Motif ID: PRRX1,2.p2

Z-value: 2.761


Transcription factors associated with PRRX1,2.p2:

Gene SymbolEntrez IDGene Name
PRRX1 5396 paired related homeobox 1
PRRX2 51450 paired related homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PRRX1chr1_+_1688988980.401.2e-01Click!
PRRX2chr9_+_131467837-0.078.0e-01Click!


Activity profile for motif PRRX1,2.p2.

activity profile for motif PRRX1,2.p2


Sorted Z-values histogram for motif PRRX1,2.p2

Sorted Z-values for motif PRRX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PRRX1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_35658852 4.982 NM_016300
 ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr3_+_35697432 4.498 NM_198399
 ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr12_-_23993830 4.345 NM_006940
 SOX5
SRY (sex determining region Y)-box 5
chr10_-_69125932 3.773 NM_013266
 CTNNA3
catenin (cadherin-associated protein), alpha 3
chr4_+_74520796 3.373 NM_001134
 AFP
alpha-fetoprotein
chr1_+_198263352 3.329 NM_003822
NM_205860
 NR5A2

nuclear receptor subfamily 5, group A, member 2

chr7_-_83116414 3.251 NM_012431
 SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr6_+_83129641 3.097 NM_006670
 TPBG
trophoblast glycoprotein
chr6_-_130578110 3.070 NM_152552
 SAMD3
sterile alpha motif domain containing 3
chr6_+_105511615 3.017 NM_001004317
 LIN28B
lin-28 homolog B (C. elegans)
chr13_+_22653059 2.957 NM_000231
 SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr6_+_132915522 2.937 NM_053278
 TAAR8
trace amine associated receptor 8
chr2_-_180135559 2.848 NM_001113398
 ZNF385B
zinc finger protein 385B
chr2_+_234490781 2.776 NM_024080
 TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr2_-_206790871 2.752 NM_001098199
NM_005279
 GPR1

G protein-coupled receptor 1

chr12_+_52708460 2.677 NM_004503
 HOXC6
homeobox C6
chr17_-_36113502 2.659 NM_019016
 KRT24
keratin 24
chr3_-_152541129 2.632 NM_176876
 P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr11_+_113280727 2.585 NM_006028
 HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr6_+_50894397 2.556 NM_003221
 TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.57 1.82e-05 GO:0007606 sensory perception of chemical stimulus
1.56 2.47e-04 GO:0007608 sensory perception of smell
1.40 1.20e-04 GO:0007600 sensory perception
1.33 4.87e-02 GO:2000026 regulation of multicellular organismal development
1.24 1.97e-03 GO:0003008 system process
1.24 3.43e-02 GO:0050877 neurological system process
1.17 7.54e-09 GO:0032501 multicellular organismal process
1.14 1.81e-07 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.34 1.21e-03 GO:0005615 extracellular space
1.33 9.16e-05 GO:0044421 extracellular region part
1.29 1.79e-08 GO:0005576 extracellular region
1.15 1.69e-05 GO:0071944 cell periphery
1.15 4.38e-05 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.59 2.14e-05 GO:0004984 olfactory receptor activity
1.59 4.30e-02 GO:0005125 cytokine activity
1.39 2.77e-05 GO:0004930 G-protein coupled receptor activity
1.37 7.88e-08 GO:0004888 transmembrane receptor activity
1.31 1.13e-07 GO:0004872 receptor activity
1.30 1.31e-03 GO:0005102 receptor binding
1.27 4.07e-07 GO:0004871 signal transducer activity
1.27 4.07e-07 GO:0060089 molecular transducer activity