Motif ID: REST.p3

Z-value: 3.794


Transcription factors associated with REST.p3:

Gene SymbolEntrez IDGene Name
REST 5978 RE1-silencing transcription factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RESTchr4_+_574691220.495.2e-02Click!


Activity profile for motif REST.p3.

activity profile for motif REST.p3


Sorted Z-values histogram for motif REST.p3

Sorted Z-values for motif REST.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of REST.p3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_134447795 19.795 NM_020064
BARHL1
BarH-like homeobox 1
chr2_-_27384617 14.421 NM_003353
UCN
urocortin
chr3_+_9720509 13.523 NM_153635
CPNE9
copine family member IX
chr8_-_145530639 12.309 NM_031309
SCRT1
scratch homolog 1, zinc finger protein (Drosophila)
chr6_+_110406890 11.072 NM_005284
GPR6
G protein-coupled receptor 6
chr5_-_151284515 10.969 NM_000171
NM_001146040
GLRA1

glycine receptor, alpha 1

chr4_+_158361185 10.352 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr5_+_71050745 10.229 NM_004291
CARTPT
CART prepropeptide
chr15_+_65904994 9.975 NM_001031807
SKOR1
SKI family transcriptional corepressor 1
chr7_+_154943466 9.089 NM_001427
EN2
engrailed homeobox 2
chr7_-_19778928 8.682 NM_152774
TMEM196
transmembrane protein 196
chr10_+_26545599 8.601 GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr8_-_57521065 8.543 NM_006211
PENK
proenkephalin
chr19_-_60383280 8.168 NM_003180
SYT5
synaptotagmin V
chr20_+_30019465 7.418 NM_001011718
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr14_-_50631407 7.287 TRIM9
tripartite motif containing 9
chr12_-_3472245 7.271 LOC100129223
hypothetical LOC100129223
chr5_+_33972247 7.188 NM_016568
RXFP3
relaxin/insulin-like family peptide receptor 3
chr8_+_57520915 7.187


chr20_+_44091219 6.990 NM_020708
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr20_+_44091265 6.835 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr9_-_138236775 6.698 NM_178138
LHX3
LIM homeobox 3
chr3_-_133236447 6.563 NM_130808
CPNE4
copine IV
chr11_+_22316242 6.423 NM_020346
SLC17A6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr11_-_74819165 6.367 NM_001039548
KLHL35
kelch-like 35 (Drosophila)
chr11_-_74818858 6.367 KLHL35
kelch-like 35 (Drosophila)
chr3_-_48675321 6.330 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr8_-_91164100 6.328 NM_004929
CALB1
calbindin 1, 28kDa
chr11_-_27698800 6.302 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr11_+_627268 6.194 NM_000797
DRD4
dopamine receptor D4
chr2_+_207215386 6.121 NM_001102659
LOC200726
hCG1657980
chr1_-_149955870 5.910 NM_007185
CELF3
CUGBP, Elav-like family member 3
chr3_+_122109716 5.854 NM_014980
STXBP5L
syntaxin binding protein 5-like
chr20_-_10148137 5.839 LOC100131208
similar to hCG2045825
chr11_-_74818685 5.781 KLHL35
kelch-like 35 (Drosophila)
chr11_-_122357545 5.630 NM_001098169
BSX
brain-specific homeobox
chr17_+_1120607 5.552 NM_001164405
BHLHA9
basic helix-loop-helix family, member a9
chr14_+_92459197 5.440 NM_001275
CHGA
chromogranin A (parathyroid secretory protein 1)
chr14_-_73962557 5.318 NM_001105579
TMEM90A
transmembrane protein 90A
chr17_-_24357014 5.195 NM_001098635
NM_178860
SEZ6

seizure related 6 homolog (mouse)

chr1_+_208178160 4.858 NM_001146261
NM_001146262
NM_001146264
NM_153262
SYT14



synaptotagmin XIV



chr14_-_50631794 4.847 TRIM9
tripartite motif containing 9
chr10_+_26545241 4.841 NM_000818
NM_001134366
GAD2

glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)

chr4_-_175986952 4.762 NM_001042543
NM_006529
GLRA3

glycine receptor, alpha 3

chr1_+_208178198 4.732 SYT14
synaptotagmin XIV
chr9_+_139153409 4.577 NM_000832
NM_001185090
NM_001185091
NM_007327
NM_021569
GRIN1




glutamate receptor, ionotropic, N-methyl D-aspartate 1




chr14_+_92459244 4.562 CHGA
chromogranin A (parathyroid secretory protein 1)
chr19_-_45416043 4.534 TTC9B
tetratricopeptide repeat domain 9B
chr14_-_104142125 4.427 NM_207379
TMEM179
transmembrane protein 179
chr19_-_45416112 4.199 NM_152479
TTC9B
tetratricopeptide repeat domain 9B
chr6_+_154402135 3.834 NM_000914
NM_001008503
NM_001008504
NM_001008505
NM_001145282
NM_001145283
NM_001145285
NM_001145286
NM_001145284
OPRM1








opioid receptor, mu 1








chr7_-_100595552 3.784 NM_003378
VGF
VGF nerve growth factor inducible
chr7_+_8440541 3.759 NXPH1
neurexophilin 1
chr15_-_70399181 3.739 CELF6
CUGBP, Elav-like family member 6
chr3_-_188870799 3.669 NM_001048
SST
somatostatin
chr15_+_73074882 3.605 NM_001178111
NM_001178112
NM_138967
SCAMP5


secretory carrier membrane protein 5


chr11_+_45863774 3.479 NM_005456
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr4_+_8633116 3.425 NM_080819
GPR78
G protein-coupled receptor 78
chr2_-_51112743 3.421 NRXN1
neurexin 1
chr1_+_33124658 3.408 NM_002143
HPCA
hippocalcin
chr12_+_111714096 3.375 RPH3A
rabphilin 3A homolog (mouse)
chr1_-_102234959 3.314 OLFM3
olfactomedin 3
chr3_-_115380539 3.182 NM_000796
NM_033663
DRD3

dopamine receptor D3

chr16_+_66244314 3.123 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr5_-_135729062 3.114 NM_001167576
NM_001167577
NM_020389
TRPC7


transient receptor potential cation channel, subfamily C, member 7


chr7_+_8440109 3.107 NM_152745
NXPH1
neurexophilin 1
chr15_-_70399301 2.979 NM_001172684
CELF6
CUGBP, Elav-like family member 6
chr6_+_158877640 2.922 TMEM181
transmembrane protein 181
chr20_-_60228665 2.899 NM_007232
HRH3
histamine receptor H3
chr12_+_111713931 2.835 NM_001143854
NM_014954
RPH3A

rabphilin 3A homolog (mouse)

chr1_+_152806874 2.786 NM_000748
CHRNB2
cholinergic receptor, nicotinic, beta 2 (neuronal)
chr15_-_24570010 2.784 NM_021912
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr12_-_97812633 2.763 ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr18_-_39111243 2.719 NM_020783
SYT4
synaptotagmin IV
chr12_-_29828958 2.684 NM_175861
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr17_+_77925441 2.624 NM_018949
UTS2R
urotensin 2 receptor
chr20_-_61755145 2.560 NM_015894
STMN3
stathmin-like 3
chr19_-_44427446 2.438 NM_172139
IL28B
interleukin 28B (interferon, lambda 3)
chr1_-_102235377 2.419 NM_058170
OLFM3
olfactomedin 3
chr12_+_117903682 2.411 NM_194286
SRRM4
serine/arginine repetitive matrix 4
chr15_-_70399551 2.379 NM_052840
CELF6
CUGBP, Elav-like family member 6
chr11_-_125278296 2.303 NM_031307
PUS3
pseudouridylate synthase 3
chr7_+_145444385 2.293 NM_014141
CNTNAP2
contactin associated protein-like 2
chr17_+_70178911 2.281 RAB37
RAB37, member RAS oncogene family
chr12_-_29827952 2.196 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr17_+_70178850 2.152 NM_175738
RAB37
RAB37, member RAS oncogene family
chr10_+_69990050 2.059 NM_030625
TET1
tet oncogene 1
chr15_-_70399523 2.039 CELF6
CUGBP, Elav-like family member 6
chr19_+_4720144 2.025 C19orf30
chromosome 19 open reading frame 30
chr12_+_46133 2.019 NM_001170738
IQSEC3
IQ motif and Sec7 domain 3
chr6_+_158877455 1.819 NM_020823
TMEM181
transmembrane protein 181
chr10_-_44200458 1.797 NM_000609
NM_001033886
NM_001178134
NM_199168
CXCL12



chemokine (C-X-C motif) ligand 12



chr19_+_45728270 1.792 SPTBN4
spectrin, beta, non-erythrocytic 4
chr1_-_239587090 1.679 NM_002924
RGS7
regulator of G-protein signaling 7
chr2_+_114916368 1.677 NM_020868
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr17_-_3248453 1.660 NM_003553
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr9_-_73251639 1.635 TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr8_-_145723209 1.627 NM_001024678
LRRC24
leucine rich repeat containing 24
chr5_+_175231098 1.555 NM_001008220
CPLX2
complexin 2
chr10_+_60607232 1.496 NM_001143774
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chrX_-_47364039 1.492


chr6_+_25760352 1.446 NM_006998
SCGN
secretagogin, EF-hand calcium binding protein
chr3_+_62279707 1.409 C3orf14
chromosome 3 open reading frame 14
chr5_+_175231170 1.393


chr7_+_8439762 1.346 NXPH1
neurexophilin 1
chr5_+_175231210 1.339 CPLX2
complexin 2
chrX_-_47364173 1.334 NM_006950
NM_133499
SYN1

synapsin I

chr16_+_2959362 1.282 PAQR4
progestin and adipoQ receptor family member IV
chr10_-_50640327 1.272 NM_001143996
NM_001143997
NM_018245
OGDHL


oxoglutarate dehydrogenase-like


chr19_+_45728207 1.239 NM_025213
SPTBN4
spectrin, beta, non-erythrocytic 4
chr11_-_1725924 1.239 NM_001170820
LOC402778
CD225 family protein FLJ76511
chr16_+_2959342 1.226 NM_152341
PAQR4
progestin and adipoQ receptor family member IV
chr10_-_102780840 1.223 PDZD7
PDZ domain containing 7
chr18_-_5187240 1.183 NM_001145194
LOC642597
hypothetical protein LOC642597
chr10_-_102780867 1.155 NM_001195263
NM_024895
PDZD7

PDZ domain containing 7

chr2_-_51113040 1.088 NM_001135659
NM_004801
NRXN1

neurexin 1

chr5_-_175969697 1.043 NM_052899
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr15_+_67009892 0.944 NM_145658
NM_001184780
SPESP1
NOX5
sperm equatorial segment protein 1
NADPH oxidase, EF-hand calcium binding domain 5
chr17_+_39741306 0.929 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chr6_+_153113624 0.923 NM_003381
NM_194435
VIP

vasoactive intestinal peptide

chr2_+_131230252 0.907 NM_001105194
NM_001105195
FAM123C

family with sequence similarity 123C

chr3_+_52787478 0.878 NM_001166434
ITIH1
inter-alpha (globulin) inhibitor H1
chr1_+_152806924 0.859 CHRNB2
cholinergic receptor, nicotinic, beta 2 (neuronal)
chr15_-_29950070 0.854 OTUD7A
OTU domain containing 7A
chrX_-_152794478 0.832 L1CAM
L1 cell adhesion molecule
chr11_-_6633427 0.827 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr10_+_102780974 0.813 NM_030971
SFXN3
sideroflexin 3
chr1_-_239587007 0.781 RGS7
regulator of G-protein signaling 7
chr11_-_1725662 0.742 LOC402778
CD225 family protein FLJ76511
chr16_+_24175173 0.728 CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr8_+_69027143 0.698 NM_024870
NM_025170
PREX2

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2

chr8_+_69026895 0.675 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr15_-_29950188 0.668 OTUD7A
OTU domain containing 7A
chr17_-_3283884 0.652 NM_003554
OR1E2
olfactory receptor, family 1, subfamily E, member 2
chr8_+_69027277 0.646 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr19_-_50429306 0.641 NM_138568
EXOC3L2
exocyst complex component 3-like 2
chr8_+_80685859 0.630 STMN2
stathmin-like 2
chr1_-_33108876 0.618 NM_001171940
NM_153756
FNDC5

fibronectin type III domain containing 5

chr5_+_175231144 0.600 CPLX2
complexin 2
chr16_+_24174975 0.586 CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr12_+_112280757 0.574 PLBD2
phospholipase B domain containing 2
chr3_+_62280435 0.546 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr1_-_151390050 0.499 NM_001014291
SPRR2G
small proline-rich protein 2G
chrX_-_152794592 0.498 NM_000425
NM_001143963
NM_024003
L1CAM


L1 cell adhesion molecule


chr11_-_123030091 0.483 SCN3B
sodium channel, voltage-gated, type III, beta
chrX_-_48943582 0.441 NM_003179
SYP
synaptophysin
chr18_+_55718171 0.423 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr20_+_5839973 0.415 NM_001819
CHGB
chromogranin B (secretogranin 1)
chr5_+_141283550 0.407 NM_001142603
NM_014773
KIAA0141

KIAA0141

chr6_+_35881048 0.393 NM_182548
LHFPL5
lipoma HMGIC fusion partner-like 5
chr20_+_35445350 0.322 SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr12_+_112280753 0.295 NM_001159727
NM_173542
PLBD2

phospholipase B domain containing 2

chr17_-_3546236 0.282 NM_002561
NM_175080
NM_175081
P2RX5-TAX1BP3
P2RX5


P2RX5-TAX1BP3 read-through transcript
purinergic receptor P2X, ligand-gated ion channel, 5


chr17_-_7095622 0.266 NM_001143775
CTDNEP1
CTD nuclear envelope phosphatase 1
chr5_+_141283647 0.241 KIAA0141
KIAA0141
chr19_+_38867273 0.222 NM_022467
CHST8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr19_+_51804260 0.155 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr19_-_50618599 0.139 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr6_-_32121784 0.138 NM_032470
TNXB
tenascin XB
chr1_+_100777044 0.112 GPR88
G protein-coupled receptor 88
chr11_-_27677755 0.110 NM_170734
BDNF
brain-derived neurotrophic factor
chrX_+_152891184 0.100 NM_003492
TMEM187
transmembrane protein 187
chr1_-_20707103 0.096 MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr1_-_20707196 0.072 NM_024544
MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr10_+_73225533 0.066 NM_001171933
NM_001171934
CDH23

cadherin-related 23

chr8_-_94046891 0.054 NM_001191036
C8orf83
chromosome 8 open reading frame 83
chr11_-_72170533 0.054 STARD10
StAR-related lipid transfer (START) domain containing 10
chr2_-_96174502 0.049 DUSP2
dual specificity phosphatase 2
chr22_-_16636748 0.042 NM_197966
BID
BH3 interacting domain death agonist
chr11_+_64565118 0.025 SAC3D1
SAC3 domain containing 1
chr11_+_62136788 0.016 NM_000327
ROM1
retinal outer segment membrane protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
8.12 1.76e-11 GO:0007268 synaptic transmission
7.56 1.94e-11 GO:0019226 transmission of nerve impulse
7.56 1.94e-11 GO:0035637 multicellular organismal signaling
3.52 2.70e-09 GO:0003008 system process
3.91 3.22e-09 GO:0050877 neurological system process
4.92 1.32e-07 GO:0007267 cell-cell signaling
5.57 7.80e-07 GO:0007186 G-protein coupled receptor protein signaling pathway
4.02 1.25e-06 GO:0007154 cell communication
7.09 7.19e-06 GO:0007610 behavior
5.84 9.59e-06 GO:0046903 secretion
10.72 2.17e-05 GO:0031644 regulation of neurological system process
2.10 4.50e-05 GO:0023052 signaling
10.66 1.15e-04 GO:0051969 regulation of transmission of nerve impulse
1.80 2.04e-04 GO:0032501 multicellular organismal process
5.03 4.97e-04 GO:0055082 cellular chemical homeostasis
4.84 1.96e-03 GO:0006873 cellular ion homeostasis
11.06 2.24e-03 GO:0007626 locomotory behavior
5.56 3.23e-03 GO:0032940 secretion by cell
19.84 3.34e-03 GO:0051952 regulation of amine transport
7.11 3.43e-03 GO:0055074 calcium ion homeostasis
3.95 3.97e-03 GO:0048878 chemical homeostasis
6.85 4.63e-03 GO:0072507 divalent inorganic cation homeostasis
4.47 4.69e-03 GO:0050801 ion homeostasis
4.15 4.70e-03 GO:0019725 cellular homeostasis
9.70 5.36e-03 GO:0003001 generation of a signal involved in cell-cell signaling
9.70 5.36e-03 GO:0023061 signal release
5.22 5.89e-03 GO:0044057 regulation of system process
2.28 7.50e-03 GO:0065008 regulation of biological quality
9.18 7.70e-03 GO:0050804 regulation of synaptic transmission
26.69 9.23e-03 GO:0014073 response to tropane
26.69 9.23e-03 GO:0042220 response to cocaine
24.47 1.33e-02 GO:0060078 regulation of postsynaptic membrane potential
48.93 1.71e-02 GO:0010155 regulation of proton transport
22.59 1.85e-02 GO:0050433 regulation of catecholamine secretion
10.13 1.91e-02 GO:0001505 regulation of neurotransmitter levels
21.75 2.16e-02 GO:0045776 negative regulation of blood pressure
6.53 2.16e-02 GO:0006874 cellular calcium ion homeostasis
1.96 2.29e-02 GO:0051234 establishment of localization
4.97 2.34e-02 GO:0051046 regulation of secretion
6.32 2.73e-02 GO:0072503 cellular divalent inorganic cation homeostasis
6.29 2.84e-02 GO:0003013 circulatory system process
6.29 2.84e-02 GO:0008015 blood circulation
4.80 3.10e-02 GO:0055080 cation homeostasis
40.04 3.32e-02 GO:0032225 regulation of synaptic transmission, dopaminergic
1.93 4.05e-02 GO:0006810 transport
11.84 4.33e-02 GO:0007269 neurotransmitter secretion
36.70 4.41e-02 GO:0032413 negative regulation of ion transmembrane transporter activity
8.73 4.45e-02 GO:0006836 neurotransmitter transport
8.56 4.96e-02 GO:0008217 regulation of blood pressure

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
8.70 1.27e-09 GO:0044456 synapse part
6.84 1.62e-08 GO:0045202 synapse
17.07 4.22e-08 GO:0008021 synaptic vesicle
26.10 8.07e-08 GO:0030672 synaptic vesicle membrane
6.12 9.16e-07 GO:0043005 neuron projection
4.29 4.45e-06 GO:0016023 cytoplasmic membrane-bounded vesicle
4.21 6.07e-06 GO:0031988 membrane-bounded vesicle
4.04 1.20e-05 GO:0031410 cytoplasmic vesicle
13.82 1.44e-05 GO:0030665 clathrin coated vesicle membrane
9.18 1.78e-05 GO:0030136 clathrin-coated vesicle
3.91 2.03e-05 GO:0031982 vesicle
6.81 2.55e-05 GO:0030659 cytoplasmic vesicle membrane
6.58 3.68e-05 GO:0012506 vesicle membrane
4.39 3.79e-05 GO:0030054 cell junction
7.50 1.17e-04 GO:0030135 coated vesicle
10.22 1.49e-04 GO:0030662 coated vesicle membrane
5.65 1.84e-04 GO:0044433 cytoplasmic vesicle part
3.41 3.39e-04 GO:0042995 cell projection
6.87 2.83e-03 GO:0043025 neuronal cell body
6.68 3.48e-03 GO:0044297 cell body
2.16 3.83e-03 GO:0044459 plasma membrane part
6.22 5.79e-03 GO:0030425 dendrite
1.44 6.06e-03 GO:0016020 membrane
1.52 6.99e-03 GO:0044425 membrane part
8.90 7.51e-03 GO:0019717 synaptosome
6.95 8.77e-03 GO:0045211 postsynaptic membrane
1.56 1.35e-02 GO:0031224 intrinsic to membrane
1.56 1.63e-02 GO:0016021 integral to membrane
25.91 2.51e-02 GO:0032589 neuron projection membrane
73.39 3.52e-02 GO:0032590 dendrite membrane
1.64 3.79e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
14.28 7.79e-05 GO:0005230 extracellular ligand-gated ion channel activity
18.74 1.01e-04 GO:0005231 excitatory extracellular ligand-gated ion channel activity
27.96 1.51e-03 GO:0005184 neuropeptide hormone activity
8.23 3.14e-03 GO:0015276 ligand-gated ion channel activity
8.23 3.14e-03 GO:0022834 ligand-gated channel activity
4.25 7.84e-03 GO:0005216 ion channel activity
8.90 7.91e-03 GO:0005179 hormone activity
4.18 9.02e-03 GO:0022838 substrate-specific channel activity
33.88 1.13e-02 GO:0016594 glycine binding
4.05 1.18e-02 GO:0015267 channel activity
4.04 1.21e-02 GO:0022803 passive transmembrane transporter activity
97.85 1.86e-02 GO:0001591 dopamine receptor activity, coupled via Gi/Go
7.17 2.63e-02 GO:0043176 amine binding
4.40 2.93e-02 GO:0022836 gated channel activity
2.46 3.20e-02 GO:0005215 transporter activity
73.39 3.71e-02 GO:0016933 extracellular-glycine-gated ion channel activity
73.39 3.71e-02 GO:0016934 extracellular-glycine-gated chloride channel activity
3.05 4.58e-02 GO:0005509 calcium ion binding