Motif ID: POU5F1.p2

Z-value: 1.640


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_312425930.562.4e-02Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_16649211 4.014 LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_-_110443247 3.354 NM_032518
NM_198721
COL25A1

collagen, type XXV, alpha 1

chr2_+_5750229 2.694 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr10_+_68355797 2.676 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr15_+_26832300 2.540 LOC100289656
Dexi homolog (mouse) pseudogene
chr13_-_101852028 2.476 NM_175929
FGF14
fibroblast growth factor 14
chr17_-_33178987 2.475 HNF1B
HNF1 homeobox B
chr11_-_3620060 2.444 NM_053017
NM_001079536
ART5

ADP-ribosyltransferase 5

chr13_-_52320774 2.425 NM_002590
NM_032949
PCDH8

protocadherin 8

chrX_-_6156655 2.421 NM_181332
NLGN4X
neuroligin 4, X-linked
chr13_-_60887210 2.301 PCDH20
protocadherin 20
chr17_+_7494964 2.294 NM_001678
ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr17_+_7495140 2.185 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr4_+_158361185 2.078 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chrX_-_33267646 2.053 NM_000109
DMD
dystrophin
chr4_-_41445479 1.999 PHOX2B
paired-like homeobox 2b
chr17_-_33179118 1.955 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr4_+_41395493 1.949 LIMCH1
LIM and calponin homology domains 1
chr6_+_105511615 1.932 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr15_-_86600658 1.816 NM_001007156
NM_001012338
NM_002530
NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr1_-_214963279 1.744 NM_001438
ESRRG
estrogen-related receptor gamma
chr17_-_44047299 1.738 NM_024016
HOXB8
homeobox B8
chr10_+_124897627 1.670 NM_005519
HMX2
H6 family homeobox 2
chr11_-_31789360 1.659 PAX6
paired box 6
chr14_-_56342097 1.640 NM_172337
OTX2
orthodenticle homeobox 2
chr1_-_215329569 1.580 NM_206594
NM_206595
ESRRG

estrogen-related receptor gamma

chr1_-_147665783 1.571 HIST2H2BF
histone cluster 2, H2bf
chr8_-_25958556 1.550 EBF2
early B-cell factor 2
chr1_-_175400573 1.514 NM_004319
NM_207108
ASTN1

astrotactin 1

chr6_+_50789215 1.510 NM_172238
TFAP2D
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr3_+_174598937 1.501 NM_014932
NLGN1
neuroligin 1
chr3_+_129124591 1.476 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr11_-_31789334 1.466 PAX6
paired box 6
chr17_+_7495436 1.439 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr14_+_61532293 1.399 NM_031914
SYT16
synaptotagmin XVI
chr2_-_50428395 1.388 NM_138735
NRXN1
neurexin 1
chrX_-_24575146 1.387 PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr15_+_58083737 1.356


chr6_-_49712483 1.355 NM_000324
RHAG
Rh-associated glycoprotein
chr17_+_14145051 1.351 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr12_-_16650697 1.349 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_-_194844061 1.347 NM_198503
KCNT2
potassium channel, subfamily T, member 2
chr12_-_14024187 1.328 NM_000834
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr4_-_174774368 1.326 NM_006792
MORF4
mortality factor 4
chr11_-_31789431 1.315 NM_000280
NM_001604
PAX6

paired box 6

chr7_+_27248688 1.309 NM_001989
EVX1
even-skipped homeobox 1
chr3_-_79899748 1.288 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr15_+_58083712 1.281 NM_012182
FOXB1
forkhead box B1
chr12_+_109956210 1.271 NM_015267
CUX2
cut-like homeobox 2
chr3_+_46370228 1.264 NM_001123041
NM_001123396
CCR2

chemokine (C-C motif) receptor 2

chr5_-_146237826 1.261 PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr2_-_200038055 1.255 NM_001172517
SATB2
SATB homeobox 2
chr11_+_62813947 1.251 NM_001039752
SLC22A10
solute carrier family 22, member 10
chr10_+_83625049 1.245 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr1_-_226712140 1.238 NM_033445
HIST3H2A
histone cluster 3, H2a
chr8_-_23768242 1.234 NM_003155
STC1
stanniocalcin 1
chr3_-_62334229 1.227 NM_018008
FEZF2
FEZ family zinc finger 2
chr19_-_48815572 1.217 ZNF428
zinc finger protein 428
chr15_-_56145140 1.217 NM_003888
NM_170696
ALDH1A2

aldehyde dehydrogenase 1 family, member A2

chr1_+_226712430 1.215 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr4_+_174688183 1.212 NBLA00301
Nbla00301
chr20_+_34019942 1.198 NM_080834
C20orf152
chromosome 20 open reading frame 152
chr11_-_114880275 1.177 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr18_-_28606839 1.174 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr11_-_26700121 1.169 NM_178498
SLC5A12
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr5_-_134899537 1.166 NM_006161
NEUROG1
neurogenin 1
chr10_-_64248932 1.164 NM_001136178
EGR2
early growth response 2
chr4_+_134289893 1.152 NM_020815
NM_032961
PCDH10

protocadherin 10

chr9_+_134843918 1.145 NM_001135031
NM_004188
GFI1B

growth factor independent 1B transcription repressor

chr6_+_101953581 1.145 NM_001166247
NM_021956
NM_175768
GRIK2


glutamate receptor, ionotropic, kainate 2


chr18_+_57308754 1.139 NM_031891
CDH20
cadherin 20, type 2
chr15_-_43193614 1.124 DUOX2
dual oxidase 2
chr4_-_163304567 1.104 NM_001128427
NM_001128428
NM_020116
FSTL5


follistatin-like 5


chr6_+_55147029 1.096 NM_001526
HCRTR2
hypocretin (orexin) receptor 2
chr3_-_173648896 1.096 NM_004122
NM_198407
GHSR

growth hormone secretagogue receptor

chr13_-_27441423 1.087 CDX2
caudal type homeobox 2
chr4_-_174686918 1.086 HAND2
heart and neural crest derivatives expressed 2
chr3_-_133236447 1.085 NM_130808
CPNE4
copine IV
chr15_-_43193637 1.083 NM_014080
DUOX2
dual oxidase 2
chr2_-_200033445 1.077 SATB2
SATB homeobox 2
chr7_+_113513828 1.075 FOXP2
forkhead box P2
chr5_-_146238336 1.069 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr4_+_93444572 1.068 NM_001510
GRID2
glutamate receptor, ionotropic, delta 2
chr4_-_41579325 1.062


chr2_+_102456193 1.062 NM_001011552
SLC9A4
solute carrier family 9 (sodium/hydrogen exchanger), member 4
chr13_-_27441290 1.061 NM_001265
CDX2
caudal type homeobox 2
chrX_-_24575375 1.051 NM_001163265
NM_004845
PCYT1B

phosphate cytidylyltransferase 1, choline, beta

chr11_-_31789168 1.040 PAX6
paired box 6
chr8_+_19841209 1.019 LPL
lipoprotein lipase
chr5_-_88004891 1.017 LOC645323
hypothetical LOC645323
chr4_+_81325447 1.002 NM_020226
PRDM8
PR domain containing 8
chr1_+_66230977 0.987 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr10_-_97190885 0.986 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr18_+_61568467 0.984 NM_033646
CDH7
cadherin 7, type 2
chr15_+_58083798 0.971 FOXB1
forkhead box B1
chr3_-_24511180 0.971 NM_001128176
NM_000461
NM_001128177
THRB


thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)


chr5_+_149526533 0.957 NM_001804
CDX1
caudal type homeobox 1
chr11_+_119616112 0.950 NM_014352
POU2F3
POU class 2 homeobox 3
chr2_-_210726539 0.942 C2orf67
chromosome 2 open reading frame 67
chr20_+_17155669 0.942 PCSK2
proprotein convertase subtilisin/kexin type 2
chr12_+_54231249 0.941 NM_001005494
OR6C4
olfactory receptor, family 6, subfamily C, member 4
chr3_+_182912769 0.938 SOX2
SRY (sex determining region Y)-box 2
chr6_+_32003380 0.933 C2
complement component 2
chr8_+_19841120 0.932 LPL
lipoprotein lipase
chrX_+_99726445 0.929 NM_022144
TNMD
tenomodulin
chr1_+_168381811 0.922 NM_001136107
METTL11B
methyltransferase like 11B
chr20_+_17155680 0.918 PCSK2
proprotein convertase subtilisin/kexin type 2
chr7_+_113513726 0.913 FOXP2
forkhead box P2
chr12_-_80676562 0.905 PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr13_-_27441143 0.904 CDX2
caudal type homeobox 2
chr12_-_10846435 0.903 NM_023919
TAS2R7
taste receptor, type 2, member 7
chr1_-_175400665 0.897 ASTN1
astrotactin 1
chr8_+_19841010 0.892 LPL
lipoprotein lipase
chr22_+_29848923 0.891 NM_001002837
INPP5J
inositol polyphosphate-5-phosphatase J
chr1_-_175400441 0.891 ASTN1
astrotactin 1
chr13_+_57103789 0.883 NM_001040429
PCDH17
protocadherin 17
chr3_-_193928038 0.877 NM_004113
FGF12
fibroblast growth factor 12
chrX_-_109570113 0.874 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr10_+_50488352 0.865 NM_003055
SLC18A3
solute carrier family 18 (vesicular acetylcholine), member 3
chr4_+_2013517 0.861 NM_001168243
NM_001141936
C4orf48

chromosome 4 open reading frame 48

chr12_-_94469357 0.860 NM_032147
USP44
ubiquitin specific peptidase 44
chr12_+_52713098 0.857 NM_018953
HOXC5
homeobox C5
chr3_-_195601283 0.854 NM_004488
GP5
glycoprotein V (platelet)
chr4_-_154929657 0.853 NM_003013
SFRP2
secreted frizzled-related protein 2
chr5_-_147142249 0.852 JAKMIP2
janus kinase and microtubule interacting protein 2
chr18_-_29412148 0.851


chr18_+_59374372 0.848 NM_080474
SERPINB12
serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr3_+_182912405 0.848 NM_003106
SOX2
SRY (sex determining region Y)-box 2
chr7_+_94377145 0.846 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory (inhibitor) subunit 9A


chr8_-_21701616 0.838 GFRA2
GDNF family receptor alpha 2
chr3_-_152173475 0.835 NM_001195794
NM_174878
CLRN1

clarin 1

chr12_-_16650687 0.824 LMO3
LIM domain only 3 (rhombotin-like 2)
chr5_-_111340421 0.824 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chrX_+_9391314 0.822 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr6_-_128281434 0.821 NM_001164687
THEMIS
thymocyte selection associated
chr8_-_93181091 0.814 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_192767494 0.811 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr7_-_50103335 0.806 NM_001159878
NM_007009
ZPBP

zona pellucida binding protein

chr18_+_29412538 0.798 NM_030632
ASXL3
additional sex combs like 3 (Drosophila)
chr6_+_108593907 0.798 NM_003269
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr20_+_17155617 0.797 NM_002594
PCSK2
proprotein convertase subtilisin/kexin type 2
chr1_-_151296611 0.786 NM_005988
SPRR2A
small proline-rich protein 2A
chr3_-_166397142 0.782 NM_014926
SLITRK3
SLIT and NTRK-like family, member 3
chr1_-_194844299 0.776 KCNT2
potassium channel, subfamily T, member 2
chr7_+_45899621 0.776


chr16_+_23754772 0.775 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr20_+_9442995 0.774 C20orf103
chromosome 20 open reading frame 103
chr8_+_19840861 0.771 NM_000237
LPL
lipoprotein lipase
chr2_-_238813284 0.765 HES6
hairy and enhancer of split 6 (Drosophila)
chr12_+_56290229 0.760 NM_001111270
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr12_-_16652202 0.752 NM_001001395
LMO3
LIM domain only 3 (rhombotin-like 2)
chr10_+_95838801 0.752 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr13_-_60887655 0.751 NM_022843
PCDH20
protocadherin 20
chr12_-_10853940 0.751 NM_023917
TAS2R9
taste receptor, type 2, member 9
chr3_-_140879463 0.750 NM_178177
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr16_+_23754822 0.748 PRKCB
protein kinase C, beta
chr14_-_33489708 0.747 NM_022073
EGLN3
egl nine homolog 3 (C. elegans)
chr14_-_105623358 0.740 IGHA1
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr3_+_135996990 0.734 EPHB1
EPH receptor B1
chr3_+_143824955 0.729 NM_002670
PLS1
plastin 1
chr15_-_40537002 0.725 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr1_-_102234959 0.719 OLFM3
olfactomedin 3
chr5_+_140767953 0.719 NM_018926
NM_032100
PCDHGB6

protocadherin gamma subfamily B, 6

chr10_-_64246080 0.718 EGR2
early growth response 2
chr14_+_64077171 0.718 HSPA2
heat shock 70kDa protein 2
chr5_-_177950161 0.715 NM_173465
COL23A1
collagen, type XXIII, alpha 1
chr6_+_132901119 0.713 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chr4_+_41309690 0.712 LIMCH1
LIM and calponin homology domains 1
chr17_-_72045218 0.709 NM_134268
CYGB
cytoglobin
chr20_-_49852353 0.707 NM_020436
SALL4
sal-like 4 (Drosophila)
chr2_-_104834344 0.699 LOC100506421
hypothetical LOC100506421
chr4_-_100575313 0.696 NM_001166504
NM_000673
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr8_-_72431274 0.695 NM_172058
NM_172059
NM_172060
EYA1


eyes absent homolog 1 (Drosophila)


chr19_+_40511909 0.694 NM_001185099
NM_001185100
NM_001185101
NM_001771
CD22



CD22 molecule



chr18_+_61569136 0.693 NM_004361
CDH7
cadherin 7, type 2
chr10_-_64246129 0.686 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr2_+_165860528 0.685 NM_001040143
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr7_-_141320041 0.684 NM_176817
TAS2R38
taste receptor, type 2, member 38
chr11_-_84312085 0.684 NM_001364
DLG2
discs, large homolog 2 (Drosophila)
chr22_-_43784444 0.684 NM_001135862
PHF21B
PHD finger protein 21B
chr7_-_76667045 0.681 NM_006682
FGL2
fibrinogen-like 2
chr4_+_41309482 0.677 LIMCH1
LIM and calponin homology domains 1
chr8_+_104900591 0.675 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr18_+_61568825 0.671 CDH7
cadherin 7, type 2
chr8_-_95289945 0.670 NM_004063
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr1_+_65503011 0.661 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr1_-_151280201 0.661 NM_006945
SPRR2D
small proline-rich protein 2D
chr7_-_31347032 0.660 NM_022728
NEUROD6
neurogenic differentiation 6
chr12_-_61832856 0.658 NM_000706
AVPR1A
arginine vasopressin receptor 1A
chr14_-_56346849 0.652 NM_021728
OTX2
orthodenticle homeobox 2
chr5_-_36337756 0.651 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr7_-_36991189 0.649 NM_001039459
ELMO1
engulfment and cell motility 1
chr3_+_1109619 0.647 NM_014461
CNTN6
contactin 6
chr17_-_75427644 0.646 NM_003655
CBX4
chromobox homolog 4
chr2_-_238813365 0.644 NM_001142853
NM_018645
HES6

hairy and enhancer of split 6 (Drosophila)

chr11_-_57171554 0.641 YPEL4
yippee-like 4 (Drosophila)
chr2_-_51112743 0.641 NRXN1
neurexin 1
chr4_-_41445693 0.637 NM_003924
PHOX2B
paired-like homeobox 2b
chr7_-_92693716 0.636 NM_001039372
HEPACAM2
HEPACAM family member 2
chr4_-_47534815 0.636 NM_006587
CORIN
corin, serine peptidase

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.37 8.53e-19 GO:0032501 multicellular organismal process
1.71 6.20e-13 GO:0007399 nervous system development
1.45 1.95e-11 GO:0048731 system development
1.40 2.67e-11 GO:0007275 multicellular organismal development
1.41 8.08e-11 GO:0048856 anatomical structure development
1.36 1.51e-10 GO:0032502 developmental process
1.78 9.97e-09 GO:0022008 neurogenesis
1.90 1.51e-08 GO:0030182 neuron differentiation
1.23 2.54e-08 GO:0050896 response to stimulus
1.78 3.96e-08 GO:0048699 generation of neurons
1.46 2.16e-07 GO:0030154 cell differentiation
1.50 3.56e-07 GO:0003008 system process
1.67 9.18e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.17 9.61e-07 GO:0065007 biological regulation
1.19 1.36e-06 GO:0050794 regulation of cellular process
1.18 1.88e-06 GO:0050789 regulation of biological process
1.42 2.35e-06 GO:0048869 cellular developmental process
1.94 2.80e-06 GO:0007417 central nervous system development
1.40 8.07e-06 GO:0006355 regulation of transcription, DNA-dependent
1.65 9.24e-06 GO:0048468 cell development
1.38 1.02e-05 GO:0051252 regulation of RNA metabolic process
1.37 1.21e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.42 1.81e-05 GO:0048513 organ development
1.50 2.17e-05 GO:0050877 neurological system process
1.35 2.72e-05 GO:0010468 regulation of gene expression
1.35 3.33e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.81 4.57e-05 GO:0048666 neuron development
1.29 5.53e-05 GO:0060255 regulation of macromolecule metabolic process
1.32 1.36e-04 GO:0031326 regulation of cellular biosynthetic process
1.31 1.95e-04 GO:0009889 regulation of biosynthetic process
1.26 2.49e-04 GO:0080090 regulation of primary metabolic process
1.81 6.14e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.65 1.04e-03 GO:0010628 positive regulation of gene expression
1.68 1.11e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.25 1.17e-03 GO:0031323 regulation of cellular metabolic process
1.55 1.94e-03 GO:0006351 transcription, DNA-dependent
1.29 2.03e-03 GO:0048518 positive regulation of biological process
1.59 2.23e-03 GO:0007155 cell adhesion
1.59 2.23e-03 GO:0022610 biological adhesion
1.59 3.04e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.49 4.86e-03 GO:0007154 cell communication
3.74 5.06e-03 GO:0048663 neuron fate commitment
1.30 6.24e-03 GO:0042221 response to chemical stimulus
1.21 6.56e-03 GO:0019222 regulation of metabolic process
1.22 8.71e-03 GO:0023052 signaling
1.92 9.10e-03 GO:0016337 cell-cell adhesion
1.77 9.63e-03 GO:0007409 axonogenesis
1.70 1.02e-02 GO:0031175 neuron projection development
1.82 1.21e-02 GO:0007420 brain development
1.54 1.46e-02 GO:0007267 cell-cell signaling
1.73 1.68e-02 GO:0032583 regulation of gene-specific transcription
1.73 1.68e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.26 1.90e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.67 1.97e-02 GO:0001775 cell activation
1.57 2.33e-02 GO:0051254 positive regulation of RNA metabolic process
2.81 2.66e-02 GO:0021953 central nervous system neuron differentiation
1.46 2.74e-02 GO:0032774 RNA biosynthetic process
1.50 2.78e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.36 2.78e-02 GO:0009653 anatomical structure morphogenesis
1.25 3.35e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.66 3.39e-02 GO:0019226 transmission of nerve impulse
1.66 3.39e-02 GO:0035637 multicellular organismal signaling
2.25 3.71e-02 GO:0045165 cell fate commitment
1.40 4.36e-02 GO:0010604 positive regulation of macromolecule metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.32 8.01e-11 GO:0005886 plasma membrane
1.31 1.87e-10 GO:0071944 cell periphery
1.38 2.83e-06 GO:0044459 plasma membrane part
1.72 4.87e-03 GO:0043005 neuron projection
1.50 4.24e-02 GO:0030054 cell junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.85 5.42e-13 GO:0001071 nucleic acid binding transcription factor activity
1.85 5.42e-13 GO:0003700 sequence-specific DNA binding transcription factor activity
2.00 8.11e-12 GO:0043565 sequence-specific DNA binding
1.64 2.01e-07 GO:0030528 transcription regulator activity
1.34 1.48e-04 GO:0004871 signal transducer activity
1.34 1.48e-04 GO:0060089 molecular transducer activity
1.51 1.78e-04 GO:0005102 receptor binding
1.31 2.20e-04 GO:0003677 DNA binding
1.37 4.41e-04 GO:0004872 receptor activity
3.43 1.13e-03 GO:0004879 ligand-dependent nuclear receptor activity
3.43 2.19e-03 GO:0003707 steroid hormone receptor activity
1.38 6.88e-03 GO:0004888 transmembrane receptor activity