Motif ID: PRDM1.p3

Z-value: 1.202


Transcription factors associated with PRDM1.p3:

Gene SymbolEntrez IDGene Name
PRDM1 639 PR domain containing 1, with ZNF domain

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PRDM1chr6_+_1066408810.486.1e-02Click!


Activity profile for motif PRDM1.p3.

activity profile for motif PRDM1.p3


Sorted Z-values histogram for motif PRDM1.p3

Sorted Z-values for motif PRDM1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM1.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_142795269 3.798 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr16_+_55580910 2.834 NM_032206
NLRC5
NLR family, CARD domain containing 5
chr21_+_42807052 2.581 SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr5_+_73145098 2.331 RGNEF
190 kDa guanine nucleotide exchange factor
chr6_+_167445284 2.270 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr6_+_37081387 2.148 NM_173558
FGD2
FYVE, RhoGEF and PH domain containing 2
chr4_+_187227302 1.858 NM_003265
TLR3
toll-like receptor 3
chr20_-_5048443 1.733 NM_182649
PCNA
proliferating cell nuclear antigen
chr11_+_28088406 1.496 METTL15
methyltransferase like 15
chr12_+_25096472 1.456 NM_006152
LRMP
lymphoid-restricted membrane protein
chr17_+_53602013 1.422 NM_001004707
OR4D2
olfactory receptor, family 4, subfamily D, member 2
chr17_-_45626364 1.308


chr2_-_230792844 1.303 NM_004509
NM_004510
NM_080424
SP110


SP110 nuclear body protein


chr10_+_63478974 1.249 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr11_-_85015961 1.175 NM_001142699
DLG2
discs, large homolog 2 (Drosophila)
chr14_+_23771464 1.163 NM_001002000
NM_001002001
GMPR2

guanosine monophosphate reductase 2

chr1_+_220884257 1.154 MIA3
melanoma inhibitory activity family, member 3
chr3_+_186529376 1.108 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr14_-_23771312 1.097 NEDD8
neural precursor cell expressed, developmentally down-regulated 8
chr10_-_35143900 1.088 NM_001184785
NM_001184786
NM_001184787
NM_001184788
NM_001184789
NM_001184790
NM_001184791
NM_001184792
NM_001184793
NM_001184794
NM_019619
PARD3










par-3 partitioning defective 3 homolog (C. elegans)











Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 53 entries
enrichment   p-value GO term description
10.86 2.31e-05 GO:0060337 type I interferon-mediated signaling pathway
10.86 2.31e-05 GO:0071357 cellular response to type I interferon
10.69 2.71e-05 GO:0034340 response to type I interferon
10.16 1.02e-03 GO:0006521 regulation of cellular amino acid metabolic process
8.83 3.06e-03 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
8.83 3.06e-03 GO:0072395 signal transduction involved in cell cycle checkpoint
8.83 3.06e-03 GO:0072401 signal transduction involved in DNA integrity checkpoint
8.83 3.06e-03 GO:0072404 signal transduction involved in G1/S transition checkpoint
8.83 3.06e-03 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
8.83 3.06e-03 GO:0072422 signal transduction involved in DNA damage checkpoint
8.83 3.06e-03 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
8.83 3.06e-03 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
8.53 9.84e-04 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
8.42 4.43e-03 GO:0033238 regulation of cellular amine metabolic process
8.42 4.43e-03 GO:0071158 positive regulation of cell cycle arrest
8.04 6.28e-03 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
7.92 7.02e-03 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
7.87 1.97e-03 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
7.77 2.20e-03 GO:0031575 mitotic cell cycle G1/S transition checkpoint
7.77 2.20e-03 GO:0051443 positive regulation of ubiquitin-protein ligase activity

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
67.30 3.58e-02 GO:0071797 LUBAC complex
20.19 5.35e-05 GO:0005839 proteasome core complex
8.55 6.58e-04 GO:0000502 proteasome complex

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
19.23 1.01e-04 GO:0004298 threonine-type endopeptidase activity
19.23 1.01e-04 GO:0070003 threonine-type peptidase activity
2.09 3.14e-02 GO:0001071 nucleic acid binding transcription factor activity
2.09 3.14e-02 GO:0003700 sequence-specific DNA binding transcription factor activity