Motif ID: POU2F1..3.p2

Z-value: 0.921


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU2F2chr19_-_473283990.562.3e-02Click!
POU2F1chr1_+_165456572-0.312.4e-01Click!
POU2F3chr11_+_119616112-0.204.5e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_26232351 1.275 NM_003512
 HIST1H2AC
histone cluster 1, H2ac
chr6_-_33016561 1.114 NM_002118
 HLA-DMB
major histocompatibility complex, class II, DM beta
chr22_+_21407066 0.989


chr22_+_21370394 0.917 IGL@
immunoglobulin lambda locus
chr6_-_26232109 0.825 NM_003526
 HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr6_-_10523203 0.820 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_+_26325124 0.812 NM_021052
 HIST1H2AE
histone cluster 1, H2ae
chr6_+_26359805 0.794 NM_003524
 HIST1H2BH
histone cluster 1, H2bh
chr22_+_21495273 0.780


chr17_+_60563963 0.731 RGS9
regulator of G-protein signaling 9
chr6_+_26266311 0.708 NM_021063
NM_138720
 HIST1H2BD

histone cluster 1, H2bd

chr6_-_10523424 0.705 NM_003220
 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr17_+_19999784 0.705 NM_001033554
NM_001033555
 SPECC1

sperm antigen with calponin homology and coiled-coil domains 1

chr6_-_168222645 0.679 NM_024919
 FRMD1
FERM domain containing 1
chr22_+_21094094 0.676


chr11_-_11331411 0.659 CSNK2A1P
casein kinase 2, alpha 1 polypeptide pseudogene
chr1_+_154386358 0.651 NM_001193301
 SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr6_-_27222556 0.650 NM_080593
 HIST1H2BK
histone cluster 1, H2bk
chr22_+_21116283 0.641


chr1_-_153098811 0.640 NM_170782
 KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
7.78 8.92e-10 GO:0006334 nucleosome assembly
7.57 2.92e-03 GO:0050909 sensory perception of taste
7.38 2.53e-09 GO:0031497 chromatin assembly
7.37 7.11e-10 GO:0034728 nucleosome organization
7.10 1.56e-09 GO:0065004 protein-DNA complex assembly
7.04 5.32e-10 GO:0071824 protein-DNA complex subunit organization
6.33 5.09e-10 GO:0006333 chromatin assembly or disassembly
5.65 4.16e-07 GO:0006323 DNA packaging
5.10 1.06e-06 GO:0071103 DNA conformation change
3.18 2.77e-05 GO:0034622 cellular macromolecular complex assembly
3.09 1.28e-06 GO:0006325 chromatin organization
3.03 1.27e-06 GO:0034621 cellular macromolecular complex subunit organization
2.51 1.50e-04 GO:0051276 chromosome organization
2.21 1.51e-03 GO:0006955 immune response
2.07 1.62e-02 GO:0071844 cellular component assembly at cellular level
2.04 4.89e-02 GO:0065003 macromolecular complex assembly
2.00 1.81e-02 GO:0043933 macromolecular complex subunit organization
1.86 3.21e-03 GO:0002376 immune system process
1.73 3.64e-03 GO:0006996 organelle organization
1.61 1.28e-04 GO:0071841 cellular component organization or biogenesis at cellular level

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
10.50 7.31e-12 GO:0000786 nucleosome
6.71 2.76e-08 GO:0032993 protein-DNA complex
4.81 6.51e-11 GO:0000785 chromatin
2.78 1.43e-05 GO:0044427 chromosomal part
2.74 1.34e-06 GO:0005694 chromosome
1.56 9.31e-05 GO:0043228 non-membrane-bounded organelle
1.56 9.31e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.35 1.99e-02 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
9.94 1.97e-06 GO:0003823 antigen binding
1.47 1.79e-02 GO:0003677 DNA binding