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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: POU2F1..3.p2

Z-value: 0.921

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_+_26232351	1.275	NM_003512	HIST1H2AC	histone cluster 1, H2ac
chr6_-_33016561	1.114	NM_002118	HLA-DMB	major histocompatibility complex, class II, DM beta
chr22_+_21407066	0.989
chr22_+_21370394	0.917		IGL@	immunoglobulin lambda locus
chr6_-_26232109	0.825	NM_003526	HIST1H2BG HIST1H2BC	histone cluster 1, H2bg histone cluster 1, H2bc
chr6_-_10523203	0.820		TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_+_26325124	0.812	NM_021052	HIST1H2AE	histone cluster 1, H2ae
chr6_+_26359805	0.794	NM_003524	HIST1H2BH	histone cluster 1, H2bh
chr22_+_21495273	0.780
chr17_+_60563963	0.731		RGS9	regulator of G-protein signaling 9
chr6_+_26266311	0.708	NM_021063 NM_138720	HIST1H2BD	histone cluster 1, H2bd
chr6_-_10523424	0.705	NM_003220	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr17_+_19999784	0.705	NM_001033554 NM_001033555	SPECC1	sperm antigen with calponin homology and coiled-coil domains 1
chr6_-_168222645	0.679	NM_024919	FRMD1	FERM domain containing 1
chr22_+_21094094	0.676
chr11_-_11331411	0.659		CSNK2A1P	casein kinase 2, alpha 1 polypeptide pseudogene
chr1_+_154386358	0.651	NM_001193301	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr6_-_27222556	0.650	NM_080593	HIST1H2BK	histone cluster 1, H2bk
chr22_+_21116283	0.641
chr1_-_153098811	0.640	NM_170782	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr16_-_73365975	0.639		FA2H	fatty acid 2-hydroxylase
chr22_+_31080871	0.625	NM_006604	RFPL3	ret finger protein-like 3
chr22_+_20899155	0.619
chr5_+_2805261	0.619	NM_178569	C5orf38	chromosome 5 open reading frame 38
chr6_+_155579788	0.617	NM_001010927	TIAM2	T-cell lymphoma invasion and metastasis 2
chr14_+_22422270	0.611	NM_173527	REM2	RAS (RAD and GEM)-like GTP binding 2
chr22_+_20316968	0.607	NM_152612	CCDC116	coiled-coil domain containing 116
chr6_-_89984214	0.581	NM_002042	GABRR1	gamma-aminobutyric acid (GABA) receptor, rho 1
chr1_+_202000906	0.576	NM_001136190 NM_017773	LAX1	lymphocyte transmembrane adaptor 1
chr22_+_21042091	0.569		IGLV1-44 IGL@	immunoglobulin lambda variable 1-44 immunoglobulin lambda locus
chr22_+_21340757	0.568
chr6_-_26324850	0.568	NM_003518	HIST1H2BG NCALD	histone cluster 1, H2bg neurocalcin delta
chr16_-_73366200	0.564	NM_024306	FA2H	fatty acid 2-hydroxylase
chr10_-_98021144	0.538	NM_001114094 NM_013314	BLNK	B-cell linker
chr15_+_76171981	0.537	NM_001101404	SH2D7	SH2 domain containing 7
chr16_+_84202515	0.531	NM_001134473	KIAA0182	KIAA0182
chr17_+_60563917	0.527	NM_001081955 NM_001165933 NM_003835	RGS9	regulator of G-protein signaling 9
chr19_+_45996881	0.523	NM_080732	EGLN2	egl nine homolog 2 (C. elegans)
chr6_-_143307976	0.513	NM_006734	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2
chr12_+_91620749	0.510	NM_001037671 NM_001178097	C12orf74	chromosome 12 open reading frame 74
chr6_+_27208763	0.504	NM_021064	HIST1H2AG	histone cluster 1, H2ag
chr2_+_96790298	0.504	NM_020184	CNNM4	cyclin M4
chr5_-_73972055	0.491		ENC1	ectodermal-neural cortex 1 (with BTB-like domain)
chr6_-_53121540	0.485	NM_003643	GCM1	glial cells missing homolog 1 (Drosophila)
chr21_+_38566298	0.480	NM_170737	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr6_+_25834983	0.477	NM_170610	HIST1H2BA	histone cluster 1, H2ba
chr22_+_21384862	0.477		IGLV3-21 IGLJ3 IGLC1	immunoglobulin lambda variable 3-21 immunoglobulin lambda joining 3 immunoglobulin lambda constant 1 (Mcg marker)
chr5_-_2804768	0.467	NM_001134222 NM_033267	IRX2	iroquois homeobox 2
chr4_-_186970366	0.463	NM_003603 NM_001145670	SORBS2	sorbin and SH3 domain containing 2
chr19_+_45996940	0.457		EGLN2	egl nine homolog 2 (C. elegans)
chr3_+_153074118	0.455	NM_033050	SUCNR1	succinate receptor 1
chr19_-_48815853	0.446	NM_182498	ZNF428	zinc finger protein 428
chr6_+_26291936	0.444	NM_003523	HIST1H2BE	histone cluster 1, H2be
chr22_+_20715340	0.441
chr16_+_23754822	0.440		PRKCB	protein kinase C, beta
chr4_-_40212670	0.438	NM_019027	RBM47	RNA binding motif protein 47
chr17_-_45427565	0.437	NM_005220	DLX3	distal-less homeobox 3
chr22_+_21006814	0.421
chr16_+_23754860	0.413		PRKCB	protein kinase C, beta
chr1_+_204797079	0.411	NM_182665	RASSF5	Ras association (RalGDS/AF-6) domain family member 5
chr14_-_105862080	0.410		IGHV4-31 IGHA1 IGHD IGHG1 IGHG2 IGHG3 IGHM SCFV	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 2 (G2m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu single-chain Fv fragment
chr6_-_27208507	0.404	NM_021058	HIST1H2BJ	histone cluster 1, H2bj
chr6_-_56515640	0.403
chr20_-_48980858	0.400	NM_015339 NM_181442	ADNP	activity-dependent neuroprotector homeobox
chr3_+_114733907	0.399	NM_017699	SIDT1	SID1 transmembrane family, member 1
chr5_+_36644187	0.398	NM_001166695	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_42738535	0.396		TMSB4XP1	thymosin beta 4, X-linked pseudogene 1
chr9_-_126573349	0.394	NM_001489 NM_033334	NR6A1	nuclear receptor subfamily 6, group A, member 1
chr6_+_34312906	0.393		HMGA1	high mobility group AT-hook 1
chr22_+_20880159	0.392		IGLV6-57	immunoglobulin lambda variable 6-57
chr12_+_14409875	0.392	NM_018179	ATF7IP	activating transcription factor 7 interacting protein
chr6_+_37245860	0.389	NM_002648	PIM1	pim-1 oncogene
chr6_-_11887265	0.380	NM_001143948 NM_032744	C6orf105	chromosome 6 open reading frame 105
chr14_-_23623657	0.379	NM_006177	NRL	neural retina leucine zipper
chr6_-_170442090	0.378
chr1_+_165564904	0.378	NM_001198783	POU2F1	POU class 2 homeobox 1
chr22_+_20880112	0.378
chr6_+_34312667	0.370		HMGA1	high mobility group AT-hook 1
chr1_+_165565006	0.369		POU2F1	POU class 2 homeobox 1
chr6_-_25834733	0.364	NM_170745	HIST1H2AA	histone cluster 1, H2aa
chr19_+_40541327	0.363	NM_005304	FFAR3	free fatty acid receptor 3
chr16_+_23754997	0.362		PRKCB	protein kinase C, beta
chr7_+_111908143	0.359	NM_001134468 NM_182597	C7orf53	chromosome 7 open reading frame 53
chr2_-_113310796	0.356	NM_000576	IL1B	interleukin 1, beta
chr8_+_56954953	0.355		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr12_-_54646061	0.348	NM_006928	PMEL	premelanosome protein
chr21_+_29322100	0.344		USP16	ubiquitin specific peptidase 16
chr13_-_35327798	0.341	NM_001195415 NM_001195416 NM_001195430	DCLK1	doublecortin-like kinase 1
chr1_-_2447848	0.337	NM_018216	PANK4	pantothenate kinase 4
chr14_-_19252330	0.331	NM_001197287	OR11H2	olfactory receptor, family 11, subfamily H, member 2
chr3_+_122794859	0.331	NM_016298	FBXO40	F-box protein 40
chr6_-_26141774	0.327	NM_003513	HIST1H2AB	histone cluster 1, H2ab
chr15_+_78520634	0.322		ARNT2	aryl-hydrocarbon receptor nuclear translocator 2
chr6_+_20510019	0.318	NM_001949	E2F3	E2F transcription factor 3
chr1_+_204797120	0.315		RASSF5	Ras association (RalGDS/AF-6) domain family member 5
chr17_-_53849929	0.306	NM_017763	RNF43	ring finger protein 43
chr3_+_99733432	0.306	NM_005290	GPR15	G protein-coupled receptor 15
chr16_+_23754772	0.304	NM_002738 NM_212535	PRKCB	protein kinase C, beta
chr17_+_54997667	0.303	NM_001166301 NM_024612	DHX40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr3_+_187917791	0.301	NM_000893 NM_001102416 NM_001166451	KNG1	kininogen 1
chr22_+_21543671	0.300		IGLV4-3	immunoglobulin lambda variable 4-3
chr16_-_57309625	0.300		GOT2	glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
chr6_+_27969181	0.294	NM_003527	HIST1H2BO	histone cluster 1, H2bo
chr6_+_34313007	0.292		HMGA1	high mobility group AT-hook 1
chr20_+_32755778	0.290	NM_021202	TP53INP2	tumor protein p53 inducible nuclear protein 2
chr10_+_106103503	0.288	NM_001008723	CCDC147	coiled-coil domain containing 147
chr1_+_32311084	0.286	NM_018056	TMEM39B	transmembrane protein 39B
chr1_+_32311108	0.286		TMEM39B	transmembrane protein 39B
chr6_+_53043729	0.284	NM_012347	FBXO9	F-box protein 9
chr16_-_87280380	0.282	NM_178310	SNAI3	snail homolog 3 (Drosophila)
chr7_-_112514990	0.282		GPR85	G protein-coupled receptor 85
chr10_-_62002672	0.282		ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr22_+_21065134	0.281		LOC100290481	immunoglobulin lambda light chain-like
chr17_-_16816113	0.280	NM_012452	TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B
chr17_-_53849888	0.278		RNF43	ring finger protein 43
chr6_+_34312979	0.277		HMGA1	high mobility group AT-hook 1
chr6_-_128263868	0.273	NM_001010923 NM_001164685	THEMIS	thymocyte selection associated
chr17_-_34575939	0.271	NM_001143968	ARL5C	ADP-ribosylation factor-like 5C
chr6_+_27222839	0.263	NM_080596	HIST1H2AH	histone cluster 1, H2ah
chr17_+_24394281	0.260		PIPOX	pipecolic acid oxidase
chr5_+_73145098	0.257		RGNEF	190 kDa guanine nucleotide exchange factor
chr1_+_200246370	0.257		ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr7_-_112515068	0.257	NM_001146265 NM_018970	GPR85	G protein-coupled receptor 85
chr5_-_66528330	0.255	NM_005582	CD180	CD180 molecule
chr11_-_34336102	0.252	NM_145804	ABTB2	ankyrin repeat and BTB (POZ) domain containing 2
chr8_+_56954946	0.251		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr1_-_6537139	0.251		NOL9	nucleolar protein 9
chr22_+_21065202	0.250
chr22_+_21065207	0.249		IGLJ3	immunoglobulin lambda joining 3
chr6_+_139136349	0.244	NM_015439	CCDC28A	coiled-coil domain containing 28A
chr2_-_206790871	0.244	NM_001098199 NM_005279	GPR1	G protein-coupled receptor 1
chr7_-_112515035	0.242		GPR85	G protein-coupled receptor 85
chr8_+_56954899	0.237	NM_001111097 NM_002350	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr16_-_87280289	0.236		SNAI3	snail homolog 3 (Drosophila)
chr1_+_200246312	0.236	NM_001114309 NM_004433	ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr9_+_128716867	0.236	NM_001190729 NM_001190730 NM_014636	RALGPS1	Ral GEF with PH domain and SH3 binding motif 1
chr12_-_47250069	0.236	NM_002289	LALBA	lactalbumin, alpha-
chr14_-_105644300	0.232		IGHV4-31 IGHA1 IGHA2 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr8_+_123863169	0.228		ZHX2	zinc fingers and homeoboxes 2
chr5_-_16561936	0.227	NM_019000	FAM134B	family with sequence similarity 134, member B
chr19_+_14554895	0.223	NM_207390	CLEC17A	C-type lectin domain family 17, member A
chr6_+_21701942	0.222	NM_003107	SOX4	SRY (sex determining region Y)-box 4
chr12_+_52653176	0.220	NM_014212	HOXC11	homeobox C11
chr1_-_181889070	0.219	NM_203454	APOBEC4	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr9_-_94226380	0.219	NM_005014	OMD	osteomodulin
chr12_-_11066436	0.217	NM_176888	TAS2R19	taste receptor, type 2, member 19
chr20_+_62266217	0.217		MYT1	myelin transcription factor 1
chr2_-_172458970	0.213	NM_003705	SLC25A12	solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr15_+_65245546	0.213	NM_001145104	SMAD3	SMAD family member 3
chr11_-_62115545	0.211	NM_022830	TUT1	terminal uridylyl transferase 1, U6 snRNA-specific
chr6_+_41118214	0.210	NM_001010873 NM_001159726	TSPO2	translocator protein 2
chr1_+_201711505	0.210	NM_002725 NM_201348	PRELP	proline/arginine-rich end leucine-rich repeat protein
chr7_+_100021862	0.206	NM_033506	FBXO24	F-box protein 24
chr1_-_6537171	0.203	NM_024654	NOL9	nucleolar protein 9
chr7_-_102576570	0.202	NM_001122838 NM_198990	NAPEPLD	N-acyl phosphatidylethanolamine phospholipase D
chr6_-_26151863	0.201	NM_021062	HIST1H2BB	histone cluster 1, H2bb
chr16_+_10878539	0.200	NM_000246	CIITA	class II, major histocompatibility complex, transactivator
chr12_-_55730125	0.198	NM_005379	MYO1A	myosin IA
chr9_+_108726257	0.198		ZNF462	zinc finger protein 462
chr19_-_18253413	0.198	NM_005354	JUND	jun D proto-oncogene
chr12_-_31370387	0.194	NM_001135811 NM_021238 NM_001135812	FAM60A	family with sequence similarity 60, member A
chr4_-_91979113	0.193	NM_183049	TMSL3	thymosin-like 3
chr19_-_45253947	0.190	NM_001005851	ZNF780B	zinc finger protein 780B
chr10_-_64246129	0.190	NM_000399 NM_001136177 NM_001136179	EGR2	early growth response 2
chr6_-_11340887	0.188	NM_006403 NM_182966	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr20_-_60415729	0.187	NM_031215	CABLES2	Cdk5 and Abl enzyme substrate 2
chr14_+_18447521	0.187	NM_001013354	OR11H12	olfactory receptor, family 11, subfamily H, member 12
chr7_-_27206249	0.186	NM_000522	HOXA13	homeobox A13
chr2_-_175170674	0.183		WIPF1	WAS/WASL interacting protein family, member 1
chr10_-_64246080	0.183		EGR2	early growth response 2
chr12_-_55614311	0.182	NM_148897	SDR9C7	short chain dehydrogenase/reductase family 9C, member 7
chr20_-_39680405	0.181	NM_032221	CHD6	chromodomain helicase DNA binding protein 6
chr4_-_170314382	0.180		SH3RF1	SH3 domain containing ring finger 1
chr14_-_33489708	0.180	NM_022073	EGLN3	egl nine homolog 3 (C. elegans)
chr5_+_140730014	0.179	NM_018924 NM_032097	PCDHGB3	protocadherin gamma subfamily B, 3
chr6_-_170441493	0.179	NM_005618	DLL1	delta-like 1 (Drosophila)
chr17_-_38529638	0.179	NM_007298	BRCA1	breast cancer 1, early onset
chr11_+_27019084	0.178	NM_003986	BBOX1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr6_+_34312641	0.178		HMGA1	high mobility group AT-hook 1
chr22_-_41340886	0.177	NM_032311 NM_178136	POLDIP3	polymerase (DNA-directed), delta interacting protein 3
chr6_-_11340886	0.176		NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr5_-_64813459	0.175	NM_197941	ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr17_-_44249379	0.175	NM_001130918	TTLL6	tubulin tyrosine ligase-like family, member 6
chrX_-_55037235	0.175	NM_002625	PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr5_-_142045770	0.174	NM_000800	FGF1	fibroblast growth factor 1 (acidic)
chr17_-_30783631	0.174	NM_018042	SLFN12	schlafen family member 12
chr4_-_74307637	0.173		ANKRD17	ankyrin repeat domain 17
chr22_-_41340781	0.173		POLDIP3	polymerase (DNA-directed), delta interacting protein 3
chr6_-_11340869	0.171		NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr3_-_52688768	0.169	NM_018165 NM_181042	PBRM1	polybromo 1
chr8_+_123863224	0.168		ZHX2	zinc fingers and homeoboxes 2
chr1_+_201711578	0.167		PRELP	proline/arginine-rich end leucine-rich repeat protein
chr22_-_22426551	0.167	NM_013378	VPREB3	pre-B lymphocyte 3
chr2_+_54638957	0.166	NM_178313	SPTBN1	spectrin, beta, non-erythrocytic 1
chr8_+_123863075	0.165	NM_014943	ZHX2	zinc fingers and homeoboxes 2
chr12_-_120725210	0.164		LOC338799	hypothetical LOC338799
chr2_-_152393209	0.161	NM_001037174 NM_012097 NM_177985	ARL5A	ADP-ribosylation factor-like 5A
chr18_-_45271938	0.160		RPL17-C18ORF32 RPL17	RPL17-C18orf32 read-through transcript ribosomal protein L17
chr3_-_48569213	0.160	NM_004567	PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr1_-_148050534	0.160	NM_001024599 NM_001161334	HIST2H2BF	histone cluster 2, H2bf

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
6.33	5.09e-10	GO:0006333	chromatin assembly or disassembly
7.04	5.32e-10	GO:0071824	protein-DNA complex subunit organization
7.37	7.11e-10	GO:0034728	nucleosome organization
7.78	8.92e-10	GO:0006334	nucleosome assembly
7.10	1.56e-09	GO:0065004	protein-DNA complex assembly
7.38	2.53e-09	GO:0031497	chromatin assembly
5.65	4.16e-07	GO:0006323	DNA packaging
5.10	1.06e-06	GO:0071103	DNA conformation change
3.03	1.27e-06	GO:0034621	cellular macromolecular complex subunit organization
3.09	1.28e-06	GO:0006325	chromatin organization
3.18	2.77e-05	GO:0034622	cellular macromolecular complex assembly
1.61	1.28e-04	GO:0071841	cellular component organization or biogenesis at cellular level
2.51	1.50e-04	GO:0051276	chromosome organization
1.61	2.57e-04	GO:0071842	cellular component organization at cellular level
2.21	1.51e-03	GO:0006955	immune response
7.57	2.92e-03	GO:0050909	sensory perception of taste
1.86	3.21e-03	GO:0002376	immune system process
1.73	3.64e-03	GO:0006996	organelle organization
2.07	1.62e-02	GO:0071844	cellular component assembly at cellular level
2.00	1.81e-02	GO:0043933	macromolecular complex subunit organization
2.04	4.89e-02	GO:0065003	macromolecular complex assembly

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
10.50	7.31e-12	GO:0000786	nucleosome
4.81	6.51e-11	GO:0000785	chromatin
6.71	2.76e-08	GO:0032993	protein-DNA complex
2.74	1.34e-06	GO:0005694	chromosome
2.78	1.43e-05	GO:0044427	chromosomal part
1.56	9.31e-05	GO:0043228	non-membrane-bounded organelle
1.56	9.31e-05	GO:0043232	intracellular non-membrane-bounded organelle
1.35	1.99e-02	GO:0032991	macromolecular complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
9.94	1.97e-06	GO:0003823	antigen binding
1.47	1.79e-02	GO:0003677	DNA binding

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