Motif ID: RBPJ.p2

Z-value: 0.615


Transcription factors associated with RBPJ.p2:

Gene SymbolEntrez IDGene Name
RBPJ 3516 recombination signal binding protein for immunoglobulin kappa J region

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RBPJchr4_+_259312820.273.1e-01Click!


Activity profile for motif RBPJ.p2.

activity profile for motif RBPJ.p2


Sorted Z-values histogram for motif RBPJ.p2

Sorted Z-values for motif RBPJ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RBPJ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_-_3097070 1.045 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr2_+_220200530 0.609 NM_005070
NM_201574
SLC4A3

solute carrier family 4, anion exchanger, member 3

chr6_+_73388291 0.574 NM_001160130
NM_001160132
NM_001160133
NM_001160134
NM_019842
KCNQ5




potassium voltage-gated channel, KQT-like subfamily, member 5




chr17_+_7883076 0.555 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr9_-_84867862 0.405 NM_152573
RASEF
RAS and EF-hand domain containing
chr17_+_7846636 0.404 NM_000180
GUCY2D
guanylate cyclase 2D, membrane (retina-specific)
chr10_+_124310170 0.387 NM_004406
NM_007329
NM_017579
DMBT1


deleted in malignant brain tumors 1


chr16_-_52877868 0.384 NM_024336
IRX3
iroquois homeobox 3
chr11_-_31796061 0.381 NM_001127612
PAX6
paired box 6
chr14_-_60185659 0.369 NM_005982
SIX1
SIX homeobox 1
chrX_-_21586337 0.362 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr19_+_49268106 0.360 NM_001037813
ZNF284
zinc finger protein 284
chr5_+_140690387 0.348 NM_018912
NM_031993
PCDHGA1

protocadherin gamma subfamily A, 1

chr16_-_52877829 0.346 IRX3
iroquois homeobox 3
chr8_+_82807218 0.333 NM_152284
CHMP4C
chromatin modifying protein 4C
chr16_-_52877467 0.330 IRX3
iroquois homeobox 3
chr10_-_38186227 0.327 NM_021045
ZNF248
zinc finger protein 248
chr6_+_129245978 0.326 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chr16_+_67698943 0.322 NM_005329
HAS3
hyaluronan synthase 3
chr11_-_125278296 0.318 NM_031307
PUS3
pseudouridylate synthase 3
chr17_-_31281843 0.317 NM_001034836
NM_001163120
NM_001163121
NM_145654
RDM1



RAD52 motif 1



chr22_-_45311730 0.312 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr9_-_84867604 0.307 RASEF
RAS and EF-hand domain containing
chr5_+_140762551 0.290 NM_018921
NM_032089
PCDHGA9

protocadherin gamma subfamily A, 9

chr6_+_42639929 0.290 UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr14_-_91372365 0.289 NM_001128595
NM_152332
TC2N

tandem C2 domains, nuclear

chr2_+_14690290 0.289 FAM84A
family with sequence similarity 84, member A
chr11_+_66952462 0.287 NM_003952
RPS6KB2
ribosomal protein S6 kinase, 70kDa, polypeptide 2
chr6_+_28335070 0.286 NM_001007531
NKAPL
NFKB activating protein-like
chr19_-_51058177 0.284 NM_004819
SYMPK
symplekin
chr4_-_139382672 0.284 NM_014331
SLC7A11
solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
chr12_-_56445653 0.272 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr7_-_19715127 0.268 NM_001002926
TWISTNB
TWIST neighbor
chr19_-_41849558 0.266 NM_153257
ZNF461
zinc finger protein 461
chr20_-_697127 0.265 NM_033409
C20orf54
chromosome 20 open reading frame 54
chr9_-_34512972 0.257 NM_198573
ENHO
energy homeostasis associated
chr19_+_60580015 0.255 NM_139172
TMEM190
transmembrane protein 190
chr2_-_220144427 0.254 OBSL1
obscurin-like 1
chr19_+_5632016 0.254 NM_198704
NM_198705
NM_198533
NM_198707
NM_198706
NM_198708
HSD11B1L





hydroxysteroid (11-beta) dehydrogenase 1-like





chr19_-_15204767 0.253 NM_001142886
EPHX3
epoxide hydrolase 3
chr13_+_31318828 0.249 EEF1DP3
eukaryotic translation elongation factor 1 delta pseudogene 3
chr22_+_33983444 0.238 NM_001003681
HMGXB4
HMG box domain containing 4
chr19_-_10486679 0.237 S1PR5
sphingosine-1-phosphate receptor 5
chr5_+_85949511 0.234 COX7C
cytochrome c oxidase subunit VIIc
chr16_+_8622974 0.232 NM_024109
METTL22
methyltransferase like 22
chr19_-_49500966 0.232 NM_004234
ZNF235
zinc finger protein 235
chr20_-_29360048 0.230 NM_001037731
DEFB116
defensin, beta 116
chr9_+_71625550 0.224 NM_001010940
C9orf135
chromosome 9 open reading frame 135
chr10_+_111755715 0.222 NM_019903
ADD3
adducin 3 (gamma)
chr2_+_14690260 0.222 NM_145175
FAM84A
family with sequence similarity 84, member A
chr1_-_26571812 0.222 NM_001114759
NM_173574
ZNF683

zinc finger protein 683

chr8_+_12847521 0.221 NM_020844
KIAA1456
KIAA1456
chr22_+_28493351 0.221 NM_001003684
NM_013387
UQCR10

ubiquinol-cytochrome c reductase, complex III subunit X

chr6_+_126112588 0.220 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr1_-_925215 0.218 HES4
hairy and enhancer of split 4 (Drosophila)
chr11_-_2118916 0.216 NM_001127598
IGF2
insulin-like growth factor 2 (somatomedin A)
chr5_+_140772691 0.215 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr12_-_83954185 0.209 NM_001100917
TSPAN19
tetraspanin 19
chr18_-_26876622 0.208 NM_001941
NM_024423
DSC3

desmocollin 3

chr6_+_57290357 0.207 NM_000947
PRIM2
primase, DNA, polypeptide 2 (58kDa)
chr5_+_147238466 0.205 NM_054023
SCGB3A2
secretoglobin, family 3A, member 2
chr11_-_75057062 0.203 NM_033063
NM_207577
MAP6

microtubule-associated protein 6

chr20_-_23350038 0.201 NM_022080
NAPB
N-ethylmaleimide-sensitive factor attachment protein, beta
chr21_-_31853160 0.201 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr2_-_152664056 0.200 CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr10_-_126128539 0.199 NM_001146340
NKX1-2
NK1 homeobox 2
chr5_+_150137700 0.198 NM_032947
C5orf62
chromosome 5 open reading frame 62
chr5_+_85949518 0.198 NM_001867
COX7C
cytochrome c oxidase subunit VIIc
chr19_-_53914768 0.195 NM_001130915
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr10_+_103882776 0.192 NM_015062
PPRC1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr20_-_42249146 0.191 JPH2
junctophilin 2
chr19_-_10489606 0.191 NM_001166215
S1PR5
sphingosine-1-phosphate receptor 5
chr2_-_50428395 0.191 NM_138735
NRXN1
neurexin 1
chr8_+_75899326 0.190 NM_015886
PI15
peptidase inhibitor 15
chr10_-_32707549 0.187 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr11_-_2118743 0.185 IGF2
insulin-like growth factor 2 (somatomedin A)
chr12_+_115481568 0.183 NM_001085481
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chrX_-_118809584 0.180 NM_001000
RPL39
ribosomal protein L39
chr19_-_59368625 0.179 NM_001145303
NM_144686
TMC4

transmembrane channel-like 4

chr1_+_36462625 0.179 THRAP3
thyroid hormone receptor associated protein 3
chr10_-_43464157 0.178 NM_001005368
ZNF32
zinc finger protein 32
chr14_-_53491019 0.178 NM_130851
BMP4
bone morphogenetic protein 4
chr17_+_71232370 0.178 NM_001005619
ITGB4
integrin, beta 4
chr5_+_112340326 0.176 NM_152624
DCP2
DCP2 decapping enzyme homolog (S. cerevisiae)
chr17_-_16059514 0.172 NM_006311
NCOR1
nuclear receptor corepressor 1
chr16_+_23673448 0.172 NM_022097
CHP2
calcineurin B homologous protein 2
chr19_-_56549853 0.171 NM_001014763
ETFB
electron-transfer-flavoprotein, beta polypeptide
chr11_-_75056761 0.170 MAP6
microtubule-associated protein 6
chr10_-_51041156 0.170 NM_003631
AGAP8
LOC728407
PARG
ArfGAP with GTPase domain, ankyrin repeat and PH domain 8
poly(ADP-ribose) glycohydrolase pseudogene
poly (ADP-ribose) glycohydrolase
chr6_+_32003180 0.169 NM_000063
NM_001145903
C2

complement component 2

chr2_+_87536174 0.168 NCRNA00152
non-protein coding RNA 152
chr14_-_59407103 0.168 NM_021136
RTN1
reticulon 1
chr19_-_60382529 0.167 SYT5
synaptotagmin V
chrX_+_136475979 0.166 NM_003413
ZIC3
Zic family member 3 (odd-paired homolog, Drosophila)
chr5_+_42792676 0.166 NM_001134848
CCDC152
coiled-coil domain containing 152
chr16_+_24985721 0.166 LOC283887
hypothetical protein LOC283887
chr17_+_7549138 0.164 NM_001406
EFNB3
ephrin-B3
chr3_+_114414064 0.163 NM_033254
BOC
Boc homolog (mouse)
chr2_+_187059115 0.163 NM_018471
ZC3H15
zinc finger CCCH-type containing 15
chr3_+_131547048 0.163 NM_153264
COL6A5
collagen, type VI, alpha 5
chr7_-_75876830 0.162 NM_080744
SRCRB4D
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr2_+_227900471 0.162 NM_020194
MFF
mitochondrial fission factor
chr17_-_31281398 0.161 NM_001163122
NM_001163124
NM_001163125
NM_001163130
RDM1



RAD52 motif 1



chr11_-_75057299 0.160 MAP6
microtubule-associated protein 6
chr17_+_18700385 0.156 PRPSAP2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr4_-_140443061 0.155 NM_001184987
NM_001184988
NM_001184989
NM_001184990
NDUFC1



NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa



chr1_-_145699308 0.151 NM_181703
GJA5
gap junction protein, alpha 5, 40kDa
chr12_+_83954229 0.149 NM_001079910
NM_032165
LRRIQ1

leucine-rich repeats and IQ motif containing 1

chr16_+_21872201 0.149 UQCRC2
ubiquinol-cytochrome c reductase core protein II
chr9_+_99214000 0.146 NM_014290
TDRD7
tudor domain containing 7
chr8_-_102031943 0.146 NM_001135702
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr8_+_102574012 0.146 GRHL2
grainyhead-like 2 (Drosophila)
chr17_+_40594046 0.146 NM_144608
HEXIM2
hexamthylene bis-acetamide inducible 2
chr3_-_49942198 0.144 NM_001142501
NM_032355
MON1A

MON1 homolog A (yeast)

chr8_+_102573837 0.143 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr2_+_187059277 0.142 ZC3H15
zinc finger CCCH-type containing 15
chr9_+_99214190 0.142 TDRD7
tudor domain containing 7
chr6_-_169395847 0.141 THBS2
thrombospondin 2
chr10_+_70517863 0.141 SRGN
serglycin
chr6_+_30702586 0.139 NM_024909
NM_001031722
NM_001190724
ATAT1


alpha tubulin acetyltransferase 1


chr17_+_44927591 0.137 NM_002507
NGFR
nerve growth factor receptor
chr1_-_210275402 0.136 NM_015434
INTS7
integrator complex subunit 7
chr6_+_126112506 0.133 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr1_+_203740306 0.133 NM_002596
NM_212502
NM_212503
CDK18


cyclin-dependent kinase 18


chr3_-_114047479 0.133 NM_001008784
CD200R1L
CD200 receptor 1-like
chr19_-_8548232 0.133 MYO1F
myosin IF
chrX_-_70248022 0.133 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr10_-_92670764 0.133 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr2_+_69093641 0.132 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr2_+_87536106 0.131 NCRNA00152
non-protein coding RNA 152
chr5_-_137542198 0.131 NM_001164326
NM_006696
NM_139199
BRD8


bromodomain containing 8


chr1_-_85131439 0.130 NM_012152
LPAR3
lysophosphatidic acid receptor 3
chr1_-_925332 0.130 NM_001142467
NM_021170
HES4

hairy and enhancer of split 4 (Drosophila)

chr16_-_4757125 0.130 NM_021646
ZNF500
zinc finger protein 500
chr16_+_67328737 0.129 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr14_-_20562962 0.129 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr6_+_30959839 0.129 NM_001954
DDR1
discoidin domain receptor tyrosine kinase 1
chr4_+_75242671 0.127 NM_001144978
MTHFD2L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr8_-_120914233 0.126 NM_003184
TAF2
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
chr14_+_76717835 0.125 NM_020431
TMEM63C
transmembrane protein 63C
chr20_-_44575599 0.125 NM_018102
NM_199441
ZNF334

zinc finger protein 334

chr5_+_178383381 0.123 NM_001136116
ZNF879
zinc finger protein 879
chr5_+_137542652 0.122 KIF20A
kinesin family member 20A
chr1_+_40769819 0.122 NM_152373
ZNF684
zinc finger protein 684
chr3_+_143925904 0.121 NM_003304
TRPC1
transient receptor potential cation channel, subfamily C, member 1
chr1_-_195302973 0.120 NM_001994
F13B
coagulation factor XIII, B polypeptide
chr15_-_62460622 0.119 NM_001029989
NM_014736
KIAA0101

KIAA0101

chr11_+_2880135 0.119 SLC22A18
solute carrier family 22, member 18
chr6_-_49712483 0.119 NM_000324
RHAG
Rh-associated glycoprotein
chr8_-_95720870 0.119 LOC100288748
hypothetical LOC100288748
chr4_-_84475023 0.118 HPSE
heparanase
chr20_+_44070946 0.118 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr20_-_17986520 0.118 NM_021220
OVOL2
ovo-like 2 (Drosophila)
chr1_+_40769877 0.117 ZNF684
zinc finger protein 684
chr2_+_187059237 0.117 ZC3H15
zinc finger CCCH-type containing 15
chr2_-_55698217 0.117 NM_001122964
NM_020463
SMEK2

SMEK homolog 2, suppressor of mek1 (Dictyostelium)

chr14_-_67051773 0.116 NM_182526
TMEM229B
transmembrane protein 229B
chr7_+_138469029 0.116 NM_001144920
NM_001144923
NM_024926
TTC26


tetratricopeptide repeat domain 26


chr4_-_84475036 0.116 NM_001098540
HPSE
heparanase
chr2_-_196641682 0.116 NM_018897
DNAH7
dynein, axonemal, heavy chain 7
chr10_-_51293220 0.116 NM_006327
TIMM23
TIMM23B
translocase of inner mitochondrial membrane 23 homolog (yeast)
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr8_-_12657339 0.115 NM_152271
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr3_+_143925545 0.114


chr11_+_2880104 0.114 SLC22A18
solute carrier family 22, member 18
chr14_+_38806280 0.114 CTAGE5
CTAGE family, member 5
chr1_-_92724181 0.113 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chr19_+_49198916 0.113 NM_006300
ZNF230
zinc finger protein 230
chr16_+_21872178 0.113 UQCRC2
ubiquinol-cytochrome c reductase core protein II
chr19_-_40317829 0.113 NM_139284
LGI4
leucine-rich repeat LGI family, member 4
chr4_-_84475024 0.112 HPSE
heparanase
chr19_-_54775625 0.112 NOSIP
nitric oxide synthase interacting protein
chr11_+_71580816 0.112 NM_016729
FOLR1
folate receptor 1 (adult)
chr1_+_36462583 0.111 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr16_+_56259657 0.111 NM_170776
GPR97
G protein-coupled receptor 97
chr1_-_149247464 0.110 NM_001163258
NM_018379
FAM63A

family with sequence similarity 63, member A

chr5_+_63497408 0.110 NM_001113561
NM_178532
RNF180

ring finger protein 180

chr2_+_233270286 0.110 GIGYF2
GRB10 interacting GYF protein 2
chr10_-_93382779 0.109 PPP1R3C
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr2_-_162883062 0.109 NM_022168
IFIH1
interferon induced with helicase C domain 1
chr12_-_102967828 0.109 GLT8D2
glycosyltransferase 8 domain containing 2
chr2_+_172252473 0.109 DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr14_+_22059212 0.108


chr11_+_5399916 0.108 NM_001004757
OR51Q1
olfactory receptor, family 51, subfamily Q, member 1
chr10_-_28074752 0.107 NM_173576
MKX
mohawk homeobox
chr14_+_74249599 0.105 NM_015962
FCF1
FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)
chr19_-_54775603 0.105 NM_015953
NOSIP
nitric oxide synthase interacting protein
chr2_-_220144511 0.105 NM_001173408
NM_001173431
NM_015311
OBSL1


obscurin-like 1


chr4_-_84474919 0.105 HPSE
heparanase
chr1_+_212227902 0.104 PROX1
prospero homeobox 1
chr16_+_67328715 0.104 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr19_+_42689881 0.104 ZNF793
zinc finger protein 793
chr1_-_1171964 0.104 NM_001014980
FAM132A
family with sequence similarity 132, member A
chr22_-_31183372 0.104 NM_174932
BPIL2
bactericidal/permeability-increasing protein-like 2
chr10_-_27570998 0.102 ACBD5
acyl-CoA binding domain containing 5
chr22_-_28492990 0.102


chr17_-_70367479 0.101 NM_000835
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr19_+_5632139 0.101 HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like
chr9_-_72926333 0.101 NM_001007471
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr8_-_61356436 0.100 NM_004056
CA8
carbonic anhydrase VIII
chr10_-_5436781 0.100 NM_001171864
NM_024803
TUBAL3

tubulin, alpha-like 3


Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 2.88e-03 GO:0044424 intracellular part
1.08 7.92e-03 GO:0005622 intracellular
1.11 8.54e-03 GO:0043231 intracellular membrane-bounded organelle
1.11 1.02e-02 GO:0043227 membrane-bounded organelle
1.54 2.09e-02 GO:0015630 microtubule cytoskeleton
1.15 3.57e-02 GO:0005634 nucleus

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.08 2.57e-03 GO:0005488 binding