_18436548 0.205 NM_001172745
SEC23B
Sec23 homolog B (S. cerevisiae)
chr16_+_2593351 0.204 LOC652276
hypothetical LOC652276
chr17_-_36456949 0.203 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr5_-_171813960 0.200 SH3PXD2B
SH3 and PX domains 2B
chr11_-_61823078 0.200 NM_206998
SCGB1D4
secretoglobin, family 1D, member 4
chr2_+_27109249 0.199 NM_001083590
NM_017727
TMEM214

transmembrane protein 214

chr13_+_96726415 0.197 MBNL2
muscleblind-like 2 (Drosophila)
chr2_+_191453792 0.197 GLS
glutaminase
chr2_-_144994349 0.196 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
5.95 1.41e-08 GO:0065004 protein-DNA complex assembly
5.64 4.40e-08 GO:0071824 protein-DNA complex subunit organization
5.92 4.17e-07 GO:0006334 nucleosome assembly
5.62 1.07e-06 GO:0031497 chromatin assembly
4.65 2.13e-06 GO:0006333 chromatin assembly or disassembly
5.34 2.60e-06 GO:0034728 nucleosome organization
4.75 3.38e-06 GO:0006323 DNA packaging
2.89 3.46e-05 GO:0034622 cellular macromolecular complex assembly
4.08 5.45e-05 GO:0071103 DNA conformation change
2.17 1.77e-04 GO:0071844 cellular component assembly at cellular level
2.43 4.95e-04 GO:0034621 cellular macromolecular complex subunit organization
1.70 5.53e-04 GO:0006996 organelle organization
2.16 2.69e-03 GO:0051276 chromosome organization
2.74 4.32e-03 GO:0000280 nuclear division
2.74 4.32e-03 GO:0007067 mitosis
1.47 4.88e-03 GO:0071842 cellular component organization at cellular level
2.04 5.13e-03 GO:0065003 macromolecular complex assembly
1.82 5.17e-03 GO:0022607 cellular component assembly
2.66 7.31e-03 GO:0000087 M phase of mitotic cell cycle
2.65 7.79e-03 GO:0048285 organelle fission
1.90 1.07e-02 GO:0043933 macromolecular complex subunit organization
1.43 1.70e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.71 2.30e-02 GO:0044085 cellular component biogenesis
2.24 3.14e-02 GO:0000279 M phase

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
7.94 4.43e-09 GO:0000786 nucleosome
5.97 2.11e-08 GO:0032993 protein-DNA complex
1.61 2.25e-07 GO:0043228 non-membrane-bounded organelle
1.61 2.25e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.20 4.93e-07 GO:0043229 intracellular organelle
1.20 6.50e-07 GO:0043226 organelle
1.33 5.71e-06 GO:0044422 organelle part
1.15 8.75e-06 GO:0044424 intracellular part
1.33 1.05e-05 GO:0044446 intracellular organelle part
3.23 3.14e-05 GO:0000785 chromatin
2.36 3.34e-05 GO:0005694 chromosome
2.49 5.02e-05 GO:0044427 chromosomal part
1.13 5.93e-05 GO:0005622 intracellular
1.19 2.20e-04 GO:0043231 intracellular membrane-bounded organelle
1.18 2.51e-04 GO:0043227 membrane-bounded organelle
1.27 7.39e-04 GO:0005634 nucleus
1.97 2.86e-03 GO:0015630 microtubule cytoskeleton
1.46 5.28e-03 GO:0043233 organelle lumen
1.56 9.41e-03 GO:0005856 cytoskeleton
1.43 1.05e-02 GO:0031974 membrane-enclosed lumen
1.42 2.62e-02 GO:0070013 intracellular organelle lumen
1.15 3.72e-02 GO:0005737 cytoplasm

Nothing significant found in function category.