Motif ID: POU3F1..4.p2

Z-value: 1.228


Transcription factors associated with POU3F1..4.p2:

Gene SymbolEntrez IDGene Name
POU3F1 5453 POU class 3 homeobox 1
POU3F2 5454 POU class 3 homeobox 2
POU3F3 5455 POU class 3 homeobox 3
POU3F4 5456 POU class 3 homeobox 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU3F2chr6_+_993893000.371.6e-01Click!
POU3F3chr2_+_1048381770.253.5e-01Click!
POU3F1chr1_-_38285033-0.117.0e-01Click!
POU3F4chrX_+_826499240.087.6e-01Click!


Activity profile for motif POU3F1..4.p2.

activity profile for motif POU3F1..4.p2


Sorted Z-values histogram for motif POU3F1..4.p2

Sorted Z-values for motif POU3F1..4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU3F1..4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_66570683 1.541 PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_+_150065732 1.357 NM_001870
 CPA3
carboxypeptidase A3 (mast cell)
chr12_+_54172413 1.250 NM_001005519
 OR6C68
olfactory receptor, family 6, subfamily C, member 68
chr3_+_12367993 1.246 NM_015869
 PPARG
peroxisome proliferator-activated receptor gamma
chr10_-_51678318 1.202 NM_001143974
NM_019893
 ASAH2

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

chr11_+_113280727 1.044 NM_006028
 HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr2_-_180319013 0.998 NM_001113397
 ZNF385B
zinc finger protein 385B
chr1_+_176577228 0.916 NM_004841
 RASAL2
RAS protein activator like 2
chr7_+_20621769 0.906 NM_001163941
 ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chrX_-_15530112 0.825 NM_021804
 ACE2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr1_+_184532027 0.807 NM_001127708
NM_001127709
NM_001127710
NM_005807
 PRG4



proteoglycan 4



chr8_-_20084892 0.765 NM_001135691
NM_001142324
NM_001142325
NM_003053
 SLC18A1



solute carrier family 18 (vesicular monoamine), member 1



chr6_+_24465109 0.757 NM_181337
 KAAG1
kidney associated antigen 1
chr6_+_49575629 0.755 NM_001010904
 GLYATL3
glycine-N-acyltransferase-like 3
chr11_-_35235325 0.741 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_+_151922350 0.740 NM_007115
 TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr2_+_135312655 0.731 NM_138326
 ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr12_-_94469357 0.697 NM_032147
 USP44
ubiquitin specific peptidase 44
chr12_-_90029328 0.689 LUM
lumican
chr3_-_152529999 0.660 NM_176894
 P2RY13
purinergic receptor P2Y, G-protein coupled, 13

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.89 4.21e-09 GO:0007606 sensory perception of chemical stimulus
2.87 9.18e-08 GO:0007608 sensory perception of smell
2.16 2.04e-06 GO:0007600 sensory perception
1.87 1.87e-06 GO:0050877 neurological system process
1.78 6.27e-07 GO:0003008 system process
1.31 1.42e-05 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
4.84 1.42e-03 GO:0031091 platelet alpha granule
4.50 1.69e-02 GO:0031983 vesicle lumen
4.48 4.07e-02 GO:0031093 platelet alpha granule lumen
4.39 4.82e-02 GO:0034774 secretory granule lumen
1.71 1.35e-02 GO:0005626 insoluble fraction
1.68 3.67e-02 GO:0005624 membrane fraction
1.55 6.78e-13 GO:0071944 cell periphery
1.55 1.50e-12 GO:0005886 plasma membrane
1.31 2.84e-05 GO:0016021 integral to membrane
1.30 3.53e-05 GO:0031224 intrinsic to membrane
1.28 5.36e-06 GO:0044425 membrane part
1.25 2.40e-06 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
6.55 2.84e-02 GO:0001608 nucleotide receptor activity, G-protein coupled
6.55 2.84e-02 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled
2.95 1.49e-08 GO:0004984 olfactory receptor activity
2.50 3.28e-12 GO:0004930 G-protein coupled receptor activity
2.02 2.07e-09 GO:0004888 transmembrane receptor activity
1.92 9.37e-11 GO:0004872 receptor activity
1.81 9.69e-11 GO:0004871 signal transducer activity
1.81 9.69e-11 GO:0060089 molecular transducer activity